Actinomadura madurae: LUW76_02025
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Entry
LUW76_02025 CDS
T08933
Symbol
menD
Name
(GenBank) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
amaz
Actinomadura madurae
Pathway
amaz00130
Ubiquinone and other terpenoid-quinone biosynthesis
amaz01100
Metabolic pathways
amaz01110
Biosynthesis of secondary metabolites
amaz01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
amaz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
LUW76_02025 (menD)
Enzymes [BR:
amaz01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
LUW76_02025 (menD)
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Motif
Pfam:
TPP_enzyme_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
URM93212
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Position
441520..443187
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AA seq
555 aa
AA seq
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MNPATALATVVVDELLRCGMTDVVLAPGSRSAPLALALHAAEEAGRVRMHVRIDERSGSF
LGLGLAKRSGRPVALVCTSGTAAANFHPAVVEAHESGVPLLVVTADRPPELRDTGANQTI
DQVKLYGTAVRWSTEIGVPENRPGMVAYWRSLMSRAWGLAQAPVPGPVHVNASFREPLIP
DGDETWCEPLDGDATGAWTKVRPATPGSVLHVPPTRRGVLVVGDGAMNVKRYVAAASMAG
WPVLAEPNGNARYGDHALSSHHFLLGVPEFVERHRPEVVVTLGKPGLSRPLLSLLRRAEE
HIVLAPDLAHWPDPVRSATQVAPEVEIPVVSGDDAWLKSWRTADLAAAAAVDAVLDAVPE
VSEPRLARDLVAGLPGGSLLFTAASMPIRDLDQVMRPRRGIRIMANRGASGIDGLVSTAM
GAALAHSGRSYALLGDLAFLHDQNGLIVGPRDRRPDLAIIVVNNRGGGIFSLLPQAALHG
PFERVFGTPHQVDLEAVAAAHGVPYRRLDAAADLPKAMAGEGLRIVEARTDREANAALHA
DLRQAAQAAVRAVLA
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
gtgaacccggcgaccgcgctggcgaccgtcgtggtcgacgagctgctgcggtgcgggatg
accgacgtggtgctggcgccggggtcgcggtcggcgccgctggcgctggcgctgcacgcc
gccgaggaggcgggccgggtccgcatgcatgtgcggatcgacgagcggtcggggtcgttc
ctcgggctcggcctggccaagcggtcgggccgtccggtggcgctggtgtgcacgtcgggg
acggcggcggcgaacttccacccggcggtggtggaggcgcacgagtcgggcgtcccgctg
ctggtggtgacggcggaccgtccgccggagctgcgcgacaccggcgcgaaccagacgatc
gaccaggtgaagctgtacgggacggcggtgcggtggagcaccgagatcggcgtgccggag
aaccgaccgggcatggtggcgtactggcggtcgctgatgagccgcgcgtgggggctggcg
caggcgccggtcccggggccggtgcatgtgaacgcgtcgttccgggagccgctgatcccg
gacggcgacgagacgtggtgcgagccgctcgacggtgacgcgacgggcgcgtggacgaag
gtgcggccggcgacgccggggtcggtgctgcacgtcccgccgacgcggcgcggcgtcctg
gtggtcggggacggcgcgatgaacgtcaagcggtacgtggcggccgcgtcgatggccggc
tggcccgtgctggccgagccgaacggcaacgcccgctacggcgaccacgcgctgtcgtcg
caccacttcctgctgggcgtcccggagttcgtggagcggcaccgtcccgaggtggtggtg
acgctgggcaagccggggctgtcgcgcccgctgctgtcgctgctgcgccgggccgaggag
cacatcgtgctggcgccggacctggcgcactggcccgacccggtccggtcggcgacgcag
gtcgctccggaggtggagatcccggtggtgtcgggcgacgacgcgtggctgaagtcgtgg
cggacggcggacctggccgccgcggcggcggtggacgcggtgctggacgcggtgccggag
gtcagcgagccgcggctggcacgggacctggtcgcggggctgccgggcgggtcgctgctg
ttcacggccgcgagcatgccgatccgcgacctggaccaggtgatgcggccgcggcgcggc
atccggatcatggcgaaccggggcgcgagcggcatcgacgggctggtgtcgacggcgatg
ggggcggcgctggcgcacagcggccgctcctacgcgctgctgggcgacctcgcgttcctg
cacgaccagaacgggctgatcgtggggccgcgggaccgccggcccgacctggcgatcatc
gtggtgaacaaccggggcggcgggatcttctcgctgctgccgcaggcggcgctgcacggc
ccgttcgagcgggtcttcgggaccccgcaccaggtggacctggaggcggtcgccgcggcg
cacggcgtcccgtaccgccgcctggacgcggcggcggacctgcccaaggcgatggcgggg
gaggggctgcggatcgtcgaggcccgcaccgaccgggaggcgaacgcggcgctgcacgcc
gacctccgccaggccgcccaggccgccgtccgcgccgtcctcgcctga
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