Aeromonas hydrophila subsp. hydrophila ATCC 7966: AHA_3888
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Entry
AHA_3888 CDS
T00424
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aha
Aeromonas hydrophila subsp. hydrophila ATCC 7966
Pathway
aha00300
Lysine biosynthesis
aha00550
Peptidoglycan biosynthesis
aha01100
Metabolic pathways
aha01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aha00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AHA_3888 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AHA_3888 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AHA_3888 (murF)
Enzymes [BR:
aha01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AHA_3888 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABK37729
UniProt:
A0KPX6
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All DBs
Position
complement(4319894..4321249)
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AA seq
451 aa
AA seq
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MMTLRLAELAQVLDARLIGEDGAITAVSTDTRTLGAGALFVALRGERFDAHDFCEQAVAA
GASALLVERELPLAIPQLVVTDSLKGLGRLGRLVRERINPKVLAITGSCGKTTVKEMATA
ILRQEGDVLATAGNFNNEVGVPLTLLRLEPQHRFAVMELGANHPGEIAWTTSLAKPDAAI
INNVAAAHLEGFGSLEGVFHAKSEIFEGLGEGGTAIVNADNEFWPKWQARGIHCAFSIED
QRQPFHARNVVINQQGCAEFVMVTPQGEISLTLAIPGRHNVANALAAAAGTLALGASLAS
VKAGLELMAPVKGRFCVQRWGGLTLVDDTYNASVESVLAGIDALTAMSGYKVLVFGDMKE
LGEESAEQHARVGRHASERGLDAVLTVGEQSRHTADAAAGRHFDNKASLFEVLAQMINTH
QEIAILVKGARGSRMEDIVEMVKDRQESATC
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atgatgaccctcaggcttgccgagctggcgcaggtactcgatgcccgtctgattggtgaa
gacggagcgatcacggctgtcagcaccgacacccgtaccctgggcgcaggcgcgctgttt
gttgcgctgcgcggcgagcgtttcgatgcccacgatttctgcgagcaggccgtggccgcc
ggagcatcggcccttctggtcgagcgtgaactgccgttggcgatcccccagctggtggtg
accgacagtctcaagggactgggtcgcctcggtcggttggtgcgcgagcggatcaacccg
aaagtgctggccatcaccggcagctgtggcaagaccactgtgaaggagatggcgaccgcc
atcctgcgtcaggaaggggacgtgctggccaccgccggcaacttcaacaacgaagtgggg
gtgccgctgaccctgctgcgcctcgagccgcaacaccggtttgcggtgatggagctgggg
gccaaccacccgggcgagatcgcctggactacctcgttggccaaacccgatgccgccatc
atcaacaacgtggcggccgcccacctggagggcttcggctcgctggaaggggtgtttcac
gccaagagcgaaatcttcgaggggctgggcgagggcggaaccgccatcgtcaatgccgac
aacgaattctggccaaagtggcaggcccgcgggatccactgcgccttctccatcgaggat
cagcgtcagccgttccacgccagaaacgtggtgatcaaccagcagggttgtgccgagttt
gtcatggtgaccccgcagggtgaaataagcctgaccctggccattccgggccgccataac
gtggcgaacgccctggccgccgccgctggcacgctggcgctcggcgcctcgctcgcctcg
gtcaaggccgggctcgagctgatggcaccggtcaagggccgtttctgcgtccagcgctgg
ggtggtctcaccctggtggacgacacctacaacgccagcgtggagtccgtgctggcgggc
atcgatgccctgaccgccatgagtggctacaaggtgctggtgttcggtgacatgaaggag
ttgggtgaggagtccgccgagcagcacgcccgggtcggacgccacgccagcgagcgcggc
ctcgatgccgtgctgaccgtaggggaacagagtcgccacaccgcagatgccgcggctggc
cgacatttcgataacaaggcgtcgttgtttgaagtgcttgcgcaaatgataaatacacat
caagaaatcgccatcctggtcaagggtgcccgcggctcccgcatggaagatatcgtcgag
atggtcaaagaccgtcaggagtcagccacatgctag
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