Aeromonas hydrophila YL17: AI20_04305
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Entry
AI20_04305 CDS
T03186
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ahd
Aeromonas hydrophila YL17
Pathway
ahd00260
Glycine, serine and threonine metabolism
ahd00261
Monobactam biosynthesis
ahd00270
Cysteine and methionine metabolism
ahd00300
Lysine biosynthesis
ahd01100
Metabolic pathways
ahd01110
Biosynthesis of secondary metabolites
ahd01120
Microbial metabolism in diverse environments
ahd01230
Biosynthesis of amino acids
Module
ahd_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ahd_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
ahd_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ahd00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
AI20_04305 (thrA)
00270 Cysteine and methionine metabolism
AI20_04305 (thrA)
00300 Lysine biosynthesis
AI20_04305 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
AI20_04305 (thrA)
Enzymes [BR:
ahd01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
AI20_04305 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
AI20_04305 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AHV34446
LinkDB
All DBs
Position
complement(4482656..4485115)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADAERFLRVADIAVNTHGQSQVALVLSAPAKVTNHLVALVEQTSRGMDA
SSTLFEINGIFSRLLAGLKAAYPALDDKALQARLTSELDQVERLMQGIRLLGLCPDNVQA
RILSRGENLSIAFMHELLRVRGLELDLIVPEELLVTDGGYLEAHVDIEASRLRFAAKGLR
SDCLYLMPGFTGGSDKGETVLLGRNGSDYSAAVLAACVDAECCEIWTDVEGCYNCDPRLV
PDAYLLKTLSYKEAMELSYFGAKVLHPKTIAPVAQFHIPCLIKNSFNPQGPGTLIGVEQG
DDDLKVKAISDLSGMCMFNVSGPGMKGMVGMAGRIFSAVSRAGVSIVLITQSSSEYSVSF
CIHSYDCDKTRKVLEREFELEFKNQLLDPLEIMQDLAIISLIGDGMRTSKGMAARFFTSL
AQASINIVAIAQGSSERSISAVVRDRKVAEAIKACHQNFFGSQQFIDLFVVGVGGVGAAL
VDQIARQQPVLAEQGTGLRVVGIANSRQMAVNKDGLNLANWREQLVEARDSFSLEAVKKL
VEESHLINPVIVDCTSSEAIAVQYADFLAAGFHVVTPNKKANTGSLDYYKALRRTARQTR
RKFLYETNVGAGLPVIENLQNLIKAGDKLRAFDGVLSGSLSFIFGKLDEGMAFSDATKIA
RGNGFTEPDPRDDLNGMDVARKLLILAREAGMALELADVEVEQALPPGFDVSGDVESFMA
RLPEADGWFRDQFAAAQRDGKVLRYVGSIEGGKCKVAIKAVGADEPLFKVKDGENALAFF
STYYQPIPLVLRGYGAGTEVTAAGVFADVLRTQNWKQEL
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgagagtgttgaagtttggcgggtcgtcactggccgatgcagagcgttttttacgggtc
gccgatatcgcggtgaatacccacggccaatcccaggttgccctggtgctgtcggcaccg
gccaaggtgaccaaccacctggtggcgctggtggagcagaccagccgcggcatggatgcc
agcagcaccctgttcgagatcaacggtatcttctcccgcctgctggccggcttgaaggca
gcctatccggcgctggatgacaaggcgctgcaggcccgtctcaccagcgaactggatcag
gtggagcggctgatgcagggcatccgcctgctggggctctgcccggacaacgtgcaggct
cgcatcctgagccggggcgagaacctctccatcgccttcatgcacgagctgctgcgggtg
cgcggcctcgagctggacctcattgtgccggaagaactgctggtgaccgacggcggctac
ctcgaagctcacgtcgacatcgaagcctcccgcctgcgcttcgccgccaaggggttgcgt
agcgactgcctttacctgatgccgggcttcaccggtggcagcgacaagggcgaaaccgtg
ctgctgggccgtaacggctccgactactctgccgccgtgctggccgcctgcgtcgatgcc
gagtgctgcgagatctggaccgatgtcgagggctgctacaactgcgacccgcgcctggtg
ccggacgcctatctgctgaaaaccctctcctacaaggaggcgatggagctctcctacttc
ggtgccaaggtactgcatccgaaaaccatcgcgccggtggcccagttccacattccctgc
ctgatcaagaacagcttcaacccgcaggggccggggacgcttatcggcgtcgagcagggg
gatgacgacctgaaagtgaaggccatctcggatctctccggcatgtgcatgttcaacgtc
tccggccccggcatgaagggcatggtcggtatggctggccgcatcttctccgccgtctcc
cgcgccggggtcagcatcgtcctcatcacccagtcatcctccgagtacagcgtcagcttc
tgtatccacagctatgactgcgacaagacccgcaaggtgctggaacgcgagttcgagctc
gaattcaagaaccagctgctggatccgctggagatcatgcaggatctggcgatcatctcc
ctgatcggtgacggcatgcgcacctccaaggggatggcggcccgcttcttcacctcgctg
gctcaggcctccatcaacatcgtcgccattgcccagggctcgagcgagcgctccatctct
gccgtggtgcgggatcgcaaggtggcggaggccatcaaggcctgccaccagaacttcttc
ggcagccagcagttcatcgacttgttcgtggtcggcgtcggcggtgtcggcgcggccctg
gtggatcagattgcccgccagcagccggtattggccgagcagggcactggcctgcgggta
gtgggcatcgctaacagccgccagatggcggtcaacaaggatggcctgaacctcgccaac
tggcgtgaacagctggtggaagcccgtgacagcttcagcctggaggcggtgaagaagctg
gtggaagagagtcacctcatcaacccggtgatcgtcgattgcacttccagcgaggccatc
gccgtccagtacgccgacttcctcgccgccggtttccacgtggtcaccccgaacaagaag
gccaacactggctcgctcgattactacaaggcgctgcgccgcaccgcccgtcagacccgt
cgcaagttcctgtacgagaccaacgtgggcgccggcctgccggtcatcgagaacctgcag
aacctgatcaaggccggcgacaagctgcgcgccttcgacggtgtgctctccggttcgctc
tcctttatcttcggcaagctggacgaggggatggccttctccgatgccaccaagattgcc
cgtggcaacggttttaccgagccggatccgcgcgacgatctcaacggcatggacgtggcc
cgcaagctgctcattctggcccgcgaggctggtatggcgctggagctcgccgatgtggaa
gtggagcaggcgctgccgccgggctttgatgtgagcggcgacgtggaatcctttatggcc
cgcctgccggaggctgacggctggttccgcgaccagtttgcggccgcccagcgtgacggt
aaggtgctgcgctacgtgggttccatcgagggtggcaagtgcaaggtcgccatcaaggcg
gtcggcgccgacgaaccgctgttcaaggtcaaagacggggagaacgcgctcgccttcttc
tccacctactaccagccgatcccgctggtgctgcgcggctatggcgccggcaccgaagtg
accgccgcgggcgtctttgccgacgtgctgcgcacccagaactggaagcaggagttgtaa
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