Alteromonas sp. Mac1: AV939_15550
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Entry
AV939_15550 CDS
T05687
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ale
Alteromonas sp. Mac1
Pathway
ale00260
Glycine, serine and threonine metabolism
ale00261
Monobactam biosynthesis
ale00270
Cysteine and methionine metabolism
ale00300
Lysine biosynthesis
ale01100
Metabolic pathways
ale01110
Biosynthesis of secondary metabolites
ale01120
Microbial metabolism in diverse environments
ale01230
Biosynthesis of amino acids
Module
ale_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ale_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ale00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
AV939_15550 (thrA)
00270 Cysteine and methionine metabolism
AV939_15550 (thrA)
00300 Lysine biosynthesis
AV939_15550 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
AV939_15550 (thrA)
Enzymes [BR:
ale01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
AV939_15550 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
AV939_15550 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AMJ87867
LinkDB
All DBs
Position
complement(3633439..3635904)
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AA seq
821 aa
AA seq
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MKVLKFGGSSLADAPRYLRVNDISTATHQTDGAAVVLSAPKGVTNALSLLCEQAAAGEDF
HPLFEKLTSTVTGIADALNEELSGFAHADVTDFIQAQLRVLNQHLDGIKLLGVAPDNIAA
GILSIGEYISVTLFSGILTAKGVKNRIIDPVTYILAEGEYLDSIADVSLSKARFTDVPVD
GSELLVMPGFVAANEAGEKVTLGRNGSDYSAAILAACIDASCCEIWTDVDGVYNADPNQV
EGAVLLDKLTYQEAMELSYFGAKVLHPKTIGPIAQHHIPCLIRNTLNPAAPGTLISNEAS
EKWTSVKGISQLENVTMFNVAGPGLKGMVGMASRVFEVMSNANISISLITQSSSEYSISF
CIQSKDADRALSLLEDAFALELQNQLLDPIEVRHDLAIVTLVGDGMRHAKGLAARFFNSL
AQARVNNVAIAQGSSERSISTVIENKRAKKAVKVIHQNFFSDRHTIDVFLVGCGNVGTEL
LSQIAKQQPALLNRNIQLRVYGIANSRKLLLNSQGIDLNQDWKPALDAASEGLSVERLQQ
FVNDNSLVNPVIVDCTSHDAIAQQYVDMMENGFHVVTPNKKANTSSIDYYRKLKKTALST
NRQYLYETTVGAGLPVIDNLQKLFSAGDVLHRFEGILSGSLSYVFGKLEEGMSLSQATGS
AKDNGYTEPDPRDDLSGMDVARKLLIMAREADLDLELSDIEIESVLPAGFAEDCSIDEFM
TQLPELDAEFAKRVDAAKAEGKVLRYIGSIEGDKCKVTIEAVPASNPLSQVKDGENALAI
NSDYYQPIPYVIRGYGAGGTVTAAGVFADILRTMPWKQMAH
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtcttaaagtttgggggctcatcacttgccgacgcaccgcgctacttgcgcgtg
aacgacattagcacggccacccaccaaaccgatggcgctgcagtggtactttctgcccct
aaaggggtaacgaatgcattgtcacttttgtgtgagcaagcagccgctggcgaagatttc
caccctctatttgaaaaattgacgtctaccgtgaccggtattgctgatgcactaaacgaa
gagctcagcggcttcgctcacgctgatgttactgactttattcaggcgcaactgcgtgta
ctcaatcagcacctcgatggcattaaattgttaggtgtagcacctgacaatattgcagcc
ggtatattaagtattggtgagtacatctcggttacgttatttagcggtatcttaacggca
aaaggcgttaaaaatcgtattatcgaccctgtgacttacattcttgcagaaggtgagtac
ttagacagcattgctgatgtttcattaagtaaagctcgttttactgatgtgcctgtagat
ggcagtgaattattggtaatgcctggttttgttgctgcgaacgaggccggtgaaaaagta
acgcttggacgcaatggctctgactactctgcggctattttagcggcttgtatcgacgcg
agctgttgtgagatctggaccgatgtagacggcgtgtataatgccgatccgaatcaggtt
gaaggcgcagtacttcttgataagctaacttatcaagaagccatggagctttcttatttt
ggtgcgaaagtacttcaccctaaaaccattgggccaattgcacagcatcatattccttgc
ctaattcgtaatacgcttaaccctgcggcacctggcacgttaattagtaacgaagccagt
gaaaaatggacctcggttaaaggcatctcacaacttgaaaatgtcactatgttcaacgtg
gcaggtcctggcctaaaaggcatggttggcatggcgagccgtgtgtttgaagtaatgtcg
aatgctaatatttctataagcctaatcactcagtcatcttctgaatactcaataagcttc
tgtattcaaagcaaagatgctgatcgcgcattaagcttgttagaagatgcttttgcgtta
gagttgcaaaaccaattgttagatcctattgaagtacgccacgacttagcgattgttacc
ctagtgggtgacggtatgcgtcatgcgaagggcttagcggcgcgcttctttaactcgttg
gcgcaagctcgcgttaataacgtggcaattgcccaagggtcttcagaacgctctatttca
acggttattgaaaataaacgggcgaaaaaagccgttaaggtaatccatcagaattttttc
tcagaccgccataccattgatgtatttttagtagggtgtggcaacgtgggaaccgagctg
ttaagccaaattgcaaaacaacagccagctttacttaatcgtaatattcagttgcgggtt
tacggtattgccaatagccgtaagttgttactcaatagccaaggtattgacctaaaccaa
gactggaaacccgcattagatgcggccagcgaagggctttctgttgaacgtttgcagcag
tttgtgaacgacaatagcttagtaaacccagttattgtggattgcaccagtcatgatgct
attgctcagcaatatgtagacatgatggaaaatggttttcacgtagtgacaccaaacaag
aaagccaatactagttcaatagactactatcgtaaattgaaaaagacggcattatctacc
aaccgtcagtacttgtacgaaaccacagtaggtgccggcttgccggttatcgataacctt
caaaagctatttagtgccggtgatgtgttgcatcgtttcgaaggtatattgtcaggcagc
ttatcttacgtattcggtaaattagaagaaggcatgtcgttatcgcaagccactggttca
gctaaagacaatgggtataccgagccagatccccgtgatgacttaagtggtatggacgtt
gcgcgtaaactgcttattatggctcgtgaagcagacctagatcttgaactttctgatatt
gaaattgaatcagtgttgccagccggttttgccgaagactgctccattgatgaattcatg
acacagttacctgaacttgatgctgaattcgctaagcgtgtagatgctgcaaaagccgaa
ggaaaagtacttcgctatattggcagcattgaaggcgataagtgtaaagtaactattgag
gcggtacctgcatctaacccattatcgcaagtaaaagacggcgaaaacgcgttggccatt
aacagcgattattaccagcctattccttatgttattcgaggctatggggcaggtggtaca
gtaacggctgcgggtgtatttgcagatatactgcgtactatgccatggaagcaaatggca
cactaa
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