KEGG   Acinonyx jubatus (cheetah): 106980310
Entry
106980310         CDS       T04657                                 
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
  KO
K11219  non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
Organism
aju  Acinonyx jubatus (cheetah)
Pathway
aju04217  Necroptosis
aju04380  Osteoclast differentiation
aju04620  Toll-like receptor signaling pathway
aju04621  NOD-like receptor signaling pathway
aju04630  JAK-STAT signaling pathway
aju04658  Th1 and Th2 cell differentiation
aju04659  Th17 cell differentiation
aju05145  Toxoplasmosis
aju05160  Hepatitis C
aju05161  Hepatitis B
aju05162  Measles
aju05164  Influenza A
aju05165  Human papillomavirus infection
aju05167  Kaposi sarcoma-associated herpesvirus infection
aju05168  Herpes simplex virus 1 infection
aju05169  Epstein-Barr virus infection
aju05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:aju00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    106980310
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    106980310
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    106980310
   04621 NOD-like receptor signaling pathway
    106980310
   04658 Th1 and Th2 cell differentiation
    106980310
   04659 Th17 cell differentiation
    106980310
  09158 Development and regeneration
   04380 Osteoclast differentiation
    106980310
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    106980310
   05160 Hepatitis C
    106980310
   05171 Coronavirus disease - COVID-19
    106980310
   05164 Influenza A
    106980310
   05162 Measles
    106980310
   05168 Herpes simplex virus 1 infection
    106980310
   05167 Kaposi sarcoma-associated herpesvirus infection
    106980310
   05169 Epstein-Barr virus infection
    106980310
   05165 Human papillomavirus infection
    106980310
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    106980310
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aju01001]
    106980310
Enzymes [BR:aju01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     106980310
Protein kinases [BR:aju01001]
 Non-receptor tyrosine kinases
  JAK family [OT]
   106980310
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 Kinase-like Kdo FERM_C_FAK1 RIO1 ABC1 RA_2
Other DBs
NCBI-GeneID: 106980310
NCBI-ProteinID: XP_026906365
UniProt: A0A6J1YML3
LinkDB
Position
A2:157965233..157984708
AA seq 1181 aa
MPLCRWGATTRDSRPDGDEAQPMVSRGGLKVLLHWAGPDGGDPWVTFSEATLTAEEVCIH
IAHKVGITPSCLNLFALFDAQAQVWLPPNHILEVSRDMNLTLYFRMRFYFRNWHSMNPQE
PAVYRCGPTRAKSSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVAPLWELSSEEEIHHF
KNESLGMAFLHLCHLALCHGIPLEKVAKKISFKDCIPRSFRLQLQRHNALTRLRLRRLFR
RFVRAFQPGHVSQPVIMVKYLATLEQLAPRFGTERVLVCRLEEQAQAVGDPCYVQDGGQS
PPEPGPELAPRPPTHEVLVTGTGGIRWRPVQAEGPSGDGCSRNPRAGPSGKKSKAQEVGN
QPVDRPQEAPWAYFCDFQDITHVVLKECHVSIHCQDKCLELTLPSRAVALSLVSLVDGYF
RLTADSSHYLCREVAPPRLVMSIRDGIHGPLLEPFVLAKLRPEDGLYLIHWSTSHLNRLI
LTVAQRDQAPGGQQLHLRKFPIELRAGSFELEGWDRSFPSVRELRTALQGCSLRAGDDCF
SLRRCCLPRPGELSNLIIMRGSRASPGPLNLSQLSFHRVCQDDITQLSHLGQGTRTNVYE
GILRVGERGPKEGTADGGDPPTPSGDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS
HVHLAFVHGVCVHGSENIMVTEYVEHGPLDVWLRRERGHVPVAWKVAVAQQLASALSYLE
DKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWTAPECLSG
GTSTLTTAADKWGFGVTLLEICFDGEAPLQGRGPSEKECFYQKQHQLPQPSCPELATLTS
QCLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDSPASDPTVFHKRYLKKIRDLGEG
HFGKVSLYCYDPTNDGTGEMVAVKALKAGGGPQLRTGWRREIDILRTLYHKHIVKYKGCC
EDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFAQQICEGMAYLHAQHYVHRDLAA
RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWS
FGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPEKCPCEIYL
LMKNCWEAEASFRPTFQNLIPILKTVQEKYQGQAASVFNVC
NT seq 3546 nt   +upstreamnt  +downstreamnt
atgcctctgtgccgttggggtgccaccaccagggacagcaggcctgatggggatgaggct
cagcccatggtctccaggggaggcctaaaggtcctcctgcactgggctggccctgatggc
ggggacccctgggtcaccttcagcgaggccacactgaccgcagaggaggtctgcatccac
atcgcacacaaagtcggcatcactccatcctgcctcaatctcttcgccctctttgatgcc
caggcccaggtgtggctgcccccaaaccacatcttggaggtctccagagacatgaacctg
acattgtacttccgcatgaggttttatttccggaactggcacagcatgaatcctcaggag
ccggccgtgtaccgctgtgggcccaccagggccaagtcttcctcggaacaggcagagcag
ggggtgcaactcctggacccagcctcctttgagtacctctttgagcagggcaagcacgag
tttgtgaatgatgtggcaccactgtgggagctgtcgagcgaggaggagatccaccatttt
aagaacgagagcctgggcatggcctttctgcatctctgccacctcgccctttgccatggt
atccccctggagaaggtggccaagaagatcagcttcaaggactgcatcccgcgctccttc
cggctgcagctccagcggcacaacgcgttaacacggctgcgcctacggaggctcttccgc
aggtttgtgcgggccttccagccgggccacgtctcccagccggtcatcatggtcaagtac
ctggccacgctggagcagctggcaccccgcttcggcacggagcgcgtgcttgtgtgccgg
ctggaggagcaggcccaggccgtgggggacccctgctacgtccaggacgggggccagtcc
cccccggagcctgggcctgaattggcccccagaccccctactcatgaggtgctggtgaca
ggcactggtggcatccggtggcggccagtccaggcagagggtcccagtggcgatggttgc
agcaggaacccccgtgctggcccatcagggaagaaaagcaaggcccaggaggtgggcaac
cagccagtggacaggcctcaggaagcgccatgggcctacttctgtgacttccaggacatc
acccacgtggtgctaaaagagtgccacgtcagcatccactgtcaggacaagtgcctggag
ctcaccctgccttcccgggctgtggccctgtccttggtgtcgctggtggacggctatttc
cgcctgacggccgactcgagccactacctgtgccgggaggtggcccctccacggctggtg
atgagcatccgggatggcatccacgggcccttgctggagccattcgtgctggccaagctg
cggcccgaagatggcctctacctcatccactggagcaccagccacctcaaccgtctcatc
ctcacggtggcccagcgtgaccaggcacctggcgggcagcagctgcacctccgtaaattc
cccattgagctgcgggccgggagcttcgagctggagggctgggaccgctccttcccgagc
gtgcgggagctgcgcaccgccctgcagggctgctcgctgcgggccggggacgactgtttc
tccctgcgccgctgctgcctgccacggcccggagagctctccaacctcatcatcatgcgt
gggtctcgggccagccctgggccactcaacctcagccagctcagcttccaccgcgtctgc
caggatgacattacccagctgtctcacttgggccaaggcacgaggaccaatgtgtatgag
ggcatcttacgggtgggggaaagaggtcccaaggagggcacggcagatggtggggacccc
cccacgcccagtggggaccgtgggcaggagctacgagtggtactcaaggtgctggatccc
agtcaccacgacatcgccctggccttctacgagacagccagcctcatgagccaggtctcc
cacgtgcacctggcctttgtgcacggcgtctgcgtgcacggctctgagaacatcatggtg
acagagtacgtggagcacggacccctggatgtgtggctgcggcgggagaggggccacgtg
cctgtggcctggaaggtggcagtggcccagcagctggccagcgctctcagctacctggaa
gacaagagcctggttcatggtaatgtgtgtggccggaacatcctgctggcacggctggga
ctggcggagggcaccagccccttcatcaagctgagcgatcccggtgtgggcctgggcgcc
ctttccagggaggagcgggtagagaggatcccctggacagcccccgagtgcctgtcaggt
gggaccagcaccctaaccactgcagctgacaaatggggctttggtgtcaccctcctggag
atctgcttcgacggggaggcccctctgcagggccgcggcccttctgagaaagagtgcttc
taccagaagcagcaccagcttcctcagccctcatgcccggagctggccacactcaccagc
cagtgcctgacctatgaaccagctcagcggccctccttccgcaccatcctgcgtgacctc
actcagctgcagccccagaatcttgctgacgtcttggctgtgaaccccgactcgcctgca
tcagaccccaccgttttccacaagcgctatttgaaaaagatccgggatctgggcgagggt
catttcggcaaggtcagtctgtattgctacgacccgactaacgacggcaccggcgagatg
gtggctgtgaaggccctcaaggcaggcgggggcccccagctccgcactggctggcggcgg
gagatcgacatcctgcgcacgctctaccacaagcacatcgtcaaatacaagggatgctgt
gaggaccaaggagagaagtcggtgcagctcgttatggagtacgtgcctctgggcagcctc
cgggactaccttccccggcacaacgtcggactggcccaactgctactcttcgcccagcag
atctgtgagggcatggcctaccttcatgcacagcactacgtccaccgagacctggctgcc
cgcaacgtgctgctggacaacgacaggctggtcaaaatcggggactttggcctagccaag
gctgtgcctgaaggccatgagtactaccgcgtgcgcgaagatggggacagccccgtattc
tggtatgctccagagtgcctgaaggagtgtaagttctactatgcatccgacgtctggtcc
ttcggggtcaccatgtatgagctgctgacctactgtgactccagccagagccccccttcg
aaattcatcgagctcataggcctcacccaagggcagatgacggtgctgaggctcactgag
ctgctggaacgaggggagaggctgccgcggccagagaaatgcccttgcgagatctacctc
ctcatgaagaactgctgggaggcagaggcctcattccgccccactttccagaacctcatc
cccattctcaagacggtccaggagaaataccagggccaggccgcctcagtgttcaatgtg
tgctga

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