Artibeus jamaicensis (Jamaican fruit-eating bat): 119050365
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Entry
119050365 CDS
T07223
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X1
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
ajm
Artibeus jamaicensis (Jamaican fruit-eating bat)
Pathway
ajm00140
Steroid hormone biosynthesis
ajm01100
Metabolic pathways
ajm05215
Prostate cancer
Module
ajm_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ajm00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
119050365 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
119050365 (SRD5A2)
Enzymes [BR:
ajm01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
119050365 (SRD5A2)
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Gene cluster
GFIT
Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
PEMT
Motif
Other DBs
NCBI-GeneID:
119050365
NCBI-ProteinID:
XP_037002524
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All DBs
Position
Unknown
AA seq
253 aa
AA seq
DB search
MPVHCQQSPVLVGSATLATLGALTLYFGEPSSYGKHTGSLATAAHLSARAAWFLQELPSF
VVPAGMLVRQPRTLLGPPETVLLGLFCVHYFHRTFVYAFLNRGRPFPIRLLFKGSVFCMG
NGLLQSYYLTYCADYPAEWYTDLRFILGVFLFILGMGINIHSDYILCQLRKPGEIIYKIP
QGGLFTYVSGANFLGEIIEWIGFALATWSLPALAFAFFSLCFLGLRAFHHHRFYHKIFKD
YPKFRKALIPFIF
NT seq
762 nt
NT seq
+upstream
nt +downstream
nt
atgcccgttcactgccagcagagcccggtgctggtgggaagcgccactttagccacgctg
ggggccctgacactgtactttggggagccctccagctacgggaagcacacggggagtctg
gccacagctgcccacctgtccgcccgcgccgcctggttcctgcaggagctgccctccttc
gtggtcccggcggggatgctcgtccgtcagccccgcactctccttggcccgcccgagact
gtgcttctgggcctcttttgcgtacattacttccacaggacatttgtttacgccttcctc
aatagagggaggccttttccaatcaggttacttttcaaaggctctgtcttctgcatggga
aacggactcctgcaaagctactacctgacttactgcgctgactatccggctgagtggtac
acagacctgcggttcatcctgggtgtcttcctgtttatcttgggaatgggaatcaacatt
catagtgactatatattgtgccagctccggaagcctggagaaatcatctataagattcca
caaggtggcctgttcacatacgtttcgggagccaatttcctcggtgagatcatcgaatgg
atcggctttgccctggccacctggtccctcccagcacttgcgtttgcatttttctcactt
tgcttccttgggctgcgagcttttcaccaccacaggttctaccacaagatctttaaggac
taccccaaatttcggaaagccctcattccatttatcttttga
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