KEGG   Artibeus jamaicensis (Jamaican fruit-eating bat): 119046845
Entry
119046845         CDS       T07223                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
ajm  Artibeus jamaicensis (Jamaican fruit-eating bat)
Pathway
ajm01522  Endocrine resistance
ajm04010  MAPK signaling pathway
ajm04012  ErbB signaling pathway
ajm04014  Ras signaling pathway
ajm04024  cAMP signaling pathway
ajm04068  FoxO signaling pathway
ajm04071  Sphingolipid signaling pathway
ajm04137  Mitophagy - animal
ajm04140  Autophagy - animal
ajm04141  Protein processing in endoplasmic reticulum
ajm04210  Apoptosis
ajm04215  Apoptosis - multiple species
ajm04217  Necroptosis
ajm04310  Wnt signaling pathway
ajm04380  Osteoclast differentiation
ajm04510  Focal adhesion
ajm04530  Tight junction
ajm04620  Toll-like receptor signaling pathway
ajm04621  NOD-like receptor signaling pathway
ajm04622  RIG-I-like receptor signaling pathway
ajm04625  C-type lectin receptor signaling pathway
ajm04657  IL-17 signaling pathway
ajm04658  Th1 and Th2 cell differentiation
ajm04659  Th17 cell differentiation
ajm04660  T cell receptor signaling pathway
ajm04664  Fc epsilon RI signaling pathway
ajm04668  TNF signaling pathway
ajm04722  Neurotrophin signaling pathway
ajm04723  Retrograde endocannabinoid signaling
ajm04728  Dopaminergic synapse
ajm04750  Inflammatory mediator regulation of TRP channels
ajm04910  Insulin signaling pathway
ajm04912  GnRH signaling pathway
ajm04914  Progesterone-mediated oocyte maturation
ajm04917  Prolactin signaling pathway
ajm04920  Adipocytokine signaling pathway
ajm04926  Relaxin signaling pathway
ajm04930  Type II diabetes mellitus
ajm04931  Insulin resistance
ajm04932  Non-alcoholic fatty liver disease
ajm04933  AGE-RAGE signaling pathway in diabetic complications
ajm04935  Growth hormone synthesis, secretion and action
ajm04936  Alcoholic liver disease
ajm05010  Alzheimer disease
ajm05012  Parkinson disease
ajm05016  Huntington disease
ajm05017  Spinocerebellar ataxia
ajm05020  Prion disease
ajm05022  Pathways of neurodegeneration - multiple diseases
ajm05132  Salmonella infection
ajm05133  Pertussis
ajm05135  Yersinia infection
ajm05142  Chagas disease
ajm05145  Toxoplasmosis
ajm05152  Tuberculosis
ajm05161  Hepatitis B
ajm05162  Measles
ajm05166  Human T-cell leukemia virus 1 infection
ajm05167  Kaposi sarcoma-associated herpesvirus infection
ajm05169  Epstein-Barr virus infection
ajm05170  Human immunodeficiency virus 1 infection
ajm05171  Coronavirus disease - COVID-19
ajm05200  Pathways in cancer
ajm05208  Chemical carcinogenesis - reactive oxygen species
ajm05210  Colorectal cancer
ajm05212  Pancreatic cancer
ajm05231  Choline metabolism in cancer
ajm05415  Diabetic cardiomyopathy
ajm05417  Lipid and atherosclerosis
ajm05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ajm00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    119046845 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119046845 (MAPK8)
   04012 ErbB signaling pathway
    119046845 (MAPK8)
   04014 Ras signaling pathway
    119046845 (MAPK8)
   04310 Wnt signaling pathway
    119046845 (MAPK8)
   04668 TNF signaling pathway
    119046845 (MAPK8)
   04068 FoxO signaling pathway
    119046845 (MAPK8)
   04071 Sphingolipid signaling pathway
    119046845 (MAPK8)
   04024 cAMP signaling pathway
    119046845 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    119046845 (MAPK8)
   04137 Mitophagy - animal
    119046845 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    119046845 (MAPK8)
   04215 Apoptosis - multiple species
    119046845 (MAPK8)
   04217 Necroptosis
    119046845 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    119046845 (MAPK8)
   04530 Tight junction
    119046845 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    119046845 (MAPK8)
   04621 NOD-like receptor signaling pathway
    119046845 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    119046845 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    119046845 (MAPK8)
   04660 T cell receptor signaling pathway
    119046845 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    119046845 (MAPK8)
   04659 Th17 cell differentiation
    119046845 (MAPK8)
   04657 IL-17 signaling pathway
    119046845 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    119046845 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    119046845 (MAPK8)
   04920 Adipocytokine signaling pathway
    119046845 (MAPK8)
   04912 GnRH signaling pathway
    119046845 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    119046845 (MAPK8)
   04917 Prolactin signaling pathway
    119046845 (MAPK8)
   04926 Relaxin signaling pathway
    119046845 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    119046845 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    119046845 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    119046845 (MAPK8)
   04722 Neurotrophin signaling pathway
    119046845 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    119046845 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    119046845 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119046845 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    119046845 (MAPK8)
   05231 Choline metabolism in cancer
    119046845 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    119046845 (MAPK8)
   05212 Pancreatic cancer
    119046845 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119046845 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    119046845 (MAPK8)
   05161 Hepatitis B
    119046845 (MAPK8)
   05171 Coronavirus disease - COVID-19
    119046845 (MAPK8)
   05162 Measles
    119046845 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119046845 (MAPK8)
   05169 Epstein-Barr virus infection
    119046845 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    119046845 (MAPK8)
   05135 Yersinia infection
    119046845 (MAPK8)
   05133 Pertussis
    119046845 (MAPK8)
   05152 Tuberculosis
    119046845 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    119046845 (MAPK8)
   05142 Chagas disease
    119046845 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    119046845 (MAPK8)
   05012 Parkinson disease
    119046845 (MAPK8)
   05016 Huntington disease
    119046845 (MAPK8)
   05017 Spinocerebellar ataxia
    119046845 (MAPK8)
   05020 Prion disease
    119046845 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    119046845 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119046845 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    119046845 (MAPK8)
   05415 Diabetic cardiomyopathy
    119046845 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    119046845 (MAPK8)
   04936 Alcoholic liver disease
    119046845 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    119046845 (MAPK8)
   04931 Insulin resistance
    119046845 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    119046845 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    119046845 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ajm01001]
    119046845 (MAPK8)
Enzymes [BR:ajm01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     119046845 (MAPK8)
Protein kinases [BR:ajm01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   119046845 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 119046845
NCBI-ProteinID: XP_036997969
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAST
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagtaagcgggacagcaatttttatagtgtagaaattggagattctacattc
acagtcctgaaacgatatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgccgcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcagaatcaaactcatgctaagcgggcttacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagcttatggatgcaaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaatcattcatcgggacttaaagccaagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggacttgccaggactgcaggaactagtttt
atgatgacaccttatgtagtgactcgctactacagagcacctgaagtcatcctagggatg
ggctacaaagagaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccgtgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaagtatgctggatatagctttgagaaactcttccccgatgtacttttc
cctgccgactcagaacacaacaaacttaaagccagtcaggcaagggatttattatccaaa
atgctggtcattgatgcatctaaaaggatctctgtagatgaagctcttcagcacccatac
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacacacgatagaagagtggaaagaattaatatacaaggaagtt
atggacttggaggagagaaccaagaatggagttatacgcggacagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcaatgtcaacagatccaactttggcctcagatacagacagcagtctagaagcctcaacg
ggaccactaggctgctgtagatga

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