Actinoplanes ianthinogenes: Aiant_23660
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Entry
Aiant_23660 CDS
T07429
Symbol
murF_1
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aih
Actinoplanes ianthinogenes
Pathway
aih00300
Lysine biosynthesis
aih00550
Peptidoglycan biosynthesis
aih01100
Metabolic pathways
aih01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aih00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Aiant_23660 (murF_1)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Aiant_23660 (murF_1)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Aiant_23660 (murF_1)
Enzymes [BR:
aih01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Aiant_23660 (murF_1)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BCJ41709
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Position
2521369..2522748
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AA seq
459 aa
AA seq
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MLPLTIAEIAAAVGGVIDNADPEAQVTGLCTFDSRTVEQGSLYAALPGARVDGHDFAEQA
IRSGATVVLAARPVGVPAIVVSDVLAAYGRLATAIAERIPGLGVVAVTGSVGKTTTKDLL
GQLLSALGPTTAPPGNRNSESGMPENVSRLTPESRFLVLEMGARHVGDIAYLTSLVRPQV
GIVLNVGSAHLGEFGSRENIAKAKGEIIESLPADGRAVINADDPLVSAMASRTVANVVTF
GLAPEATVRGESIVVDEFGRASFTLQAPQGSARVSLRLHGEHLVSNALAAAAAVLHFTDD
VALVARVLSSAEPVSGGRMAVSEAPDGITVINDAYNASPVSMIAALKTLKTLAKGRRSVA
VLGQMNELGETSSADHAGVGEEVGRIGVDLLVTVGNDDAAQLGETAAQQGINALHVPDRE
SARELLRDTLIPGDVVLLKGSNGVGLMALGSELAAGLKA
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
gtgctgcctttgactattgccgagatcgccgccgccgtaggcggtgtcattgacaacgca
gacccggaggcacaggtaaccggactctgcacgttcgactcccgcacggtggaacagggc
agtctctatgccgctcttcccggcgcacgagtcgacgggcacgacttcgccgagcaggcc
atccgctcaggcgcgacggtcgtcttggcggcccggccggtcggcgtgccggccatcgtc
gtaagcgacgtgctcgcggcttacggccgacttgctaccgccatcgcggaacgcattccg
ggtctcggcgtggtcgccgtgaccggctccgtcggcaagaccacgaccaaggacttgctc
ggccaactcctctccgcgcttggtccgaccaccgccccgcccggcaaccgcaatagcgaa
tccgggatgcccgagaacgtctcgcgcctcacgccggaatcgaggttcctcgtcctggag
atgggcgcccgtcacgtcggcgacatcgcctacctgacgtcgctcgtccggccgcaggtc
ggcatcgtgctcaacgtcggcagcgcccacctgggcgagtttggctcgcgggagaacatc
gccaaggccaagggcgagatcatcgagtccttgccggccgatggcagggcagtgatcaac
gcggacgacccgctcgtctcggcgatggcaagtcggaccgtcgcgaacgtggtcacattc
gggctggccccggaagcgacggtgcggggcgagtcgatcgtggtcgacgaattcgggcgg
gcgtccttcaccttgcaggcaccgcagggctccgcgcgggtgtcgctgcgtctccacggc
gagcacctggtctcgaacgctctggcagcggcggcggctgtcctccacttcaccgatgac
gtggcgctggtcgcgcgagtgctcagctcggccgagccggtctccggcgggcggatggcc
gtgtcggaggcgccggatggaatcacggtcatcaacgacgcctataacgcgagcccggtc
tcgatgatcgccgcgctgaagacgctgaagactctcgccaagggccggcgaagcgtcgcg
gtgctcgggcagatgaacgagcttggcgagacctcttcagccgaccacgcgggcgtcggc
gaggaggtggggcggatcggagttgaccttctcgtcaccgtaggaaacgacgacgcggcc
cagctcggcgagacggctgcgcagcaagggatcaacgctctccatgtgcccgaccgtgag
tcagcgcgcgagctgctccgagacacgctcatcccgggcgacgtcgtccttctcaagggc
tcaaacggtgttggcctgatggcgctcgggtccgagctagctgctggcctcaaggcatag
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