Actinomadura madurae: LUW76_30465
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Entry
LUW76_30465 CDS
T08933
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
amaz
Actinomadura madurae
Pathway
amaz00860
Porphyrin metabolism
amaz01100
Metabolic pathways
amaz01110
Biosynthesis of secondary metabolites
amaz01120
Microbial metabolism in diverse environments
amaz01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
amaz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
LUW76_30465
Enzymes [BR:
amaz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
LUW76_30465
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
LUW76_30465
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
URN01716
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Position
6488337..6489857
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AA seq
506 aa
AA seq
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MGPGDPGLLTLRAAAELERADTVIVSRAHCPAEILTHCRADTEIIDTAEGDPVKLAARAA
KAGRRVVRLFRGDPGVACSFAAEGGALAKAGVPFEVVPGVSSVTGVPGYAGIPLTDARNR
EIRIVDASEGGVDWERYAAPDTTLVILGAEGAVAEVAKGLVAAGRPDSTPAAMTSLGTTT
EQETVVSTLQKLASDTKGMEAPALIIVGNVVSWRDKLSWFETKPLFGWRVLVPRTKEQAA
SLSDQLRGYGAVPDEVPTISVEPPRTPQQMDRAVKGLVTGRYEWVVFTSTNAVKAIREKF
TDYGLDARAFAGLKVAAVGEQTAAALVEFGVQPDLTPSGEQSGEGLAREWPPYDEDLDPI
NRVLLPRADIATDVLIARLTELGWECEDVTAYRTVRAAPPPAPIREAIKGGGFDAVLFTS
SSTVKNLIGIAGKPHNVTVIAVIGPQTAKTAREYGLRVDVEADKPSVSALAEALAEYGAK
RRAAQIEAGDPLRKPSQMRRGARRRR
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
atgggcccgggtgaccccgggctgctgaccctgcgcgccgccgccgagctggagcgcgcc
gacacggtcatcgtgagccgggcgcactgcccggccgagatcctcacgcactgccgcgcc
gacaccgagatcatcgacacggcggagggcgacccggtgaagctcgccgcccgcgccgcg
aaggcgggccgccgggtggtccggctgttccgcggtgacccgggcgtggcgtgcagcttc
gccgccgagggcggtgcgctggccaaggccggcgtcccgttcgaggtggtgcccggcgtg
tcgtcggtgacgggcgtgcccggctacgcgggcatcccgctgacggacgccaggaaccgc
gagatccggatcgtggacgcctccgagggcggcgtcgactgggagcgctacgcggccccg
gacacgaccctcgtcatcctcggcgccgagggcgcggtggcggaggtcgcgaagggcctc
gtcgccgccgggcgccccgactccaccccggccgcgatgacgagcctcggcacgacgacc
gagcaggagaccgtggtctccacgctgcagaagctcgcgtccgacaccaagggcatggag
gcgcccgccctgatcatcgtcgggaacgtggtgagctggcgcgacaagctgtcctggttc
gagaccaagccgctgttcggctggcgggtgctggtgccgcggacgaaggagcaggccgcg
tcgctgtcggaccagctgcgcgggtacggggccgtcccggacgaggtcccgacgatctcc
gtcgagccgccgcgcaccccgcagcagatggaccgggccgtgaagggcctcgtcaccggc
cgctacgagtgggtcgtgttcacctccacgaacgcggtgaaggcgatccgggagaagttc
accgactacggcctggacgcccgcgcgttcgccggcctcaaggtcgccgccgtcggcgag
cagaccgccgccgcgctggtcgagttcggcgtccagcccgacctgaccccgtcgggcgag
cagtccggcgagggcctggcgcgggagtggccgccctacgacgaggacctcgacccgatc
aaccgggtgctgctgccgcgcgccgacatcgccaccgacgtgctcatcgcccggctgacc
gagctcggctgggagtgcgaggacgtgaccgcctaccggacggtccgggccgcgccgccg
cccgcgccgatccgcgaggcgatcaagggcggcgggttcgacgcggtgctgttcacctcg
tcctccacggtgaagaacctcatcgggatcgccggcaagccgcacaacgtgacggtcatc
gccgtgatcggcccgcagacggccaagacggcgcgcgagtacgggctgcgggtggacgtc
gaggcggacaagccgtcggtatccgccctcgcggaggcgctcgcggagtacggtgccaag
cggcgggcggcccagatcgaggcgggggatccgctccgcaagcccagccagatgcgccgg
ggggcccggcgcaggagatag
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