Actinomyces howellii: NCTC11636_00819
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Entry
NCTC11636_00819 CDS
T06068
Symbol
fgs
Name
(GenBank) Folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ahw
Actinomyces howellii
Pathway
ahw00790
Folate biosynthesis
ahw01100
Metabolic pathways
ahw01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ahw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NCTC11636_00819 (fgs)
Enzymes [BR:
ahw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NCTC11636_00819 (fgs)
6.3.2.17 tetrahydrofolate synthase
NCTC11636_00819 (fgs)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
VEG27000
UniProt:
A0A448HFC3
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Position
1:complement(960498..962267)
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AA seq
589 aa
AA seq
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MNHSTPRDLGPLGPRGHDEEPAGVDPALLPYLEAADEPDRSLAEIDQAAREADLAEQERL
EEDRRALRELVAQGLIPGGDPDRLDELLAEVDEDGADDWQEWEPVLADAPEPAGGIDEEA
RHRADLEAAAREVETSARMRAVEAEILARAPEHHVQPSLERVEAALDILGNPERAYRVVH
VTGTNGKTSTARMIERLLAATGMRTGRFTSPHLATIRERISLDGEPVSEEGFIAAWEDVA
PYIEMVDAQSLKRGGPRMSFFEVLTVMALAAFADHPVDVAVIEVGLGGTWDSTNVVDSEV
EVITPVGRDHGRWLGESLEEVAANKAGIIKDGATLVTAHQPPEVEGVIAAAAAEHGVVWR
RELDPQEDPQAPGAGVLRVVDRTRAVGGQMVTLATAAAVYEDVFVPLHGQYQAHNALLAL
AAAEAVFGGRALPPLVVENGFASVTSPGRLEVLRSSPTVLLDAAHNPHGMEALVPAVEET
FGLRHLVVVLGVMADKDVEGILSVLEPACEAVVCVPIDSPRAIDPEDLAVQAREVFGEDR
VVLAQSLVEGVDRAVSLAEGFDAPMPATGVLIVGSVLLAAEARALFSRR
NT seq
1770 nt
NT seq
+upstream
nt +downstream
nt
atgaaccacagcacgccgcgcgacctcggtcccctcggcccccggggccacgacgaggag
cccgcgggggttgaccccgccctcctgccctacctcgaggcggcggacgagcccgaccgc
tccctggccgagatcgaccaggccgcccgtgaggcggacctggccgagcaggagcggctt
gaggaggaccggcgcgccctgcgtgagctcgtcgcccaggggctcatccccggcggggac
ccggaccggctcgacgagctcctggctgaggtcgacgaggacggagccgacgactggcag
gagtgggagcctgtcctggccgacgcccctgagccggccggcgggatcgacgaggaggcc
cgtcaccgggccgacctggaggcagcggcccgcgaggtcgagacgagcgcgcgcatgcgc
gccgtcgaggccgagatcctcgcgcgcgcccccgagcaccacgtccagccctccctcgag
cgggtcgaggcggccctcgacatcctgggcaaccccgagcgggcctaccgtgtcgtccac
gtcaccggcacgaacggcaagacctcgacggcgcggatgatcgagcgcctcctggcggcc
acgggcatgcgcaccgggcgcttcacctcccctcacctggccaccatccgtgagcgcatc
agcctcgacggcgagcccgtgtccgaggagggcttcatcgccgcgtgggaggacgtggcg
ccctacatcgagatggtcgacgcccagtccctcaagcgaggggggccgcggatgagcttc
ttcgaggtcctcaccgtcatggcgctggccgccttcgccgaccaccccgtcgacgtcgcc
gtcatcgaggtcggtctgggaggcacgtgggactccacgaacgtcgtcgactccgaggtc
gaggtcatcacccccgtcgggcgggaccacggccggtggctcggggagtccctcgaggag
gtcgcggccaacaaggccggcatcatcaaggacggtgccactctcgtcaccgcccaccag
ccccccgaggtcgagggggtcatcgccgcggctgccgccgagcacggggtggtgtggcgc
cgcgagctcgatccgcaggaggacccgcaggctccgggggccggggtgctgcgggtggtc
gaccgtactcgtgcggtgggcgggcagatggtcaccctggccacggccgccgctgtctac
gaggacgtcttcgtgccccttcacgggcagtaccaggcgcacaacgcgcttctggccctg
gctgccgccgaggcggtcttcggcggcagggcgctgccgcccctggtcgtcgagaacggc
ttcgcctcggtgaccagcccgggccggctcgaggtgctgcgctcatcgcccaccgtcctg
ctcgacgccgcccacaacccccacggcatggaggcgctcgtgcccgcggtcgaggagacc
ttcgggctgcgccacctcgtggtcgtcctgggcgtcatggccgacaaggacgtcgagggg
atcctgtcggtcctcgagcccgcctgcgaggcggtcgtgtgcgtgcccatcgactccccg
cgcgcgatcgaccccgaggacctggctgtccaggcgcgggaggtcttcggcgaggaccgt
gtcgtgctcgcccagagcctggtcgagggtgtggaccgggccgtgtccctggctgagggc
ttcgacgcgccgatgccggccacaggggttctcatcgtcggctcggtcctcctggccgcc
gaggcccgagcactgttctcgcgccggtga
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