Amycolatopsis mediterranei U32: AMED_2038
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Entry
AMED_2038 CDS
T01269
Symbol
gcpE
Name
(GenBank) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
KO
K03526
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:
1.17.7.1
1.17.7.3
]
Organism
amd
Amycolatopsis mediterranei U32
Pathway
amd00900
Terpenoid backbone biosynthesis
amd01100
Metabolic pathways
amd01110
Biosynthesis of secondary metabolites
Module
amd_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
amd00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
AMED_2038 (gcpE)
Enzymes [BR:
amd01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.7 With an iron-sulfur protein as acceptor
1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
AMED_2038 (gcpE)
1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
AMED_2038 (gcpE)
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Motif
Pfam:
GcpE
Asp_Glu_race
Zn_ribbon_9
Motif
Other DBs
NCBI-ProteinID:
ADJ43845
UniProt:
A0A0H3D0J4
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All DBs
Position
2181888..2183057
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AA seq
389 aa
AA seq
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MGTLEAVTVALGMPALPPPVLSERRKTRQLQVGSVGVGSDHPISVQSMTTTLTSDVNATL
QQIAELTAAGCDIVRVACPSADDAEALPAIAKKSQIPVIADIHFQPKYVFAAIEAGCAAV
RVNPGNIRKFDDQVKEIAQAAKDHGTPIRIGVNAGSLDKRIMDKYGKATPEALAESALWE
ASLFAEHDFHDIKISVKHNDPVVMVRAYELLAEQCDYPLHLGVTEAGPAFQGTIKSAVAF
GALLRQGIGDTIRVSLSAPPVEEVKVGIQILQSLNLKQRKLEIVSCPSCGRAQVDVYTLA
EQVTAGLEGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEHAI
VETLIEEAMRIAEEAGESLGEGAPVVTAG
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
gtgggtacgctggaagccgtgaccgtcgcactcggtatgcccgccctgcccccgcccgtc
ctgtccgagcgccgcaagactcgccagctccaggtgggttcggtcggcgtcggcagcgac
cacccgatctccgtccagtcgatgacgacgaccctcacctccgacgtcaacgccaccctg
cagcagatcgccgagctgaccgccgcgggctgcgacatcgtccgcgtggcgtgcccgtcg
gccgacgacgccgaggcgctgccggcgatcgcgaagaagtcgcagatcccggtgatcgcc
gacatccacttccagcccaagtacgtcttcgcggcgatcgaggccggctgcgccgccgtg
cgcgtgaacccgggcaacatccggaagttcgacgaccaggtcaaggagatcgcgcaggcc
gcgaaggaccacggcacgccgatccggatcggcgtcaacgcgggttcgctcgacaagcgg
atcatggacaagtacggcaaggcgacgccggaggcgctggccgagtcggcgctgtgggag
gcgtcgctgttcgccgagcacgacttccacgacatcaagatctcggtgaagcacaacgac
ccggtggtcatggtgcgcgcctacgagctgctcgccgagcagtgcgactacccgctgcac
ctcggcgtcaccgaggccgggccggcgttccagggcacgatcaagtcggccgtcgcgttc
ggcgcgctgctgcgccagggcatcggcgacacgatccgcgtctcgctgtccgcgccgccg
gtcgaagaggtcaaggtcggcatccagatcctgcagtcgctgaacctcaagcagcgcaag
ctggaaatcgtgtcgtgcccgtcgtgcgggcgcgcgcaggtggacgtctacacgctggcc
gagcaggtcacggccgggctcgagggcatggagatcccgctgcgcgtcgccgtcatgggc
tgcgtcgtgaacggcccgggtgaggcccgcgaggccgacctgggtgtggcgtcgggcaac
ggcaagggccagatcttcgtcaagggcgaggtcatcaagaccgtgccggagcacgcgatc
gtcgagacgctcatcgaagaggccatgcgcatcgccgaagaggcgggcgagtccttgggt
gagggcgcgccggtggtcaccgctggctga
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