Alteromonas macleodii Balearic Sea AD45: AMBAS45_14730
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Entry
AMBAS45_14730 CDS
T02253
Name
(GenBank) D-alanine:D-alanine-adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
amb
Alteromonas macleodii Balearic Sea AD45
Pathway
amb00300
Lysine biosynthesis
amb00550
Peptidoglycan biosynthesis
amb01100
Metabolic pathways
amb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
amb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AMBAS45_14730
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AMBAS45_14730
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AMBAS45_14730
Enzymes [BR:
amb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AMBAS45_14730
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Hydro_N_hd
DUF3157
Motif
Other DBs
NCBI-ProteinID:
AFT96409
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All DBs
Position
complement(3455725..3457134)
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AA seq
469 aa
AA seq
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MITTTLSWIAEKVNGKLLKGAADVEVSAVSTDTRTLEDGAVYLALKGPNFNGHDFISTAE
KAGASGVIASEDVATSLPVIMVEDTKEALGLLGAAVKAYVAPKTIAITGSSGKTTVKEMC
AAILERRGNVLATNGNFNNDIGVPLTLLRLEPQHEYAVMELGANHMGEIAYTTNLVKPDV
ATIVNAAASHLEGFGSLLGVARAKSEIFKGLGSDGVAVVNVDSQFAEFWQGKLKQTKTLT
FSPQQKNDADFRAEDITIGLDGCAAFHLVCPQGDMSIQLTIPGVHNVGNALVAAALTLQV
GATLENVRDGLLAMKQVSGRLNIKQLTEQVRLLDDTYNANVASVNAAIDTLSSFSGIRVL
VLGDMKELGEKARFYHEQVGEYAKQKGINYLYTMGVLSQSASAVFNENGGHFSDVESLLA
AMESDLLVQQRDISILVKGSRSSRMERVVEAVEASALGKHDSRRERIAC
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgataacaacaacgctgtcatggatagccgaaaaggttaatgggaaattattaaaaggc
gctgctgacgttgaagtgtctgcagtaagtaccgatacacgcaccctagaagatggcgca
gtttacttggccttgaaaggtccgaattttaacggccatgattttatttcaacggcagag
aaagcgggagcaagtggggttattgccagtgaagacgtagcaacctcgttacctgtcatt
atggttgaagataccaaagaagcacttggtttattaggtgcggcagtaaaagcttatgtg
gcgcccaaaacgattgcgattaccggaagcagtggcaaaaccaccgtaaaggaaatgtgt
gccgctattttggagcgaagaggcaatgtattagccacaaacggtaacttcaataatgat
atcggtgtgccgctaacccttttacgcctggagcctcagcatgaatacgcggttatggag
ttaggcgcaaatcacatgggtgaaatcgcctataccacgaaccttgttaagccggacgtc
gcgactatcgtaaacgccgccgcttctcatctagaaggctttggcagcttgctaggcgtg
gcgcgcgccaaaagcgaaattttcaaaggcttaggcagtgacggcgtggcggtagtcaat
gttgatagtcagtttgctgaattttggcagggcaaacttaaacagaccaaaacgctaacg
ttttcgccccagcagaaaaacgatgctgattttagagcagaagatatcaccattgggcta
gatgggtgcgccgcattccacttggtttgcccgcaaggagatatgtctattcagcttact
attcctggcgttcacaacgtggggaatgcccttgtcgctgcggcactaacgctgcaagtt
ggcgccacactagaaaacgtgcgcgacggcttacttgccatgaagcaagttagcggccgc
ttgaatataaaacagcttaccgaacaggttcgcctgttagatgacacctacaacgccaac
gtggcgtctgttaatgcggcaattgatacgctaagtagcttttcaggtatccgcgttctt
gttctaggcgacatgaaagagttgggtgaaaaagcgcgtttttatcacgagcaggttggg
gaatacgctaaacaaaaaggaattaattacctgtataccatgggtgttttgagtcaatca
gccagtgctgtgtttaatgaaaatggtggccatttcagcgatgttgaaagtttgttggcc
gcaatggagagtgatttgttagtgcagcagcgcgatatttcaattttagttaaaggttca
cgcagttccagaatggaacgtgtggtagaggcggtagaggcctctgcgctgggaaagcac
gatagccgtcgggagcgaatagcatgttaa
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