Acinonyx jubatus (cheetah): 106970128
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Entry
106970128 CDS
T04657
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
aju
Acinonyx jubatus (cheetah)
Pathway
aju00230
Purine metabolism
aju00670
One carbon pool by folate
aju01100
Metabolic pathways
aju01523
Antifolate resistance
Module
aju_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
aju00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
106970128
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
106970128
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
106970128
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
aju04147
]
106970128
Enzymes [BR:
aju01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
106970128
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
106970128
Exosome [BR:
aju04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
106970128
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-GeneID:
106970128
NCBI-ProteinID:
XP_026907278
UniProt:
A0A6J1YRH9
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Position
C1:196597505..196625447
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AA seq
592 aa
AA seq
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MAPGQLALFSVSDKTGLVEFARNLTSVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDHADMARLDFNLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHTRVTVVCEPEDYVAICTEMQNSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELREALDLPAAASFKHVSPAGAAVGIPLSEDEARVCMVYDLYETLTPIS
TAYARARGADRMSSFGDFIALSDICDVPTAKIISREVSDGIIAPGYEDEALKILSKKKNG
SYCVLQMDPSYSPDENEVRTLFGLRLSQKRNNGVIDKSLFSNVVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLVKWKALFEEVPELLTEAEKKEWVDKLNEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADRVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccggccagctcgccttatttagtgtctctgacaaaacgggcctcgtggaattt
gccagaaacctaacttctgttggtttgaatttgatcgcttctggagggactgcaaaagct
ctcagggatgcaggtctggcagtcagagatgtctctgagctgacgggatttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccatgctggaattttggctcgtaat
atcccagaagatcatgctgacatggctagacttgatttcaatcttatcagggttgtcgtc
tgtaatctgtatccctttgtgaagacagtggcttctccagatgtaactgttgaacaggct
gttgagcagattgatattggtggagtaaccctcctgagagcagcggccaaaaaccacact
cgagtaacagtagtatgtgaacctgaggactatgtggccatttgcacagagatgcagaac
tccgacagtaaagacacctccttggagactagacgccagttagccttgaaggctttcact
catacagcacaatatgatgaagcgatttcagattacttcaggaaacagtatagtaaagga
atatctcagatgcccttgaggtatggaatgaatcctcaccaaactcctgcccagttatat
acgctgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcagagaagctttagaccttcct
gctgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactaagt
gaagatgaggccagagtctgcatggtctatgatctgtatgaaacacttacacccatatca
actgcgtatgcaagagcaagaggggctgataggatgtcttcatttggtgactttatcgca
ttatctgatatttgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
atcatcgccccaggatatgaagatgaagctttgaaaatactttctaaaaagaaaaacggg
agctactgtgttcttcagatggacccatcttacagtccagatgaaaacgaagttcgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcattgacaagtcattgttt
agcaatgttgtgaccaagaataaagatttgccagagtctgcgctcagagacctcattgta
gccaccattgctgtgaagtacacgcagtctaactccgtgtgctatgccaagaatggtcag
gttattggcattggagcaggacagcagtctcgaatacactgcacacgccttgcaggggat
aaggcgaactactggtggcttagacatcatccacaagtgctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaaccattggc
gaggatgaagatttggtaaagtggaaggcattgtttgaggaagtccctgaactgctaact
gaagcagagaagaaagaatgggttgacaaacttaatgaagtttctatcagctctgatgcc
ttctttcctttcagagataacgtagacagagctaaaaggagcggcgtggcatacattgct
gctccttctggttctgctgccgacagagttgtgatagaggcttgtgatgaactgggaata
attctcgctcatacgaatcttcggctctttcatcactga
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