Aeromonas hydrophila subsp. hydrophila AL09-71: V428_14960
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Entry
V428_14960 CDS
T03192
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ahr
Aeromonas hydrophila subsp. hydrophila AL09-71
Pathway
ahr00290
Valine, leucine and isoleucine biosynthesis
ahr00620
Pyruvate metabolism
ahr01100
Metabolic pathways
ahr01110
Biosynthesis of secondary metabolites
ahr01210
2-Oxocarboxylic acid metabolism
ahr01230
Biosynthesis of amino acids
Module
ahr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ahr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
V428_14960
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
V428_14960
Enzymes [BR:
ahr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
V428_14960
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
BP74_N
Motif
Other DBs
NCBI-ProteinID:
AHX33327
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All DBs
Position
complement(3267863..3269521)
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AA seq
552 aa
AA seq
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MSFDHRKYRRAPVINLADRQWPNRVLERAPLWCAVDLRDGNQALVEPMTVAQKLQMWALM
VHIGFKHIEVGFPAASQPDFDFVRELIDRNLIPDDVTIQVLVQAREDLIARTFEALKGAK
RAIVHVYNSVNPTQRNYVFNSGREGVKAIAVQGARWVREYAARNQGTEWSFQYSPESFSS
TEVEFAVEVCDAVIDQWRPAARPMILNLPATVEVSTPNVFADQVEWFCRHLKARPEVSIS
IHTHNDRGCGVAAAELAVLAGADRIEGTLLGNGERTGNMDIVTMAMNLYSQGIDPELNLA
DMDAIVATVGACTQIALHPRHPYAGELVYTAFSGSHQDAIRKSLAAEKPDHYWDVAYLPI
DPADLGRSYEAVIRINSQSGKGGVTYLLERDLGLQLPRWLQIDFSRRVQAEAEASSSEIS
PEQIRTLFERHYLEPAHGYRIGRFQLGRDSQESLRLELQTPTGSLQLSGEGEGAITALVN
GWQRQTGMHIDVLDYSEHALSAGTESRAAAYVLLSVDGTRTCGVAIGRDVVSASLQAVIN
GAAQIEALRQSA
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atgagcttcgatcatcgcaaataccgccgtgcccccgtcatcaatctggcggatcgccag
tggcccaaccgggtgctggagcgggccccgctctggtgcgccgtggatctgcgcgacggc
aaccaggcgctggtcgagcccatgacggtggcgcagaagctgcagatgtgggcgctgatg
gtgcacatcggcttcaagcacatcgaggtgggctttccggccgcctcccagcccgatttc
gacttcgtgcgcgagcttatcgaccgcaacctcattccggacgacgtcaccatccaggtg
ctggtgcaggcgcgcgaagatctgatcgcccgtaccttcgaggccctcaagggggccaag
cgggccatcgtccacgtctacaactcggtcaacccgacccagcgcaactatgtgttcaac
tcagggcgcgaaggggtcaaggccatcgccgtgcagggggcgcgctgggtgcgggagtat
gcggcccgcaatcagggtaccgagtggagttttcagtactcgccggagagcttcagcagc
acagaagtggagttcgcggtggaggtgtgcgacgccgtcatcgaccagtggcgcccggct
gcccgcccgatgatcctgaacctgcccgccaccgtggaggtgagcacccccaacgtgttt
gccgatcaggtggagtggttctgtcgtcacctcaaggcgcgccccgaggtgagcatctcc
attcacacccacaacgatcggggctgcggggtggctgccgccgagctggcggtgctggcg
ggagcggatcgcatcgagggcaccctgctcggcaacggtgagcgcaccggcaacatggac
attgtcaccatggccatgaacctctacagccaggggatcgatcccgaactcaacctggcg
gacatggatgccatcgtcgccaccgtgggggcctgcacccagattgccctgcacccgcgc
cacccctatgccggcgagctggtttacacggcgttttccggcagccaccaggacgccatc
cgcaagtctctcgcggcagaaaaacctgatcactactgggacgtggcttacctgcccatc
gatcctgccgatctcggccgcagctacgaggcggtgatccgcatcaacagccagtccggc
aagggaggggtcacctacctgctggagcgcgaccttggtctgcaactgccgcgctggctg
caaattgacttcagccgccgggtccaagccgaggcggaagcgagcagcagcgagataagc
ccggagcagatccgcaccctgttcgagcgccactatctcgaacccgcccacggctatcgc
atcggtcgcttccagcttggtcgcgacagccaggagagcctgcgcctcgagctgcagacc
ccgaccgggtcgctgcagctcagtggtgaaggggagggggccatcacggcgctggtcaac
ggctggcagcgccagaccgggatgcacatcgatgtgctggattactcggagcatgcctta
agcgccggtaccgagtcccgcgccgccgcctacgtgctgctgagcgtggacgggacccgc
acctgcggggtggccatcggccgcgacgtggtcagcgcctccctgcaggcggtgatcaat
ggcgccgcccagatagaggcgttgcgccagagcgcctga
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