Alteromonas mediterranea DE: MADE_1009900
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Entry
MADE_1009900 CDS
T00747
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
amc
Alteromonas mediterranea DE
Pathway
amc00280
Valine, leucine and isoleucine degradation
amc00640
Propanoate metabolism
amc00785
Lipoic acid metabolism
amc01100
Metabolic pathways
amc01110
Biosynthesis of secondary metabolites
amc01210
2-Oxocarboxylic acid metabolism
Module
amc_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MADE_1009900
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MADE_1009900
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MADE_1009900
Enzymes [BR:
amc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MADE_1009900
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Motif
Pfam:
E1_dh
DXP_synthase_N
AAA_7
YuA_Gp49
Motif
Other DBs
NCBI-ProteinID:
AEA98118
UniProt:
F2GCR2
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All DBs
Position
2244643..2245830
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AA seq
395 aa
AA seq
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MKDRNHLAEVKTTNKVEIISKGVVDIPMLQVLSEQGELIKNAQEPNIDKEEALKIFNTMH
YIRVLDERMVGAQRQGRISFYLASTGEEAASVASAAALSNDDMIMSQYREQGALAYRGYT
TDQFMNQMFSNKDDPNKGRQMPIHYGDKTLNFMTISSPLGTQIPQASGYAYGQKMSGKDV
VTICYFGEGAASEGDFHAGLNMAAVLNCPVIFFCRNNGYAISTPAEEQFAGDGIASRGLG
YGVKTIRVDGNDALAIYAATKEARRIAIEEKCPVLIEAMTYRLAAHSTSDDPTGYRSREE
EDKWRAKDPIARMAKWLESKGWYNEADNQKRVEKARQDVLAAMKNCEKTDICAVEDIVED
VYDTPPWHLKEQINELKSHIKKYPKMYPKTAGRVK
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
gtgaaagacagaaaccatttggccgaagtaaaaacaacaaataaggtcgagattatttct
aaaggggtggttgatatccctatgttgcaggttctttctgaacagggagaacttattaaa
aacgcccaagagcctaacatcgacaaggaagaggcattaaaaatttttaataccatgcat
tacatccgagtattagatgaacgcatggtaggtgcacagcgccaaggtcgtattagtttc
tatctcgccagtacgggtgaagaggcggcttcggtagcgagtgcggctgcgctttcaaat
gatgacatgatcatgtctcaataccgcgaacagggtgcgcttgcctatcgcggttacact
acagatcagttcatgaatcaaatgttcagcaataaagacgacccaaataagggacgtcaa
atgcctatccattacggagacaaaacccttaatttcatgacaatttcttcgcccctaggg
acgcagattccccaagcatccggttatgcttacgggcaaaaaatgtcgggtaaagatgtt
gtcactatatgttacttcggtgaaggtgctgcatcagagggagattttcacgcggggtta
aatatggctgcggtacttaattgcccggttatattcttctgccgaaataacggctacgcc
atttcaacaccagcagaagagcagtttgctggcgacggtattgcgtcaagagggctaggc
tatggagtaaaaaccattcgcgtagatggaaacgatgctcttgcgatctatgcggcaacc
aaagaagcccgtcgcatcgctatagaagaaaaatgccctgtacttatcgaagcaatgaca
tatcgcttagctgcacactctacgtcggatgacccgacagggtatcgctctcgtgaagaa
gaagacaaatggcgagccaaagaccctattgctcgaatggcgaaatggttagagagcaaa
gggtggtacaacgaagccgacaatcaaaaacgcgtagagaaagcgcgtcaagatgtattg
gctgcaatgaaaaactgcgagaaaaccgatatatgtgccgttgaggacattgttgaagac
gtgtatgacacaccaccttggcacctaaaagaacaaataaacgagcttaagtcacatatc
aaaaagtacccgaagatgtaccctaaaaccgcagggagagtgaagtaa
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