Actinomadura madurae: LUW76_01635
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Entry
LUW76_01635 CDS
T08933
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
amaz
Actinomadura madurae
Pathway
amaz00280
Valine, leucine and isoleucine degradation
amaz00640
Propanoate metabolism
amaz00785
Lipoic acid metabolism
amaz01100
Metabolic pathways
amaz01110
Biosynthesis of secondary metabolites
amaz01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
amaz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LUW76_01635
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LUW76_01635
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LUW76_01635
Enzymes [BR:
amaz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LUW76_01635
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GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
PBP_like
PFOR_II
LPD26
Motif
Other DBs
NCBI-ProteinID:
URM93149
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All DBs
Position
364254..366380
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AA seq
708 aa
AA seq
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MPEPADAHFLETAATLEAPASPAPDGPLTGERCLELFDAQLGSRHLDLAARHLRAEGHGY
YTIGSSGHEGNAAVAAVLRPDDPALLHYRSGAFFLERARQVPGRNPLRDVLLGLVAAAEE
PIAGGRHKVFGSRPLHIIPQTSTIASHLPRALGVAFAIERAARLGLDSPWPRDAVAVCSF
GDASANHSTAAGAVNAAINCGFQGLPLPLLLVCEDNGIGISVRTPPGWIHAAYGSRPGLP
YFHADGCDLADAYAVAAQAAGWVREHRRPAFLHLRTVRLMGHAGSDVESSYRTPAEMAAD
LDRDPLLRTARLLVERGAATAEDVVGLYEAKRAEVMALAGKVAGAPRLGSAAEVMAPLRP
AAAGRGEARAEGERVTLAQAINRTLGELLDEHPGMVVFGEDVARKGGVYGVTRGLMRRAG
PARVFDTILDEQSILGLALGFGTAGMLPVPEIQYLAYLHNAADQIRGEAATLPFFSSGQY
ANPMVVRIAGYAYQKGFGGHFHNDNAVAALRDIPGLVVASPSRPDDAAGMLRACADAAER
EGRVCAVLEPIALYHARDLHEDGDGGWLAPAGGTVPIGRARSYGDGRDLTIVTFANGLRM
SLRAARRLEARGVGCRVLDLRWLAPLPVEDLLREARATGTVLVADETRRTGGVSEGVLAA
LADAGFQGKAARVAGEDSFIPLGDAAYHVLLSEDAIEDAAGKLLTSSR
NT seq
2127 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagcccgccgacgcccacttcctggagacggccgcgacccttgaggcgcccgcc
tcgccggccccggacgggccgctcaccggcgagcgctgcctggagctgttcgacgcccag
ctcggcagccggcacctggacctcgcggcccggcacctgcgggcagagggccacggctac
tacacgatcgggtcgtccggccatgaagggaacgcggccgtcgcggccgtcctgcgcccg
gacgacccggccctcctgcactacaggtcgggggcgttcttcctggagcgcgcccgccag
gtccccggccggaacccgctgcgggacgtgctcctcggcctggtcgccgccgcggaggag
cccatcgcgggcgggcgccacaaggtgttcgggagccgcccgctgcacatcatcccgcag
acctccaccatcgcctcgcacctcccgcgcgcgctcggcgtggccttcgccatcgaacgg
gccgcccgcctcggcctggactcgccgtggccgcgcgacgccgtcgcggtgtgctccttc
ggggacgcctccgccaaccactcgacggccgcgggcgccgtcaacgcggcgatcaactgc
gggttccagggcctgcccctgccgctcctcctcgtctgcgaggacaacgggatcggcatc
agcgtccgcaccccgcccggctggatccacgccgcgtacgggtcccggcccggcctcccc
tacttccacgccgacggctgcgacctcgccgacgcctacgccgtggccgcgcaggcggcc
ggctgggtacgcgagcaccgccgtcccgcgttcctgcacctgcgcaccgtccggctgatg
ggccacgccggctccgacgtcgagtcgtcctaccggacgcccgccgagatggccgccgac
ctcgaccgcgaccccctcctgcggaccgcgcgcctcctggtcgagcgcggcgcggcgacc
gccgaggacgtcgtcggcctctacgaggccaagcgcgccgaggtcatggccctcgccggg
aaggtcgccggtgctcctcgcctcggctccgccgccgaggtcatggcgccgctccggccc
gccgcggccggccggggcgaggcgcgggcggagggggagcgggtcacgctggcgcaggcg
atcaaccggacgctcggcgagctgctggacgagcacccggggatggtcgtcttcggcgag
gacgtggcgcgcaagggcggcgtctacggcgtcacgcgcgggctgatgaggcgcgccggg
cccgcgcgggtgttcgacacgatcctggacgagcagtcgatcctcggcctcgcgctcggc
ttcgggacggccgggatgctgcccgtgcccgagatccagtacctcgcctacctgcacaac
gccgccgaccagatccggggcgaggcggcgacgctgccgttcttctcgtccgggcagtac
gccaacccgatggtcgtgcggatcgccggctacgcctaccagaagggcttcgggggccac
ttccacaacgacaacgccgtggccgcgcttcgcgacatcccgggcctggtcgtcgcgtca
ccgtcccgccccgacgacgccgcggggatgctgcgcgcgtgcgcggacgccgccgagcgc
gagggcagggtgtgcgcggtgctggagccgatcgcgctctaccacgcgcgcgacctgcac
gaggacggcgacgggggctggctcgccccggcgggcgggacggtcccgatcgggcgcgcc
cgctcctacggcgacgggcgggacctcacgatcgtcacgttcgccaacggcctgcgcatg
agcctgcgcgccgcccgccgcctggaggcccgcggcgtcggctgccgggtgctcgacctg
cgctggctggccccgctgcccgtcgaggacctgctgcgcgaggcccgcgccacgggcacc
gtcctggtagcggacgagacccgccgcaccggaggcgtctccgagggcgtcctggcggcc
ctcgccgacgcgggcttccaggggaaggcggccagggtcgccggcgaggacagcttcatc
cccctcggcgacgccgcctaccacgtcctgctgtccgaggacgccatcgaggacgccgcc
gggaagctgctcacgtcgtctcgatga
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