Actinomyces marmotae: HPC72_04070
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Entry
HPC72_04070 CDS
T07249
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
amam
Actinomyces marmotae
Pathway
amam00300
Lysine biosynthesis
amam00550
Peptidoglycan biosynthesis
amam01100
Metabolic pathways
amam01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
amam00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HPC72_04070
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HPC72_04070
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HPC72_04070
Enzymes [BR:
amam01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HPC72_04070
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QKD79533
UniProt:
A0A6M8B8J2
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All DBs
Position
946646..948160
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AA seq
504 aa
AA seq
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MGCRVIARAIDELSSWAQGRLIPPAPPAAPVTRVVTDSRRAGPGSLFVAIKGERADGHDY
LAAVARAGAAAALVSDETAARAALAEAGRADGPGAAMALIVVEDTVAALGRIARGHLADL
RQRAGDRGLAVVAMTGSVGKTTTKDLTRQLLAAQGPTIAPVASFNNEIGLPLTVLEADES
TRYLVLEMGASGPDDIADLVGIAPLDAAAVLMIGHAHMGGFGSIEGVATAKSHIVRGLLP
HGTAILNLDDERAAAMGALAPAGVLTFSASGDERADLRATAVELDEAAHAVAEIHLPGAA
PRRVRLGLPGAHNVANALAALGLALAAGAGADDLLDAIACAGLESPHRMAVSDLPGGGRL
IDDSYNANIDSMTASLASLPALAGDRRRVVVISEMLELGESSAADHATVGALAADAGASL
LVAIGAGAAPAAEAARQRGVEVVETPDADGAIARIPSLLAPGDAVLVKGSHGSGAWRVAD
HLAAGGPTAVGHEATDGRDGKDAR
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atggggtgccgcgtgatcgcccgcgcgatagacgagctctcctcctgggcccagggccgc
ctcatcccccccgccccgccagcggctccggtgacccgagtcgtcaccgactcccgccgg
gccgggccgggctcgctcttcgtggccatcaagggcgagcgcgcggacggccatgactac
ctcgccgccgtcgcccgcgccggcgccgcggccgccctggtcagcgatgagaccgcggct
cgcgccgccctcgccgaggccggccgggccgatgggcccggcgccgcgatggcgctcatc
gtcgtggaggacaccgtagctgccctcgggcgcatcgctcgagggcacctcgcggacctg
cgccagcgcgcgggggatcggggtctggccgtcgtcgcgatgaccggctcggtgggtaag
accaccaccaaggacctcacccgccagctcctggccgcccaggggcccacgatcgcgccg
gtcgcctcgttcaacaacgagatcggtctgcccctgaccgttctcgaggcggacgagtcc
acccgctacctcgtccttgagatgggcgcctccggacctgatgacatcgcggacctggtg
gggatcgccccactggacgccgccgccgtcctcatgatcggccacgcccacatgggcggc
ttcggctccatcgagggcgtcgccactgctaagagccatatcgtgcgcggcctgcttccc
cacggcaccgccatcctcaacctcgacgacgagcgggccgccgccatgggcgccctcgcg
ccggccggtgtcctcacgttctccgccagcggtgacgagcgcgcggacctgcgcgccacc
gccgtggagctcgacgaggccgcccacgccgtcgccgagatccacctgcccggcgccgcc
ccccgccgcgtgcgcctgggactgcccggcgcccacaacgtcgccaatgccctggcggcc
ctcgggctggccctcgccgcgggcgcgggcgcggatgacctcctggatgccatcgcctgc
gcggggctggagagcccccaccgcatggcggtcagcgatctgcccggaggcggccggctc
attgacgattcctacaacgccaacattgactcgatgaccgcctcgctcgcctccctgccc
gcgctggccggggaccgccgccgtgtcgtcgtcatctcggagatgctcgagctcggagag
agttccgccgccgatcacgccaccgtaggggcgctcgccgctgacgccggcgcctccctc
ctggtggccatcggcgcgggcgcggcgcccgcggccgaggccgcccgccagcgcggcgtg
gaggtcgttgagacccccgacgccgacggcgccatcgcccgcatcccctcgctcctcgcc
cccggggacgcggtcctggtcaagggctcgcacggatcgggcgcctggcgcgtggccgac
cacctggccgccggtggcccgacggccgtcggccacgaagcgactgatggacgtgatgga
aaggacgcccgatga
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