Amycolatopsis mediterranei U32: AMED_1723
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Entry
AMED_1723 CDS
T01269
Symbol
leuC
Name
(GenBank) 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
amd
Amycolatopsis mediterranei U32
Pathway
amd00290
Valine, leucine and isoleucine biosynthesis
amd00660
C5-Branched dibasic acid metabolism
amd01100
Metabolic pathways
amd01110
Biosynthesis of secondary metabolites
amd01210
2-Oxocarboxylic acid metabolism
amd01230
Biosynthesis of amino acids
Module
amd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
amd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
AMED_1723 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AMED_1723 (leuC)
Enzymes [BR:
amd01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
AMED_1723 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
AMED_1723 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
ADJ43534
UniProt:
A0A0H3D015
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All DBs
Position
1849122..1850555
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AA seq
477 aa
AA seq
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MTSPTGKARTLAEKVWESHLVRRGEGAEPDLLYIDLHLLHEVTSPQAFDGLRLAGRPLRR
PDLTIATEDHNVPTVDIELPIADPVSRTQVDTLRRNCKEFGVRLHPMGDAEQGIVHVIGP
QLGLTQPGMTVVCGDSHTSTHGAFGAIAFGIGTSEVEHVMATQTLPLRPFKTMAITVDGE
LRPGVTAKDIILAVIAKIGTGGGQGYILEYRGQAIEALSMEARMTVCNMSIEAGARAGMI
APDETTFEYLKGRPHAPQGADWDAAVENWRQLRTDDGAEFDAEVHLDASALTPFVTWGTN
PGQGLPLGAEVPDPEAIPDENDRIAAEKALSYMDLKPGTPLREIAVDTVFLGSCTNGRIE
DLRAAAEVLRGRKVADSVRMLVVPGSMRVRKAAEEEGLDQVFTEAGAEWRQAGCSMCLGM
NPDQLKPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPEDLLTAAR
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgaccagcccgaccggcaaggcccgcacactggcggagaaggtgtgggaaagccacctc
gtgcgccgaggcgaaggcgccgaaccggacctcctctacatcgacctccacctgctgcac
gaagtcaccagcccgcaggccttcgacggcctccgcctggccgggcgaccgctgcgccgc
cccgacctgaccatcgcgaccgaggaccacaacgtcccgaccgtcgacatcgagctgccc
atcgccgatccggtctcgcgcacccaggtcgacacccttcgccgcaactgcaaggagttc
ggcgtccggctgcacccgatgggtgacgccgagcaggggatcgtgcacgtcatcggcccg
cagctcggcctgacccagcccggcatgaccgtggtctgcggcgacagccacacctccacg
cacggcgcgttcggcgccatcgccttcggcatcggcacgtccgaggtcgagcacgtgatg
gcgacccagacgctgccgctgcgtccgttcaagacgatggcgatcaccgtcgacggcgag
ctgcggcccggcgtcacggcgaaggacatcatcctcgcggtgatcgcgaagatcggcacc
ggcggcggccagggctacatcctggagtaccgcggccaggccatcgaggcgctctcgatg
gaggcgcggatgaccgtctgcaacatgtcgatcgaagccggcgcccgcgccgggatgatc
gcgccggacgagacgacgttcgagtacctgaagggccgtccgcacgcaccgcagggcgcg
gactgggacgcggcggtcgagaactggcggcagctgcgcaccgacgacggcgccgagttc
gacgccgaggtgcacctcgacgcgagtgcgctgacgccgttcgtgacctggggcaccaac
cccggccagggtctcccgctgggcgccgaggtgcccgacccggaggcgatcccggacgag
aacgaccgcatcgccgctgaaaaagccctgtcctacatggacttgaagccgggcacgccg
ctgcgggagatcgccgtcgacaccgttttcctcggctcctgcaccaacggccggatcgag
gacctgcgggccgcggccgaggtgctgcgcggtcggaaagtggcggactcggtccggatg
ctggtggttcccggctcgatgcgggtccgcaaggcggccgaggaggagggcctcgaccag
gtcttcaccgaggcgggcgccgagtggcggcaggcaggctgctcgatgtgcctcggcatg
aacccggaccagctgaagccgggggagcgcagcgcgtcgacgtcgaaccgcaacttcgag
ggccggcagggcaagggcggccggacgcacctggtctcgccgctcgtggccgccgccacg
gccgtccggggcacgctgtcgtcgccggaagacctgctgaccgccgcccgctga
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