Alteromonas sp. Mac2: AV940_05105
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Entry
AV940_05105 CDS
T05899
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
alz
Alteromonas sp. Mac2
Pathway
alz00280
Valine, leucine and isoleucine degradation
alz00640
Propanoate metabolism
alz00785
Lipoic acid metabolism
alz01100
Metabolic pathways
alz01110
Biosynthesis of secondary metabolites
alz01210
2-Oxocarboxylic acid metabolism
Module
alz_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
alz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
AV940_05105
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
AV940_05105
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AV940_05105
Enzymes [BR:
alz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
AV940_05105
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Motif
Pfam:
E1_dh
DXP_synthase_N
AAA_7
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
AMJ92604
UniProt:
A0AAC8XX37
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Position
1256077..1257267
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AA seq
396 aa
AA seq
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MVEDRNHLGKIKTTNRVEVIGNGLIDIPMLQLLKPDGSEHETAQLPEIDQTLALKIHDTM
EYIRILDERMVAAQRQGRISFYLASTGEEAAAVASAAALSPNDMIMSQYREQGALAFRGY
TTDQFMNQMFSNKADPNKGRQMPIHYGDKALNFMTISSPLGTQIPQASGYAYGQKMAGND
AITICYFGEGAASEGDFHAGVNMAAVLNCPVIFFCRNNGYAISTPSEEQFAGDGIASRGI
GYGVKTIRVDGNDPLAVFAATQEARRIALAEMCPVLIEAMTYRLAAHSTSDDPTGYRSRD
EEDKWRAKDPIARMANWLTHKGWFDEKQNKAKVDKARQDVLAALKVSETVPICGIEEIVE
DVYDSVPWHLQDQLTSLKAHIKQYPKKYPKTSGSVR
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
attgtggaagatagaaatcatctcggaaaaattaaaacaacaaacagggttgaagttatc
ggcaatgggttaattgatattcccatgctgcaattgctcaaaccagatggaagtgagcat
gaaactgcgcaacttccagagattgaccaaacactggcgttaaaaattcacgacaccatg
gaatacatcagaattctcgatgaaagaatggtggcagcgcagcgccaaggaagaattagt
ttttatttagcaagtacgggtgaagaagccgcagccgttgctagcgcagctgctttatcg
cccaatgacatgatcatgagccaatatcgagagcagggtgcgctggctttcagaggctat
acaactgatcagtttatgaatcaaatgttcagcaacaaagccgaccctaataaagggagg
cagatgccaatccattatggtgataaagcccttaactttatgactatttcttccccacta
ggtacgcaaataccacaagcatcaggttatgcctatgggcaaaaaatggcaggcaacgat
gccattactatttgttattttggtgaaggagctgcttcagaaggcgattttcatgctgga
gtgaatatggctgctgttctcaattgcccggttatctttttctgccggaacaatggctat
gccatttcaacgccgtcggaagaacaatttgctggagatggtattgcatcacgtggaatt
ggctacggcgtgaaaacgattcgggtagacggtaacgacccgctagcggtgtttgctgca
acgcaggaagcacgccgtatagcgttagcagaaatgtgtccggtactgatagaagcgatg
acctaccgacttgcggctcattctacgtctgacgatcctacgggctatcgttctagagat
gaagaagataagtggcgcgcaaaagatccaatcgcaagaatggcgaattggcttacccat
aagggctggtttgatgaaaaacagaacaaagccaaagttgataaagcgcgtcaagatgta
ctcgcggcgttaaaagtcagtgaaacggttcctatttgcggcatagaggaaatagttgaa
gatgtgtacgacagtgtaccctggcatctacaagatcagctgacttcgttaaaagcacat
attaaacaatatcctaaaaaatatcctaaaacgtctgggagtgttcgctaa
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