Amycolatopsis mediterranei U32: AMED_0617
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Entry
AMED_0617 CDS
T01269
Symbol
rifA
Name
(GenBank) rifamycin polyketide synthase
KO
K15670
rifamycin polyketide synthase modules 1, 2 and 3 [EC:
6.2.1.74
]
Organism
amd
Amycolatopsis mediterranei U32
Pathway
amd01051
Biosynthesis of ansamycins
amd01052
Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:
amd00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
AMED_0617 (rifA)
01051 Biosynthesis of ansamycins
AMED_0617 (rifA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
amd01008
]
AMED_0617 (rifA)
Enzymes [BR:
amd01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.74 3-amino-5-hydroxybenzoate---[acyl-carrier protein] ligase
AMED_0617 (rifA)
Polyketide biosynthesis proteins [BR:
amd01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Rifamycin PKS
AMED_0617 (rifA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
Ketoacyl-synt_C
KR
AMP-binding
PP-binding
KAsynt_C_assoc
CurL-like_PKS_C
Thiolase_N
RhiE-like_linker
AMP-binding_C
adh_short
PKS_DE
Epimerase
PKS_DH_N
ACP_syn_III
Polysacc_synt_2
PS-DH
GDP_Man_Dehyd
NmrA
Motif
Other DBs
NCBI-ProteinID:
ADJ42437
UniProt:
A0A0H3CUX4
LinkDB
All DBs
Position
629641..643848
Genome browser
AA seq
4735 aa
AA seq
DB search
MRTDLIKPLHVALLENATRFAGKPAFADDHRTVTYGDLEARTRRLAGHLAGLGVRHGDRV
AICLGNRVSTVESYFAILRAGAVGVPLNPGSATAELEHPLTDSGATVVVTDAAQAARLRL
APHVELLVTGDDVPEGAHSYDELALSEPAEPAADDLELDEPAWMFYTSGTTGRPKGVVST
QRNCLWSVASCYVPFPGLSDQDRVLWPLPLFHSLSHIACVLSATVVGASVRIADGSSADD
VMRLIEAESSTFLAGVPTTYHHLVRAARQRGFSAPSLRIGLAGGAVLGAGLRSEFEETFG
VPLIDAYGSTETCGAITMNPPDGARVEGSCGLAVPGVDVRVVDPDTGLDVPAGEEGEVWV
SGPNVMLGYHNSPEATAAAMRDGWFRTGDLARRDDAGYFTICGRIKELIIRGGANIHPGE
VEAVLRTVDGVADAAVGGVPHDTLGEVPVAYVIPGPTGFDPAALIEKCREQLSAYKVPDR
ILEVAHIPRTASGKIRRGLLTDEPAQLRYAATEHEEQSRHADESVAAALRARLSGLDERA
QCELLEDLVRTQAADVLGQPVPDGRAFRDLGFTSLAIVELRNRLTEHTGLWLPASAVFDH
PTPAALAARVRAELLGITQAVAEPVVAADPGEPIAIVGMACRLPGGVASPEDLWRLVAER
VDAVSEFPGDRGWDLDSLIDPDRERAGTSYVGQGGFLHDAGEFDAGFFGISPREAVAMDP
QQRLLLETSWEALENAGVDPIALKGTDTGVFSGLMGQGYGSGAVAPELEGFVTTGVASSV
ASGRVSYVLGLEGPAVTVDTACSSSLVAMHLAAQALRQGECSMALAGGVTVMATPGSFVE
FSRQRALAPDGRCKAFAAAADGTGWSEGVGVVVLERLSVARERGHRILAVLRGSAVNQDG
ASNGLTAPNGLSQQRVIRRALAAAGLAPSDVDVVEAHGTGTTLGDPIEAQALLATYGQER
KQPLWLGSLKSNIGHAQAAAGVAGVIKMVQALRHETLPPTLHVDKPTLEVDWSAGAIELL
TEARAWPRNGRPRRAGVSSFGVSGTNAHLILEEAPAEEPVAAPELPVVPLVVSARSTESL
SGQAERLASLLEGDVSLTEVAGALVSRRAVLDERAVVVAGSREEAVTGLRALNTAGSGTP
GKVVWVFPGQGTQWAGMGRELLAESPVFAERIAECAAALAPWIDWSLVDVLRGEGDLGRV
DVLQPACFAVMVGLAAVWESVGVRPDAVVGHSQGEIAAACVSGALSLEDAAKVVALRSQA
IAAELSGRGGMASVALGEDDVVSRLVDGVEVAAVNGPSSVVIAGDAHALDATLEILSGEG
IRVRRVAVDYASHTRHVEDIRDTLAETLAGISAQAPAVPFYSTVTSEWVRDAGVLDGGYW
YRNLRNQVRFGAAATALLEQGHTVFVEVSAHPVTVQPLSELTGDAIGTLRREDGGLRRLL
ASMGELFVRGIDVDWTAMVPAAGWVDLPTYAFEHRHYWLEPAEPASAGDPLLGTVVSTPG
SDRLTAVAQWSRRAQPWAVDGLVPNAALVEAAIRLGDLAGTPVVGELVVDAPVVLPRRGS
REVQLIVGEPGEQRRRPIEVFSREADEPWTRHAHGTLAPAAAAVPEPAAAGDATDVTVAG
LRDADRYGIHPALLDAAVRTVVGDDLLPSVWTGVSLLASGATAVTVTPTATGLRLTDPAG
QPVLTVESVRGTPFVAEQGTTDALFRVDWPEIPLPTAETADFLPYEATSAEATLSALQAW
LADPAETRLAVVTGDCTEPGAAAIWGLVRSAQSEHPGRIVLADLDDPAVLPAVVASGEPQ
VRVRNGVASVPRLTRVTPRQDARPLDPEGTVLITGGTGTLGALTARHLVTAHGVRHLVLV
SRRGEAPELQEELTALGASVAIAACDVADRAQLEAVLRAIPAEHPLTAVIHTAGVLDDGV
VTELTPDRLATVRRPKVDAARLLDELTREADLAAFVLFSSAAGVLGNPGQAGYAAANAEL
DALARQRNSLDLPAVSIAWGYWATVSGMTEHLGDADLRRNQRIGMSGLPADEGMALLDAA
IATGGTLVAAKFDVAALRATAKAGGPVPPLLRGLAPLPRRAAAKTASLTERLAGLAETEQ
AAALLDLVRRHAAEVLGHSGAESVHSGRTFKDAGFDSLTAVELRNRLAAATGLTLSPAMI
FDYPKPPALADHLRAKLFGSAANRPAEIGTAAAEEPIAIVAMACRFPGGVHSPEDLWRLV
ADGADAVTEFPADRGWDTDRLYHEDPDHEGTTYVRHGAFLDDAAGFDAAFFGISPNEALA
MDPQQRLLLETSWELFERAAIDPTTLAGQDIGVFAGVNSHDYSMRMHRAAGVEGFRLTGG
SASVLSGRVAYHFGVEGPAVTVDTACSSSLVALHMAVQALQRGECSMALAGGVMVMGTVE
TFVEFSRQRGLAPDGRCKAFADGADGTGWSEGVGLLLVERLSEAQRRGHQVLAVVRGSAV
NSDGASNGLTAPNGPSQQRVIRKALAAAGLSTSDVDAVEAHGTGTTLGDPIEAEALLATY
GQNRETPLWLGSVKSNLGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDRPSSYVDWSAGA
VELLTEARDWVSNGHPRRAGVSSFGIGGTNAHVVLEEVAAPITTPQPEPAEFLVPVLVSA
RTAAGLRGQAGRLAAFLGDRTDVRVPDAAYALATTRAQLDHRAVVLASDRAQLCADLAAF
GSGVVTGTPVDGKLAVLFTGQGSQWAGMGRELAETFPVFRDAFEAACEAVDTHLRERPLR
EVVFDDSALLDQTMYTQGALFAVETALFRLFESWGVRPGLLAGHSIGELAAAHVSGVLDL
ADAGELVAARGRLMQALPAGGAMVAVQATEDEVAPLLDGTVCVAAVNGPDSVVLSGTEAA
VLAVADELAGRGRKTRRLAVSHAFHSPLMEPMLDDFRAVAERLTYRAGSLPVVSTLTGEL
AALDSPDYWVGQVRNAVRFSDAVTALGAQGASTFLELGPGGALAAMALGTLGGPEQSCVA
TLRKNGAEVPDVLTALAELHVRGVGVDWTTVLDEPATAVGTVLPTYAFQHQRFWVDVDET
AAVSVTPPPAEPIVDRPVQDVLELVRESAAVVLGHRDAGSFDLDRSFKDHGFDSLSAVKL
RNRLRDFTGVELPSTLIFDYPNPAVLADHLRAELLGERPAAPAPVTRDVSDEPIAIVGMS
TRLPGGADSPEELWKLVAEGRDAVSGFPVDRGWDLDGLYHPDPAHAGTSYTRSGGFLHDA
AQFDAGLFGISPREALAMDPQQRLLLETSWEALERAGVDPLSARGSDVGVFTGIVHHDYV
TRLREVPEDVQGYTMTGTASSVASGRVAYVFGFEGPAVTVDTACSSSLVAMHLAAQALRQ
GECSMALAGGATVMASPDAFLEFSRQRGLSADGRCKAYAEGADGTGWAEGVGVVVLERLS
VARERGHRVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRGALASAGLAPSDVDVVEGHG
TGTALGDPIEVQALLATYGQEREQPLWLGSLKSNLGHTQAAAGVVGVIKMIMAMRHGVMP
ATLHVDERTSQVDWSAGAIEVLTEAREWPRTGRPRRAGVSSFGASGTNAHLIIEEGPAEE
AVDEEVASVVPLVVSARSAGSLAGQAGRLAAVLENESLAGVAGALVSGRATLNERAVVIA
GSRDEAQDGLQALARGENAPGVVTGTAGKPGKVVWVFPGQGSQWMGMGRDLLDSSPVFAA
RIKECAAALEQWTDWSLLDVLRGDADLLDRVDVVQPASFAMMVGLAAVWTSLGVTPDAVL
GHSQGEIAAACVSGALSLDDAAKVVALRSQAIAGELAGRGGMASVALSEEDAVARLTPWA
NRVEVAAVNSPSSVVIAGDAQALDEALEALAGDGVRVRRVAVDYASHTRHVEAIAETLAK
TLAGIDARVPAIPFYSTVLGTWIEQAVVDAGYWYRNLRQQVRFGPSVADLAGLGHTVFVE
ISAHPVLVQPLSEISDDAVVTGSLRRDDGGLRRLLASAAELYVRGVAVDWTAAVPAAGWV
DLPTYAFDRRHFWLHEAETAEAAEGMDGEFWTAIEQSDVDSLAELLELVPEQRGALSTVV
PVLAQWRDRRRERSTAEKLRYQVTWQPLEREAAGVPGGRWLAVVPAGTTDALLKELTGQG
LDIVRLEIEEASRAQLAEQLRNVLAEHDLTGVLSLLALDGGPADAAEITASTLALVQALG
DTTTSAPLWCLTSGAVNIGIQDAVTAPAQAAVWGLGRAVALERLDRWGGLVDLPAAIDAR
TAQALLGVLNGAAGEDQLAVRRSGVYRRRLVRKPVPESATSRWEPRGTVLVTGGAEGLGR
HASVWLAQSGAERLIVTGTDGVDELTAELAEFGTTVEFCADTDRDAIAQLVADSEVTAVV
HAADIAQTSSVDDTGVADLDEVFAAKVTTAVWLDQLFEDTPLDAFVVFSSIAGIWGGGGQ
GPAGAANAVLDALVEWRRARGLKATSIAWGALDQIGIGMDEAALAQLRRRGVIPMAPPLA
VTAMVQAVAGNEKAVAVADMDWAAFIPAFTSVRPSPLFADLPEAKAILRAAQDDGEDGDT
ASSLADSLRAVPDAEQNRILLKLVRGHASTVLGHSGAEGIGPRQAFQEVGFDSLAAVNLR
NSLHAATGLRLPATLIFDYPTPEALVGYLRVELLREADDGLDGREDDLRRVLAAVPFARF
KEAGVLDTLLGLADTGTEPGTDAETTEAAPAADDAELIDALDISGLVQRALGQTS
NT seq
14208 nt
NT seq
+upstream
nt +downstream
nt
gtgcgcaccgatctcatcaagccacttcacgtcgcactcctggagaacgcgacccgcttc
gccggcaagccggccttcgccgacgaccaccggacggtcacctacggcgacctcgaggcg
cggacgcgccggctggccgggcacctggccggcctcggtgtccggcacggcgaccgggtg
gcgatctgcctcggcaaccgggtgtccactgtggagagttacttcgcgatcctgcgcgcg
ggtgccgtcggcgtgccgctcaaccccggttcggcgacggccgagctcgagcacccgctg
accgacagcggcgccacggtggtcgtcaccgacgccgcccaggcggcccggctccggctc
gcgccgcacgtcgagctgctggtgaccggcgacgacgtcccggagggcgcccactcctac
gacgaactcgccctcagcgaaccggccgagcccgccgcggacgacctcgagctcgacgag
ccggcgtggatgttctacacgtcgggcacgaccgggcggcccaagggcgtcgtgtccacg
cagcgcaactgcctctggtccgtcgcttcctgctacgtgccgttccccgggttgtcggac
caggaccgggtgctctggccgctcccgctgttccacagcctttcgcacatcgcctgcgtc
ctgtccgccaccgtggtcggggccagcgtccggatcgccgacggcagctccgccgacgac
gtgatgcggctgatcgaggcggagagctcgaccttcctggccggcgtgccgaccacctac
caccacctggtgcgggccgcccggcagcgcggtttctccgcgccgagcctgcggatcggc
ctggccgggggcgcggtcctcggcgccgggctgcgaagcgagttcgaagagaccttcggg
gtcccgctgatcgacgcctacggcagcaccgagacctgcggggcgatcaccatgaacccg
ccggacggcgcccgcgtcgagggctcgtgcggcttggccgtgccgggcgtcgacgtgcgg
gtcgtcgaccccgacaccgggctcgacgtccccgccggcgaggagggcgaggtctgggtc
agcgggccgaacgtcatgctcggctaccacaacagcccggaggcgaccgccgcggcgatg
cgggacggctggttccggaccggggacctggcccgccgcgacgacgccggttacttcacc
atctgcggccggatcaaggaactcatcatccgcggcggcgcgaacatccaccccggcgag
gtcgaggcggtcctgcgcacggtcgacggcgtcgcggacgcggcggtcggcggtgtgccg
cacgacacgctcggcgaggtgccggtcgcctacgtcatccccggaccgaccggtttcgat
cctgcggcgttgatcgagaagtgccgcgaacagctgtccgcctacaaggtgccggaccgg
atcctcgaggtcgcccacattccccggaccgcgtcgggcaagatccggcgcgggctgctg
accgacgagcccgcgcagctgcggtacgccgcgaccgaacacgaggaacagtcccggcac
gccgacgagtccgtcgcggcggcgctgcgcgcgcgactgtccggtttggacgaacgcgcc
cagtgcgagctcctggaagacctcgtccgcacccaggcggccgacgtgctggggcagccg
gtcccggacgggcgtgcgttccgcgacctcggcttcacgtcgctggccatcgtggagctg
cgcaaccggctgaccgagcacaccgggctctggctgcccgccagcgccgtcttcgaccac
cccacgccggcggcgctggccgcccgcgtccgggctgagctcctcgggatcacgcaggcc
gtcgcggagccggtcgtcgcggccgacccgggcgagccgatcgcgatcgtggggatggcc
tgccgcctgccgggtggcgtggcgtccccggaagacctgtggcggctggtggccgagcgc
gtcgacgccgtttcggagttccccggcgaccgcggctgggacctggacagcctgatcgac
ccggaccgggagcgcgccgggacgtcgtacgtcggccagggcggattcctgcacgacgcc
ggcgagttcgacgccgggttcttcgggatctcgccgcgtgaggccgtcgcgatggacccg
cagcagcggttgctgctggagacgtcgtgggaggccctcgaaaacgccggagtcgacccg
atcgcgttgaagggcaccgacaccggcgtgttctccggcctcatgggccaggggtacggg
tccggcgcggtggcgccggagctcgaaggtttcgtcaccaccggggtcgcgtcgagcgtg
gcctcgggccgggtgtcgtacgtgctgggactggaaggcccggcggtcaccgtggacacc
gcgtgttcgtcgtcgctggtcgcgatgcacctggccgcgcaggccctgcggcagggcgaa
tgctcgatggcgctcgccggcggggtcacggtgatggccacgccgggctcgttcgtcgag
ttctcccgccagcgggccctggcgcccgacgggcgctgcaaggccttcgcggcggcggcc
gacgggaccggctggtccgagggtgtcggcgtggtcgtcctcgagcggctgtccgtggcg
cgcgagcggggccaccggatcctggccgttttgcgtggcagcgcggtcaaccaggacggc
gcgtccaacgggctcaccgcgccgaacggcctctcgcagcagcgggtcatccgccgcgcg
ctggccgcggccgggctggcaccgtccgatgtggacgtcgtcgaggcgcacggcaccggg
accacgctgggtgacccgatcgaggcgcaggccctgctggcgacctacggccaggagcgg
aagcagccgttgtggctcggttcgctcaagtcgaacatcggccacgcgcaggcggccgcg
ggcgttgcgggcgtcatcaagatggtgcaggcgctgcggcacgagaccttgccgccgacg
ctgcatgtcgacaagccgactcttgaggtggactggtccgccggtgccattgaactgctg
acggaggcccgtgcgtggccgcgcaacggccgtccgcgccgggccggggtgtcgtcgttc
ggcgtcagcgggaccaacgcgcacctgatcctggaggaggcgccggccgaggagccggtc
gctgccccggaactgccggtggtgcccctggtggtgtcggcgcggagcacggagtcgctg
tccgggcaggccgagcggctggcgtccctcctcgaaggggacgtctcgctgaccgaggtg
gccggggcgctggtgtcccgccgggcggtgctggacgagcgggccgtcgtcgtggccggt
tcgcgcgaggaagccgtgaccgggctgcgggcgctgaacacggccggttcggggacgccg
ggcaaggtcgtgtgggtgttcccggggcaggggacgcagtgggccgggatgggccgtgag
ctgctggccgagtccccggtgttcgccgagcggatcgccgagtgcgcggccgcgttggcg
ccgtggatcgactggtcgctcgtcgacgtcctgcgcggcgagggcgacctgggtcgggtc
gatgtgctgcagccggcctgtttcgcggtgatggtcgggctggctgccgtctgggagtcc
gtgggggtccggccggacgccgtcgtcgggcactcgcagggtgagatcgcggctgcctgc
gtttcgggggcgttgtccctcgaggacgcggcgaaggtggtggccctgcgcagccaggcc
atcgcggcggaactgtccggccgcggcgggatggcgtcggtcgccctgggcgaggacgac
gtcgtttcgcggctggtggacggggtcgaggtcgccgccgtcaacggcccgtcgtcggtg
gtgatcgccggggatgcccatgccctcgacgcgaccctggaaatcttgtccggggaaggc
atccgggttcggcgggtggcggtggactacgcctcgcacacccggcatgtcgaggacatc
cgcgacactcttgccgaaaccttggccgggatcagtgcgcaggcgccggctgtgccgttc
tactccaccgtcacgagcgagtgggtgcgcgacgcgggggtgctggacggcggctactgg
taccggaacctgcgcaaccaggtccggttcggagcggccgcgacggccctgctcgagcag
ggccacacggtgttcgtcgaggtcagtgcgcacccggtgacggtccagcccttgagcgag
ctcaccggggacgcgatcgggacattgcggcgtgaagacggtggcctgcggcggttgctg
gcttcgatgggtgagctgttcgtccgcggcatcgacgtggactggacggcgatggtgccc
gcggccggctgggtcgacttgccgacctacgcgttcgaacaccggcactactggctcgag
cccgccgagcccgcttcggccggagacccgctgctgggcacagtcgtcagcactcccggt
tcggaccgactcaccgccgtggcgcagtggtcgcgccgggcgcagccctgggcggtggac
ggcctggtgccgaacgcggccctggtcgaggcggccatccggctcggcgacctggccggc
acccccgtcgtcggcgaactggtcgtcgacgcgccggtggtgctgccgcggcgcggcagc
cgcgaggtccagctgatcgtcggcgagcccggcgagcagcggcggcgtccgatcgaggtc
ttttcccgggaagccgacgagccgtggacgcggcacgcgcacggcacactcgctcccgcc
gccgctgcggtgccagaaccggcggcggcgggagacgccaccgacgtcaccgtggccggc
ctgcgcgacgcggaccggtacgggatccaccccgcgctgctggacgccgccgtccgcacg
gtcgtcggcgacgacctgctcccgtcggtgtggaccggcgtgtccctgctggcctccggg
gccacggccgtgaccgtgacgccgacggcgaccggcctgcggctgaccgacccggccggg
cagcccgtcctgaccgtcgaatccgtgcgcggcacgccgttcgtcgccgagcaggggacc
accgacgcgctcttccgcgtcgactggccggaaatcccgctgcccaccgccgaaaccgcg
gacttcctgccgtacgaagccacgtcggccgaggcgaccctctccgcgctccaggcctgg
ctggcagaccccgcggaaacccggctggccgtggtcaccggggactgcaccgaacccggc
gcggccgcgatctggggcctggtgcgctcggcgcagtccgaacaccccggccggatcgtg
ctggccgacctcgacgaccccgccgtgctgcccgccgtggtggcgagcggcgaaccgcag
gtgcgggtgcgcaacggcgtcgcctcggtgccgcgcttgacccgggttactccccggcag
gacgcgcggccgctcgaccccgagggcaccgtcctgatcaccggcggcaccggcacgctc
ggtgcgctgaccgcccggcacctcgtcaccgcgcacggcgtccggcacctggtgctggtc
agccgccgcggtgaggctcccgagctgcaggaagaactgaccgcactgggggcatccgtc
gccatcgccgcctgcgacgtggcagaccgggcgcagctcgaagccgtcttgcgcgcgatc
ccggccgagcacccgctcaccgccgtgatccacaccgcgggggtcctcgacgacggcgtc
gtcaccgagctgaccccggaccggctcgccaccgtgcggcggccgaaggtcgacgccgcc
cggctcctggacgagctcacccgggaggccgatctcgccgcgttcgtgctgttctcctcg
gcggcgggtgtgctgggcaaccccggccaggccgggtacgccgccgccaacgccgagctg
gatgcgttggcgcgccagcggaacagcctcgacctgcccgcggtgtccatcgcatggggc
tactgggcgacggtcagcgggatgaccgagcacctgggcgacgccgacctgcggcgcaac
cagcggatcggcatgtccgggcttcccgccgacgagggcatggcgctgctggacgccgcc
atcgccaccggtggcacgctggtcgcggccaagttcgacgtcgccgcgctgcgggcgacg
gcgaaggccggcggcccggtgccgccgctgctgcgtggcctggccccgctgccgcgccgg
gcggcggccaagaccgcgtcgctgaccgaacgcctcgccgggctggccgagaccgagcag
gccgcggccctgctcgacctggtccggcggcacgccgccgaggtgctcgggcacagcggc
gccgaatccgtccattcaggacggacgttcaaggacgccggcttcgactcgctgaccgcg
gtggaactgcggaaccgcctcgcggccgcgaccgggctcaccctgtccccggcgatgatc
ttcgactacccgaagcccccggcgctcgcggaccacctgcgcgccaagctcttcggatcg
gcggcgaaccggccggccgagatcggcaccgccgcggccgaggagccgatcgcgatcgtc
gcgatggcgtgccgcttccccggtggcgtgcacagccccgaggacctgtggcggctggtc
gccgacggcgccgacgccgtcaccgagttccccgccgaccgcggctgggacaccgaccgg
ctctaccacgaagaccccgaccacgaaggcacgacgtacgtccggcacggcgccttcctc
gacgacgccgccgggttcgacgccgccttcttcggcatctcgccgaacgaggcgctcgcc
atggacccgcagcagcggctgctgctggagacgtcctgggagctgttcgagcgggccgcg
atcgacccgaccacgctggccggccaggacatcggcgtcttcgccggcgtcaacagccac
gactacagcatgcggatgcaccgggccgccggtgtcgagggcttccggctcaccggcggt
tcggccagcgtgctctccggccgcgtcgcctaccacttcggcgtcgaaggcccggccgtc
acggtcgacacggcctgctcgtcttcgctggtcgcgctgcacatggcggtgcaggccctg
cagcgcggcgagtgctccatggcgctcgcgggcggcgtgatggtgatgggcacggtcgag
acgttcgtcgagttctcgcggcagcgcgggctggcccccgacggccgctgcaaggcgttc
gccgacggcgcggacggcaccggctggtccgagggcgtcgggctgctcctggtggagcgg
ctgtccgaggctcagcgtcgcgggcaccaggtcctcgccgtggtccgcgggtcggcggtc
aactccgacggcgcgtcgaacggcttgacggccccgaacggcccgtcccagcagcgcgtg
atccgcaaggcactggccgccgccggactgtccacatcggacgtcgacgcggtggaggcg
cacggcaccgggacgaccctgggcgacccgatcgaggccgaggcgctgctggccacctac
ggccagaaccgggaaacgccgctgtggctcgggtcggtgaagtcgaacctcgggcacacg
caggcggctgcgggtgtcgcaggcgtgatcaagatggtcatggccatgcgccacggcgtc
ctgccccggacgctgcacgtcgaccggccgtcgtcctatgtggactggtcggccggtgcg
gtcgagctgctgaccgaggcacgggactgggtgagcaacggccacccgcgccgcgcgggc
gtgtcgtcgttcggcatcggcggcaccaacgcgcacgtcgtcctcgaagaggttgccgca
ccgatcaccacgccgcagcctgagccggccgagttcctggtgccggtgctcgtctccgcg
cggacggcggcgggtctgcgcggccaggccggacggctcgccgcgttcctcggcgaccgg
accgacgtccgcgtccccgatgccgcctacgcactggccaccacgcgcgcccagctcgac
caccgggccgtcgtcctggcctccgaccgggcacagctctgcgcggaccttgccgcgttc
ggctccggcgtcgtgaccggaacgccggttgacggcaagctggccgtgctcttcaccggc
cagggcagccagtgggccgggatgggccgtgaactcgccgagacgttcccggtcttccgc
gacgccttcgaggccgcgtgcgaggccgtggacacgcacctgcgtgagcgtccgctgcgc
gaggtcgtgttcgacgacagcgcgctgctcgaccagacgatgtacacccagggcgccctg
ttcgccgtggagaccgcgttgttccggctcttcgagtcctggggtgtgcggccgggtctc
ctcgccggtcactcgatcggcgagctcgccgccgcgcacgtgtccggcgtgctggacctg
gccgacgcgggcgagctggtcgccgcgcgcggccggctgatgcaggccctgcccgcgggc
ggcgcgatggtcgccgtccaggcgaccgaggacgaagtcgcgcccctgctcgacggcacg
gtctgcgtcgccgcggtcaacggtccggactcggtggtgctctccggcaccgaagccgcc
gtgctcgccgtcgcggatgaactggctggtcgcggccgtaagacccgacggctggccgtg
agccacgccttccactcgccgctcatggaaccgatgctcgacgacttccgcgcggtcgcc
gaacgcctgacgtaccgggccggttcgctgcccgtcgtctcgacgctgaccggggaactc
gcggcgctcgacagcccggactactgggtcggccaggtgcgcaacgccgtgcggttcagc
gacgccgtcaccgcgctgggcgcccaaggcgcgtcgacgttcctcgagctcggcccgggc
ggtgcgctcgccgcgatggcgctcggcacgctcggcggacccgagcagagctgcgtcgcg
accctgcgcaagaacggcgccgaggtgcccgacgtcctcaccgcgctcgccgaactgcac
gtccggggcgtgggcgtcgactggacgaccgtgctcgacgaaccggccacggcggtcggg
accgtcctgcccacctacgcgttccagcaccagcgcttctgggtcgacgtcgacgaaaca
gcggccgtcagcgtcaccccgccgccggcggagccgatcgtggaccggccggtgcaggac
gtgctggagctggtccgggagagcgccgcggtggtgctcgggcaccgggacgccggcagt
ttcgacctcgaccggtccttcaaggaccacggcttcgactcgctcagcgcggtcaagctg
cgcaaccgtctgcgcgacttcaccggcgtggagctgcccagcaccctgatcttcgactac
ccgaacccggccgtcctcgcggaccacctgcgggccgaactgctcggcgagcgcccggcc
gcgccggccccggtgacgagggacgtctccgacgagccgatcgcgatcgtcggcatgagc
acccggctgccgggtggcgccgacagccccgaagagctgtggaagctcgtcgcggaggga
cgggacgccgtgtccggcttccccgtcgaccgcggctgggacctcgacggcctctaccac
ccggaccccgcccacgccgggacgagctacacgcgttcgggcggcttcctgcacgacgcg
gcccagttcgacgccgggctcttcgggatctcaccgcgtgaggccctggccatggacccg
cagcagcggctgctgctggagacgtcgtgggaagccttggagcgcgcgggggtcgacccg
ctgtccgcccgcggcagcgacgtcggcgtcttcaccgggatcgtccaccacgactacgtg
acgcggctgcgcgaagtgcccgaagacgtccagggctacacgatgaccggcacggcttcg
agcgtggcgtcgggccgggtggcgtacgtcttcggcttcgagggcccggcggtcaccgtg
gacaccgcgtgttcgtcgtcgctggtcgcgatgcacctggcggcgcaggcgctgcggcag
ggggagtgctcgatggccctggccggcggcgcgaccgtgatggccagcccggacgccttc
ctcgagttctcccgccagcgcggcctgtccgcggacggccggtgcaaggcgtacgcggaa
ggcgcggacggcacgggctgggccgagggcgtcggtgtcgtcgtcctcgaacggctttcg
gtggcacgcgaacgtggccaccgggtgctggcggtcctgcgcggcagcgcggtgaaccag
gacggtgcttccaacggcctgaccgccccgaacgggccgtcgcagcagcgggtgatccgc
ggcgcgctggcgagcgccgggctggcaccgtccgatgtggacgtcgtggagggccacggg
accgggaccgcgctgggtgacccgatcgaggtccaggcgctgctggccacctacgggcag
gagcgggaacagccgttgtggctcggctcgctgaagtcgaacctcgggcacacgcaggcc
gcggccggggtcgtgggcgtgatcaagatgatcatggccatgcgccacggcgtcatgccg
gccacgctgcacgtcgacgagcgcacgagccaggtcgactggtcggcgggcgcgatcgag
gtgttgaccgaggcccgggagtggccgcgcaccggacgtccgcgccgggccggggtgtcc
tccttcggcgccagcggcaccaacgcgcacctgatcatcgaggaaggtcccgccgaagag
gccgtggacgaagaggtggcctccgtggtgccgctggtcgtctccgcccgcagcgccggt
tcgctggccgggcaggccgggcgcctggccgcggtcctcgagaacgaatcgttggccggg
gtggccggtgccctggtttccggccgcgcgacgctgaacgagcgcgcggtcgtcatcgcg
ggctcccgcgacgaggcccaggacggcctgcaggcactggcccgcggcgagaacgcgccc
ggcgtcgtgaccgggacggcgggcaagccgggcaaggtcgtctgggtcttccccggccag
ggctcgcagtggatgggcatgggccgggacctcctggactcctcgccggtgttcgccgcg
cggatcaaggaatgcgctgcggcactggaacagtggaccgactggtcgctgctggacgtg
ctgcgcggcgacgccgacctgctggaccgggtcgacgtggtgcagccggccagcttcgcg
atgatggtcgggctcgccgcggtgtggacctcgctgggggtgaccccggatgcggtgctc
ggccactcccagggcgagatcgccgcggcgtgcgtgtccggcgcgctgtcgctggacgac
gcggcgaaggtggtcgcgttgcgcagccaggcgatcgcgggggagctggcgggccgcggc
gggatggcgtcggtcgcactgagcgaagaggacgcagtcgcgcggctgacgccgtgggcg
aaccgggtcgaggtggccgcggtcaacagcccgtcctcggtcgtcatcgcgggagacgcg
caggccctcgacgaagccctcgaagccctggccggcgacggtgtccgggtccggcgggtc
gcggtggactacgcctcccacacccggcacgtcgaggcgatcgccgaaaccctggccaag
accttggccgggatcgacgcgcgggttccggcgattccgttctattccaccgtcctgggc
acgtggatcgagcaggccgtcgtcgacgcgggctactggtaccggaacctgcggcagcag
gtgcggttcggcccctcggtggcggacctggccgggctggggcacacggtgttcgtggag
atcagcgcccacccggtgctggtccagccgctgagcgagatcagcgacgacgcggtggtg
accgggtcgctgcggcgggacgacgggggactgcggcgcctgctggcgtcggcggccgaa
ctgtacgtccggggcgtggccgtggactggacggcggccgtgcccgcggccggctgggtg
gacctgccgacgtacgccttcgaccgccgccacttctggctgcacgaagccgagaccgcc
gaagccgccgagggcatggacggcgagttctggacggcgatcgaacagtccgatgtggac
agcttggccgagctgctcgagctggtgccggagcagcgcggggcgctcagcaccgtcgtg
cccgtgctggcgcagtggcgggaccggcgccgcgagcgctcgaccgcggagaagctgcgc
taccaggtcacctggcagcccctggagcgcgaagccgccggcgtgccgggcgggcgctgg
ctggccgtcgtcccggccggcaccaccgacgcgctcctgaaggagctgaccggccaggga
ctcgacatcgtccggctggagatcgaggaagcttcgcgggcacagctcgccgagcagctg
cggaacgtcctggcggagcacgacctcaccggcgtgctgtcgctgctcgctctcgacggc
ggccccgcggacgcggccgagatcaccgcgtcgacgctcgcgctggtccaggccctgggc
gacaccaccacgtccgcgccgctgtggtgcctcacttccggcgcggtgaacatcggcatc
caggacgccgtgaccgcaccggcccaggcggccgtgtgggggctcggccgggccgtcgcg
ctggagcgcctcgaccggtggggcggcctggtcgacttgcccgccgcgatcgacgcccgc
acggctcaggccctgctcggcgtcctgaacggcgccgccggggaagaccagctcgcggtc
cggcgctcgggcgtctaccgcaggcggctggtccgcaagcccgtgccggagtccgcgacg
agccggtgggaaccccgcggcacggtcctggtgaccggtggggccgaaggactcggccgg
cacgcctcggtctggctcgcgcagtccggcgccgaacggctcatcgtcaccggcaccgac
ggcgtcgacgaactgacggccgagctggccgagttcggcaccacggtcgagttctgcgcc
gacaccgaccgggacgcgatcgcgcagctggtggcggactcggaggtcaccgccgtggtg
cacgccgcggacatcgcgcagaccagctccgtcgacgacaccggcgtggccgacctcgac
gaggtgttcgccgcgaaggtgaccaccgcggtgtggctggaccagctgttcgaggacacc
ccgctcgacgcgttcgtcgtgttctcctcgatcgccggcatctggggcggtggcgggcag
ggcccggcgggtgcggcgaacgccgtcctcgacgccctggtcgaatggcgccgggcccgc
ggcctcaaggcgacgtcgatcgcctggggcgcgctcgaccagatcggcatcggcatggac
gaggccgccctcgcccagctgcgccgccgcggtgtcatcccgatggcgccgccgctggcg
gtcaccgcgatggtgcaggcggtcgccggcaacgagaaggccgtggcggtggccgacatg
gactgggccgccttcatcccggcgttcacctcggtccggcccagcccgctgttcgccgat
ctgcccgaggcgaaggccatcctccgggcggcgcaggacgacggcgaagacggcgacacc
gcgtcgtcgctcgcggactccctgcgcgcggtccccgacgccgagcagaaccgcatcctg
ctgaagctggtccgcggccacgcttcgacggtgctcggccacagcggcgccgaaggcatc
ggcccgcgccaggcgttccaggaggtcggcttcgactcgctggccgcggtcaacctccgc
aacagcctgcacgcggccaccgggctgcggctgcccgcgacgctgatcttcgactacccc
accccggaggcgctggtcggctacctgcgcgtcgaactcctgcgggaggccgacgacggc
ctggacgggcgggaagacgacctccggcgagtcctcgcggccgtgccgttcgcccggttc
aaggaggcgggcgtgctggacacgctgctcggcctcgccgacaccggcaccgaaccgggc
acggacgccgagaccaccgaagcggccccggccgccgacgacgcagaactgatcgacgca
ctggacatctccggtctcgtgcaacgagccctcgggcagacgagctga
DBGET
integrated database retrieval system
