KEGG   Acinonyx jubatus (cheetah): 106987636
Entry
106987636         CDS       T04657                                 
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
aju  Acinonyx jubatus (cheetah)
Pathway
aju01522  Endocrine resistance
aju04010  MAPK signaling pathway
aju04015  Rap1 signaling pathway
aju04068  FoxO signaling pathway
aju04071  Sphingolipid signaling pathway
aju04114  Oocyte meiosis
aju04148  Efferocytosis
aju04218  Cellular senescence
aju04261  Adrenergic signaling in cardiomyocytes
aju04370  VEGF signaling pathway
aju04380  Osteoclast differentiation
aju04517  IgSF CAM signaling
aju04550  Signaling pathways regulating pluripotency of stem cells
aju04611  Platelet activation
aju04613  Neutrophil extracellular trap formation
aju04620  Toll-like receptor signaling pathway
aju04621  NOD-like receptor signaling pathway
aju04622  RIG-I-like receptor signaling pathway
aju04625  C-type lectin receptor signaling pathway
aju04657  IL-17 signaling pathway
aju04658  Th1 and Th2 cell differentiation
aju04659  Th17 cell differentiation
aju04660  T cell receptor signaling pathway
aju04664  Fc epsilon RI signaling pathway
aju04668  TNF signaling pathway
aju04670  Leukocyte transendothelial migration
aju04714  Thermogenesis
aju04722  Neurotrophin signaling pathway
aju04723  Retrograde endocannabinoid signaling
aju04728  Dopaminergic synapse
aju04750  Inflammatory mediator regulation of TRP channels
aju04912  GnRH signaling pathway
aju04914  Progesterone-mediated oocyte maturation
aju04917  Prolactin signaling pathway
aju04926  Relaxin signaling pathway
aju04932  Non-alcoholic fatty liver disease
aju04933  AGE-RAGE signaling pathway in diabetic complications
aju04935  Growth hormone synthesis, secretion and action
aju04936  Alcoholic liver disease
aju05014  Amyotrophic lateral sclerosis
aju05020  Prion disease
aju05022  Pathways of neurodegeneration - multiple diseases
aju05132  Salmonella infection
aju05133  Pertussis
aju05135  Yersinia infection
aju05140  Leishmaniasis
aju05142  Chagas disease
aju05145  Toxoplasmosis
aju05152  Tuberculosis
aju05161  Hepatitis B
aju05163  Human cytomegalovirus infection
aju05167  Kaposi sarcoma-associated herpesvirus infection
aju05169  Epstein-Barr virus infection
aju05170  Human immunodeficiency virus 1 infection
aju05171  Coronavirus disease - COVID-19
aju05205  Proteoglycans in cancer
aju05208  Chemical carcinogenesis - reactive oxygen species
aju05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
aju05415  Diabetic cardiomyopathy
aju05417  Lipid and atherosclerosis
aju05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aju00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106987636
   04015 Rap1 signaling pathway
    106987636
   04370 VEGF signaling pathway
    106987636
   04668 TNF signaling pathway
    106987636
   04068 FoxO signaling pathway
    106987636
   04071 Sphingolipid signaling pathway
    106987636
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    106987636
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    106987636
  09143 Cell growth and death
   04114 Oocyte meiosis
    106987636
   04218 Cellular senescence
    106987636
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    106987636
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    106987636
   04613 Neutrophil extracellular trap formation
    106987636
   04620 Toll-like receptor signaling pathway
    106987636
   04621 NOD-like receptor signaling pathway
    106987636
   04622 RIG-I-like receptor signaling pathway
    106987636
   04625 C-type lectin receptor signaling pathway
    106987636
   04660 T cell receptor signaling pathway
    106987636
   04658 Th1 and Th2 cell differentiation
    106987636
   04659 Th17 cell differentiation
    106987636
   04657 IL-17 signaling pathway
    106987636
   04664 Fc epsilon RI signaling pathway
    106987636
   04670 Leukocyte transendothelial migration
    106987636
  09152 Endocrine system
   04912 GnRH signaling pathway
    106987636
   04914 Progesterone-mediated oocyte maturation
    106987636
   04917 Prolactin signaling pathway
    106987636
   04926 Relaxin signaling pathway
    106987636
   04935 Growth hormone synthesis, secretion and action
    106987636
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    106987636
  09156 Nervous system
   04728 Dopaminergic synapse
    106987636
   04723 Retrograde endocannabinoid signaling
    106987636
   04722 Neurotrophin signaling pathway
    106987636
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    106987636
  09158 Development and regeneration
   04380 Osteoclast differentiation
    106987636
  09159 Environmental adaptation
   04714 Thermogenesis
    106987636
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    106987636
   05208 Chemical carcinogenesis - reactive oxygen species
    106987636
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    106987636
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    106987636
   05161 Hepatitis B
    106987636
   05171 Coronavirus disease - COVID-19
    106987636
   05163 Human cytomegalovirus infection
    106987636
   05167 Kaposi sarcoma-associated herpesvirus infection
    106987636
   05169 Epstein-Barr virus infection
    106987636
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    106987636
   05135 Yersinia infection
    106987636
   05133 Pertussis
    106987636
   05152 Tuberculosis
    106987636
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    106987636
   05140 Leishmaniasis
    106987636
   05142 Chagas disease
    106987636
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    106987636
   05020 Prion disease
    106987636
   05022 Pathways of neurodegeneration - multiple diseases
    106987636
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    106987636
   05418 Fluid shear stress and atherosclerosis
    106987636
   05415 Diabetic cardiomyopathy
    106987636
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    106987636
   04932 Non-alcoholic fatty liver disease
    106987636
   04933 AGE-RAGE signaling pathway in diabetic complications
    106987636
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    106987636
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aju01001]
    106987636
Enzymes [BR:aju01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     106987636
Protein kinases [BR:aju01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   106987636
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase
Other DBs
NCBI-GeneID: 106987636
NCBI-ProteinID: XP_026926173
UniProt: A0A6J2A9I8
LinkDB
Position
B4:complement(139098356..139107126)
AA seq 367 aa
MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSAGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPDEFVQRLQSAEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAERRV
TAAEALTHPYFESLQDTEDEPKAQKYDESFDDVDRTLDEWKRVTYKEVLSFKPPRQLGTK
VSKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctccccgccgcccgcccgcaagggcttttaccgccaggaggtgaccaagacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctccggcgcgtacggcgcc
gtgtgctcggccgtggacagccgcaccggtgccaaggtggccatcaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagcttcgcctcctcaagcac
atgcgtcacgagaacgtcatcgggctgctggacgtgttcactcctgacgaaaccctggat
gatttcacagacttttacctggtgatgccgttcatgggcaccgacctgggcaaactcatg
aagcacgagaagctgagcgaggaccgaatccagttccttgtctaccagatgctgaagggg
ctaaagtacatccatgctgctggcatcatccacagggacctgaagcctggcaatctggca
gtgaatgaggactgtgagctgaagatcctggacttcggcttggccaggcaggccgacagc
gagatgactgggtacgtggtgacccggtggtaccgtgcacctgaggtcatcttgaattgg
atgcactacacccagacggtggacatctggtcagcgggctgcatcatggcagagatgatc
acagggaagacgctgttcaagggcagtgaccacctggaccagctgaaggagatcatgaag
gtgacagggactcctcccgatgaatttgtgcagaggctgcagagtgccgaggcgaagaac
tacatgaagggcctccccgagttggagaagaaggattttgcctccatcctgactaacgca
agtcctctggctgtgaacctcctggagaaaatgctggtactggatgcagaacggcgggtg
actgcggccgaggcgctcacacacccctacttcgagtcactgcaggacacggaggatgaa
cccaaggcccagaagtacgacgagtcctttgatgatgtggatcgcacgctggacgagtgg
aagcgtgtcacatataaggaagtgctcagcttcaagcctccccggcagctggggaccaag
gtgtccaaggagacagcgctgtga

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