Alteromonas macleodii ATCC 27126: MASE_14545
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Entry
MASE_14545 CDS
T02246
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
amac
Alteromonas macleodii ATCC 27126
Pathway
amac00260
Glycine, serine and threonine metabolism
amac00261
Monobactam biosynthesis
amac00270
Cysteine and methionine metabolism
amac00300
Lysine biosynthesis
amac01100
Metabolic pathways
amac01110
Biosynthesis of secondary metabolites
amac01120
Microbial metabolism in diverse environments
amac01230
Biosynthesis of amino acids
Module
amac_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
amac_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
amac00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MASE_14545 (thrA)
00270 Cysteine and methionine metabolism
MASE_14545 (thrA)
00300 Lysine biosynthesis
MASE_14545 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
MASE_14545 (thrA)
Enzymes [BR:
amac01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
MASE_14545 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
MASE_14545 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AFS38411
LinkDB
All DBs
Position
complement(3383258..3385723)
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AA seq
821 aa
AA seq
DB search
MKVLKFGGSSLADAPRYMRVMEISTATHQTDGAAVVLSAPKGVTNALSLLCEQAAAGEDF
QPLFNKLNDTVTGIANNLNEELDGFAHASVVEFINSHLSVLKQHLEGIKLLGVAPDNVAA
GILSIGEYISVTLFSAMLSAKGIANRVIDPVKYVLAEGDYLDSIADVSLSKARFSDVPTD
GSEFLVMPGFVAANEAGEKVTLGRNGSDYSAAILAACIDANCCEIWTDVDGVYNADPNQV
EGAVLLDKLTYQEAMELSYFGAKVLHPKTIGPIAQHHIPCLIRNTLNPAAPGTLISNEKS
EVWTSVKGISQLDNVTMFNVAGPGLKGMVGMASRVFEVMSNANISISLITQSSSEYSISF
CIQSKDASRALTLLEDAFALELQNQLLDPIEVRHDLAIVTLVGDGMRQTKGLAARFFNSL
AQARVNNVAIAQGSSERSISTVIESKRAKKAVKVIHQNFFSDRHTIDVFLVGCGNVGTEL
LGQIEKQQPALLKRNVQLRVYGIANSRKLLLNSQGIDLSGDWKAALESASEGLSVERLHQ
FANDNSLVNPVIVDCTSHEAIAQQYVDMMESGFHVVTPNKKANTSAMSYYRKLRKTAQST
NRQYLYETTVGAGLPVIDNLQKLFSAGDTLHRFEGILSGSLSYVFGKLEEGMSLSQATQT
AKDNGFTEPDPRDDLSGMDVARKLLIMAREADLALELSDIEIESVLPEGFAEDCSIDEFM
QQLPELDASFGEKVEAAKAEGKVLRYIGSIEDGKCKVSIQAVPASNPLSQVKDGENALAI
NSDYYSPIPYVIRGYGAGGTVTAAGVFADILRTMPWKQMAH
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtcttaaagtttgggggttcttctctagccgatgcaccgcgatacatgcgcgtt
atggagattagcacggcgacccaccaaaccgacggtgctgcggttgtactctctgcccca
aagggggtaacgaacgcgctttcactactatgtgaacaagcagccgcgggtgaagatttc
cagccgttattcaataagttgaacgacacggttaccggcatcgccaacaacctaaacgaa
gaactcgacgggtttgcacatgcaagcgtggtagaattcattaatagtcacctttccgta
ttaaaacagcaccttgaaggtattaagctgcttggtgttgcacctgataatgtcgctgcc
ggtattctaagtattggtgagtacatctcggtgacgctttttagcgctatgctatctgct
aaaggtattgctaatcgcgttatcgacccggttaagtatgtgctggccgaaggcgattac
ctagacagcattgccgatgtgtcgcttagtaaagcccgcttttcagatgtgcctactgac
ggcagtgaatttcttgtcatgccggggtttgttgctgctaacgaagcgggcgagaaagtc
acgcttgggcgtaacggctcagactattcagcggccattttagcggcgtgtatagacgca
aattgctgtgaaatttggacagacgtagacggtgtttataacgctgacccgaatcaagtt
gaaggggcagtgctgttagacaagcttacctatcaagaagcgatggagctatcttatttc
ggtgctaaggtgcttcatccgaaaactatcggtcctattgcccaacaccacatcccttgt
ttgatcagaaacacactaaacccagctgcgccaggtacgctaatcagcaatgaaaaaagc
gaggtgtggacgtcagttaaaggtatttcacagcttgataacgtcaccatgtttaacgtt
gcaggccctggccttaaaggcatggtaggtatggcaagtcgtgtgtttgaggtgatgtcg
aacgccaatatttcaataagccttattacccagtcttcttcagaatactcaatcagtttc
tgtatccaaagcaaagacgccagccgagcgttaacgcttcttgaagatgcgttcgcgcta
gagcttcaaaatcaattgctagatcctattgaagtgcgtcatgacctagccattgttact
ttggttggtgacggtatgcgtcaaaccaaagggttggctgcgcgtttctttaactcgctt
gcccaagcgcgcgtaaacaacgtagccattgctcaaggctcttcagagcgctctatttca
acggtaattgaaagtaagcgtgctaagaaagcagtaaaagtcattcatcagaattttttc
tctgaccgccataccatcgacgtgttcctagtagggtgtggcaatgtgggaaccgaactg
ctaggtcaaattgaaaaacaacagcctgcgttgttaaaacgcaacgtgcagctgcgagtt
tatggtattgcaaatagccgtaagctgctgttaaacagccaaggtattgatttaagcggt
gactggaaagcggcacttgaatcggcaagcgaaggattaagcgttgaacgcctgcatcag
tttgctaacgacaatagtctggtaaacccggtgattgttgactgtactagtcacgaagcg
attgcacagcaatatgtagatatgatggaaagcggttttcacgtggtaacgccaaataaa
aaggcgaacacgagcgcaatgtcttactaccgtaagcttcgcaagaccgcgcaatcgaca
aatcgtcagtacctttacgaaaccactgtcggcgcagggctaccggttattgataacttg
caaaagctattcagcgccggcgacaccttacaccgctttgaaggaattctatcgggcagt
ttgtcttatgtatttggcaaacttgaagagggcatgagcctgtcgcaagcgacacaaaca
gccaaagacaacggtttcacagagcctgatccgcgcgatgacttaagcggcatggacgta
gcgcgcaagctgcttatcatggctcgtgaagctgatttagcgttagaactatctgacatt
gaaattgagtctgtactgccagaaggctttgctgaagactgttcaattgacgagtttatg
cagcagctgccagagttagatgcgtcgtttggtgaaaaggttgaagcggctaaagcagaa
ggtaaagtacttcgttatatcggcagcattgaagacggaaaatgcaaagtaagcattcag
gctgtaccggcaagtaaccctctttcgcaggtaaaagacggtgaaaacgcgctggcgatt
aacagtgactactatagcccaatcccttatgtaattagaggatatggagcaggtggtacg
gtaacagcagcaggggtgtttgctgacattctgcgtactatgccgtggaagcaaatggcg
cactaa
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