Artibeus jamaicensis (Jamaican fruit-eating bat): 119043705
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Entry
119043705 CDS
T07223
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
ajm
Artibeus jamaicensis (Jamaican fruit-eating bat)
Pathway
ajm00310
Lysine degradation
ajm01100
Metabolic pathways
ajm05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
ajm00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
119043705 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
119043705 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ajm03036
]
119043705 (DOT1L)
Enzymes [BR:
ajm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
119043705 (DOT1L)
Chromosome and associated proteins [BR:
ajm03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
119043705 (DOT1L)
HMT complexes
Dot1-containing complex
119043705 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
119043705
NCBI-ProteinID:
XP_036993705
LinkDB
All DBs
Position
Unknown
AA seq
1731 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKNPTALDLLHAQTVSQTAAPSPQDAYKSPQSPFYQLPPSVQRQPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDSVSLHLRGKGGLGRELEAEPGRLHLELDCSKFSLPHFNSMSPELSMNGHVAGY
ELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHTASVKASGGELHPRAEHTKENGLPYQSPGLTNGIKLSPQDPQPSSPMALQM
TGEKGSEKGLKERTYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQTRESSSTLEKQMGANGHGAGSNTAGSKGPTLAPTAGFSYTGSVAISGALAGSPA
PLASGAEPPTFDESSSSGSLFTTMSSRSSTPQHHQLLVQPRNSGPASPTHQLCVSPRLSA
AQGPLPDSSKGDLPPEAGFSDPESEAKRRIIFTISAGAGSAKQSPSNKHSPLPGGARGDS
SQSHGQDSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNIN
QPLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEQ
GSTRIERKIATISLESKSPPKTLENGGSLIGRKPMPSEPINSSKWKSTFSPIADLSLAKA
ADSPLQASSALSQNSLFAFRPTLEELGSVDAKLAAHPRKSFPGTLSGAGGLSPVSNPPNG
FAFSGGLAADLSLHSFSDGASLSHKAPEVASLGAPLSFSAPRGKEGGTEPGPFVNKRQLD
VLGGPKGEGVKGREAEVGLPMCTPSDKASSHGKVGKGRDREPDFKNGHNLFISAAAVPTG
GLLSGPGLTTAVSSAGGTAPSSQTHRPFLGTFTPGPQFALGPMSLQANLGSSVLQSLFSS
VPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGIFNHAVPSSSTHPFGASFGSGAA
CRSTTLSLTPMQAVASTPASSFQALSSVETRQPPPQPPLPMSRPPVGPPALHEPPLPNVA
LPSTPVMLPANSEPVVLQKLAPLPSNQAFLPASSAASLPPANASLSIKLASLPHKVSRPS
FMVHHQSLPGLALAQASPVIPQASSTGPSAMWVSLGMPPPYAARLAGVKPR
NT seq
5196 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagcttgagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccatgatgctgctcatgaaatcattgagacc
atccgatgggtctgtgaggaaatcccagacctcaagcttgctatggagaattatgtccta
attgactatgacaccaaaagctttgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagttgtggaagggaaccacacagcctatgaagctgaacact
cggccatccaacgggctcctgcggcacatcctgcagcaggtgtacaaccactcagtaacg
gaccctgagaagctcaacaactacgagcccttctccccagaggtgtatggggagacctcc
ttcgacctggtcgcgcagatgattgacgaaatcaagatgacagaggatgacctgtttgtg
gacctgggaagtggagtgggccaggttgtgctgcaggtcgcagcagccaccaactgcaaa
catcactacggagtcgagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggcgattttctctcggaggagtggagagagcggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaatatg
aaggaaggtggcagaattgtgtcctcgaagccctttgctcctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcacccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctgcacaccattgaccgcacc
atacttgaaaactacttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgagaaaacaagagtaatacgaccacccccacgaaggtgcct
gagagcaaggcagctgtgcctgcagacacctctgtggattctggtgctgaggaggagaaa
gcagcaacaaccgctatcaagaagccgtccccctccaaagcgcggaagaagaaactgaac
aagaagggacggaagctggccggccggaagcgtggacgtccgaagaagatgagtactgcg
aaccccgagcgtaagcccaagaagaaccctactgcactggacctgctgcacgcccagact
gtgtcccagacggccgcaccctcaccgcaggatgcgtacaagtcacctcaaagtccgttt
tatcagctacctcccagtgtgcagcggcagccccctgaccaactgctgctggcacccacc
ccacctgcactgcagaagctgctagagtccttcaagatccagtacctgcagttcctagcg
tacacgaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaatgcccggttgctgggggctgcacagcagctgtttggccactgccaggcccagaaa
gaagaaataaagagactcttccagcagaaactggatgagttgggagtgaaggctctgacc
tacagtgacctgatccaagcacagaaggagatctcagctcacaaccagcagctccgagag
cagacagagcagctggagaaggacaacagggagctaaggagccagagcctgcagctgctg
aaggctcggtgtgaggagctgaagctggactggtccacactgtcactggagaacctgctg
aaggagaagcaggccctgaagagccagatctctgagaaacagaggcattgtctggagctg
cagatcagcatcgtggagctggaaaagagccagcggcagcaggaactcctgcagctcaag
tcctgcgtgcctccggacgactctgtgtctttgcaccttcgagggaaaggcggcctgggc
cgggaactggaggcggagcctggccggctacacctggagctagactgctccaagttctca
ctgcctcacttcaatagcatgagcccagagctctccatgaatggccacgtggccggctat
gagctctgcaacacgctgagccggccctcatccaaacagaacacaccccagtacttagcc
tccccactggaccaggaggttgtgccctgtacccccagccatagcagccggccccggctt
gagaagctgtctggcttggccttgccagactacaccaggctctccccagccaagctggtg
ctgagacgccacctgagtcaggaccacacagccagtgtcaaggcatctggtggcgagcta
catccacgagctgagcacaccaaggagaatggccttccgtaccagagcccaggcctcacc
aatggcatcaagctgagccctcaggacccacagccctcatcccccatggccttacagatg
acaggagaaaagggcagtgagaagggtctgaaggagcgcacctacgccagcagcggtgag
gccatcaccagcctacctgtcagcatcccgctcagcactgtgcagcccagcaagctacct
gtcagcatccccctggccagcgtggtgttgcccagccgtgctgagaaggtgagaagcacc
cctagccctgtgcctcagacccgagagtcctcatctacacttgaaaagcagatgggtgct
aatggccatggtgctgggagcaacactgctgggagcaaaggccccaccctggcccccaca
gcaggtttctcctacactggctcagtggccatcagtggggccctggcaggcagcccagcc
ccgctcgcttctggagccgagcctcccaccttcgatgagtcctctagttcggggagcctc
tttaccaccatgagctcccgcagctccaccccacagcaccatcaactgctggtgcagccc
cggaactccggtccagcctcaccgactcaccagctctgtgttagcccccggctcagcgct
gcccagggcccactccctgattccagcaaaggagaccttccccctgaggctggcttctca
gatccagagagtgaggccaagaggaggatcatcttcaccatctcagctggtgctggcagc
gccaagcagtcgccttccaacaagcacagccctctaccggggggcgcccgcggagacagc
agccagagccatggacaggacagccgaaagcggggcaggaggaaacgggcatcagcaggg
actcccagcctgagctcgggcgtatcccccaagcgccgggccttgccatctgtcgccggt
ctcttcactcagtcttcagggtcccctctcaacctgaactccatggtcaacaacattaac
cagcctttggaaatcacagccatctcgtcccctgagagctccctgaagagctcccctgtc
ccttaccaggacaatgaccagccacccgtgctcaagaaagagaagcccctgagccaaacc
aatggggcccactactccccactgacctccgatgaggagccgggctctgaggatgagcaa
ggcagcaccagaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccg
aaaaccttagaaaatggtggcagtctgataggaaggaagccgatgcccagcgagcccatc
aacagcagcaagtggaagtctaccttctcgcccatcgccgacctcagcctggccaaggct
gccgacagcccactacaggccagctccgctctgagccagaactccctgttcgctttccgg
cccaccctagaggagcttggctcggttgatgccaagctggccgcccaccccaggaagagc
ttcccgggtacactgtcaggggctggcgggctgagtcccgtcagcaaccctcccaacggc
tttgccttcagcgggggcctggctgctgacctcagtttacacagcttcagtgatggtgct
tctctctcccacaaggcccctgaggtggccagcctgggtgcccccctgagcttttccgcc
cctaggggcaaggagggcggcacggagcccggcccctttgtgaacaagaggcagctggat
gtactgggtggcccaaaaggcgagggggtcaagggcagggaggcagaggtgggcctgccc
atgtgcacgccctcagacaaggcctcgtcgcatggcaaagtgggcaagggccgggaccgt
gagcctgacttcaagaatggccacaatctcttcatttccgccgctgctgtgcctactggg
ggcctcctcagcggtccaggcctcaccactgcagtgtcctcagcaggtggcacagccccc
tcctcccagacacaccggcccttcctgggcactttcacacctggcccgcagtttgccttg
ggccccatgtccctgcaggccaacctaggttcgtctgtgctgcagtccttgttcagctct
gtgccggctgctgctggcctagtgcacgtctcatcagctgcaacaagactgaccaactcg
catgccatgggcagcttttcctctggtgtggcaggcggtgcagttggaggtatctttaac
cacgcggtgccttcctcctccactcatccgtttggagccagtttcggcagcggggctgct
tgtcgcagcaccacgctgagcttaacccccatgcaggcggtggccagtacccccgcctct
tcctttcaggccctgtcctctgtggagacgaggcagcccccaccccagcctcctctgccc
atgagtcgtccccctgtggggccaccagcactccacgagcccccccttcctaacgtcgcc
ttgccttctactcccgtgatgctccctgctaactctgagcccgtggtcctacagaaactt
gcacccctcccatctaaccaagctttcttacctgcttcctctgctgcttctctgcctcct
gctaacgcctctctgtccatcaagctcgcctccctccctcacaaggtctcccgcccctct
ttcatggtgcaccaccagtccctgccagggctggccctggcccaggcctcgcccgtgatc
ccgcaggccagctccacggggccatccgccatgtgggtttcccttggcatgccgcctcct
tatgccgcgcgccttgcgggggttaagccgcgataa
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integrated database retrieval system
