KEGG   Artibeus jamaicensis (Jamaican fruit-eating bat): 119035718
Entry
119035718         CDS       T07223                                 
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
  KO
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
Organism
ajm  Artibeus jamaicensis (Jamaican fruit-eating bat)
Pathway
ajm00230  Purine metabolism
ajm00670  One carbon pool by folate
ajm01100  Metabolic pathways
ajm01523  Antifolate resistance
Module
ajm_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:ajm00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    119035718 (GART)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    119035718 (GART)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    119035718 (GART)
Enzymes [BR:ajm01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.2  phosphoribosylglycinamide formyltransferase 1
     119035718 (GART)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.3  Cyclo-ligases
    6.3.3.1  phosphoribosylformylglycinamidine cyclo-ligase
     119035718 (GART)
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.13  phosphoribosylamine---glycine ligase
     119035718 (GART)
SSDB
Motif
Pfam: GARS_A Formyl_trans_N AIRS_C GARS_N GARS_C AIRS ATP-grasp CPSase_L_D2 ATP-grasp_2 ATP-grasp_3 ATP-grasp_4 Dala_Dala_lig_C Sacchrp_dh_NADP
Other DBs
NCBI-GeneID: 119035718
NCBI-ProteinID: XP_036983053
LinkDB
Position
Unknown
AA seq 1010 aa
MAARVLVIGSGGREHTLAWKLAQSNHVKQVLVAPGNAGTACSKKISNAAISISDHGALAK
FCKDEKIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGVP
TARWRAFTEPEEACSFIRSADFPALVVKASGLAAGKGVIIASSREEACGAVRQVMQDKTF
GAAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDRGPNTGGMGAYCPVP
QVSKDLLLKIKNAILQRTVDGMQQEGVPYAGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCASLPVWLENRAALTVVMASQGYPGDYAKGMEITGFAEA
QALGLEVFHAGTALKDGKVVTNGGRVLAVTAIRENLIWALEEARRGLAALKFEGAVYRKD
IGHGAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLCDLR
AAGFKDPLLACGTDGVGTKLKIAQQCNRHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLGTAEAVVAGIAKACVQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQQLP
RLERIAEGDVVVGVASSGLHSNGFSLVRKVVAKSSLRYSSRAPDGCGNQTLGDWLLTPTK
IYSQSLLPVLRSGQVKAVAHITGGGLLENIPRVLPQKLGVDLDARTWRIPAVFSWLQQQG
HLSEEEMARTFNCGVGAALVVPADLAAQVLRDIQQRQEEAWVIGRVVACPEGRPRVRVRH
LMEAVHVDRSVLKNGTANSPFPAQPKRARVAVLISGTGSNLQALIDSTQEPGSAARIVVV
ISNKAGVAGLDRAARAGIPSRVINHKLYKSRVEFDTAVDQVLEEFCADLVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFRGSNAHEQALSAGVTVTGCTVHFVAEEVDAGQIILQEA
VPVKRGDTVASLSERVKLAEHRIFPAALQLVASGTVQLGEDGKLCYVQED
NT seq 3033 nt   +upstreamnt  +downstreamnt
atggcagcgcgagtccttgtgattggcagtggagggagagagcacacgctggcctggaaa
ctggcacagtctaatcacgtcaaacaagtgttggttgcaccgggaaatgcaggaactgcc
tgctccaaaaagatttcaaatgctgccatctccatcagcgaccacggtgccctggccaag
ttctgcaaagatgagaaaattgaatttgtggttgttggaccagaagcacctctggccgcc
ggaatcgttgggaacctgacatcggcgggagtgcgctgcttcggccccacagcagaagca
gcacagttagagtccagcaaaaggtttgccaaagagtttatggaccggcacggagtcccg
actgcacggtggagggccttcaccgagcccgaagaggcctgcagcttcatccggagtgcg
gacttcccggccttggtggtgaaggccagcggcctcgcagctgggaagggggtgatcatc
gcctcgagcagggaagaggcctgcggagcagtccggcaggtcatgcaggataaaaccttt
ggagcagctggagaaaccgttgtcattgaagaacttctcgaaggagaagaggtgtcttgt
ctctgcttcactgacgggaggacggtggctcccatgccccccgcacaggaccacaagcga
ctgctggaaggggaccgaggccccaacacaggggggatgggcgcctattgtccggtgcct
caggtttctaaggatttgttgctaaaaattaaaaatgccattcttcagaggacagtggac
ggcatgcagcaggagggcgtgccgtacgcaggtgtcctctatgctggtataatgctgacc
aaggatggcccaaaggttctggagtttaattgccgtttcggtgatccagagtgccaagtg
atcctcccgcttctgaaaagcgatctttacgaagtgattcagtctaccctagacgggctg
ctctgcgcctctctgcctgtttggcttgaaaaccgtgcggctctaactgttgtcatggca
agtcagggttatccaggagactacgccaagggcatggagataacagggtttgccgaggcc
caggctttggggctggaggtgttccacgcaggcaccgccctaaaagacggcaaggtggta
actaacggagggagagtccttgcagtgactgccatccgggaaaacctcatctgggccctt
gaagaagccagaagaggactggctgctctcaagttcgagggtgctgtctacaggaaggac
ataggccacggagccatagcgttcctccagcagcccaggggcctgacttacaaggagtct
ggggtagatattgcagctggaaatatgctggtcaagaaaattaaacctctagccaaagcc
acctccagaccaggctgtgatgttgatcttggaggtttcgctggtctttgtgatttgcga
gcagccggtttcaaagatcctctgctggcctgtgggacagatggcgttggcacaaaactg
aagattgcccagcagtgcaacagacatgataccatcggccaggacttggttgctatgtgc
gtaaatgacattctggcacaaggagcagagcccctcttcttcctcgattatttttcctgc
gggaaactggacctcggcaccgcggaagctgttgtggctggaattgctaaagcgtgtgtg
caagccgggtgtgcgctcctcgggggtgagacggcagaaatgccggacatgtaccctccc
ggggaatacgacctggccggttttgccgtcggcgccatggagcgggaccagcagctcccc
cgcctggagaggatcgcagaaggggatgttgtcgttggggtggcttcatccggtcttcac
agcaacgggtttagcctcgtgaggaaagtcgtggcgaagtcttcccttcggtactcctct
cgggcgcctgacggctgtggcaaccagaccttaggggactggcttctaactccaaccaaa
atctacagccagtcactgttgcccgtgttacgctcaggacaggtcaaggccgttgcccac
attactggtgggggattgctggaaaacatcccccgagtcctcccacagaaacttggggtc
gacttagatgcccgcacctggaggatccccgcagtcttctcgtggttgcagcagcaggga
cacctctctgaggaagagatggccaggacgtttaactgcggggttggcgctgccctcgtg
gtaccagcggacctggcagcgcaggttctgagggacatccagcagcgccaggaggaagcc
tgggtgattggcagggtggtggcctgccctgaaggccgtccccgtgtgagggtcaggcac
ctgatggaagccgtgcacgtggacagatcggtgctgaagaacggtacagcgaacagtccc
ttccctgcccaaccgaaacgggccagagtggctgtcctaatttctggaacaggatcgaac
ctccaggctctcatagacagcacccaggagccaggcagcgccgcccgcatcgtggtggtc
atctccaacaaagccggcgtggccggcctggacagggcggcgagagcgggcattcccagc
agagtaatcaatcataagttgtataaaagtcgtgtagaatttgacactgcagttgaccaa
gtccttgaagagttctgtgcggacttggtctgccttgcaggattcatgaggattttatct
ggcccctttgtcagaaagtggaacgggaaaatgctcaatatccacccgtccttgctccct
tctttccggggttcaaatgcccacgagcaagccctgagcgccggtgtcacagtaacgggg
tgcaccgtgcactttgtggctgaagaagtggatgctggacagatcatcttgcaggaagct
gttccggtgaagaggggcgacactgttgccagtctgtctgaaagagtgaagctagcagaa
cacagaatctttcccgcagccctgcagctggtggccagtgggactgtccagcttggagag
gacggcaagctctgttatgtccaggaggactga

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