Alteromonas mediterranea UM4b: I636_14820
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Entry
I636_14820 CDS
T02723
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
amad
Alteromonas mediterranea UM4b
Pathway
amad00260
Glycine, serine and threonine metabolism
amad00261
Monobactam biosynthesis
amad00270
Cysteine and methionine metabolism
amad00300
Lysine biosynthesis
amad01100
Metabolic pathways
amad01110
Biosynthesis of secondary metabolites
amad01120
Microbial metabolism in diverse environments
amad01230
Biosynthesis of amino acids
Module
amad_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
amad_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
amad00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
I636_14820 (thrA)
00270 Cysteine and methionine metabolism
I636_14820 (thrA)
00300 Lysine biosynthesis
I636_14820 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
I636_14820 (thrA)
Enzymes [BR:
amad01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
I636_14820 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
I636_14820 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AGQ02804
LinkDB
All DBs
Position
complement(3334352..3336817)
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AA seq
821 aa
AA seq
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MKVLKFGGSSLADAPRYMRVMEISTATHQTDGAAVVLSAPKGVTNALSLLCEQAAAGEDF
QPLFTKLNDTVTGIANNLNEELDGFAHASVVDFINSHLSVLKQHLEGIKLLGVAPDNVAA
GILSIGEYISVTLFSAMLSAKGIANRVIDPVKYVLADGEYLDSIADVSLSKARFSDVPND
GSEFLIMPGFVAANEAGEKVTLGRNGSDYSAAILAACIDASCCEIWTDVDGVYNADPNQV
EGAVLLDKLTYQEAMELSYFGAKVLHPKTIGPIAQHHIPCLIRNTLNPAAPGTLISNEKS
EVWTSVKGISQLDNVTMFNVAGPGLKGMVGMASRVFEVMSNANISISLITQSSSEYSISF
CIQSKDAQRALTLLEDAFALELQNQLLDPIEVRHDLAIVTLVGDGMRQTKGLAARFFNSL
AQARVNNVAIAQGSSERSISTVIESKRAKKAVKVIHQNFFSDRHTIDVFLVGCGNVGTEL
LGQIEKQQPALLKRNIQLRVYGIANSRKLLLNSQGIDLSGDWSAALDSASEGLSVERLHQ
FANDNSLVNPVIVDCTSHEAIANQYVDMMESGFHVVTPNKKANTSAMAYYRKLRKTALST
NRQYLYETTVGAGLPVIDNLQKLFSAGDVLHRFEGILSGSLSYVFGKLDEGMSLSQATQT
AKDNGFTEPDPRDDLSGMDVARKLLIMAREADLELELSDIEIESVLPAGFAEDCSIDEFM
QQLPELDAAINEKVEAAKAEGKVLRYIGSIEDGKCKVSIQAVPASNPLSQVKDGENALAI
NSDYYSPIPYVIRGYGAGGTVTAAGVFADILRTMPWKQMAH
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtcttaaagtttgggggttcttctctagccgatgcaccgcgatacatgcgcgtt
atggaaattagcacggccacccaccaaaccgacggtgctgcggttgtactctctgcccct
aagggggtaacgaacgcgctttcactattgtgtgaacaagcagccgcgggtgaagatttc
caaccgttattcactaaactgaacgacacggttaccggcattgccaacaaccttaacgaa
gaactcgacggctttgcccacgcaagcgtggtagatttcatcaacagtcacctcagtgta
ttaaagcagcaccttgaaggcataaagttgcttggcgtagcgccagataatgttgcagcg
ggtatcctaagcattggtgaatatatttcggttacgcttttcagcgccatgctttcagcg
aagggcatcgctaaccgcgttatcgacccggtaaaatatgtgcttgccgatggcgaatac
ctagacagcattgccgacgtgtcgctaagtaaggcgcgtttttcagacgtaccaaacgat
ggcagtgagttcttaataatgccgggtttcgtcgccgctaatgaagcgggcgaaaaagtg
acgttaggccgcaacggttcagattattccgcagcaattttagcggcgtgtatcgatgca
agctgttgcgagatttggacagacgtagatggtgtttacaatgctgacccgaaccaagta
gaaggtgcggtactgcttgataaattgacttatcaagaagccatggaactgtcttatttt
ggcgctaaagtacttcaccctaaaaccattggccctatcgctcaacatcacatcccgtgt
ttaattcgcaatacgcttaatccagcggcgccgggtacgcttatcagcaacgaaaaaagt
gaagtatggacgtcggttaaaggtatttcacagcttgataacgttactatgtttaacgtt
gcaggccctggtcttaaaggcatggtaggcatggcaagtcgcgtgtttgaagtcatgtcg
aatgcgaatatctctatcagtttaattactcagtcttcctctgagtactcaatcagtttt
tgtattcaaagcaaggacgcccagcgtgcgttaaccttacttgaagatgcgtttgcacta
gagttacaaaatcagctgcttgatccaatcgaagtgcgtcatgatcttgccattgttacc
ttagtgggtgacggtatgcgtcaaaccaaaggcttggcggcccgtttctttaactcgctt
gcgcaagcgagagttaacaacgtagccatcgcgcagggctcttctgagcgctcaatctct
acagttattgaaagcaagcgtgcgaaaaaagcggtaaaagtcattcatcagaattttttc
tctgaccgtcataccatagacgtattcctagtagggtgtggcaacgtggggactgaactg
ctagggcagattgaaaagcagcagccggcactgttaaagcgcaatattcagctgcgtgtc
tacggtattgccaatagccgtaagctactgttaaacagccaaggtatagatttaagcggt
gactggagcgcagcacttgattcagcgagcgaagggttgagcgttgagcgcttacaccag
tttgctaatgacaacagcttagtgaacccagttattgttgactgcaccagccatgaagct
attgccaatcagtacgttgatatgatggaaagtggtttccacgtagtgacgccgaacaaa
aaggcgaataccagcgccatggcttattaccgtaagctgcgcaaaacggcactttctact
aaccgtcaatacctttatgagacgacagtgggcgcaggccttccggttattgataacctg
caaaagctgtttagcgccggtgacgttctgcaccgctttgaaggtattttatcaggcagc
ttgtcttacgtgttcggcaagcttgacgagggcatgagcctgtcgcaagcgacgcaaaca
gcaaaagacaatggctttaccgagccagatcctcgcgatgatttaagcggtatggacgta
gcgcgtaagctgcttattatggcccgcgaagccgacctagaacttgagctttccgatatt
gagattgagtcagtattgccagcaggctttgctgaagattgttccatcgacgaatttatg
cagcagctacctgaattagatgctgcgataaatgaaaaagtggaagcagccaaagcagaa
ggcaaagtacttcgctatatcggcagcattgaagacggtaagtgcaaagtaagcattcag
gctgtgccggcaagcaacccgctttcacaagtaaaagacggtgaaaacgcgctggctatt
aacagtgactactatagcccaattccttatgtgataagaggctacggcgctggtggtacg
gtgaccgcagcgggtgtgtttgcagatattttgcgtaccatgccgtggaagcaaatggcg
cactaa
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