Acinonyx jubatus (cheetah): 106974821
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Entry
106974821 CDS
T04657
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X7
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
aju
Acinonyx jubatus (cheetah)
Pathway
aju00230
Purine metabolism
aju01100
Metabolic pathways
aju04927
Cortisol synthesis and secretion
aju04934
Cushing syndrome
aju05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
aju00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
106974821
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
106974821
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
106974821
09167 Endocrine and metabolic disease
04934 Cushing syndrome
106974821
Enzymes [BR:
aju01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
106974821
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF3757
DUF4194
DHH
Motif
Other DBs
NCBI-GeneID:
106974821
NCBI-ProteinID:
XP_014927586
UniProt:
A0A6I9ZSC0
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Position
A1:139469871..139735522
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AA seq
775 aa
AA seq
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MEQQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALE
CFLDKHHEIIVIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASGDHEEASVLPLL
HAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHV
IQYVNPAFERMMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRK
SGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKVHRDSGDNSQTESHSFRY
KNRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVT
VAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQS
HSHLAMPITINDVPPCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFL
HCSETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALI
AATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDR
NHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAAEIEGSDCECNPTGKNFPENQI
LIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP
KSQISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2328 nt
NT seq
+upstream
nt +downstream
nt
atggaacagcaggtttcttctgcggaggtacgcattgggcccatgagactgacgcaggat
cctattcaggttttgctgatctttgcaaaggaagatagtcagagtgatggattctggtgg
gcctgtgaccgagctggttatagatgcaatattgcccggactccagagtcagccctggaa
tgctttctagataaacatcatgaaattatcgtaatagatcacagacagactcgaaacttt
gatgcagaagcagtgtgcaggtcgatccgagccacgaatccctccgagcacacggtgatc
ctggcggtggtttcccaagcatcaggcgaccatgaagaggcctcggtcctcccgctcctg
catgcaggcttcaataggagatttatggagaatagcagcataattgcttgctataatgaa
ttgattcaaatagaacacggggaagttcgctcacagttcaaactacgggcctgtaattca
gtgtttacagcattagaccactgtcatgaagccatagaaattacaagtgatgaccatgtg
attcagtacgtcaacccagcctttgaaaggatgatgggctaccacaaaggcgagctcctg
gggaaagagctcgccgagctgcccaaaagtgataagaaccgggcagaccttcttgacacc
atcaacacgtgcatcaagaagggcaaggagtggcagggggtttactatgccagacggaaa
tccggggacagcatccagcagcacgtgaagattaccccagtgattggccaaggagggaaa
attaggcattttgtctccctcaagaagctgtgttgtaccactgacaataataagcagatt
cacaaggttcatcgtgattcaggagacaattctcagacagagtctcattcatttagatac
aagaacaggaggaaagagtccattgatgtgaaatcgatatcatctcgaggcagtgatgca
ccaagcctccagaatcgtcgctatccatccatggcaaggatccattccatgaccatcgaa
gctcccatcacaaaggttataaatataatcaatgcagcccaagaaaacagccccgtgaca
gtagcagaagccttggatagagttttggaaattttacggaccacggaactgtattcccct
cagctcggaaccaaagatgaagatcctcacaccagtgatctcgttggaggcctgatgacc
gatggcttgagaaggttgtcaggaaacgagtatgtgttcactaagaatgtgcaccagagt
cacagtcaccttgcgatgccaataaccatcaacgatgtccccccttgtatcgctcaatta
cttgataatgaggaaagttgggagttcaacatctttgaattggaagctgttacacataaa
aggccattggtttacctgggcttaaaggtattttcccggtttggagtctgtgaattttta
cactgttctgaaactactcttcgggcctggctccaagtgattgaggccaactaccattct
tccaatgcttatcataactccacccatgccgccgatgtcctgcacgccactgccttcttc
ctcggaaaggaaagagtaaagggaagcctcgatcagctggatgaggtggcagcgctgatt
gccgccacagtccacgatgtggatcacccgggaaggaccaactcgttcctgtgcaacgca
ggcagtgaactcgctgtgctctataatgacaccgctgtcctggagagtcaccacaccgcc
ctggccttccagctcacggtcaaggacagcaaatgcaacattttcaagaacattgacagg
aaccattatcgaacactacgccaggctattattgacatggttttagcaacagagatgaca
aaacactttgaacatgtgaacaaatttgtgaacagcatcaataagcccctggcagctgag
attgagggcagcgactgtgaatgcaaccctactgggaagaactttcctgaaaaccaaatt
ctgatcaagcgaatgatgatcaagtgtgccgatgtcgccaacccatgccgccccctggac
ctgtgcattgaatgggctgggaggatctctgaggagtattttgcacagactgatgaagag
aagagacaggggctccctgtggtgatgccagtgtttgaccggaatacatgtagcatcccc
aaatcccaaatctctttcattgactacttcataacagacatgtttgatgcttgggatgcc
tttgcccatctgccagccctgatgcaacatttggctgataactacaaacactggaagaca
ttagatgacctaaagtgcaaaagtctgaggcttccatctgacagctaa
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