Amycolatopsis mediterranei U32: AMED_3102
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Entry
AMED_3102 CDS
T01269
Name
(GenBank) non-ribosomal peptide synthetase
Organism
amd
Amycolatopsis mediterranei U32
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Condensation
AMP-binding
PP-binding
AMP-binding_C
PapA_C
Motif
Other DBs
NCBI-ProteinID:
ADJ44893
UniProt:
A0A0H3D5R8
LinkDB
All DBs
Position
3311395..3329322
Genome browser
AA seq
5975 aa
AA seq
DB search
MPRYDVSVPAADDDRSTLAGLVQAQAARTPAEPALTGADGTLTYATVNARANRLARLLIR
HGAGPEEVVALVLPRSADLVVAQLATAKAGAAFLPVDPDQPAERLAFVLADAKPVLVVGR
GNAKATLDLGEPGLLDGLADTDPTDADRTRPLHLDHPAYLIYTSGSTGVPKGVLVTHRGL
AGFFAAMREQYDVRPGDRVLEFSSPSFDASILELGMALPAGAALVVPPPGPLLGDRLADV
LAEHKITHALIPPVALATLSAEHAAGLPDFRTVIVGGDACPPELVRTWAPGRRMINSYGP
TEFTVVATWSDPLVPGGTPPIGHPLPEATAYVLDEALRPAATGELYLAGPELARGYLDRP
GLTASRFVADPFGEPGARMYRTGDVVRRTAGGELEFAGRTDHQVKIRGFRIEPGEIEALL
REQEGVREAVVVAREDQPGVKRLVAYVAGDADPADLRAAAADRLPPYMVPAAFVPLAAMP
LTHHGKLDRDALPEPDWAAQVRAAHTAPRTPAERALAEIWADVLGVPDIGVDADFFELGG
DSILGAQALARIRARFGAELSPRVVFDARTIAKLAELLPARSSAPAGRIEPVAHDAVVPL
SPVQRRLWVLDQQNPGSTEYNAGVGLTLSGPLDREALLAALDGLAARHESLRTTFPTVDG
EGVQVVAEEGTIPLREADAEADLDAQLAAELDRPFDLAAGPLTRATLIRRGPDEHLLLLC
QHHIITDGWSVGLLVDEFATLYAGEKPAPLDIGYRDYSRWHHDRLTGPLRERQLAYWREQ
LTGLEPLDLPTDRPRPPVRAGEGAIRRYALPAELAGRLAELGHDTGATLFTTLTALVQVL
LARYTGQDDVAVGTAVSGRDHDQLERLAGFFVNTLVLRSAVDPAQPFDAFLDRVKETTLA
AFAAAEVPFDQVVDDLRPARDPSRTPLVQVLLVLQQDLVRPREAGALRLGEHDLPRPRAR
FDLVLEFQPQGRSVAIEYDTALFDAATIDRFAGHLRVLAEAVVAEPHRPVAELPILGDAE
LAQLAELSRGPVLEAPEATLPQLFEAQAARTPDAVAVVCEDRSLTYAELDEQATRLARIL
AERGAGPERFVAVSLPRTERILVALLGVLKSGAAYLPVDPAYPADRQELILDDAGPALLL
TPDGRGPGSVPALAFDDPALLGGVSAAPLARATNPDHPAYVIHTSGSTGRPKGVVVAHRS
AANLMAWAGTDFADVFRPGSTVVASTSLNFDVSVFEIFAPLMTGATVEIVRDVLALGEGE
HTGRPVGLVSGVPSAFAQLLAQGAVSLRPSTVVLAGEALTRHALLDIRKALPGSRIANIY
GPTESTVYATAWYHDTDRTPPIGRPIAGIRSYVLDPGMRPVPVGVPGELHLGGAGVARGY
LGRPGLTADRFVADPFGEPGARMYRTGDVVRWTHSSLSGGPGGEAPGPGRSPGCRSGELE
YLGRADDQVKIRGFRIEPGEVEAALRQHPDVTEAVVVARTDAGHQRLVAYVVPEAPAGLR
EFLGASLPAHLVPSAFVPLDRLPLNPSGKLDRRALPAPDWTGGTTRVAPRTETERLLAAI
WADALGLPEVGVEDNFFELGGDSILSIRLVSEAAKAGLRITTKDVFRHQTIAVLAAAAGT
VAPAEERPPATGEVVVTPIQHWFLDTDPADPDHFVQQLGVRLADDVDGDRLRAAVNTVVA
HHDALRLRFRKTTEGWTQFHAEPGEADVFGAEIDIERGPLVRADLDGTTLRLTVHHLVVD
GVSWRILLEDIGHAYHGRELSARTTSFQDWANRLAEHDFAGDLPYWRAVDGAQIPLDTDG
ANTVASTRTVTTRLDAELTRALLQDVPGVYRTQVNDVLLAALGGALRRWSGAGRVLVDLE
GHGREDLFDDVDLSRTVGWFTSMFPVALDAPDSDIPNADIATLLKSVKEQLRAIPARGLS
YGVLRHLAGTAPAVTPRLSFNYLGRFEVEGELYQGIERELELSQHPADVRAHAVDVVARV
AEGRLEITWFYSDQLHEEATIRTVADDLVHGLAGIAAHCAEPGAGGRTPSDFPLAGLDQA
AVDRLAGDGRDVEDIYPLTPAQAGMLFHRLTGGGRHAYLQQVTFVMSDVPDPAALGRAWQ
RVVDRTPVLRTQVVWDGLDTPVQVVHRQVTLPVEHRDWTSAPEDLDTVLAADRDAGLDLG
ELPLMRLLLARVSATEVRVVWTFHHLLLDGWSLFQVLSDVAAAHAGRTLPARPPFRDHVR
WLSEQDQPTAETYWRERLSGRPEQARLRTDRPRSPAHPVESTASLRIELPAGPLRTAAQR
LGLTLNTLVQGAWAVLLARHTGRPEVCFGTTVAGRPAELPGAGEITGMFITTLPVVADVD
ERAAAADWLRGLQDAQAEARRFDHLSLARLQSWGGEFDSLLVFENYPVTAELGLRDLRGV
ETTNYPLSVVAYPGEERLEFLFGYDPELFDAETVAGFAGHLETLLAELATRPHEPLARLR
MLTDTEQQAVLDQGNGATQDCPDTTVPALFAEQVRRTPDAVAVTGDVTLTYAELDARANR
LAHRLLALGARRDGLVGLLLGRSADVVVAELAVLKAGGAYLPLDARAPRSRLTALLDGVR
VLVTDDAGRALAEDVHSGPVVTIGESGDEPSDAPDVLLRPDNLAYVMYTSGSTGTPKGVA
VSHRAVVGLARERAFAVPAHRSVLMHSALAFDASTYELWVPLLSGGRVVVAPPGDIDADV
LRRVITTHGVTGLFITAGLFRVLAQEDPGCLRGVREVWTGGEVVRPAAVRQVSDACPGLT
VVDVYGPTETTTFATRFPLPPGEPVPDVLPIGRPLDDTAAHVLDHGLRPVPPGAVGELYL
AGTGLARGYLGQPALTAERFLADPFGAPGARMYRTGDLVRWTRGSLSGGPGGEAPGPGRS
PGCHSVLEFVGRADDQVKIRGFRVELGEIETALTAHAGVAEAVVVAAENGGSKRLVAYVV
VTGTPDLREFLLRSLPDYLVPAVFVPLEALPLNENGKVDRRALPAPDFVSGLGYREPATD
AERLLAGIWAEVLRVERVGADDNFFELGGDSILSIQVVSRARRAGLDLMPGQVFDHPTVA
ALALAATPAAPAAVADAEPVTGGMPLTPVQHWYLDPRPVHPGQFAQSVSVELPAPPDPAV
LRRALRELQLHHDALRLRFTADGPHHAPDAQDVLGATIDLETGPLLRADLSGTTLTLAAH
HLVVDGVSWRILLEDLETLLEGGELPARTTSFRDWARTLARHTADGFFDGELAHWAAIDA
DPDLPVDAAGENTYGSARSLVVRLPADVTRAVLHDVPGAYRTQVNDVLLTALGRVLGDWT
GRDRVLVDLEGHGREDLFPGIDLSRTVGWFTSIFPVELTSSRADWGEALKTTKERLRAIP
RRGIGYGALRYLAGTAPHLEPRISFNYLGRFDHGGGLGGAAHPEQTRAHQLDVVGAVVGD
ELELTWQYSAGVHTEATVRRLADALSEALTGIAAHCARPDAGGRTPSDFPLARLDQAAVD
RLAGTGRTVEDIYPLTPMQSGMVFHSLVDGAAGTYLNQVRLRLTGITDPERLARAWQSVV
ADTPVLRTRVVWDGLDEPVQVVERAVTVPVVQLDWTALDDDERAREQERFLQADRAEGFD
LTAAPLLRLAFARLPGGDVLLVWTFHHVLLDGWSAAQVFGEVCARYAGATTPGHRPPFRE
YLRWLGEQDTVAAEAHWRDQLAGLRTPTPLPFDRRPVEAHRARSAASVRVSAPADGLREL
ARRAGLTLNTIVQGAWGLVLSRYSGESDVVFGTTVSGRPADLPGVESMAGLFINTLPAPV
TVHDGHTVADWLRELQAAQARSRRFDFVSLAQLQTWAGGTTLFDSILVFENYPFDTEAVA
AHGIGLHEEGELQPTNYPLSVVVAPGERLTVTFDHDPDLFDRATIDRLAGQLLLALDRIA
AGPGLRVGELDLLTDGDRERVLRTFNDTAHPVAEATVVSRFAEQVRRTPDAPAVGDLTYA
ELDARADGLARRLIELGVGVEDRVGLLLERSADVVVAELAVLKAGAAYVPVDLRAPASRM
RLVLAEAGVSVVVTDRSDVDVHDGPVVRVDETGPAGAADVVVQPGNLAYVMYTSGSTGQP
KGVAVTHRDIVALASDRSFAGEAHRSVLLHSPQAFDASTYEVWVPLLNGGRVVVAPPGDV
DADVLREVVAGQGVTALWLTAGLFRLLAQEDPGCLRGAGEVWTGGDVVPAAAVRQVRAAC
PGLTVVDGYGPTETTTFASRYVLAPEAAVPDAMPIGQPLDNMAAYVLDEGLRPVPPGVTG
ELFVAGAGVSRGYLGRPGLTAERFVANPFGEPGARMYRTGDVVRWSGGSLSGGPGGEAPG
PGRSPGNHAAVLEFVGRADDQVKIRGFRIELGEIETALSAHPDVAEAVVVTRDRRLVAYV
VTTAGTADLRAWLQRDLPDYMVPSAFVTLDALPLSANGKVDRRALPEPAAEPMAGYVPPR
TDTERVLAEVWAEVLGVPGVGVEDNFFELGGDSILSIQVVSRARRHGLALTPRDLFAHQT
VAALAVAAGSAAVTVAEQGPVTGVAALTPIQLWFFAGHFGDPDQFTQSVRIERAEPFDVG
TLRAALATLTAHHDALRMRFTIGGQENAPAEPAKILGAGIDVARGPLLTAELLEPAVLRL
TVNHLVVDGVSWRILLEDFETAYRGGPLPPKTTSFRDWANRLAAHAQAGGFDDELPYWRE
ALAVDPALPIDTALPVDHGAAEEGTGTVTTRLDAELTRALLQDVPAAYRTQVNDVLLAAL
GRVLARWTGRDGVLIDLEGHGREDLFDDVDLSRTVGWFTSLYPVALRIDDDWGALLKSVK
EQLRAVPRRGAGFGALRYLTGTAPALQPEISFNYLGRLDGAAGSLDSSVGEGAGRAHLLD
VVGRVDRETLELTWYYSRGTHTAATVERLAAELVAALGEAVAHCAEPGAGGRTPSDFPLA
ELTQRQVDRIAGDGRGVADVHPLTPMQAGMVFHGLSQESQGVYFEQVTAVLDGVAEPRFL
AEAWQHVVDRTPVLRGSVVWEDVPEPLLVVHREARVPVTELDWRNRDREEALRELLASDR
AKPFDLAAAPLVRITLARLPGDAVQLVWTFHHVLLDGWSVFQVLSDVCTAYAALRDGTPP
ALPHRRPFGDYVTWLSGQTAEGAEEYWRRELADVTEPTPLPYDRVPAFAHESSSSTWVSR
DLDEAATGRLAAFARRERLTLNAVVQGAWALLLARHSGEDDVCFGATVSGRPAGLAGVDD
ITGIFINTLPVRVTADPAAPVAGWLRGLQTAQAESRRFEHVPLTAVQAWSGVEGGRNLFD
SLVVFENYPVTADDVAAHGVRLRDLQAMETTNYPLSIVAAPGPRLSLGLGYDPALFDEAT
IRRLAGRLEHLLEAIAEDPARPLREFDVLGAGERDQVLVTFNDTGHEVPPVTLTGLIEAQ
AARTPDAVAVLSRDERLTFAELDARADRLARLLAARGAGPERIVALALGRSVEIVVAQLA
VLKTGAAYLPVDPDYPAERIAFMLADANPVVVVTKPGTPLPVENVLVLDGSEAHSPAGPL
GRSVPLAAPAYVIYTSGSTGTPKGVVVTHAGLASFSGAEIAHFDVRPGDRVLQFSSPSFD
ASVLELCMALPAGAALVVPPPGPLLGEHLAAVLRDEGVTHALIPPVAMASVPDVELPAFR
TLVVGGEACPADLVARWAPGRRMINAYGPTETTVVATWSDPLEPGATPPIGRPIRNTRVR
VLDAALRPVPIGVAGELYVSGAGLARGYLDRPGLTATRFLADPFGAPGTRMYRTGDLARW
RADGTLEFLGRADDQVKIRGFRIEPGEIVAVLRKHAGVRDAAVVADGQRLIAYFVGDPDS
ADPGSADPGSADPGSGLREHVAAALPAHFVPAAFVRLDALPLTANGKLDRRALPAPAAPE
ESAGYAAPETETEEVLAAIWAEALDLDRVGVEDNFFALGGDSLRSLQITSMTKSAFDVEI
TPRDVLTAGTVLALAELVEERVLQDLERLAAGHDH
NT seq
17928 nt
NT seq
+upstream
nt +downstream
nt
atgccgcgatacgacgtctcggttcctgccgcggacgacgacagatccacccttgccggg
ctggtccaggcccaagccgcccgcaccccggcggaaccggcgctgaccggcgccgacggc
acgctgacctacgcgaccgtcaacgcccgcgcgaaccggctggcgcggctgctgatccgg
cacggcgccggcccggaagaggtcgtcgcgctcgtgctgccgcggtcggccgacctcgtc
gtcgcgcagctggccacggccaaggccggcgccgccttcctgcccgtcgaccccgaccag
cccgccgagcggctcgccttcgtgctcgccgacgcgaaacccgtgctcgtcgtgggcagg
gggaacgccaaagccaccctcgacctcggcgaacccggcctgctcgacggcctggccgac
accgaccccaccgacgccgatcggacgcgtccgctgcacctcgaccacccggcctacctc
atctacacgtccgggtcgaccggggtgcccaagggcgtgctcgtcacccaccgcggcctg
gccggcttcttcgccgcgatgcgggagcagtacgacgtgcggcccggcgaccgggtcctg
gagttctcctcgccgagcttcgacgcctcgatcctcgagctcggcatggcgctgccggcc
ggggcggcgctggtcgtgccgccgcccggcccgctgctgggcgaccggctcgcggacgtc
ctggccgagcacaagatcacccacgccctcatcccgccggtcgcgctggccacgctgtcc
gccgagcacgcggccgggctgccggacttccgcacggtgatcgtcggcggcgacgcctgc
ccgcccgaactggtccggacctgggcgcccggccgccggatgatcaactcctacggtccc
accgaattcaccgtcgtggccacctggagcgacccgctggtccccgggggcaccccgccc
atcggccacccgctgccggaggccaccgcgtacgtgctcgacgaggccctgcgtcccgcg
gccaccggtgagctctacctcgccggtccggaactcgcccgcgggtacctggaccggccg
gggctgaccgcgagccggttcgtggccgaccccttcggcgagcccggcgcccggatgtac
cggaccggcgacgtcgtccgccggaccgccgggggcgagctggagttcgccgggcggacc
gaccaccaggtcaagatccgcgggttccggatcgaaccgggcgaaatcgaagcactgctg
cgcgagcaggagggcgtccgcgaggcggtcgtcgtcgcccgcgaggaccagcccggcgtc
aagcgcctggtggcctacgtcgccggggacgccgatccggccgacctgcgcgccgccgcg
gccgaccggctgccgccgtacatggtcccggccgctttcgtcccgctcgcggcgatgccg
ctgacccaccacggcaagctcgaccgcgacgccctgcccgaacccgactgggccgcccag
gtccgggccgcccacaccgcgccccggacacccgccgagcgggccctcgccgagatctgg
gcggacgtgctgggcgtgccggacatcggcgtcgacgcggacttcttcgaactcggcggc
gactccatcctcggcgcgcaggcgctcgcccggatccgcgcccgcttcggggccgagctg
tccccgcgggtggtgttcgacgcccgcaccatcgcgaagctcgccgagctgctgccggct
cgatccagtgccccggccggccggatcgagcccgtcgctcacgacgccgtggtgccgctc
tcgccggtccagcgccgcctctgggtgctcgaccagcagaaccccggcagcaccgaatac
aacgccggggtcggcctcaccctctccggcccgctggaccgcgaagccctgctcgccgcg
ctggacgggctggccgcgcgccacgagtcgctgcggacgacgttcccgaccgtcgacggc
gagggcgtccaggtcgtcgccgaggaaggcaccatcccgctgcgggaagccgacgccgag
gcggacctggacgcgcagctcgcggccgaactggaccgtcccttcgacctggccgccgga
ccgctcacgcgggccacgctgatccgccgtggcccggacgagcacctgctcctgctctgc
cagcaccacatcatcaccgacggctggtccgtcggcctgctcgtcgacgagttcgccacg
ctctacgcgggggagaagcccgcgccgctggacatcggctaccgcgactactcccgctgg
caccacgaccggctgaccgggccgttgcgcgagcggcagctggcgtactggcgcgagcag
ctcaccggcctcgagcccctggacctgcccaccgaccggccccgtccgcccgtccgcgcc
ggcgagggcgcgatccgccggtacgcgctgccggcggagctggccggccggctcgccgaa
ctgggccacgacaccggcgcgacgctgttcacgacgctgaccgccctcgtccaggtgctg
ctggcccgctacaccgggcaggacgacgtcgccgtcggcaccgcggtgtccggccgcgac
cacgaccagctcgaacggctcgccggcttcttcgtcaacaccctcgtcctgcggtccgcg
gtcgatccggcccagccgttcgacgctttcctcgaccgggtcaaggaaacgacgctggcg
gccttcgccgccgccgaagtgcccttcgaccaggtcgtcgacgacctgcggccggcccgt
gacccgagccggaccccgctggtgcaggtcctgctggtgctgcagcaggacctcgtccgg
ccccgggaggcgggcgccctccgcctgggcgagcacgatctgccccgcccccgggcccgg
ttcgacctcgtgctggagttccagccgcagggccgtagcgtcgccatcgagtacgacacc
gcgctcttcgacgccgcgacgatcgaccgcttcgccgggcacctgcgcgtgctggccgaa
gcggtggtcgccgagccgcaccggccggtggccgagctgccgatcctgggcgacgccgag
ctggcccagctggccgagctgtcgcgcggaccggtgctcgaagcgccggaagccaccctg
ccgcagctgttcgaggcccaggcggcccgcacgccggacgcggtcgcggtcgtctgcgag
gaccgctcgctcacctacgccgagctcgacgagcaggccacccggctggcccggatcctg
gccgagcggggcgccgggcccgagcggttcgtcgccgtctccctgccgcgcaccgaacgg
atcctggtggcgctgctcggcgtgctcaagtccggcgccgcctacctcccggtcgatccg
gcctaccccgccgaccgccaggaactgatcctcgacgacgccggcccggccctgctgctc
accccggacggccgcggccccgggtccgtccccgcgctcgcgttcgacgacccggctctg
ctcggcggcgtctccgccgcgccgctcgcccgcgccacgaacccggaccaccccgcctac
gtgatccacacgtccggctcgaccggccgccccaagggcgtcgtggtcgcccaccgcagc
gccgcgaacctgatggcgtgggccggaaccgacttcgcggacgtcttccggcccgggtcc
accgtggtcgcttcgacgtcgctcaacttcgacgtctcggtgttcgagatcttcgcgccg
ctgatgaccggcgccaccgtcgaaatcgtgcgggacgtgctggccctcggcgaaggcgag
cacaccggccggccggtcggcctggtcagcggggtgccctcggcgttcgcccagctgctg
gcccagggcgcggtgtcgctgcgaccgtccactgtggtcttggccggtgaggcgctgacg
cggcacgcgctgctcgacatccggaaagcgttgcccggcagccggatcgccaacatctac
ggacccaccgagtccactgtgtacgcaaccgcgtggtaccacgacaccgaccgcaccccg
ccgatcggccgcccgatcgccggcatccggtcctacgtcctggatcccggcatgcggccc
gtgcccgtcggcgtgcccggcgaactgcacctcggcggcgccggggtggcccgcggctac
ctcggccggccgggcctgaccgccgaccggttcgtggccgaccccttcggcgagccgggc
gcccggatgtaccggaccggcgacgtcgtgcgctggacccacagctcgctttccgggggt
ccgggtggcgaagcccccggcccggggcgaagccccggttgtcgcagcggcgagctggag
tacctgggccgcgccgacgaccaggtcaagatccgcggcttccggatcgagcccggcgag
gtcgaagccgcgctgcggcagcacccggacgtcaccgaagcggtggtggtcgcgcgcacc
gacgccggccaccagcggctggtcgcctacgtggtgcccgaggcccccgccggcctgcgc
gagttcctcggcgcttcgctgcccgcgcacctcgtgccgtcggcgttcgtgccgctcgac
cggctgccgctcaaccccagcggcaagctcgaccggcgcgccctgcccgcccccgactgg
acgggcggcaccacccgcgtcgcgccgcgcaccgagaccgaacggctcctcgccgccatc
tgggccgatgccctcggcctgcccgaggtcggcgtcgaggacaacttcttcgagctcggc
ggcgactcgatcctcagcatccggctggtgtccgaggcggccaaggccggcctgcggatc
accaccaaggacgtcttccgccaccagacgatcgccgtgctcgccgcggcggccgggacg
gtcgcacccgccgaggagcggccgcccgcgaccggcgaagtggtcgtcacgccgatccag
cactggttcctcgacaccgatccggccgacccggaccacttcgtccagcagctgggcgtc
cggctcgccgacgacgtcgacggagaccgcctgcgcgcggcggtgaacaccgtcgtcgcc
caccacgacgccctccggctgcggttccgcaagacgaccgagggctggacgcagttccac
gccgagcccggcgaagccgacgtcttcggcgcggagatcgacatcgaacgcggcccgctg
gtgcgcgcggacctggacggcaccacgctgcgcctgaccgtgcaccacctggtggtggac
ggcgtctcctggcggatcctgctggaggacatcggccacgcctaccacgggcgcgagctg
agcgcccggacgacgtccttccaggactgggcgaaccggctcgccgagcacgacttcgcc
ggcgacctcccgtactggcgggcggtcgacggcgcccagatcccgctggacaccgacggc
gccaacacggtggcgagcacccgcacggtcaccacccggctggacgccgagctgacccgg
gcgctgctgcaggacgtcccgggcgtctaccgcacccaggtcaacgacgtgctgctggcc
gccctcggcggagccctgcgccgctggagcggcgccggccgcgtgctggtcgacctcgaa
ggccacggccgggaggacctgttcgacgacgtcgacctctcccgcacggtcggctggttc
acgtcgatgttccccgtagcgctcgacgccccggacagcgacattcccaacgctgacatt
gcgacgctgctcaagtccgtcaaggagcagctgcgcgcgatcccggcccgcggcctgtcc
tacggcgtgctgcgccacctcgccgggaccgcccccgcggtgacgccccggctcagcttc
aactacctcggccgcttcgaggtcgaaggcgagctgtaccaagggatcgagcgggaactc
gaactctcgcagcaccccgccgacgtccgcgcgcacgccgtcgacgtcgtcgcccgggtc
gccgagggccgcctggagatcacctggttctactcggaccagctgcacgaggaagccacc
atccggaccgtcgccgacgacctcgtccacgggctggccgggatcgccgcgcactgcgcc
gagccgggtgcgggcggccgcacgccgtcggacttccccctggccggcctcgaccaggcc
gcggtggaccggctcgccggcgacggccgcgacgtcgaggacatctacccgctcaccccg
gcccaggccggcatgctcttccaccggctcaccggcggcggccggcacgcctacctccag
caggtgacgttcgtgatgagcgacgtccccgacccggccgcgctcggccgcgcctggcag
cgggtggtggaccggacgccggtcctgcgcacccaggtcgtctgggacggcctcgacacg
ccggtgcaggtggtccaccggcaggtcaccctgcccgtcgagcaccgggactggacgtcc
gcaccggaggacctggacaccgtgctggcggccgaccgggacgccggcctggacctgggg
gagctcccgctgatgcggctgctgctcgcgcgcgtctcggcgaccgaagtccgcgtggtc
tggacgttccaccacctgctgctggacggctggagcctcttccaggtgctctccgacgtc
gcggcggcgcacgccgggcgcacgctgccggcccgcccgccgttccgcgaccacgtccgg
tggctgtccgaacaggaccagccgacggcggaaacctactggcgcgaaaggctttccggg
cggcccgagcaggcccgcctgcgcaccgaccgccctcggtccccagcgcacccggtcgaa
tcgacggcctcgctgcggatcgagctgcccgccgggccgctgcgcaccgccgcgcagcgc
ctcgggctcaccctcaacacgctcgtccaaggcgcctgggccgtgctgctggcccgccac
accggccggccggaggtctgcttcggcaccacggtcgccggccggcccgccgaactgccc
ggggccggggagatcaccggcatgttcatcaccacgctgccggtcgtcgccgacgtcgac
gagcgggcggccgccgcggactggctgcgcggcctccaggacgcccaggccgaagcccgg
cggttcgaccacctgtccctggcgcgcctgcagagctggggcggggagttcgacagcctg
ctcgtgttcgagaactacccggtcaccgcggagctcgggctgcgcgacctgcggggcgtg
gagacgaccaactacccgctcagcgtcgtcgcctaccccggcgaggagcgcttggagttc
ctgttcggctacgaccccgagctcttcgacgccgagacggtcgccgggttcgccgggcac
ctcgagaccctgctggccgagctcgcgacccggccgcacgagccgctcgcccggctgcgc
atgctcaccgacaccgagcagcaagccgtcctggaccaggggaacggcgccacgcaggac
tgcccggacacgaccgtgcccgccctgttcgccgagcaggtgcgccgcactcccgacgcg
gtcgccgtcaccggcgacgtaaccctgacctacgcggagctggacgcccgggcgaaccgg
ctggcccaccgcctgctcgccctcggggcgcggcgggacggcctggtcgggctgctgctc
ggccgctcggccgacgtcgtcgtcgccgaactggcggtgctcaaggccggcggcgcctac
ctgccgctggacgcccgcgcaccccgcagccggctgacggcgctgctcgacggggtccgc
gtgctggtgaccgacgacgccggccgggcgctcgccgaggacgtccacagtggaccggtg
gtgaccatcggcgaatccggtgacgagccctccgacgcgccggatgtcctgctgcggccg
gacaatctcgcgtacgtcatgtacacctcgggctcgacggggacgcccaagggggtggcc
gtcagccaccgggccgtcgtcggcctggcccgggagcgggccttcgccgtccccgcccac
cggagcgtgctcatgcactccgcgctggcgttcgacgcttcgacgtacgagctgtgggta
ccgttgctcagcggcggccgcgtggtcgtcgcgccgccgggggacatcgacgccgacgtg
ctgcgccgcgtgatcaccacgcacggggtgaccgggctgttcatcaccgcggggctgttc
cgcgtgctggcgcaggaggatcccggctgcctgcgcggcgtccgcgaggtgtggacgggc
ggcgaggtggtgcgtcccgccgcggtgcggcaggtgtcggacgcgtgcccggggctgacc
gtggtcgacgtctacggccccaccgagaccacgacgttcgccacccggttcccgctgccg
cccggcgagccggtgccggacgtgctgccgatcggacggccgctggacgacaccgcggcc
cacgtgctcgaccacgggctgcggccggtgccgccgggtgccgtcggcgagctgtacctg
gccggcaccgggctggcccgcggctacctcgggcagccggcgctgacggcggaacggttc
ctggccgacccgttcggagcgcctggcgcgcggatgtatcgcacgggcgacctcgtgcgg
tggacccgcggctcgctttccgggggtccgggtggcgaagcccccggcccggggcgaagc
cccggttgtcacagcgtgctggagttcgtcggccgcgccgacgaccaggtgaagatccgc
ggcttccgcgtcgagctcggcgagatcgagacggcgctgaccgcccacgcgggcgtggcc
gaagccgtcgtcgtcgcggccgaaaacggcgggtccaagcggctcgtggcctacgtcgtc
gtgaccgggacgccggacctgcgcgaattcctgctgcgctcgctgccggactacctcgtc
ccggccgtgttcgtgccgctcgaagccctgccgctgaacgaaaacggcaaggtcgaccgc
cgggcgctgcccgcgcccgacttcgtctccgggctcgggtaccgcgagcccgccacggac
gccgagcggctgctcgccggcatctgggccgaggtgctgcgggtggagcgggtcggcgcc
gacgacaacttcttcgagctcggcggcgactcgatcctgagcatccaggtggtctcccgg
gcccgccgggccggcctcgacctgatgcccggccaggtcttcgaccacccgaccgtcgcc
gcgctcgccctcgccgccaccccggccgcgcccgcggccgtcgccgacgccgaaccggtc
accggcgggatgccgctgacgccggtgcagcactggtacctcgacccgcggccggtgcac
cccgggcagttcgcccagtccgtctcggtggaactgccggccccgccggacccggcggtg
ctgcgccgcgcgctgcgcgagctccagctgcaccacgacgccctgcggctgcggttcacc
gccgacggcccgcaccacgcgccggacgcccaagacgtcctcggcgccacgatcgacctc
gaaaccgggccgctgctgcgtgccgacctgtccggcacgacgctgacgctcgccgcgcac
cacctggtcgtcgacggcgtttcgtggcggatcctcctggaggacctggaaaccctgctc
gaaggcggcgaactgccggcccggacgacatccttccgcgactgggcccgcaccctggcc
cgccacacggccgacggcttcttcgacggcgaactcgcccactgggcggcgatcgacgcc
gacccggacctgccggtcgacgcggcgggcgaaaacacctacggctcggcccgctcgctg
gtcgtgcggctgcccgcggacgtgacccgcgcggtgctgcacgacgtgccgggggcgtac
cggacgcaggtcaacgacgtcctgctgaccgcgctcggccgcgtgctgggcgactggacc
ggccgcgaccgcgtgctggtcgacctcgaaggccacgggcgcgaagacctgttccccggg
atcgacctctcccgcacggtcggctggttcacctcgatcttcccggtcgagctgacctcg
tcccgggcggactggggcgaggccctgaagacgacgaaggaacggctgcgggcgattccc
cgccgggggatcggctacggcgccctgcgctacctcgccggtaccgccccgcacctcgaa
ccgcggatcagcttcaactacctgggccgcttcgaccacggcggcggcctgggcggcgcc
gcgcaccccgagcagacccgcgcgcaccagctcgacgtcgtcggcgcggtcgtcggcgac
gagctggaactgacctggcagtactcggcgggcgtgcacaccgaggccaccgtccgccgg
ctggccgacgccctctccgaagcgctcaccgggatcgccgcgcactgcgcccggccggac
gccggcggccgcacgccgtcggacttcccgctggcccgcctcgaccaggccgcggtggac
cgcctcgccggcaccggccggacggtcgaggacatctacccgctcaccccgatgcagtcg
ggcatggtcttccacagccttgtcgacggcgcggccgggacctacctcaaccaggtgcgg
ctgcggctgaccggcatcaccgaccccgagcgcctcgcccgggcgtggcagtcggtcgtc
gcggacacgccggtgctgcgcacccgcgtcgtctgggacgggctcgacgagcccgtgcag
gtcgtcgagcgggccgtcacggtcccggtcgtccagctcgactggacggcgctggacgac
gacgagcgggcccgcgagcaggagcggttcctccaggctgatcgcgcggagggcttcgac
ctgacggccgcgccgctgctgcggctggcgttcgcccggctgcccggcggcgacgtcctg
ctggtgtggacgttccaccacgtgctgctcgacggctggagcgccgcgcaggtgttcggc
gaggtgtgcgcccggtacgcgggcgccacgacgccggggcaccgcccgccgttccgcgag
tacctgcgctggctcggcgagcaggacaccgtggccgccgaagcccactggcgcgaccag
ctggccgggctgcggacgccgaccccgctgccgttcgaccgccgtccggtcgaggcccac
cgcgcccggtccgccgcgtcggtccgggtgtcggcacccgccgacggcctgcgggagctg
gcgcgccgcgccggcctgacgctcaacacgatcgtgcagggtgcctgggggctcgtgctt
tcccgctacagcggggaatccgacgtcgtcttcggcaccaccgtgtccggccggccggcc
gacctgccgggcgtcgagtcgatggccgggctgttcatcaacaccctgcccgcaccggtg
accgtccacgacggacacaccgtggcggactggctgcgcgagctgcaggcggcccaggcg
cgctcgcgccggttcgacttcgtgtcgctggcccagctgcagacctgggcgggcggcacc
acgctgttcgacagcatcctcgtcttcgagaactacccgttcgacaccgaagccgtggcc
gcgcacgggatcggcctgcacgaggaaggcgagctgcagccgaccaactacccgctcagc
gtcgtcgtcgcgcccggcgagcggctgacggtgaccttcgaccacgacccggacctgttc
gaccgggccaccatcgaccggctggccgggcagctgctgctcgccctcgaccgcatcgcc
gcgggccccggcctgcgggtcggcgagctcgacctgctgaccgacggcgaccgcgagcgc
gtgctgcggacgttcaacgacaccgcgcacccggtggccgaggccaccgtggtgagccgg
ttcgccgagcaggtccgccggacgccggacgccccggcggtcggcgacctgacctacgcg
gagctcgacgcccgtgccgacgggctcgcccgccggctgatcgagctgggtgtgggcgtc
gaggaccgggtgggcctgctgctggagcggtcggccgacgtcgtcgtcgccgagctggcg
gtgctcaaggccggggccgcgtacgtgccggtcgacctgcgcgcgccggcgagccggatg
cgcctggtgctggccgaagcgggcgtctccgtggtcgtcaccgatcggtccgatgtggac
gtccatgatggacccgtcgtgcgggtggacgagaccggcccggccggtgcggccgatgtc
gtggtgcagccggggaatctggcgtacgtgatgtacacgtccgggtcgacgggtcagccc
aagggcgtggcggtgacccaccgcgacatcgtggctctcgcgtcggaccggtcgttcgcg
ggcgaggcgcaccgcagcgtgctgctgcactcgccgcaggcgttcgacgcctcgacgtac
gaggtgtgggtgccgctgctcaacggcggccgggtggtcgtcgcgccgccgggagacgtc
gacgccgacgtcctgcgcgaggtcgtcgcggggcagggtgtcaccgcgctctggctgacc
gccgggttgttccgcctgctggcgcaggaggatcccggctgcctgcgcggcgccggcgag
gtgtggaccggcggcgacgtcgtccccgccgccgccgtccgccaggtgcgggcggcctgc
ccggggctgaccgtcgtcgacggctacggccccaccgagacgaccaccttcgccagccgg
tacgtcctggcccccgaagccgcggtcccggacgcgatgccgatcgggcagccgctggac
aacatggccgcctacgtcctcgacgaggggctgcggccggtcccgccgggcgtgacgggg
gagctgttcgtcgccggcgccggcgtgtcccgcggctacctcggccggccggggctgacc
gcggaacgtttcgtggccaaccccttcggcgagccgggcgcgcggatgtaccgcactggc
gacgtggtccgctggtccggtggctcgctttccgggggtccgggtggcgaagcccccggc
ccggggcgaagccccggtaatcacgcagccgtgctggagttcgtcggccgcgccgacgac
caggtgaagatccgcggcttccggatcgagctgggcgagatcgagacggccctgtccgcc
cacccggacgtcgccgaagcggtcgtcgtcacccgcgaccggcggctcgtcgcctacgtc
gtcaccaccgcgggcaccgccgacctccgggcgtggctgcagcgcgacctgcccgactac
atggtgccgtcggccttcgtgacgctcgacgcgcttcccctgagcgccaacggaaaggtc
gatcgccgggcgctgccggaacccgccgcggagccgatggccgggtacgtgccgccgcgc
acggacaccgaacgcgtgctcgccgaagtctgggccgaggtgctgggcgtgcccggcgtc
ggcgtcgaggacaacttcttcgaactcggcggcgactcgatcctcagcatccaggtcgtc
tcccgggcccggcggcacggcctcgcgctgaccccgcgggacctgttcgcccaccagacc
gtcgccgcgctggccgtcgcggcgggctcggccgcggtcaccgtggccgagcagggaccg
gtcaccggcgtcgccgcgctgaccccgatccagctctggttcttcgccgggcacttcggc
gatcccgaccagttcacgcagtcggtgcggatcgagcgggccgaaccgttcgacgtcggg
acgctgcgagcggcactggccacgctgaccgcgcaccatgacgccctgcggatgcggttc
accatcggcggccaggaaaacgccccggccgaaccggccaagatcctcggcgccggcatc
gacgtggcccgcgggccgctgctcaccgccgaactgctcgagcctgccgtcctgcggctg
acggtcaaccacctcgtcgtcgacggcgtttcgtggcggatcctcctggaggacttcgag
accgcctaccgcggcgggccgctgccgccgaagacgacctcgttccgcgactgggccaac
cggctcgccgcgcacgcccaggccggcggcttcgacgacgaactgccgtactggcgcgaa
gcgctcgccgtcgaccctgctttgccgatcgacactgccctcccggtcgaccacggcgcc
gccgaggagggcaccggcacggtcaccacgcgcctggacgccgagctgacgcgggcgctc
ctgcaggacgtcccggccgcctaccggacgcaggtcaacgacgtgctgctggccgcgctg
ggccgggtgctggctcgctggaccggccgcgacggcgtgctgatcgacctggagggccac
ggccgcgaggacctgttcgacgacgtcgacctgtcccgcacggtcggctggttcacctcg
ctctacccggtggcgctgcggatcgacgacgactggggtgcgctgctcaagtcggtcaag
gaacagctgcgcgcggtgccccgccgcggagcgggcttcggcgcgctgcggtacctgacc
gggaccgcgcccgcgctgcagcccgagatcagcttcaattacctgggccggctcgacggc
gccgccggcagcctcgactcttcggtcggcgaaggggccggccgggcgcacctgctcgac
gtcgtcggccgggtggaccgggaaaccctggaactgacctggtactactcgcgcggcacg
cacaccgccgccacggtggagcgcctggccgcggaactggtggccgcgctgggcgaagcc
gtcgcgcactgcgccgaacccggtgccggcggccgcaccccgagcgacttcccgctggcc
gagctgacccagcggcaggtggaccggatcgccggtgacggccgtggcgtggccgacgtc
cacccgctcacgccgatgcaggcgggcatggtcttccacgggctgtcccaggaatcccag
ggtgtctacttcgaacaggtcaccgcggtcctggacggcgtggccgagccgcggttcctg
gccgaagcgtggcagcacgtggtcgaccggacgccggtcctgcgcggcagcgtcgtctgg
gaggacgtccccgagccgctgctcgtggtccaccgcgaagcacgggtaccggtcaccgag
ctcgactggcggaatcgcgatcgcgaggaagccctgcgcgagctgctcgcgagtgaccgg
gcgaagccgttcgacctggcggccgcgccgctggtgcggatcacgctggcccggcttccg
ggcgacgccgttcagctcgtctggacgttccaccacgtgctgctggacggctggagcgtc
ttccaggtgctctccgacgtctgcaccgcctacgcggcgctgcgcgacggcacgccgccc
gcgctgccgcaccgccgcccgttcggggactacgtcacgtggctgagcggccagaccgcc
gagggcgccgaagagtactggcgccgcgagctcgccgacgtcaccgagccgacgccgctg
ccctacgaccgggtccccgcgttcgcccacgaatcgagctcatcgacctgggtcagccgc
gacctggacgaggcggcgaccggccggctggcggcgttcgcccggcgggagcggctcacc
ctcaacgccgtcgtgcagggggcctgggcgctgctgctggcccggcacagcggcgaggac
gacgtctgcttcggcgccaccgtgtccggccgcccggccgggctggccggcgtcgacgac
atcaccggcatcttcatcaacaccctgccggtgcgggtcaccgccgacccggcggccccg
gtcgccggctggctgcgcggcctgcagaccgcgcaggcggaatcacgccggttcgagcac
gtgccgctgaccgcggtgcaggcctggagcggggtcgagggcggccggaacctgttcgac
agcctcgtggtgttcgagaactacccggtcaccgccgacgatgtcgccgcgcacggggtg
cggctgcgtgacctgcaggcgatggagacgacgaactacccgctcagcatcgtggctgcg
cccggcccgcgcctgtcgctcggcctgggctacgacccggcgctgttcgacgaagcgacg
atccggcggctggccgggcggctcgaacacctcctggaagcgatcgccgaagacccggcc
cggccgctgcgggagttcgacgtcctcggtgccggcgaacgcgaccaggtcctcgtgacc
ttcaacgacaccggccacgaggtcccgccggtcaccctcaccgggctgatcgaggcccag
gcggctcgcaccccggacgccgtcgcggtgctttcccgcgacgaacggctcaccttcgcc
gaactcgacgcccgcgccgaccggctggcccggctgctggccgcgcggggtgccgggccg
gaacgaatcgtcgcgctcgccctcgggcgttcggtggagatcgtcgtcgcgcagctggcc
gtgctgaagaccggcgccgcgtacctgccggtcgacccggactacccggccgagcggatc
gcgttcatgctcgccgacgcgaacccggtcgtcgtggtgaccaagcccggaacgccgctg
ccggtggagaacgtgctcgtcctcgacggctcggaggcccacagcccggccggcccactc
ggccggtcggtgcccctggccgcgccggcgtacgtcatctacacctcgggctcgaccggc
accccgaagggcgtcgtcgtcacccacgccggtctcgcgagcttctccggggccgaaatc
gcccacttcgacgtccggcccggcgaccgcgtgctgcagttctcttcgccgagtttcgac
gcgtcggtgctggagctgtgcatggcgctgcccgccggggccgccctggtcgtgccgccg
cccgggccgctgctcggcgagcacctggccgccgtgctgcgcgacgaaggcgtcacccac
gcgctgatcccgccggtcgccatggcgagcgtgcccgacgtcgagctgcccgcgttccgg
accctggtcgtcggcggcgaggcctgcccggccgacctggtggcccgctgggcaccgggc
cgccggatgatcaacgcctacgggcccaccgaaacgacggtggtggcgacctggagcgac
cccctcgaacccggggccaccccgccgatcggccgcccgatccgcaacacccgcgtccgc
gtcctcgacgccgccctccgcccggtgccgatcggcgtcgcgggggagctgtacgtctcc
ggtgcggggctcgcccgcgggtacctcgaccggccgggcctgaccgccacgcggttcctc
gccgatccgttcggggcgccggggacgcggatgtaccgcaccggtgatctggcgcggtgg
cgcgccgacggcacgctcgagttcctgggccgcgccgacgaccaggtgaagatccgcggc
ttccggatcgagcccggcgagatcgtggcggtcctgcgcaagcacgcgggagtccgcgac
gccgccgtggtcgccgacggccagcggctgatcgcctacttcgtgggcgatccggacagc
gccgatccgggcagcgccgatccgggcagcgccgatccggggagcgggctgcgggagcac
gtcgccgcggccctgccggcccacttcgtgcccgccgcgttcgtccggctcgacgcgctt
ccgttgacggccaacggaaagctggaccggcgggcgctgcccgccccggccgcgccggag
gagagcgccgggtacgcagccccggaaaccgagaccgaagaagtcctcgcggccatctgg
gcggaggcgctcgatctcgaccgggtcggcgtcgaggacaacttcttcgccctcggcggc
gattcgctgcgcagcctgcagatcacgtcgatgacgaagtcggccttcgacgtcgaaatc
acgccaagggacgtgctcaccgccggcaccgtgctggcgctggcggagctcgtcgaagaa
cgggtcctgcaggacctcgaacggctcgccgccggccacgaccactga
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