Acinonyx jubatus (cheetah): 106966317
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Entry
106966317 CDS
T04657
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
aju
Acinonyx jubatus (cheetah)
Pathway
aju00790
Folate biosynthesis
aju01100
Metabolic pathways
aju01240
Biosynthesis of cofactors
aju01523
Antifolate resistance
aju04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
aju00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
106966317
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
106966317
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
106966317
Enzymes [BR:
aju01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
106966317
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
106966317
NCBI-ProteinID:
XP_026890993
UniProt:
A0A6J1XEU0
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Position
D4:complement(7977153..7994243)
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AA seq
580 aa
AA seq
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MSQARRHLRPALFLAAVSARVATTGVAARRGLSAWPAPQEPGMEYQDAVRALNTLQTNAG
YLEQVKRQRGDPQAQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRIDGQPISPELFTKHFWPLYRRLEETKDSSSYVSMPAYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGISSLGIDHTSILGDTVEEI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKDYRGIGELKVSRPSLLRQMPLAPVFQPTTHMRHGLRDTE
WLGRTQVLRRGPLTWYLDGAHTASSMQACVRWFRQALHRRQRPSRGSEVLVLLFNSTGDR
DPAALLKLLQPCQFDYAVFCPNLTEVSTVGNADQQNFMVTLDQVLLRCLAHQQHWSRLDE
EQAGPEPGEPTSSLLAPHPPEPRSTSSLVFSCISHALLWISQGRDPVFQPPSPPQGLFAH
PVAGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcacgccgccacctgcgacccgctcttttcctggcggcggtttctgcgcgc
gttgcaactaccggggtagcggctcggcgagggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcgcactgaacaccctgcagaccaatgctggc
tatctggagcaggtaaagcgccagcggggtgaccctcaggcacagctggaagccatgaag
ctgtacttggcacggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacttgtgcctttactgaacgtattctccgaagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcgacgggcagcccataagccctgagctcttcaccaagcacttctggcccctctac
cgccggctggaggagaccaaggacagcagcagctatgtctccatgcccgcctacttccgc
ttcctcacgctcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtg
gaggtgggcattggtggcgcttacgactgcaccaacatcatcaggaagcctgtggtgtgt
ggcatctcctctcttggcatcgaccacaccagcattctgggggacacagtggaggagatc
gcgtggcagaaagggggcatcttcaagcgtggcgtccccgccttcaccgtgctccagcct
gacggtcccctggcagtgctgagggaccgggcccagcagatctcatgtcctctctacctg
tgcccaccactggaagccctggaggaaggggggccgccgctgaccctgggcctggaggga
gagcaccagcggtccaatgccgccttggccttgcagctggctcgctgctggctacagcaa
aaggactaccggggcatcggggagctgaaggtgtccaggcccagtctcttgcggcagatg
cccctggcgcccgtgttccagcccacgacccacatgcggcatgggcttcgggacacggag
tggctgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggatggcgcg
cacaccgccagcagcatgcaggcctgcgtgcgctggttccgccaggcgctgcaccgccgc
cagaggccaagccgcggctctgaggtgcttgtcctgcttttcaactccaccggagaccgg
gatcctgcagcactgctaaagctgctgcagccctgtcagtttgactatgctgttttctgc
cctaacctgacagaggtctcaactgttggcaatgcagaccagcagaacttcatggtgacc
ctggaccaggtgttgctccgctgccttgcacaccaacagcactggagccgcctggacgag
gagcaggccggcccggagcctggtgagcccacatcctcgctgctggctccccacccgccc
gagccccgtagcaccagctccctcgtcttcagctgcatctcccacgccttgctgtggatc
agtcaaggccgggaccctgtctttcagccacccagtcccccgcagggcctcttcgcccac
cctgtggcaggcagcggggccggcgtgctccgtgaggctgccgccatccacgtgctggtc
accggcagcctgcacctggtgggcggcgtcctgaagctgctggagccggccctgtcccag
tag
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