Acinonyx jubatus (cheetah): 106986899
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Entry
106986899 CDS
T04657
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
aju
Acinonyx jubatus (cheetah)
Pathway
aju05012
Parkinson disease
aju05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
aju00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
106986899
05022 Pathways of neurodegeneration - multiple diseases
106986899
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aju01001
]
106986899
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
aju04131
]
106986899
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
aju04147
]
106986899
Enzymes [BR:
aju01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
106986899
Protein kinases [BR:
aju01001
]
Serine/threonine kinases: TKL group
LRRK family
106986899
Membrane trafficking [BR:
aju04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
106986899
Exosome [BR:
aju04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
106986899
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
LRR_9
Arf
WD40_CDC20-Fz
Beta-prop_RSE1_2nd
Beta-prop_EML_2
LRR_NXF1-5
LRR_13
AAA_22
T2SSE
nSTAND3
Ank_2
ABC_tran
Kdo
PduV-EutP
MMR_HSR1
GTP_EFTU
SRPRB
G-alpha
AAA_7
Beta-prop_WDR19_1st
TsaE
AAA_16
ARM_CUL7_CUL9
TniB
cobW
MobB
WD40_Prp19
WD40_WDHD1_1st
AAA_29
Septin
NACHT
FtsK_SpoIIIE
AAA_23
SRP54
LRR_6
Beta-prop_HPS5
Motif
Other DBs
NCBI-GeneID:
106986899
NCBI-ProteinID:
XP_026891707
UniProt:
A0A6J1XGT8
LinkDB
All DBs
Position
B4:66494764..66632062
Genome browser
AA seq
2527 aa
AA seq
DB search
MASGSCQGCEEEDEETLKKLIVRLNNVQEGKQIETLVQIMEDLLVFTYADHASKLFQGKN
VHVPVLIVLDLYMRVASVQQVGWSLLCKLIEICPNTMQSLMGPQDIGRDWEVLGIHQLIL
KMLTVHNASVNLLTVGLKALDLLLTSGKITLLILDEETDIFLLIFDAMRTFSANDEVQKL
GCKALRVLFERVSEEQLTEFVENKDYMILLNALKNFKDEEEIVLHVVHCLHSLAIPCSNV
EVLMSGNVRCYNIVVEAMKAFPDNEKIQEVSCCLLHRLTLGNFFNILVLNDVHEFVVKAV
RRYSENATLQIAALSCLALLTETIFLNQDLEEKNENQENDDEEEEKLFWLEACYKALTWH
RKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASAN
ALSTLLEQNVNFRKILLSKGIYLNVLELMQKHIHSPEVAESGCKMLNHLFEGSNASMDTM
VVVAPKIITVMRYHEASLSVQLEALRAILHFIVPGMPEESKEDTEYQHKLHMVKKQCFRN
DIHKLVLAALNRFIGNPGIQKCGLKVISSIAHFPDALQVLSLEGAIESVLHTLQMYPDDQ
EIQCLGLGLIGCLITKKNLCIGTGHLLAKILVSSLQRFKDMAEVQIKGFQTILTILELSV
SFSNLLVHHSFDSVIFHQMSSSIMEQKDQQFLNLCCKCFAKLAMDDELKSVMLEKACDQN
NSIMVECLLLLGADANRTKEATSLICQVCEKASSPKLVELLLNGGSREQDVRKALTISIG
KGDSQIISLLLRRLALDLANNSICLGGFCIGKIEPSWLGPLFPDRTSNLRKETNIGSTLA
RMVLRYQMKSVVEEGAASGSGGNFPEEVLDKFDEWTFIPDSCVDSVFGQSDDLDSEGSEG
SFLVKRKSNSISVGEFYRDRALQRCSPNLQRHSNSLGPIFDHEDLLRRKRKILSSDDSLR
SSKLQSHMRHSDSISSLASEREYITSLDLSANELRDIDALSQKCCISGHLEHLEKLELHQ
NGLTNFPQQLCETLKCLTHLDLHSNKFTSFPSYLLKMNCIANLDISRNDINPSVVLDPAV
KCPTLKQFNLSYNQLSSFPENLGDVVEKLEQLILEGNKISGICSHLSLKELKILNLSKNH
ITSLSEDFLEACPKVESFSARMNYLAAVPFLPSSLTSLKLSQNRFTCVPETILNLPHLRS
LDMSSNDIQYLPSPAHWKSLNLRELLFSFNQISVLDLSEKAHVWSRVEKLHLAHNKLKEI
PPEIGCLENLTSFDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDIIR
FLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLTKSKKSDPGVQSATVGIDVKDWPIQI
RGKGKKDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKA
RASSSPVILVGTHLDVSDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAKL
RKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILLERKNVPIEFPVIDRKRLLQLVKEN
QLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKVMAQILTVKVEGYPK
HPKGIISRRDVEKFLSKKKRFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVI
ELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYL
NWSPEAYCLVGSEVLDHHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDI
CGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPEQPRLTIPISQIAPDLI
LADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQE
LVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVAD
GLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRA
PEVARGNVIYNQQADVYSFGLLLYDILTTGGRIAEGLKFPNEFDELAIQGKLPDPVKEYG
CAPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMRHISIPKNFIVECMVATNH
NSKSASIWLGCGHTDKGQLSFLDLNMEKHTSEEVTDSRILCLALVHLPAEKESWIVCGTQ
SGMLLVISTEDGKKRHTLKKMTDSVTCLYCNSVPKQSKQKNFLLVGTADGNLAIFEDKTV
KCKGAAPLKILNIGNVSTPLMCLSESMNSTEKNIMWGGCGTKLFSFSDDFTIQKLIETKT
NQLFSYAAFSDSNIIAVVVDTALYVAKKNSPFVEVWDKKTEKLCELIDCVHFLKEEMVKV
NTESKHKISYSGRVKTLCLQKNTALWIGTGGGHVLLLDLSTRRIIRIVHNFCDSVRVMMT
AQLGSLKNVMLVLGYIRKSTEGTQHQKEIQSCLSVWDINLPHEVQNLEKHIEVRNELAEK
MRRISVE
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggtagctgtcaggggtgcgaggaggaggacgaggaaactctgaagaagttg
atagtcaggctgaacaatgtccaggaaggaaaacagatagagaccctggtccaaattatg
gaggatttgctggtgttcacgtacgcggaccacgcctccaagttatttcaaggcaaaaat
gtccacgtgcctgtgttgatcgtcttggacttgtatatgagagtcgctagtgtgcagcag
gtgggttggtcacttctatgcaaattgatagaaatctgtccaaatacaatgcaaagctta
atgggaccgcaggatattggacgtgattgggaagtacttgggatccaccaactgattctt
aaaatgctaacagttcataatgccagtgtaaacctgttaacagttggactaaaggcctta
gatctcctcctaacttcaggtaaaatcactttgctgatattggatgaagagactgatatt
ttcttgttaatttttgatgccatgcgcacattttcagccaatgacgaagtccaaaaactt
ggatgcaaagctttacgtgtgctgtttgaaagagtttcagaggagcagctgactgaattt
gttgagaataaagattatatgatcttgctaaatgcattaaaaaattttaaagatgaagag
gaaattgtgcttcatgtagtgcactgtttacactccctagcaattccttgcagtaatgtt
gaagtcctcatgagtggcaacgtgaggtgttacaatattgtggtagaagccatgaaagca
ttccctgacaatgaaaaaattcaagaagtgagttgctgcttgctccataggcttacctta
ggtaatttttttaatattcttgtattaaacgatgtacatgagtttgtggtgaaagctgtg
cggcggtattcagagaacgccacgttacaaattgcagcgctcagctgtttagcactcctc
actgagaccattttcctaaatcaagatttggaggaaaagaatgaaaatcaggagaatgat
gatgaggaagaagaaaaattgttttggttggaagcctgttacaaagcgttgacgtggcat
agaaagaacaagcacgtgcaggaagctgcatgctgggccctaaacaatctcctcatgtac
caaaacagtctccatgagaagatcggagacgaagacggccagttcccagctcatagggaa
gtgatgctctccatgctgatgcattcttcatcaaaagaagtcttccaggcctctgcaaat
gcgttgtccactctgttagaacaaaatgttaatttcagaaaaatcctcttgtcaaaagga
atatacctgaatgtattggagttaatgcagaagcatatacattctcctgaggttgcagaa
agcggctgtaaaatgctaaatcatctttttgaaggaagtaatgcttccatggatacaatg
gtagtagtggcccccaaaataataacagttatgagatatcatgaggcatcattatcagtg
cagctggaggcacttcgagctattttacattttatagttccaggcatgccagaagagtcc
aaggaagatacagaatatcaacataagctacatatggttaaaaaacagtgtttcaggaat
gatattcacaaactggtcctagcagcgttgaacaggttcattggaaatcctgggattcag
aaatgtggattgaaagtaatttcttctatagcacattttcctgatgcattacaagtatta
tccctggaaggtgctattgaatcggtacttcacacacttcagatgtatccagatgaccaa
gaaattcaatgtctgggtttaggtcttataggatgcttgattacaaagaagaatttatgc
ataggaactgggcatctgctggcaaaaattctggtttccagtttacaacgatttaaggat
atggctgaagtacagattaaaggatttcagacaatcttaacaatactggaattgtcagtg
tctttttccaacctgctggtgcatcattcctttgattcggtgatattccatcagatgtct
tccagtatcatggaacaaaaggatcaacagtttctaaacctttgttgcaagtgctttgca
aaattagctatggacgatgagttaaaaagcgtgatgttagagaaagcatgtgatcagaat
aacagtatcatggttgaatgcttgcttctgttgggagcagatgccaatcgaacaaaggag
gcaacttctttaatttgtcaggtatgtgagaaagcaagcagtcccaaattagtggaactg
ttactgaatggtggttcccgtgaacaggatgtccggaaagctctgacaataagcattgga
aaaggtgacagccagatcatcagcttactcttacggagactcgccctggatctggccaat
aatagcatttgccttggaggattttgtataggaaaaatcgaaccttcatggcttggtcct
ttgtttccagataggacatctaatttaagaaaagaaacaaatataggatccaccctagca
agaatggtgctcagatatcagatgaaaagtgttgtggaagaaggagcagcctcaggcagc
ggtgggaattttcctgaagaagttcttgataaatttgatgaatggaccttcattccggac
tcttgtgtagacagtgtgtttggtcaaagtgacgacctggatagtgaaggaagtgaaggc
tcatttcttgtgaaaagaaaatccaattcaattagtgtgggagaattttaccgagatcgt
gccttacagcgttgctcaccaaatttgcagagacattccaactcattgggacccattttc
gatcatgaagatttactgaggcgaaaaagaaaaatattgtcttcagatgactcactcagg
tcatcaaaacttcaatcccatatgaggcattcagacagcatttcttccctggcttctgag
agagagtatattacatcattagacctttcagcaaatgaactaagagacattgatgcccta
agccagaaatgctgtataagtggtcatttggagcatcttgaaaagctggagcttcaccag
aatggactcacgaactttccacaacaattgtgtgaaaccctgaagtgtttgacacatttg
gacttgcacagtaataaatttacatcatttccctcttacttgttgaaaatgaattgtatt
gccaaccttgatatctctcgaaacgacatcaacccctcagtagttttggatcctgcagtg
aagtgcccaaccttgaagcagtttaacttgtcatataatcagctgtcttcttttcctgag
aaccttggtgatgtggtagagaaattggaacagctcattttagaaggaaataaaatatca
ggaatatgttcccacttaagcctgaaggaactgaaaattttaaaccttagtaaaaaccac
attacatccctatcagaagatttccttgaggcgtgtcctaaagtggagagtttcagtgcc
agaatgaattatcttgctgctgtgccttttttgccttcttctctgacaagcctaaaattg
tcccaaaacagatttacatgtgttcctgaaacaattttaaatcttccacacttacggtcc
ttagatatgagcagcaatgatattcaatatctaccgagtcctgcacactggaaatctttg
aacttaagggaactcttgttcagttttaatcagatcagcgtcttggacttgagcgaaaaa
gcacatgtgtggtcaagagtagagaaactgcatcttgctcataataaactgaaagagatt
cctcctgagattggctgtcttgaaaacctgacctcctttgatgtcagttacaatctggaa
ctgagatcctttcctaatgaaatggggaaattaagcaaaatatgggatcttcctttggat
gaactacgtcttaattttgattttaaacatataggatgtaaagccaaagacatcataagg
tttcttcagcagcggttaaaaaaggctgtgccctataaccgaatgaagcttatgattgtg
ggaaatactgggagtggtaaaaccaccttattgcagcaactaacgaaaagcaagaaatca
gatcctggggtgcaaagcgccacagttggtatagatgtgaaggactggcctatccaaata
agaggcaaagggaagaaagacctcattctaaatgtgtgggattttgcaggtcgtgaggaa
ttctacagcactcatcctcacttcatgacccagcgggccctctacctggctgtctatgac
ctcagcaaagggcaggctgaagtcgatgccatgaagccttggctcttcaatataaaggcc
cgtgcttcttcttcccctgtgattcttgttggcacacatttggatgtttccgatgaaaag
cagcgcaaagcctgcataagtaaaatcaccaaggaactgctgaacaagcgagggtttcct
gcaataagagattaccactttgtgaatgccacagaggaatccgatgctttggcaaagctt
cggaaaaccatcataaatgagagtcttaatttcaagatccgagatcagcctgtcgttggg
cagctgattccagactgctatgtagaacttgagaaaatcattttattggaacgtaaaaat
gtgccaattgaatttcctgtaatcgaccggaaacgattattacaactcgtaaaagaaaat
cagctacagttggatgaaaatgagcttcctcatgcggttcacttcctaaatgaatcaggg
gtccttcttcattttcaagacccagcgctgcagttaagtgacttatattttgtggaaccc
aagtggctttgtaaagtcatggcacagattttgacagtgaaagtggaaggctatccaaaa
catcctaagggaatcatttcacgcagagatgtggaaaaatttctttcaaagaaaaagagg
tttccaaagaactacatgtcacagtactttaaactcctagaaaaattccagattgccctg
ccaataggagaagaatatttgctggttccaagcagtttgtctgaccacaggcctgtgata
gagctccctcattgtgagaactctgaaattatcattcgactatatgaaatgccttatttt
ccaatgggattttggtcaaggttaatcaatcgattacttgaaatttcaccttacatgctt
tcaggaagagaacgagcacttcgcccaaacagaatgtattggcgacaaggcatctacttg
aattggtctcctgaagcttattgtctggtaggatctgaagttttagaccatcatccagag
agtttcttaaaaattacagttccttcgtgtagaaaaggctgtattcttttgggccaagtt
gtggaccacatcgattctcttatggaagaatggtttcctggattactggaaattgatatc
tgtggtgaaggagaaactctgttgaagaaatgggcattatatagttttaatgatggtgaa
gaacatcaaaaaatcttgcttgatgacttgatgaagaaagcagaagaaggagaccttcta
gtcaatccggagcaaccaaggctcaccattcctatatctcaaattgctcctgacttaatt
ttggctgacctgcctagaaatattatgttgaataatgatgaattggaatttgaacaagct
ccagaattcctcttaggtgatggcagttttggatctgtttatcgagcagcctatgaagga
gaagaagtggctgtgaagattttcaataaacatacatcacttagattgttaagacaagag
ctggtggtcctttgccacctccaccaccccagcttaatatctttgctggcggctgggatt
cgtcctcgcatgttggtgatggagttagcctccaagggttcactggaccgcttgcttcag
caggacaaagccagtctcaccagaaccctacagcacaggattgcactccatgtggctgat
ggcttgagatacctccactcagccatgatcatataccgtgacttgaagccccacaatgtg
ctgctcttcaccctgtaccccaatgctgccatcatcgcaaagattgctgactatgggatt
gctcagtactgctgtagaatggggataaagacatcagagggcacaccagggtttcgtgca
cctgaagttgcaagaggaaatgttatttataaccagcaggctgatgtttattcatttggt
ttactactctatgacatcttgacaactggaggtagaatagcagagggtttgaagtttcca
aatgagtttgatgaactggcaatacaagggaaattacctgatccagttaaagaatatggt
tgtgccccatggcctatggtggagaagttaattaaaaagtgtttgaaagaaaatcctcaa
gaaaggcctacttctgcccaggtctttgacattttgaattcagctgagttaatctgtctg
atgagacatatatcgatacctaaaaactttatagttgaatgcatggttgctacaaatcat
aacagcaagagtgcaagcatctggctgggctgtgggcacactgacaaaggacagctctca
tttcttgacttaaatatggaaaaacacacttctgaggaagttactgacagcagaatactg
tgcctagctttggtgcatcttcctgctgaaaaggaaagctggattgtgtgtgggacacag
tctggcatgctcctggtcatcagtaccgaagatgggaaaaagagacatacccttaaaaag
atgactgattctgtaacttgcttatattgcaattccgttcccaagcaaagcaagcaaaaa
aactttcttctggtgggaactgctgatggcaatttagcaatttttgaagataaaactgtt
aagtgtaaaggagccgctcctttgaagatactaaatataggaaatgtcagtactccactg
atgtgtttgagtgaatccatgaattcaactgaaaaaaacattatgtggggaggatgtggc
acaaaacttttctcattttctgatgatttcaccattcagaagctcattgagacaaagaca
aatcagctgttttcttatgcagctttcagtgattccaacatcatagcagtggtggtggac
acggctctctacgttgctaagaaaaatagcccatttgtggaagtatgggataagaagact
gaaaaactctgtgaacttatagactgtgtgcactttttaaaggaggaaatggtaaaagta
aacacagaatcaaaacacaaaatatcttattctgggagagtgaaaactctctgcctccag
aagaacactgccctctggataggaactggaggaggccatgttttactccttgatctttca
actcgtcgaattatacgtatagttcacaatttttgtgattctgtcagagtcatgatgaca
gcacagttaggaagccttaaaaatgtcatgctggttttggggtatatccggaaaagtact
gaaggcacacaacaccaaaaagagatacagtcttgtttgtctgtttgggatatcaacctt
ccacatgaagtgcaaaatttagaaaaacatattgaagtaagaaacgaattagctgaaaaa
atgagaagaatatctgttgaataa
DBGET
integrated database retrieval system
