Alteromonas mediterranea DE: MADE_1015480
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Entry
MADE_1015480 CDS
T00747
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
amc
Alteromonas mediterranea DE
Pathway
amc00260
Glycine, serine and threonine metabolism
amc00261
Monobactam biosynthesis
amc00270
Cysteine and methionine metabolism
amc00300
Lysine biosynthesis
amc01100
Metabolic pathways
amc01110
Biosynthesis of secondary metabolites
amc01120
Microbial metabolism in diverse environments
amc01230
Biosynthesis of amino acids
Module
amc_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
amc00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MADE_1015480 (thrA)
00270 Cysteine and methionine metabolism
MADE_1015480 (thrA)
00300 Lysine biosynthesis
MADE_1015480 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
MADE_1015480 (thrA)
Enzymes [BR:
amc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
MADE_1015480 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
MADE_1015480 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AEA99228
UniProt:
F2GD92
LinkDB
All DBs
Position
complement(3427955..3430420)
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AA seq
821 aa
AA seq
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MKVLKFGGSSLADAPRYMRVMEISTATHQTDGAAVVLSAPKGVTNALSLLCEQAAAGEDF
QPLFTKLNDTVTGIANNLNEELDGFAHASVVDFINSHLSVLKQHLEGIKLLGVAPDNVSA
GILSIGEYISVTLFSAMLSAKGIANRVIDPVKYVLADGEYLDSIADVSLSKARFSDVPND
GSEFLIMPGFVAANEAGEKVTLGRNGSDYSAAILAACIDASCCEIWTDVDGVYNADPNQV
EGAVLLDKLTYQEAMELSYFGAKVLHPKTIGPIAQHHIPCLIRNTLNPAAPGTLISNEKS
EVWTSVKGISQLDNVTMFNVAGPGLKGMVGMASRVFEVMSNANISISLITQSSSEYSISF
CIQSKDAQRALTLLEDAFALELQNQLLDPIEVRHDLAIVTLVGDGMRQTKGLAARFFNSL
AQARVNNVAIAQGSSERSISTVIESKRAKKAVKVIHQNFFSDRHTIDVFLVGCGNVGTEL
LGQIEKQQPALLKRNIQLRVYGIANSRKLLLNSQGIDLSGDWSAALDSASEGLSVERLHQ
FANDNSLVNPVIVDCTSHEAIANQYVDMMESGFHVVTPNKKANTSAMAYYRKLRKTALST
NRQYLYETTVGAGLPVIDNLQKLFSAGDVLHRFEGILSGSLSYVFGKLDEGMSLSQATQT
AKDNGFTEPDPRDDLSGMDVARKLLIMAREADLELELSDIEIESVLPAGFAEDCSIDEFM
QQLPELDAAINEKVEAAKAEGKVLRYIGSIEDGKCKVSIQAVPASNPLSQVKDGENALAI
NSDYYSPIPYVIRGYGAGGTVTAAGVFADILRTMPWKQMAH
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtcttaaagtttgggggttcttctctagccgatgcaccgcgatacatgcgcgtt
atggaaattagcacggcaacccaccaaaccgacggtgctgcggttgtactctctgcccct
aagggggtaacgaacgcgctttcactattgtgtgaacaagcagccgcgggtgaagatttc
caaccgttattcactaaactgaacgacacggttaccggcattgccaacaaccttaacgaa
gaactcgacggctttgcccacgcaagcgtggtagatttcatcaacagtcacctcagtgta
ttaaagcagcaccttgaaggcataaagttgcttggcgtagcgccagataatgtttcagcg
ggtatcctaagcattggtgaatatatttcggttacgcttttcagcgccatgctttcagcg
aagggcatcgctaaccgcgttatcgacccggtaaaatatgtgcttgccgatggcgaatac
ctagacagcattgccgatgtgtcgctaagtaaggcgcgtttttcagacgtaccaaacgat
ggcagtgagttcttaataatgccgggtttcgtcgccgctaatgaagcgggcgaaaaagta
acgctgggacgcaacggttcagattattccgcagcaattttagcggcgtgtatcgacgca
agctgttgcgagatttggacagacgtagatggtgtttacaatgctgacccgaaccaagta
gaaggtgcggtactgcttgataaattgacttatcaagaagccatggaactgtcttatttt
ggcgctaaagtacttcacccgaaaaccattggccctatcgctcaacatcacatcccgtgt
ttaatccgcaatacgcttaatccagcggcgccgggtacgcttatcagcaacgaaaaaagt
gaagtatggacgtcggttaaaggtatttcacagcttgataacgttactatgtttaacgtt
gcaggccctggtcttaaaggcatggtaggcatggcaagtcgcgtgtttgaagtcatgtcg
aatgcgaatatctctatcagtttaattactcagtcttcctctgagtactcaatcagtttc
tgtattcaaagcaaggacgcccagcgtgcgttaaccttacttgaagatgcgtttgcacta
gagttacaaaatcagctgcttgatccaatcgaagtgcgtcatgatcttgccattgttacc
ttagtgggtgacggtatgcgtcaaaccaaaggcttggcggcccgtttctttaactcgctt
gcgcaagcgagagttaacaacgtagccatcgcgcagggctcttctgagcgctcaatctct
acggttattgaaagcaagcgtgcgaaaaaagcggtaaaagtcattcatcagaattttttc
tctgaccgtcataccatagacgtattcctagtagggtgtggcaacgtggggactgagctg
ctagggcagattgaaaagcagcagccggcactgttaaagcgcaatattcagctgcgtgtt
tacggtattgccaatagccgtaagctactgttaaacagccaaggtatagatttaagcggt
gactggagcgcagcacttgattcagcgagcgaagggttgagcgttgagcgcttacaccag
tttgctaatgacaacagcttagtgaacccagttattgttgactgcaccagccatgaagct
attgccaatcagtacgttgatatgatggaaagtggtttccacgtagtgacgccgaacaaa
aaggcgaataccagcgccatggcttattaccgtaagctgcgcaaaacggcactttctact
aaccgtcaatacctttatgagacgacagtgggcgcaggccttccggttattgataacctg
caaaagctgtttagcgccggtgacgttctgcatcgctttgaaggtattttatcaggcagc
ttgtcttacgtgttcggcaagcttgacgagggcatgagcctgtcgcaagcgacgcaaaca
gcaaaagacaatggctttaccgagccagatcctcgcgatgatttaagcggtatggacgta
gcgcgtaagctgcttattatggcccgcgaagccgacctagaacttgagctttccgatata
gagattgagtcagtattgccagcaggttttgctgaagattgttccattgacgaatttatg
cagcagctacctgaattagatgctgcgataaatgaaaaagtggaagcagccaaagcagaa
ggcaaagtacttcgctatatcggcagcattgaagacggtaagtgcaaagtaagcattcag
gctgtgccggcaagcaacccgctttcacaagtaaaagacggtgaaaacgcgctggctatc
aacagtgactactatagcccaattccttatgtgataagaggctacggcgctggtggtacg
gtgaccgcagcgggtgtgtttgcagatattttgcgtaccatgccgtggaagcaaatggcg
cactaa
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