KEGG   Actinomadura madurae: LUW76_46450
Entry
LUW76_46450       CDS       T08933                                 
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
amaz  Actinomadura madurae
Pathway
amaz00280  Valine, leucine and isoleucine degradation
amaz00640  Propanoate metabolism
amaz00785  Lipoic acid metabolism
amaz01100  Metabolic pathways
amaz01110  Biosynthesis of secondary metabolites
amaz01210  2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:amaz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    LUW76_46450
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    LUW76_46450
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    LUW76_46450
Enzymes [BR:amaz01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     LUW76_46450
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: URN01158
LinkDB
Position
complement(9789407..9790462)
AA seq 351 aa
MDTLQLLAPDGGLRDDPEWPLEVTPELCRGLYRSMRLARSLDSAALALQRQGELGLWLQS
LGQEAAQVGSITALRDTDHVFPSYREHAAALCRGITPAELLVQWRGNRHSGWDPARYRFH
IYTLVLAAQLPHATGYAMGVQRDGADEIVVGYFGDGAASEGEANEALNWAAAAEVPLLFF
CQNNHWAISTPVRAQMRAPLHQRARGFGLDAYRVDGNDVLAVRAMTRTVADRIRAGGGPA
LIEAVTYRMAGHSTSDDPGRYRTPSELDAWSARDPIARLETLLVRQGWIDDEQRAGVDAE
CEALAAETRAACLDLPLGDMSELFGTVLAEETPLLAGERRRFRELARSYQD
NT seq 1056 nt   +upstreamnt  +downstreamnt
atggacaccttgcaactgctcgctccggacggtggcctacgggacgatcccgaatggccc
ctcgaggtgacgccggaactgtgccgcggcctctaccggagcatgcggctggcacgcagt
ctcgacagcgcggccctggcgctccagcgtcagggcgagctcgggctatggctgcagtcc
ctggggcaggaggcggcacaggtcggttcgatcacggcgctgcgggacaccgaccatgtc
ttccccagctaccgcgaacacgcggcggcgttgtgccgcggcatcaccccggccgagctc
ctggtgcagtggcggggcaaccggcacagcggctgggacccagcgcggtaccgcttccac
atctacaccctggtgctggctgcccagctgccccacgcgacggggtacgcgatgggcgtc
cagcgtgacggcgccgacgagatcgtcgtcggctacttcggtgacggtgcggccagcgag
ggcgaggccaatgaggcgctcaactgggccgccgcggccgaggtcccgttgctgttcttc
tgccagaacaaccactgggccatctcgaccccggtccgtgcgcagatgcgtgcaccactg
caccagcgggcccgcgggttcgggctcgacgcctaccgtgtcgacggcaacgacgtcctg
gcagtgcgcgcgatgacccgcaccgtcgccgaccggatccgtgccgggggcgggccggcg
ctcatcgaggcggtgacctaccggatggccgggcacagcacctccgatgacccgggccgg
taccggaccccgagtgagctcgacgcctggagcgcccgcgacccgatcgcccggctggag
accctgctggtacggcagggctggatcgacgacgagcagcgagccggggtcgacgcggaa
tgcgaggccctggcagccgagacccgcgcggcgtgcctggacctgccgctgggcgacatg
tcggagcttttcggcacggtcctcgccgaggagacaccgctgctcgccggtgaacgccgt
cgcttccgagaactcgcacggtcctatcaggactga

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