Actinacidiphila glaucinigra: OIE69_28895
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Entry
OIE69_28895 CDS
T09685
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
agla
Actinacidiphila glaucinigra
Pathway
agla00300
Lysine biosynthesis
agla00550
Peptidoglycan biosynthesis
agla01100
Metabolic pathways
agla01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
agla00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
OIE69_28895
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
OIE69_28895
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
OIE69_28895
Enzymes [BR:
agla01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
OIE69_28895
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DHHA1
Motif
Other DBs
NCBI-ProteinID:
WSD62624
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Position
6420548..6421972
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AA seq
474 aa
AA seq
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MIPLTLAEVAHAVGGSTHDIPDPTLPVTGSVEIDSRKVTPGGLFVAFQGEHVDGHDYAKQ
AVAAGAVAVLAARPVGVPAIVVDDVQLALGALAAQVIERLGATLVALTGSAGKTSTKDLT
AQVLKRLAPTVWTPGSLNNEIGLPLTALRADASTRHLVLEMGARGIGHIRYLTELTPPRI
GVVLNVGTAHIGEFGGREQIAQAKGELVEALPEAAEGGVAVLNADDPLVRAMSSRTAARV
VLFGESADADVRAENVRLNDRGQAVFALTTPTGCSEVTLRLYGEHHVSNALAAAAVAREL
GMPVDEIATALSEAGTLSRWRMEVVERPDGVTVVNDAYNANPESMRAALRALAAMGRAAE
ARGGRTWAVLGEMAELGGEALAEHDAVGRLAVRLNVSKLVAVGGQAAAWVQMGAYNEGSW
GEESVHVSDAEAAIDLLRSELRPGDVVLVKASRAVGLERVALALLDGVEGGGAQ
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcccactcaccctcgccgaggtcgcacacgcggtcggcgggagcacgcacgacata
ccggacccgacgctgcccgtcaccgggtccgtcgagatcgactcccgcaaggtgacgccg
ggcggcctgttcgtcgctttccagggcgagcacgtggacggccacgactacgcgaagcag
gccgtcgcggccggggcggtggccgtgctggccgcccggccggtcggcgtgcccgcgatc
gtcgtggacgacgtccagctcgccctcggcgccctggccgcgcaggtcatcgaacggctc
ggcgcgaccctcgtggcgctgaccggatcggcgggcaagaccagcaccaaggacctcacc
gcacaggtgctcaagcggctggctccgaccgtctggacgcccggctcgctcaacaacgag
atcgggctgccgttgaccgcgctgcgcgccgacgcctccacccggcacctggtgctggag
atgggcgcccgcggcatcggccacatccgctacctcaccgagctgaccccgccgcgcatc
ggcgtcgtcctcaacgtcggtaccgcccacatcggcgagttcggcggccgcgagcagatc
gcccaggccaagggcgagctggtcgaggcgctgccggaggccgccgaaggcggcgtcgcc
gtgctgaatgcggacgatcccctcgtacgcgccatgtcctcccgcaccgcggcgcgcgtc
gtgctgttcggcgagtccgccgacgccgacgtccgcgccgagaacgtccgcctcaacgac
cgaggtcaggccgtcttcgcgctcacaacacctaccgggtgcagcgaagtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgcttgccgcggccgccgttgcccgtgaactc
ggcatgcccgtcgacgagatcgccaccgcgctctccgaggcggggacgctgtcccgctgg
cgtatggaggtcgtcgaacggcctgacggcgtaacggtcgtgaacgacgcctacaacgcg
aaccccgagtccatgcgagccgccctgcgcgcgctcgcggccatggggcgtgccgccgag
gcacgcgggggacgcacgtgggcggtgctgggcgagatggcggagctcggcggggaggcc
ctcgcggagcacgacgctgtcggacggctcgccgtccggctcaacgtcagcaagctcgtg
gcagtcggcggccaggcggccgcctgggtgcaaatgggcgcctacaacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgctgaggcggcgatcgacctgctgcgcagtgaa
ctgcgtccgggggacgtcgtgctggtgaaggcatcgagggcggtcggcctggagcgggtc
gcactcgcgctgctcgacggcgtcgagggcgggggcgctcagtaa
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