Alteromonas sp. RKMC-009: DS731_15915
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Entry
DS731_15915 CDS
T05653
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
alr
Alteromonas sp. RKMC-009
Pathway
alr00260
Glycine, serine and threonine metabolism
alr00261
Monobactam biosynthesis
alr00270
Cysteine and methionine metabolism
alr00300
Lysine biosynthesis
alr01100
Metabolic pathways
alr01110
Biosynthesis of secondary metabolites
alr01120
Microbial metabolism in diverse environments
alr01230
Biosynthesis of amino acids
Module
alr_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
alr_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
alr00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
DS731_15915 (thrA)
00270 Cysteine and methionine metabolism
DS731_15915 (thrA)
00300 Lysine biosynthesis
DS731_15915 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
DS731_15915 (thrA)
Enzymes [BR:
alr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
DS731_15915 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
DS731_15915 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AYA65386
UniProt:
A0A385MYE5
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All DBs
Position
complement(3556740..3559205)
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AA seq
821 aa
AA seq
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MKVLKFGGSSLADAPRYLRVTGICMTTHQTDGAAVVLSAPKGVTNALSSLCEQAAAGDDF
QPLFEKLEQTVQGIADELNTTLDNFAHDHVSSFISERLTALKQQLEGIKLLGCAPDSVAA
GILSIGEYISVTLFSAILQSKGVVNSIIDPVEYVLAHGEYLDSIADVAMSKARFSDVKND
GSVLLVMPGFVAVNEEGEKVTLGRNGSDYSAAILAACIDADCCEIWTDVDGVYNADPNQV
EGAVLLDKLTYQEAMELSYFGAKVLHPKTIGPIAQHHIPCLIKNTLNPSAPGTLISNEAS
EKWTSVKGISQLDNITMFNVAGPGLKGMVGMASRVFEVMSNANISISLITQSSSEYSISF
CIQEKDAARAQQLLEDAFALELQNQLLDQIEVRHDLAIVTLVGDGMRHTKGLAARFFAAL
AQARVNNVAIAQGSSERSISTVIEAKKAKKAVRVIHQNFFSDRHTIDVFLVGCGNVGTEL
LGQIARQQPALLKRNIQLRVYGIANSRKLLLNAQGIDVSGDWQSALSASEESLSVERLHQ
FVNSNSLVNPVIVDCTSHEAVASQYVDMMEQGFHVVTPNKKANTDTMAYYRQLRRTAQNT
NRQYLYETTVGAGLPVIDNLQKLFAAGDVLHQFEGILSGSLSYVFGKLEEGMSLSQATSA
AKENGYTEPDPRDDLSGMDVARKLLIMAREAGLVLELSDIQIESVLPEGFAEGASIDEFM
QQLPELDAAFGQRVEEAKANDSVLRYIGSIDGDKCKVTIQAVPLTHPLAAVKDGENALAI
SSDYYQPIPYVIRGYGAGGTVTAAGVFADILRTMPWKQMAL
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtcttaaagtttggtggatcttctctggccgacgcaccccgatacctgcgtgtg
accgggatttgtatgaccacccaccaaaccgatggcgcagcagtagtgctttctgcgcca
aagggcgtgaccaacgcgctttcttctctttgtgaacaggctgctgcaggggatgacttc
cagcctctgtttgaaaagttagagcaaactgttcagggtattgcagacgaattaaacacc
accttagataacttcgcccacgaccacgtttcttcattcatctcagagcgcttgactgcg
cttaagcaacaactggaaggcattaagttgcttggttgtgctccggattctgtggctgcc
ggcatcttaagtatcggcgaatacatcagtgtgacgctgttcagtgcgattttgcaaagt
aaaggtgtggttaacagtatcatcgacccggtcgaatacgtgctggcacatggcgaatat
ctcgacagcattgctgatgtggcaatgagtaaagcccgtttcagtgacgtaaagaacgac
ggttcagtattactggttatgcccggctttgttgctgttaatgaagagggtgagaaagtc
acgcttggccggaatggttctgattactctgctgccatccttgcggcctgtatcgacgca
gactgctgtgaaatctggacggatgtagacggtgtttataacgctgacccgaatcaggtt
gaaggggcagtattacttgataagctgacttatcaggaagccatggagctgtcttacttc
ggtgccaaagtactgcacccgaaaaccattggtcctatcgctcagcaccacattccctgt
ctgatcaaaaataccctgaatccttctgcgcccggcacgctaatcagtaacgaagccagc
gagaaatggacgtcagtgaaaggtatttcgcagctcgataacatcacgatgtttaatgtt
gccggacctggcctcaaaggcatggtaggcatggcaagccgtgtgtttgaggtgatgagt
aatgccaatatctccattagcctgatcacccagtccagctcggaatacagcatcagcttc
tgtatacaggaaaaagatgcggcccgtgcacagcaactgctggaagatgcctttgctctg
gaattgcaaaaccagttgcttgatcagattgaagtgcgtcacgacttagccattgttacc
ctggtcggtgatggaatgcgtcacacaaaaggcctggcagcccggttctttgctgcattg
gcgcaagcccgtgtgaacaacgtagcgattgctcagggatcttcagagcgttccatctct
acggttatcgaagcgaaaaaggcgaagaaggcggtacgggttattcaccagaatttcttc
tccgatcgccacaccattgacgtattcctggtcggctgcggcaacgtaggtacagaattg
ctgggtcagattgcccgtcagcaacctgcactgttgaagcgcaatattcagttacgtgta
tatggtattgccaacagccgcaaactgctgcttaacgcgcagggtattgatgtgtcaggt
gactggcagtctgcactgtcagcttctgaggagtcgttaagcgttgagcgtttacaccag
ttcgttaacagcaacagtctggtaaatccggtgattgttgattgtaccagtcacgaagcg
gtagcttcacagtacgtggatatgatggagcagggcttccacgtagtgacgcctaacaaa
aaggccaacaccgacaccatggcgtattaccgccagctgcgcagaaccgcacagaatacg
aatcgccagtatttatatgaaactaccgtcggtgcgggcttgccggttatcgataacctg
cagaaactgttcgctgccggcgacgtgctgcatcagttcgaaggcattttatccggtagc
ttatcctatgtatttggtaagcttgaagaaggtatgagcttgtctcaggctaccagtgca
gcaaaagaaaatggctataccgagccggatccacgtgacgacttaagcggcatggacgtg
gcccgtaaactgctgatcatggcacgtgaagccggcctggtgcttgaactgtctgatatt
cagattgaatctgtgttaccggaaggttttgcagaaggtgcatcaattgatgagttcatg
cagcagttacctgagctggatgcagcatttggtcagcgcgtggaagaagccaaagccaac
gacagtgtattacgttatatcggcagtatcgatggtgacaagtgtaaggtaaccattcag
gcggtgccgcttacgcatcctcttgcggcggtgaaagacggtgagaacgcgctggcaatc
agcagtgactattaccagccaattccttacgttatccgcggctacggagcgggtggtacg
gtaaccgctgccggtgtgtttgctgatattctgcgtaccatgccgtggaaacaaatggcg
ctgtaa
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