Anneissia japonica (feather star): 117125493 Help Entry 117125493         CDS       T08613                                  Name (RefSeq) ryanodine receptor 2-like   KO K04962   ryanodine receptor 2 Organism ajc  Anneissia japonica (feather star) Brite KEGG Orthology (KO) [BR:ajc00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:ajc04040]     117125493    04990 Domain-containing proteins not elsewhere classified [BR:ajc04990]     117125493 Ion channels [BR:ajc04040]  Voltage-gated cation channels   Ryanodine receptor    117125493 Domain-containing proteins not elsewhere classified [BR:ajc04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    117125493 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR SPRY MIR Ins145_P3_rec RIH_assoc RR_TM4-6 EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_5 EF-hand_6 SPARC_Ca_bdg EF-hand_FSTL1 Motif Other DBs NCBI-GeneID:  117125493 NCBI-ProteinID:  XP_033127881 LinkDB All DBs Position Unknown AA seq 4840 aa AA seqDB search MAATASSGGTTGESTEDETAFLRTGDQLCLMCSSQSKVSTDTMILAAEVFGNRVCHLEKR AGQDMPTDLTTCVFYLEQALSVKALQEMVTADAMETGGQAGHKTLLYGHAVLLTHAVSSM YLSCLPTSSSTDKLAFDVGLQETAQGESCWWTIHPASKQRSEGEKVRVGDDLILVSVSSE RYLHISTPKGNCPSRVQASFQKALWTALPVSSGSVKSRAMGFVNGLDVLRFSHGHINEFL TVPAAGCKDDSRISEVAYECGDVSKYARSLWAIELLSKRWNGSYLSWGQPCRIKHITSGK YLAINEEKDVFIAPKQNADHISSVFCLRQSKDDQEEFDNKGEQGMRQAEIKYGDSTVFIQ HYSTQLWLTYLVSQTGVSAHAAERKVVVHSEGHMDDGFSVVRARQEESRSAGIIRKSGTV FHSFISALDSLQDVGDDRAVWDSFSLEDLTKCLEDLITYFEEPEDNIAYEEKQKKLKALR NRQDLFYEEGMVSLVLDTIDKLSMYKSGRDFGAIAGASAGESWEVILNYLYKLIAAMIRH NHSNCSLFAQAAKLDWLVSRLENQQASSGVLEVLHCVLIGSPEALHIIKEQHIKSMISQL EKHGRDHKVLDVLSALCVGNGVAVRANQNLICENLLPARDLLLQTALVDEIVSLRPNIFI GLSTGAAIYKKWYYELAIDEVESVNSRPPHIRIGWATTDGFRPYPRGGEGWGSNGVGDDL GSFGFDGLNIWTGGMSKPAHWNNCRLLSKGDIVGCCFDLSIPRVLFHVNGNPIKASFEGF NLRGMFYPVISVSAKVSVRFLFGGKNGRFKFTAPKGFAAICESILPKQKLRIEPCFGFGK LSENILSGPEASRGYTTFVPKPVDTSQILLPGYVEVLRDNLAENIHERWCMNKIDSGWTW GKVRDDIKKIHPSIAPFDTLSEEERNSDITMAFETLRTLLALHYHLGIDEDASRKNLHKL RLPLNYIMPNGYKPAPYNLSSIILNPMLERLVDLLAENSHNVWAKERIEQGWTYGLSEDG AFKRNPLLIPYSELDDEAKKLNWSSAAETVKSIIAFGYTLEPPPSEVFDGGFRGLVQEMA DTTQKCRVFRSEKSYAVTSGKWYYEFEVLTAGRMNVGWARPSIDPGVSLGVDGKAFVFDG FLARKWNQGSEHFGKIWKVGDVIGCLLDLVNNSISFTLNGELMSDLSGSEMAYRDIEVEE GFIPVWNMAPGEEAKLHFGQDLNALQYFTVCGLQEGYEPFCVRIGYAFGNMKKDLPLWYS KSQPVFASITDDHEKLRVTTIPASVEGPPCLKVSYKNSGSLEHPPCEFIRLSMPIECQDS SSGELAVSIPVPSLQRRDKKGWMNQASGSFESGGTDYSYDEGKVNGYHSNTLESDSDLDI VPINRLATGFKRKKPTKPDSDSDTGQRSNGTDIVKEKKKMSTLGFSRKIPFVRASSTEAD ASSKDEGLTVKSRRSKFMKSASEDSTVERRNRSKSPSGSKSKRSKSPDDSLTDLPSPPSI SSTSTDIPLRPKLSKINSMGSSFDRSVEILSDISEVDSIDMANAKRYSFAVRILPGQEPG DVHVGWVSPNFHFMKDKFNALDTREVRVNTLNEIGVVQESVKRRDCYMIAVGSFLDVGSG DGRPIATGVTVGCAIDVSSGELSFTINGRDIGSKFQVESTTRLYPAVVVAPSTNEMLQFE LGRSKNCLPLSASWFRGEAGNTIGQCPSRVKVQAMQSFSWARVPNKVPDIESKKVSDSSG WVVSLSDPVSWLAVHIPEENRSLDILELIEHDNLLEFHNKTLQLYRAVCSHGNHSVAHAL CKHVDQNQLMYCIQCSYMCGTLRMGYHDLLISVHLETLCSARKMTQDEFIIPLGVNCGKV YECDADNEPRSHSIKRALSTTQNTSIRPSQLMTDDNDTPVKSTETSPPPFNRLLLKGHII QCLTESVSHGVSQSRDPIGGSYNNLFVPLLRLCDCLLVMGEIDDEDLKQLLILIDPTTFD DTYVSGVSTHIGLLQMHLDEPVKLEMCYLLQHLCDSQLRHRVEAIVNFSDDFVAECQADQ ERRFQEVSSADLPPIVTAKKTKEFRSTPIEQMRMLLSFKTEEELSICPCREDLRDVLTAF HENLISHCGVHEQTENDDKDISWIGRFLQWLKGSKKDTEEKEDFMKKFSGDSLSFLISGT MVNWAQEQHIEDSVLIREMFRLMYRQYDGVGELCRALYKTYVVSSDQKEDIINLLTSLGH IRSLLTIQMGQMEEEALIKHLWEMTDNKVFYQHPDLMRALCVHETVMNVMVNVLEKHQTS IQLSSGEVNPSNQSNQLSGMASTAKSQKDMNFNHEVIAACSRFLSYFCRIAMDCQMALFG GLDYLLDISYIGLSLPSLRGSCPLDVAAASLMDNNELALALRGQHLEKVIKYLSKCGMKN NARMMSLGKENIGWDPLDGERYLDFMKHAVWVNGETVEENANLVVRLLIRHPECLGPALR SEGKGLLAAMKDAIEMSESAEEGFPPGMQSLPKIITEGGEEPVPEDEDDVDMGGAILTFY AVLIDLLGRCAPDKQVLSHGKSESQRMRAILRSLVALDDLEGVLSLKFNLPSPSKVYEKK DDTLGKPLGADLKGLTPSHKEAMLLFMERVYGISDQEMFFRLLEVGFLPDLRAAMAMDTP NTHDHDMALALNRYLCNSVLPLLTRHAHMFENAGHNISLLDSTLNTVYRLSKCRSLTKGQ RDTIADFLVALTKSLRPSMMQRLLKKLTVDVPVLVEHTYVALKILTLHYERCIDYYGSHG GWGSYGAANDEEKRLTMMLFTGLFDALADREYDAELFNKALPCLTAIGRALPPDYSMAYH DESLIRESNIDADGVYQPCPVDTSKIHLNENLLSFRDRFAEFLHDTWSLEKFEHGWTFDE VTNPMMQHHAMLRPYRNLTTKEKDQYRDAIKESLKAIHAWGWTIERSSSDQNKQLRRRLS KTSLGVVESPHGYNPRPIDMSNITLTRDMQNMAERLAENAHDLWAKKTKTTLEASGGDCH PLLVPYDILTDAEKKKDRQMTQALLKFLQVNGYRLQSDTSNEDERNGSSDAQDRMSHVNN TIEKRFAYNLLEKLIHYVDKAQANLRPGFKKREMEERSYKFFVRVVLPLIERYFEAYCCY FVSSPSSLQSSRFGSASHREKEMVASLFCKLSHLVRQKINLFQAQDLNCTVCCLEVVATA IDGRSITKHGSGSVKNALLVFFCNAADDLDCTQVNVKSGYFSHVKPPDFKEGLIMKYVAG VLLPVLTSLFKHVGNFKFGEELLLDQVQLACYKIIKTLFALGAAKQFSADCEKEKKCIES HRPAIGELLAAIAGSFPVAFLEPQLNKNNRNSVLGQQAMRAIAKGEAELEGINSSSYGIP TLEAMIREIDEMAESGAKYYEAPHVIEVILPTLCSYLPFWWQEGPDSINRRQGNYWTMVS SRNMNTTLGNVLTLIKNNLGSENAPWMSRIAAISLPILSNADESMLSSHFLPVAEVLRRR AEIVFQSEEDLKKNFPGGGTEMEEAELELLEHYGLLVRDVFAFYPLLIKFVDHHRSKWLQ SSSVCAEMLYKHVADIFNWWAQSSNFKREEQNYIAQNEPQSNAGRDRDNKSYSSSRIVAC IKRLLPIGMNLYGAMEQELVQEAKQKLLERDTEKDVREFLLHTLRQQEKKVDDDEDSSDL EPCRNSSSTSSHSPSHGPQVSSWQRRLYSKMSSSNLSNVSLPQEEVVQRVLSMAIVLHRL HITEHPPVSKKSAWRRLISAQRRRAIMACFRMIPLRALPRHRAINFFLRIYKEKWLGVEE SARHLLIDDITKEDLEELPEEEIKDPLQQLVMMFCRAASLHQNAVEDDLYLSYAEIMSKS CSGDDEDDDDDDEEPGVSFQEQEMAKQKLLSEQGRLADRQVSEMVLLNISASQGKASSMV KDTLNLGISLLRGGNVTVQEKMLAHLQDKMDVGFFTSLAGIMESSSVLDLEAYERYNKAK GLGGGFGDSADENGAIAGEQALHDAPITCALFRFLQLLCEGHNGDFQNYLRTQTGNHTTV NIIIYTVDYLLRLQESISDFYWHYSRKEVVDVQGRENFSRAIKVAKQVFRTLTEYIQGPC SGNQLALAHSRLWDAIGGFLHVFAHLQKKLSQDASQLELLRELLNLQKEMVVLLLSMLEG NVMNGTIGKQMVDALVDSSQNVEMLLKFFDMFLKLKDLEAADAFAEYDINGDGWISQKEF QKAMESQKMYTSSEISYLLKCADTNNDGKIDFKEFTERFHGPAKDIGFNLAVLLTNLSEH MPSDTRLQRFMEVAESVLTHFEPCLGRIEIMGSSRRIERVYFEIKDSYKEQWEKPQIKES KRQFLHEVVNEGGEKEKLEDFVNFCEETIFEMQHAASISDDSEGLTESLGQLFTRGKESQ GFVGSVFRAVSPSNLISQVRETWQNSEYDVKKLRTITLSGLIKNFFKLLFFLFCKLGSLG IALTCYIFRCIVGNKTGDAPVRINVPLSVTDRLKVPTLARQIAGTTSAPSPTANANANLS AFGIDISRRKESESGKTLLHFRGKKRKAVSAQSFDFGKTDASPITLDATDSPNLQNGHGT QVGNGLGRRESTVFPSYFMAAEQGQNQDEEEEEEEVQPGLSNIKQTVLSFFARNFYNLKT VLLVLAFTINFLLLWFRATTSMEDVPDVPVDIAEPDINTTLGNDTSGSLEEEGDLPEVIE IAEGYYYINHILQTLCIIHTLASLSMLLAYCALKMPLAIFKREKEVARKLEFDGMWIVEQ PSTDDIKGHWDKLAISAPSFPENYWDKFVKRKVLKKYADSVGEDKLRSMLGLEEDKPSEE EGLLSSLLTAVDFKYQIWKCGVICTDNVSTYKSTFIKFNR NT seq 14523 nt NT seq  +upstreamnt  +downstreamnt atggcagccacagcgtctagtggtgggaccactggggaaagtactgaagatgagaccgcg tttttaagaacaggagaccagctatgtttgatgtgctcgtcccagagcaaggtgtcaacc gacaccatgatcctggcagccgaggtcttcggtaatcgtgtatgtcacttggagaagagg gctggtcaggatatgccaaccgatttgacaacatgtgtattttacttagagcaggccctc tcagtgaaagctctccaagagatggtaacagctgatgccatggaaacgggcgggcaagca ggtcacaagacattattgtatgggcatgcagtcctgctgacgcatgctgtcagttccatg tatttatcatgcttgccaacaagttcatcaacggataagttagcctttgatgtcggtctt caagaaacagctcaaggcgaatcatgttggtggacgattcatcctgcatctaagcagagg tcagagggtgagaaggtcagagtaggcgatgacttgatcctggttagcgtatcatcagaa cgatatcttcacatatcaacacccaaaggaaactgcccatcaagagtacaggcatcattc caaaaggcactatggacggcattaccggtcagctccgggtcagtaaaatcacgagccatg gggtttgtcaatggcctggatgtgctgcgcttctctcatgggcacatcaatgaattcctg acagtacctgcagctggatgtaaagatgacagccgcatcagcgaagtggcttatgaatgc ggagacgtctctaaatatgctcgatcattatgggccatcgagttgttatccaaacgatgg aatggaagctacctttcttggggacagccttgtaggattaagcacataacgtcaggaaag tatcttgcaattaatgaagaaaaagatgtgtttattgcaccaaagcagaatgctgaccat attagcagtgtgttttgcctcaggcaatcaaaggatgaccaagaggagtttgacaacaaa ggagaacagggaatgcgtcaggctgaaatcaagtatggagactccactgtgttcatacaa cactactccacgcaactttggctcacttatctggtttctcagacaggagtttctgcacac gctgctgagagaaaggtggttgtacattctgagggtcacatggatgacggtttctcggtt gtgagagctcgacaagaggaatcgcgatctgcaggtatcattaggaagagtggaacagtc ttccattctttcatcagcgccctcgattcattacaagatgttggtgacgacagagcagtg tgggatagcttctcattggaagatcttactaaatgtttagaagaccttattacatatttt gaagaacctgaagataatatagcttatgaagaaaaacagaagaaattgaaagcattgcgg aatcgacaggatttattttatgaggagggtatggtatcattagttctggataccattgat aaactaagtatgtacaagagcggacgggattttggtgctatagccggggcaagtgctgga gaatcctgggaggtgattcttaactacctctataaattaatagctgcaatgatacgccat aaccatagtaactgttccttatttgctcaggcggctaaactcgactggttggtcagtaga cttgaaaatcaacaagcttctagtggtgttttagaagtgttacactgtgtgctaattgga agtccagaggctcttcacatcatcaaagaacagcatatcaagtcgatgatatcacaactt gaaaaacacggtcgggatcacaaggttctcgacgtactttccgcgttatgtgtcggcaat ggtgtcgctgtccgcgcaaaccaaaacctgatctgtgaaaatttactccctgcccgagat ttgcttttacagacagcattagttgatgaaattgttagtttaagacccaatatatttatt gggttaagtacgggtgctgcaatatataaaaaatggtactatgaattagcgatagatgag gtggaaagtgtcaactctaggccacctcatatccgtattggctgggctactacggatggg ttcaggccctatcctagaggaggtgaaggctggggaagcaatggtgttggtgatgatcta ggatcttttggatttgatggccttaatatctggactggtggtatgtcaaaaccagcacat tggaataattgtcgtctgcttagtaaaggtgacattgtaggctgctgttttgacctgagt attccaagagtgcttttccatgtcaacggcaacccaatcaaagcttcgtttgaaggcttt aacttgcgaggcatgttctacccagttatatcagtatcagctaaagtcagtgtgaggttt ttatttggcgggaagaatggccgttttaaattcacagcgccaaaaggtttcgccgctatc tgtgagtccatccttcctaagcagaaactacgcattgaaccatgctttggttttggcaag ctgtccgagaatattttatccggtcctgaggcatctcgtgggtacaccacatttgtaccc aaaccagtagatacctctcagattctgctaccaggctatgtagaagttttgcgagataac ttggctgagaacatccatgaaagatggtgcatgaataagatagacagtggatggacgtgg gggaaggttcgagacgatataaagaaaattcacccatcaatagcgccatttgatactctc tctgaggaggagagaaactcagacattactatggctttcgaaacactaaggactttatta gctcttcactatcacctcggtattgacgaagacgcatctagaaagaatttgcacaagctc agattgccattaaattacatcatgccaaatggatacaagcccgccccctataatctgtca tccatcattctcaatccgatgctggagcgactggttgatctgctggcagagaactcgcac aacgtatgggcaaaggagaggattgaacagggttggacgtacggcttatcagaagacggt gcgttcaaaaggaacccactgctgatcccttacagtgaactggacgatgaggctaagaag ttgaactggtcgtctgctgctgagactgtcaaatccatcatcgcctttggttacacctta gaaccaccaccatctgaggttttcgacggtggattccgaggtctagtacaggaaatggca gacacaacacagaaatgtagggtgttccgctcagagaaaagctatgcggtaacttcagga aaatggtattatgagtttgaggttctaacagcaggcagaatgaatgtaggttgggcacga ccttccattgatcctggtgtcagccttggcgtggacggcaaagcttttgtctttgatgga tttcttgctcgcaaatggaaccaaggctctgaacattttggtaagatctggaaagtaggc gatgtgattggctgcctacttgaccttgttaacaattcaataagttttactttgaatgga gagcttatgagtgacttatcaggatcagaaatggcatacagagatattgaagtagaggaa ggttttataccggtttggaacatggcacctggcgaagaagcaaaattgcattttggacag gatttaaatgcattgcagtattttactgtgtgtggattgcaagagggatatgaacctttc tgtgtaaggattggttatgcttttgggaatatgaagaaagatttgcctctctggtactca aagagccaacctgtgtttgcctcaatcacagacgatcatgagaaacttcgagtcacaaca ataccagcaagtgttgaaggcccaccttgtttgaaagtgtcttataagaattctggttca ctggagcatccaccttgtgaattcatccgtctgagcatgcccattgaatgccaagattcc tcatctggagagttggcggtctccattccagtcccatcattacaacgtagagacaagaag ggctggatgaatcaggctagtggtagctttgaatctggtggcactgattattcatatgat gaaggaaaagtgaatggttaccatagtaacactcttgaaagtgattcagatcttgatatt gtaccaattaatcgtcttgcaacaggatttaaaagaaaaaaaccaacaaaaccagatagt gactctgataccggccaaaggtcaaatggtacagacatcgtgaaggaaaaaaagaaaatg tccactctaggcttcagccgtaagatcccatttgtcagagcaagttctaccgaagcagat gcctcctcaaaagatgaaggtctgacagttaagagtaggcgtagtaagtttatgaaaagc gcaagtgaggattctacggttgagcgcagaaatcgaagtaaatctccatcaggaagcaaa tcaaaacgctccaaaagcccagatgattctctaacggatctgccgagtccccccagcatt agttccaccagtacggacataccacttcgaccaaagctttccaaaatcaactctatggga agtagttttgatcgatctgtggagatattatcggatattagtgaagtggactcaatcgat atggctaatgccaaacgatattcctttgcggtacggattctacctggtcaggaaccaggt gatgtccatgtcggatgggtgagcccgaacttccattttatgaaagataaattcaacgct cttgacacaagggaagtacgagtgaacacattaaatgaaattggagtagtacaagaaagt gtcaagcgtcgtgattgctatatgattgctgtaggcagcttcttagatgttggttctggt gatggcaggcccatagcaactggtgtgactgtgggatgtgcaattgatgtcagtagtgga gagctttcatttactatcaatggcagggatattggatccaagtttcaggttgaatctacc accagactatatccagccgttgtcgttgcccctagcaccaatgaaatgctgcaatttgaa ttaggaaggtcaaagaactgccttcctttgtctgctagctggtttcgtggcgaggctggt aacacgatcggccaatgcccttcgagggtcaaggtgcaagcgatgcagtctttctcctgg gcgcgtgttcctaacaaggtccctgacatcgaatctaagaaagtgtcagacagctcaggc tgggtagtttccttaagtgatccagtgtcctggttggctgttcatattccggaggaaaat cgtagtttagacattctagagttaattgaacatgacaatcttttagaattccacaacaag acattacagctatatcgggctgtttgttcccatgggaaccactctgttgcacatgctcta tgcaaacatgtagaccagaaccagctcatgtactgtatacagtgctcttatatgtgtggg acattacggatgggctaccatgacttgcttatctctgttcatctggaaacgctatgcagt gcaaggaaaatgacccaggatgagtttattatccctttgggggttaactgtggcaaagtt tatgagtgtgatgcggataatgagccacgaagccactctatcaagagggcgctaagtaca actcagaacacctccatcagaccttcacaactgatgacggatgataatgatacacctgta aagagcacagagaccagcccaccacctttcaaccgattgttgctgaagggacacatcatt cagtgcctcaccgagtctgtatctcatggggtttcccaatctagggatccgattggtgga agttacaataatttatttgtaccattgctaagattatgtgattgtttgcttgtcatggga gagattgatgatgaagatttaaaacagctgcttatccttatcgacccaacaacatttgat gatacatatgtttcaggtgtcagcacccatattggtcttcttcaaatgcaccttgacgaa ccagttaagctagagatgtgttacctattgcaacatttgtgtgacagtcagttacggcac cgagtcgaagccatcgtcaatttctcggatgattttgtagccgaatgccaagcggaccag gagagaaggttccaagaagtgagttctgcagacttacctcccattgttacagctaagaaa accaaagaattccgatcaacacctattgaacagatgagaatgcttctgagcttcaaaaca gaagaagagcttagcatttgtccatgtcgagaagatctacgcgacgtcttgactgcgttc catgaaaatttgatctcgcattgcggtgtgcatgagcaaactgaaaatgatgacaaagat atctcttggattggtcgtttcctccagtggttaaagggatccaaaaaggacacggaagaa aaagaagacttcatgaaaaagttttcaggagactcgttatccttcctgatctctggaact atggtgaattgggcacaagagcaacacattgaggattcagtccttatccgggaaatgttt cgactgatgtaccggcagtacgatggggtgggagagctttgcagagctttatacaagacg tatgttgttagtagtgaccagaaggaagacatcataaacctgttgacatcgctgggtcac ataaggtcgttacttacgatccaaatggggcaaatggaagaagaagctctcattaagcat ttgtgggagatgactgataacaaagtattctatcagcaccctgacctaatgagggcgctg tgtgttcatgagacggtcatgaacgttatggtcaatgtcctagaaaaacaccagacttct atccagctgagtagtggtgaggtaaacccgtccaatcagagcaaccaactcagtggcatg gccagtacagcaaaatctcagaaggacatgaattttaaccatgaggttatagctgcctgc tccaggttccttagctacttctgccgcatagcaatggattgtcagatggctctctttggg ggcctagactatcttcttgacatcagttatattggactatctttaccctctctgagagga tcatgtcctttggatgttgctgccgcatcattgatggataacaatgaacttgctctggcc ttgcgagggcagcatttagagaaagtgatcaaatatctgtcaaaatgtggcatgaagaat aatgctaggatgatgtcactcggaaaggagaatattggatgggacccgctcgatggagaa cgttaccttgatttcatgaagcatgctgtgtgggtgaatggtgagactgtggaggagaat gctaatttagttgtacgcctacttattcgtcaccctgaatgtcttggtccagcactgaga agtgaaggcaaagggctgctggcagctatgaaagatgcaattgagatgtctgaaagtgct gaagagggattcccacctggaatgcagagcctaccaaagattatcactgaagggggagaa gagccagtacctgaagacgaagatgatgttgacatgggtggagcaatactgacgttttat gctgtattaatcgacttacttggtagatgtgcaccggataaacaagttctcagtcatgga aaatctgaatcgcagagaatgagagccattcttagaagtttggtggcccttgatgatctt gaaggcgtactttcattaaagttcaacttgccgtcaccaagtaaagtctacgagaaaaaa gatgacacactagggaagccactgggagcagacttaaagggattaacacccagccacaag gaagcgatgttgctgttcatggaacgagtgtacggaatcagtgatcaggagatgttcttt agactactagaagtaggcttcctaccagacttaagagctgctatggctatggacacgcct aatacccatgaccatgacatggctcttgccttgaatcgatatctatgcaattcggtgcta ccgttactcacgcgccacgctcacatgtttgagaatgctggccataacatctccctactg gattctacactcaatactgtctatcgtctgtccaaatgtcggtcacttacaaaaggccag cgagatactattgctgattttcttgtggcactgaccaagagtctgcgaccatccatgatg cagcgtctactgaagaaacttactgtagatgtccctgtattagttgaacatacttatgta gctctgaagatcctgaccttacattatgagaggtgcattgactactacggcagtcatgga ggctggggcagttatggtgcagctaacgatgaggaaaaacgcctaacgatgatgctgttc acaggactctttgatgctctagctgatagggagtatgatgcggagttgttcaacaaggcc ctcccgtgtctgactgccattggtagagctcttccacccgattattctatggcctaccac gacgagagcctcatacgagaatcaaacattgatgctgatggcgtttatcaaccatgcccc gtggacacgtctaaaatccatttgaatgaaaatctattatccttccgagatcgatttgca gagtttctacacgacacttggtccctagaaaagtttgagcatggatggacttttgatgaa gttaccaatcctatgatgcaacatcacgccatgctgcgaccataccgcaatctcactaca aaggaaaaagatcagtatagggacgccatcaaagagagtcttaaagccattcatgcttgg ggttggacgatagaacgtagcagctcagaccagaacaaacaactacgaagaagactttcc aagactagcctgggagtagtggagtcaccacatgggtataacccacgcccaattgacatg agcaacatcaccctaacaagagatatgcagaatatggcggagagacttgctgagaatgct catgacctgtgggccaagaagacaaagacgacacttgaagcttctggtggagattgccat ccccttttggtgccgtatgacattcttacggatgcggagaagaagaaagatcgacagatg acacaagccctcttaaaattccttcaagtcaatggatatcgattacaaagcgacacatca aatgaagatgagaggaatggaagcagtgatgcccaggacaggatgtctcatgtcaacaat acgattgaaaaacgctttgcatacaatctgctggaaaagttgatacactatgttgacaag gctcaggcaaacctcagaccaggttttaagaaaagagaaatggaagaaagaagttacaag ttctttgtcagggttgtacttccattgattgagaggtattttgaggcctattgctgttac tttgtgtccagtccaagctcactgcagtcaagtcgctttggaagtgcttcacacagagaa aaagaaatggttgccagtttgttttgcaagttatcacaccttgttcgccagaagataaac ctttttcaagcccaagaccttaactgtacggtgtgctgtttagaggtcgtagcaacagca attgatgggaggtccattaccaaacatggttcaggctctgtgaagaacgccctcctagtt ttcttctgcaatgctgcagacgacctggattgcacccaagttaacgtgaagtccggctac ttcagtcacgtcaagccaccagacttcaaggaggggttgatcatgaagtatgtggctggt gtacttctaccggtgcttactagcctcttcaaacacgttggcaatttcaaattcggggaa gagctactgcttgatcaagtacagcttgcttgctacaaaatcatcaagactttgtttgct ctaggagcagctaagcagttctctgctgactgtgagaaggagaaaaagtgcatagaaagt catcggcctgctattggagaactgttggcagcaattgccggttcgttcccggtggcgttc ctagagcctcagctgaacaaaaacaaccggaattcagtattaggacagcaagcaatgaga gctattgcaaaaggtgaagcggaattagaaggtatcaacagttcttcatatggcattcca acactggaagccatgatccgggaaattgatgagatggcagaatccggagctaaatactat gaggcaccacatgtgattgaggtgatattacccaccttgtgcagctacctaccattctgg tggcaagagggccctgacagcatcaacagaagacagggtaattattggacgatggtgagt tctagaaacatgaacaccacactaggaaatgtgctgaccctcatcaagaacaatctaggc tcagaaaatgcaccttggatgagcaggatagcagccatttcgctacccatcttgagtaat gctgatgagagcatgctaagttcacactttctaccggtggcggaggtgctacgcagacga gccgagatagtattccagagcgaggaggatcttaagaaaaacttcccaggaggtgggaca gagatggaagaagctgagcttgaactgcttgagcattatggtttgttggtgagagatgtt tttgcattctatccgcttctgatcaagtttgttgaccatcacagatcaaaatggcttcag tcttcaagtgtgtgtgctgagatgctttataaacatgttgctgacatcttcaactggtgg gcccagtcatcaaatttcaaacgagaagagcaaaattacatcgctcaaaatgagccacaa agtaatgcaggacgagatcgtgataacaagagctactcatctagcagaattgttgcatgc attaaacgtctcctaccaattggaatgaatctctacggagcaatggagcaagagttggtc caggaagccaaacagaaactactggagcgggatacagagaaagatgttcgtgaattctta ctccacactctgcgtcagcaggagaaaaaggttgatgatgacgaggattcgtcagattta gaaccctgtagaaactcttcatccacttcctctcattcaccttctcatggtccccaggtg tccagttggcagcggcgtctgtattccaagatgtcctctagtaacttgtccaatgtcagt cttcctcaggaagaggttgttcagagggtactcagtatggctatcgttttacacagactt cacatcactgaacatcctccggtatcaaagaaaagtgcatggcgtcgtctgatctctgct cagagacgccgtgccatcatggcctgcttcaggatgatacctctacgtgctcttccaagg catcgtgccatcaactttttcctgagaatctacaaagaaaaatggctgggagttgaagaa tctgcaagacatttgctgattgatgatatcacgaaagaagatctggaggagctgcctgaa gaagaaatcaaagatcctctacagcaattagttatgatgttctgccgggctgctagtcta caccaaaacgctgtagaagatgatctctacttgtcttatgctgagataatgagcaagagt tgcagtggcgatgatgaggatgatgatgatgatgacgaggaaccaggagtctcctttcag gaacaagaaatggcgaaacagaagctgttgtctgaacagggccgactggccgacagacaa gtgtctgagatggtcttgctaaatatcagtgccagtcaaggaaaggcttcctcgatggta aaagacactttaaatcttggtatctctctcttgcgtggaggaaatgtaactgttcaggag aaaatgctagcccacttacaggacaaaatggatgttggattctttacaagtttagcggga atcatggaatcttccagtgttctggatctagaagcctatgaacgttacaacaaggccaaa ggcttaggtggtggatttggagatagtgcagatgaaaatggtgctattgcaggagagcaa gcattgcacgatgcgcccatcacatgtgctttgtttcgattccttcagcttctttgtgaa gggcacaacggcgatttccagaactatctacgtacacagacgggaaaccatacaactgtc aacattattatttatactgtggactatctacttcgacttcaggaatccatcagtgatttt tactggcattattcaagaaaagaagtagttgatgttcaggggcgtgagaacttctcccga gccattaaagttgccaaacaggtgtttagaacactcactgagtacatacagggtccgtgc tctgggaaccagctagccctcgctcacagtcgcttgtgggacgccattggaggattcctt catgtgtttgcacatttacagaaaaagttgtcccaggatgcaagccaactggaactgctg cgtgaactgttgaaccttcaaaaggagatggtggtcttgcttctcagtatgcttgaagga aatgtgatgaatggaacaattggcaaacagatggtagatgctttagtggattcatcacag aatgtggaaatgcttctgaaattttttgatatgttcttgaaactgaaagatttggaagca gctgatgcatttgctgaatatgatatcaatggagatggatggatctctcagaaagaattt caaaaagcaatggaatctcagaaaatgtacacatcgtcggagatatcctatctactgaag tgtgcagacaccaacaatgatggtaaaattgatttcaaagaattcactgaacgtttccat ggtccagcaaaagacatcggtttcaaccttgctgttctgttgaccaacttgtctgagcac atgccgagtgacactcgactgcagcggttcatggaggtcgcagagagtgttctcacgcac ttcgagccttgcttaggacgtattgaaattatgggcagtagtaggcgcatagagcgagtc tattttgaaattaaggattcgtacaaagaacaatgggagaaacctcaaatcaaggaatca aaacgtcaattcttgcatgaagtagtgaatgaaggtggtgaaaaagagaaactggaagac ttcgtcaacttctgcgaagagactatctttgagatgcaacatgcagcaagtattagtgat gatagtgaaggcttgaccgaaagcctcggacagctgttcacgagaggcaaagagtcacag ggttttgtgggctctgtgttccgtgctgtatcaccttccaacttgatatcgcaagtaaga gaaacatggcagaattctgagtatgacgtcaagaagctacgaactatcacattgtcgggt cttatcaagaatttcttcaaactcctcttcttcttgttctgtaaactaggctccttagga attgcactcacttgctatatatttaggtgcattgttggtaataaaactggagatgcacct gttcggattaatgttcctctgtcagtaactgaccggttgaaggttccaaccttagcaagg cagattgctggcacaacttcagcgccttcacctactgctaatgcaaatgctaatttgtca gcatttggtatagatatttcacgacgtaaggaaagtgaatctggaaagacacttttacat ttccgtggcaagaaacgcaaggctgtgtctgctcagagctttgattttggtaaaacagat gcatcccctatcaccctagatgcaaccgattcaccaaacttacagaatggtcatggaacc caagttggaaatggattaggtaggagagagagtacagtctttccaagttattttatggca gcagagcaaggccagaatcaagatgaagaagaagaagaggaagaagtgcaaccaggattg tctaacattaaacaaactgttctgagtttttttgcacgaaacttctacaatctaaagact gttctgctggtattggcattcacaatcaacttccttctgttatggtttagggctaccacc agtatggaagacgttccagatgtaccagttgatattgctgagcccgatataaacaccaca cttggcaacgacacatcaggaagccttgaggaggagggcgacctaccagaggtcattgag atagcggagggatattactatataaatcatatacttcaaactctatgtataatacatacc ctagcatcactctcaatgttgcttgcatattgtgcattgaagatgcctcttgctattttc aaaagagagaaggaagttgcaaggaagctggaatttgatggaatgtggatagtggaacag ccatccacagatgacatcaaagggcactgggacaaacttgcaattagtgctccgtcattc cctgaaaactactgggataaatttgtcaagagaaaggtgttgaagaaatatgcagacagt gtcggcgaagataaattacgttcaatgctaggccttgaggaagacaaaccatcagaagag gaagggcttttatcctcactattaacagctgtggacttcaaataccaaatatggaaatgt ggtgtcatctgcacagacaatgtaagtacatacaaaagcacatttattaaattcaataga tga

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