Aeromonas hydrophila ML09-119: AHML_16290
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Entry
AHML_16290 CDS
T02683
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ahy
Aeromonas hydrophila ML09-119
Pathway
ahy00260
Glycine, serine and threonine metabolism
ahy00261
Monobactam biosynthesis
ahy00270
Cysteine and methionine metabolism
ahy00300
Lysine biosynthesis
ahy01100
Metabolic pathways
ahy01110
Biosynthesis of secondary metabolites
ahy01120
Microbial metabolism in diverse environments
ahy01230
Biosynthesis of amino acids
Module
ahy_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ahy_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
ahy_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ahy00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
AHML_16290 (thrA)
00270 Cysteine and methionine metabolism
AHML_16290 (thrA)
00300 Lysine biosynthesis
AHML_16290 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
AHML_16290 (thrA)
Enzymes [BR:
ahy01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
AHML_16290 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
AHML_16290 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AGM45026
LinkDB
All DBs
Position
complement(3689907..3692366)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADAERFLRVADIAVNTHGQSQVALVLSAPAKVTNHLVALVEQTSRGMDA
SSTLFEINGIFSRLLAGLKAAYPALDDKALQARLTSELDQVERLMQGIRLLGLCPDNVQA
RILSRGENLSIAFMHELLRVRGLELDIIVPEQLLVTDGGYLEAHVDIEASRLRFAAKGLR
SDCLYLMPGFTGGSDKGETVLLGRNGSDYSAAVLAACVDAECCEIWTDVEGCYNCDPRLV
PDAYLLKTLSYKEAMELSYFGAKVLHPKTIAPVAQFHIPCLIKNSFNPQGPGTLIGVEQG
DDDLKVKAISDLSGMCMFNVSGPGMKGMVGMAGRIFSAVSRAGVSIVLITQSSSEYSVSF
CIHSYDCDKTRKVLEREFELEFKNQLLDPLEIMQDLAIISLIGDGMRTSKGMAARFFTSL
AQASINIVAIAQGSSERSISAVVRDRKVAEAIKACHQNFFGSQQFIDLFVVGVGGVGAAL
VDQIARQQPVLAEQGTGLRVVGIANSRQMAVNKDGLNLANWREQLVEARDSFSLEAVQKL
VEESHLINPVIVDCTSSEAIAVQYADFLAAGFHVVTPNKKANTGSLDYYKALRRTARQTR
RKFLYETNVGAGLPVIENLQNLIKAGDKLRAFDGVLSGSLSFIFGKLDEGMAFSDATKIA
RSNGFTEPDPRDDLNGMDVARKLLILAREAGMALELSDVEVEQALPPGFDVSGDVEAFMA
RLPEADGWFRDQFAAAQAQGKVLRYVGSIEGGKCKVAIKAVGADEPLFKVKDGENALAFF
STYYQPIPLVLRGYGAGTEVTAAGVFADVLRTQNWKQEL
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgagagtgttgaagtttggcgggtcgtcactggccgatgcagagcgttttttacgggtc
gccgatatcgcggtgaatacccacggccaatcccaggttgccctggtgctgtcggcaccg
gccaaggtgaccaaccacttggtggccctggtggaacagaccagccgcggcatggatgcc
agcagcacattgttcgagatcaacggcatcttctcccgcctgctggccggcttgaaggca
gcctatccggcgctggatgacaaggcgttgcaggctcgtctgaccagcgaactggatcag
gtggagcgactgatgcagggcatccgcctgctgggactctgcccggacaacgtgcaggcc
cgcatcttgagtcggggcgagaacctctccatcgccttcatgcacgagctgctgcgagtg
cgcggcctcgagctggacatcatagtgccggagcagctgctggtgaccgacggcggctac
ctcgaagcgcacgtcgacatcgaagcctcccgcctgcgcttcgccgccaagggcctgcgc
tccgattgcctctacctgatgccgggcttcaccggtggcagcgacaagggggagacagtg
ctgctgggccgtaatgggtcggattactccgccgccgtgctggccgcctgtgtcgatgcc
gagtgctgcgagatctggaccgacgtcgagggctgctacaactgcgacccgcgcctggtg
ccggacgcttacttactgaaaaccctctcctacaaggaggcgatggagctctcctacttc
ggtgccaaggtactgcacccgaaaaccatcgcgccggtggcccagttccacattccttgc
ctcatcaagaacagcttcaacccgcaggggccggggacgcttatcggcgtcgagcagggg
gatgatgacctcaaagtgaaggccatctcggatctctccggcatgtgcatgttcaacgtc
tccggccccggcatgaaggggatggtgggcatggccggccgcatcttctccgccgtctcc
cgcgccggggtcagcatcgtcctcatcacccaatcctcctccgagtacagcgtcagcttc
tgtatccacagctatgactgcgacaagacccgcaaggtgctggagcgcgagttcgagctg
gagttcaagaaccagctgctggatccgctggagatcatgcaggatctggcgatcatctcc
ctcatcggtgacggcatgcgcacttccaaggggatggcggcccgcttcttcacctcgctg
gcacaagcctccatcaacatcgtcgccatcgcccagggttcgagcgagcgctccatctct
gcggtagtgcgggatcgcaaggtggcggaagccatcaaggcctgccaccagaacttcttc
ggcagccagcagttcatcgatttgttcgtggtcggcgtcggtggtgtcggtgcagccctg
gtggatcagatcgcccgccagcagccggtattggccgagcagggcaccggcttgcgggtg
gtgggcatcgccaacagccgccagatggcggtcaacaaggatgggctgaatctcgccaac
tggcgtgaacagctggtggaagcccgtgacagcttcagcttggaagcggtgcaaaagctg
gtagaagagagccacctcatcaacccggtgatcgtggattgcacctccagcgaggccatt
gccgtccagtacgccgacttcctcgcagccggtttccacgtggtcaccccgaacaagaag
gccaacaccgggtcgctggattactacaaggcgctgcgccgcaccgcccgtcagacccgc
cgcaagttcctgtacgaaaccaacgtgggcgccggcctgccggtcatcgagaacctgcag
aacctgatcaaggctggcgacaagctgcgcgccttcgacggcgtgctgtctggttcgctc
tcctttatcttcggcaagttggacgaagggatggccttctccgatgccaccaagattgcc
cgcagcaacggctttaccgagccggatccgcgcgacgatctcaacggcatggatgtggcg
cgcaagctgctcattctggctcgtgaagctggcatggcgctggagctgtccgatgtcgaa
gtggagcaggcgctgccgccgggctttgatgtgagcggcgacgtggaagcctttatggcc
cgcctgccggaggctgacggctggttccgcgaccagttcgctgcagcgcaagctcagggc
aaggtgctgcgctacgtgggttccatcgagggtggcaagtgcaaggtcgccatcaaggcg
gtcggcgccgacgagccgctgttcaaggtcaaagatggggagaacgcgctcgccttcttc
tctacctactaccagccgatcccgctggtgctgcgcggctatggcgccggtaccgaagtg
accgctgcgggcgtctttgccgacgtgctgcgcacccagaactggaagcaggagttgtaa
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