Amycolatopsis japonica: AJAP_27375
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Entry
AJAP_27375 CDS
T03225
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aja
Amycolatopsis japonica
Pathway
aja00300
Lysine biosynthesis
aja00550
Peptidoglycan biosynthesis
aja01100
Metabolic pathways
aja01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aja00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AJAP_27375 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AJAP_27375 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AJAP_27375 (murF)
Enzymes [BR:
aja01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AJAP_27375 (murF)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
NUDIX-like
Motif
Other DBs
NCBI-ProteinID:
AIG78321
UniProt:
A0A075V0W0
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Position
complement(5857682..5859208)
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AA seq
508 aa
AA seq
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MIVLSLAEIAAIVGGRLHRTDGTAEVTGSVEFDTREVTPGGLFIALPGAKVDGHDFAARA
VESGAVAVLAAREVDAPAVIVPPLAAGEGHERAFALVSDKDGAGAAVLAALAKLARHVIR
KLAGDHLTVVGVTGSAGKTSTKDIIAQLLEPLGPTVAPPGSFNNELGHPWTALRADDSTR
QLVLELSARGPGHIAELAAIAPPRIGVVLNVGTAHVGEFGSREGIAKGKGELVEALPSAE
DGGVAVLNLDDPYVAAMASRTKARVVFVGESESAQVRAVDITLDDEARASFRLVTPDGEA
PVKLPLYGEHQVGNALSAAAVALEMGSTVEEVAARLSSLERRSERRMEVTTRADGVTVLN
DSFNASPESMRAALKALASMSANRRSWAVLGVMGDLGENSVAAHDGIGRLVVRLNIDKLV
VIGQAAAATHQGAQHEGSWGEESVLVPDVDAAIALLHDQLRAGDVVLVKASKAAALWRVA
DAVLAAPATESPVVAPSPSHERSNGGDA
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgtgctcagcctggccgagatcgccgccatcgtcggcgggcggctgcatcggacc
gacgggaccgccgaggtcaccggaagcgtcgaattcgacacccgtgaggtcacccccgga
ggtctgttcatcgcgctgcccggcgcgaaggtcgacggccacgacttcgccgcgcgggcg
gtcgagtcgggcgccgtcgcggtgctcgcggcccgcgaggtcgacgcaccggccgtgatc
gtgccgccgctggcggccggcgaggggcacgagcgggcgttcgcgctggtctcggacaag
gacggggcgggtgccgcggtgctggccgcgctcgccaagctcgcccggcacgtcatccgg
aaactcgcgggtgaccacttgaccgtcgtcggggtcaccggttcggcgggcaagacctcc
accaaggacatcatcgcccagctgctggagccgctcggcccgacggtggcgccgccgggc
tcgttcaacaacgagctgggccacccctggacggcgctgcgggccgacgactcgacgcgg
cagctagtgctggagctctccgcccgcgggcccggccacatcgccgaactggcggccatc
gcgccgccgcggatcggggtcgtgctcaacgtcggcaccgcgcacgtcggcgagttcggc
tcgcgcgagggcatcgccaagggcaagggcgagctcgtggaggcactgccgagcgccgag
gacggcggtgtcgcggtcctgaacctcgacgacccgtacgtcgcggccatggcgagccgg
acgaaggcccgggtcgtgttcgtcggcgagagcgagtccgcgcaggtccgcgccgtcgac
atcaccctcgacgacgaggcgcgcgcgtcgttccgcctggtcaccccggacggcgaggcg
ccggtgaagctgccgctctacggcgagcaccaggtcggcaacgcgctcagcgcggccgct
gtggccctggagatgggctcgacggtcgaggaggtcgcggcccgcctgtcgagcctggag
cggcgctccgagcgccgtatggaggtcaccacccgcgccgacggtgtcacggtcctcaac
gactccttcaacgccagccccgagtcgatgcgggccgcgctcaaggcgctcgcgtcgatg
agcgcgaaccgccgttcctgggccgtgctcggcgtgatgggcgacctcggcgagaactcg
gtcgccgcgcacgacggcatcggcaggctcgtcgtccggctcaacatcgacaagctcgtg
gtcatcggccaggccgccgcggccacgcatcagggcgcccagcacgagggttcctggggc
gaggagtcggtactggtacccgacgtcgacgccgccatcgccctgctgcatgatcagctc
cgcgcgggagacgtggtgctggtgaaggcgtccaaggccgccgccctgtggcgggtggcc
gacgccgtgctcgccgctcccgcaaccgaatcccctgtagtagccccttccccctctcac
gaacgctcgaacggtggtgacgcgtga
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