Aeromonas hydrophila subsp. hydrophila ATCC 7966: AHA_2722
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Entry
AHA_2722 CDS
T00424
Symbol
leuA-2
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
aha
Aeromonas hydrophila subsp. hydrophila ATCC 7966
Pathway
aha00290
Valine, leucine and isoleucine biosynthesis
aha00620
Pyruvate metabolism
aha01100
Metabolic pathways
aha01110
Biosynthesis of secondary metabolites
aha01210
2-Oxocarboxylic acid metabolism
aha01230
Biosynthesis of amino acids
Module
aha_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
aha00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AHA_2722 (leuA-2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AHA_2722 (leuA-2)
Enzymes [BR:
aha01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AHA_2722 (leuA-2)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
BP74_N
Motif
Other DBs
NCBI-ProteinID:
ABK37815
UniProt:
A0KLS9
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All DBs
Position
complement(3058555..3060213)
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AA seq
552 aa
AA seq
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MSFDHRKYRRAPVINLADRQWPNRVLERAPLWCAVDLRDGNQALVEPMTVAQKLQMWALM
VHIGFKHIEVGFPAASQPDFDFVRELIDRNLIPDDVTIQVLVQAREDLIARTFEALKGAK
RAIVHVYNSVNPTQRNYVFNSGREGVKAIAVQGARWVREYAARNSGTEWSFQYSPESFSC
TEVEFAVEVCDAVIDQWRPAARPMILNLPATVEVSTPNVFADQVEWFCRHLKARPEVSIS
IHTHNDRGCGVAAAELAVLAGADRIEGTLLGNGERTGNMDIVTMAMNLYSQGIDPELNLA
DMDAIVATVGACTQIALHPRHPYAGELVYTAFSGSHQDAIRKSLAAEKPDHYWDVAYLPI
DPADLGRSYEAVIRINSQSGKGGVTYLLERDLGLQLPRWLQIDFSRRVQAEAEASSSEIS
PEQIRSLFERHYLEPAHGYRIGRFQLGRDSQESLRLELQTPTGSLQLSGEGEGAITALVN
GWQRQTGMHIDVLDYSEHALSAGTESRAAAYVLLSVDGTRTCGVAIGRDVVSASLQAVIN
GAAQIEALRQSA
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atgagcttcgatcatcgcaaataccgccgtgcccccgtcatcaatctggcggatcgccag
tggcccaaccgggtgctggagcgggcgccgctctggtgcgccgtggatctgcgcgacggc
aaccaggcgctggtcgagccgatgacggtggcgcagaagctgcagatgtgggcgctgatg
gtgcacatcggcttcaagcacatcgaggtgggctttccggccgcctctcagcccgatttt
gacttcgtgcgcgagcttatcgatcgcaatctcattccggacgacgtcaccatccaggtg
ttggtacaggcgcgcgaagatctgatagcccgcaccttcgaggccctcaagggggccaag
cgggccatcgtccacgtctacaactcggtcaacccgacccagcgcaactatgtgttcaac
tcagggcgcgaaggggtcaaggccatcgccgtgcagggggcgcgttgggtgcgggagtat
gcggcccgcaattcgggcaccgagtggagttttcagtactcgccggagagtttcagctgc
accgaggtggagttcgccgtcgaggtgtgtgacgcggtgatcgaccagtggcgcccggcg
gcccgcccgatgatcctgaacctgcccgccaccgtggaggtgagcacccccaacgtgttt
gccgatcaggtggagtggttctgccgccacctcaaggcgcgccccgaggtgagtatctcc
atccatacccacaacgatcggggctgcggggtggccgccgccgagttggcggtgttggcg
ggggcggatcgcatcgagggcaccctgctcggcaacggtgagcgcaccggcaacatggac
atcgtcaccatggccatgaacctctacagccaggggatcgaccccgagctcaacctggcg
gacatggatgccatcgtcgccaccgtgggagcctgcacccagattgccctgcacccgcgc
cacccctatgccggcgagctggtctacacggcgttttccggcagccaccaggacgccatc
cgcaaatccctggcggcggagaagccggatcactactgggacgtggcttacctgcccatc
gatcctgccgatctcggtcgcagctacgaggcggtgatccgcatcaacagccagtccggc
aaggggggcgttacctacctgctggagcgcgatcttggtctgcaactgccgcgttggctg
caaattgacttcagccgccgggtacaagccgaggctgaggcgagcagcagcgagataagt
ccggagcagatccgctccctgttcgagcgtcactatctcgaacccgcccacggctatcgc
atcggtcgcttccagctcggtcgcgacagccaggagagcctgcgcctcgaactgcagacc
ccgaccggctcgctgcagttgagcggtgaaggggagggggccatcacggcgctggtcaac
ggctggcagcgtcagaccgggatgcacatcgacgtgctggattactccgagcatgcctta
agcgccggcaccgagtcccgcgccgccgcctacgtgctgctgagtgtcgacgggacccgc
acctgcggggtggccatcggccgcgatgtggtcagcgcctccctgcaggcggtgatcaat
ggcgccgcccagatagaggcgctgcgccagagcgcctga
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