Amycolatopsis mediterranei U32: AMED_5034
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Entry
AMED_5034 CDS
T01269
Name
(GenBank) non-ribosomal peptide synthetase
Organism
amd
Amycolatopsis mediterranei U32
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
Condensation
PP-binding
AMP-binding_C
Methyltransf_12
Methyltransf_11
Methyltransf_25
Methyltransf_23
MTS
NodS
Motif
Other DBs
NCBI-ProteinID:
ADJ46799
UniProt:
A0A0H3DB68
LinkDB
All DBs
Position
complement(5555403..5573438)
Genome browser
AA seq
6011 aa
AA seq
DB search
MSNGDAVQQQVSRLGFWRDRLASAPKELPLPVDRPYPAAPAAPATLARPVPEADELTLLA
AFTVLLSRYAGTADVLLGIGSLVPLRVDLGGSPGFADVVARVREAREAALGHEVPFADLV
AELEPEPGRGGSLLVNVGFGAATDLPLDLNLTGEGVRYRPDVLDESTVDRMLDHLGHLLA
EAAERPQWPVDRLALMAAPELHRILDDWNDTDLATPLSTLPELFAARVRANPDGIALVFE
DTELTYAELDARANRLAHVLIARGAGPERVVALAVPRSVDMIVAELAVLKAGAAYLPLDQ
DYPGERLAFMVADARPVCVVTTRALAGRFDGDVLLLDELDIGDAPATDPAAAIVPANAAY
VIYTSGSTGRPKGVVVSHAGVAKLVATQSERFGVGPHSRVLQFASPSFDVAFWDLCLGLL
SGGRLVIVPAERRVPGPELAEYAHAHGVDFMILPPALLAEFPEDCDLPRNSVLLAGTERV
SPELVRRWAPGRRMFNAYGPTEATTNSTLGLCDPEIAPGSAVPIGVPDPGTRAYVLDAHL
APVPVGVVGELYLAGSGLARGYLGRPGLTAERFVADPFGSGGRLYRTGDLVKWLPDGRLV
FLGRADDQVKIRGYRIELGEIESVLAEHPRVGQPVVIAQDGQLIAYAVPVPDRDQAAEQG
HVDEWHDVHEEMLAGSHGIEENFAGWNSSYDGSELPRAEMREWHAATIERIRALHPKRVL
EIGVGSGLILSRIAPDAETYWGVDLSESAVENVRREVAAMPELAGKVQLAARPAHDLGEL
PDFDTVIINSVAQYFPSADYLAEVVKTAAARLVPGGTIFLGDLRNLRSLRAFRTAVELHR
GRTDVAAVDQAIAREGELVLDPDFFPALARELDGFGDVDLWVKRGTAHNELTRHRYDVVL
RKAPRPAAAEEQVVAFGDLGAVERFLAAETPERLRVTAIPDARLAGELAAVRALDTGDAE
AALAALDRRDGVDPEDLYRLGERAGYRVAVTLAAEGGELEAVFSRGEDGPAYRPVRPTGT
PGSYANNPAARRETGALVASLRAHVRDRLPRYMVPSAFVILDKLPVLASGKLDRKVLPSP
ERFTAGPGRAPRNPVEQLLCEMFADVLGVPQAGPDDDFFALGGHSLLATRLIQRIRAAVG
AEVPVRAVFDAPTPAALADFLAGAVTETGRRPLGRVTERPERLPLSFAQQRLWFLHGLEG
GSATYNVPFVVGLAGELDVDALRSALADVLDRHEALRTVFPVVDGVPYQRILPEGTVELT
VREVSDVDAEVDELVRGVFDLGAGVPVRAELLTVDPRRHVLVLVVHHIAADGWSLSPLWR
DIAAAYRARLRGKAPQWTPLPVQYVDYTLWQRDLLAAEEQGQLEYWRETLEGLPDRIPLP
LDRPHPPVSAYRGGFFTFTWDAGLQAGLADLARACGASPFMVVHAGLTALLSRLGAGTDI
PIGTPIAGRTDPALDDLVGFFVNTLVLRVDTGGDPSFRELVARVRERSLDAYAHQDVPFE
RLVEALNPARSLAHHPLFQTMLAWQNTPGTGVELPGLTVTERPVGTGTAKFDLWFSFTER
ADGLRGQAEFNAEVFDRATVTGLLDRLETLLRQVAAAPDRRLGSLDVLTPAERAGLEKTW
SGAIEDVPAVTVPELFAAQVARTPDHPALVFEDEVLTYAELDAVSNRLARVLAARGAGPE
RVVALALPRSTHLVTAILAVLKTGAAYLPLDPGYPADRIAFMLEDAAPALVLAVADTAVP
GAVLLDDPANLAGVSDAPLEVVPRPENPAYVIYTSGSTGRPKGVVVPHAGIVNRLLWMQA
EYGLTPDDRVLQKTPSSFDVSVWEFLWPLITGATEVLARPDGHKDPAYLARLIRDRDITT
VHFVPSMLQVFLQEPAAAECTNLRRVLCSGEALPLDAVAQFGQVLDAELHNLYGPTEASV
DVTSWRTSTEDGSIPIGRPVWNTRTYVLDAALRPVPPGTPGELYLAGVQLARGYLGRAGL
TAERFVADPFGAPGARMYRTGDLARFRPDGVLEFLGRGDEQIKIRGFRVEPGEIAATLAA
HDDVAHAVVVAREDRPGDVRLVGYVVPADTSGSAEEETEQVGEWRELYDSMYSGDGDEFA
GWNSSYTGEPLPRAEMREWRDAIVTRIRSLRPQRVLEIGVGSGLLLTELAPHCEAYWGTD
FSAEVIATLGERVAADPALAGRVELRTGDAADVTGLPAGFFDTIVLNSVVQYFPSGTYLL
DVVRKALELLAPGGSLFVGDVRDLRQVRAFHTAVAQARGGDVEQRLLREKELLVAPEFFA
GLDGVAADIRVKRGRAVNELTQYRYDVVLRPGAAGPLPGATLTWGTDVSTVDEVAERVRD
GLRVEGVPNGRITEGVNPEDWYELGAVVTWSAAADGSVDVLFTSGDPAGAFRPGPEPLLS
YTGNPRRSHRSTALPADLRALAAERLPEHMVPSAIVVLDALPVTANGKLDRRTLPAPERS
APVSGREPRTPVERQLCELFADVLGLPRVGPDDSFFALGGHSLLATRLIARVRAALHAEL
EVRAVFETPTPAGLAGVLATARGAARPPLVPAPRPELVPLSGAQQRLWFLHHLEGASATY
NVPLIMRLEGDLDVEALRRALSDVVARHEALRTRFPQRDGVPYQDILAPGEVDLPVREVA
ELDETLTGLVRGSFDLERHVPVRAELLRLGAREHVFALVFHHIASDGWSMAPLWRDLATA
YAARGAGEAPQWTPLPVQYADYTLWHRDLLGREDDPDSVLSAQLDYWRTALDGLPDRIEL
PLDRPHPATATFRGELHTFTWDAGLHTGLAELARESGASVFMVVHAALAALLTRLGAGTD
VPIGSPIAGRTDPALDDLVGFFVNTLVLRVDTGGEPTFRELLARVRERNLDAYAHQDVPF
ERLVELLNPARSPSYHPLFQVMIAGQNNARAEVTLPGLAVTELPVTTGTSKFDLSISLTE
RDAGIAGVLEFNADVFDHAGANAILRRLEVLLRAALAEPDRPVGALDLLDGDERDRVLTE
WAGSLEPAGTETFPGMFARRVAEAPDAVALVFEDVELTYAEVNARANRLAHLLLERGAGP
ERVVALAVPRSVDMIIAELAVLKAGAAYLPIDVDYPGDRIAYMVEDAAPVCVVTTRDIEA
KLPTTLPRVLLDDAALTAMSTEDPSVVVRPENAAYVIYTSGSSGRPKGVVLQHSGVAKLV
ATQVERFGVGPHSRVLQFASPSFDVAFWDLCLGLLSGGRLVVVPAERRVAGPALTEYAHA
HGVDFMILPPALLDAMPADCDLPRDGVLLAGTERVSPELVRRWAPRRRMFNAYGPTEATT
NSTLGESDPAELADATVVPIGIPDPGTRAYVLDARLRPVPPGVVGELYLAGSGLARGYLG
RPGLTAERFVADPFGSGGRLYRTGDLVKWRPDGRLVFLGRADDQVKIRGYRIELGEIESV
LAEHPAVGQSVVVARDSRLIAYAVPSAGRDEEAERDHVGEWRELHENVFTEAASGGLEEN
FTGWNSSYDGSELPLAEMREWHAATIERIRALRPKRVLEIGVGSGLILSRIAPDAEEYRG
VDLSEQAIANLRRELAATPFASKVHLAARPAHDLGELPDFDTVIVNSVAQYFPSVGYLAE
VLRTAAAHVRPGGVLFLGDIRNLRSLRAFRTATELRHGRRDVAAVDQAIAREGELVLDPD
FFAALALDGFDDVDLWVKRGHAHNELTRHRYDVVLRKAPRPEAAEEQVVAFASVDELERV
LAARPARLRVTGVPDARLSGELAAVAALAAGDAETALSSLEDRSGVDPETLHDLGGRHGY
RAYATLTADVGELEVVFTTGEPTRIHRGRPVRAALDALGNHPAGQRDASALVAALRAHVR
DRLPQYMVPSAFVLLDRLPLLASGKLDRRALPNPDKQGTSTGRAPRTPVEEVLCGLFAEV
LDAASIGVDDDFFALGGHSLMATRLVARLRAVFGVELQVRSVFETPTVAGLAALLSTSDS
GAARPALVRVDPRPDVLPLSFAQQRLWFLHRLEGPSATYNMPTAVRLTGTLDVDALRTAL
SDVVERHEALRTVFPEIDGEARQLVLGDVTIPLPIRAVTEATLADAVSEAAATVFELEAE
IPLRAQLLRLGAREHVLVLVFHHIASDGWSTAPLWRDLATAYTARQAGDAPQWTALPVQY
ADYTLWQRDVLGEPVIEPQLAYWREALAGLPERIELPTDRPHPAEASYRGEQFAFGWDAE
LHSGLVELARTCGASVFMVVHAGLTAVLTRLGAGTDIPLGTSIAGRTDAALDDLVGFFVN
TLVLRVDTGGDPSFRELVARVRDRSLDAYAHQDVPFERLVEALNPVRSLAYHPLFQTMLA
WQNNAVADLALPGLTVAEEPVRTGTARADLTFFVGERPGHRAGIRGTAEYNTDVFDRASV
EAILERLRTLLAAVVADPDTRIGAVDLLTGVERDQLAADPAIPLPAETPAGLFAAQVTRT
PDALALVFGSERLTYAELETRATVLARALLARGAGPERVVAVALPRSVELVVALLAVLKI
GAAYLPLDLNHPAERLELMLADAAPHLVIAEDGFGDRLVRPGETGPEPAWPPISPDHPAY
VIFTSGSTGRPKAVAGTQRALANRLHWGRSALGPGVRVAKSALTFIDGSTELLGGLVAGD
PVVLADDATATDPMALAEFVRESGAQVLTVVPSLLDSFAEDASAGAFDAVTTWITSGEPL
SDVLAEKVARRWPSAKLVNLYGCSEVAGDSLAQVCGPVAIGRPIANTRTYVLDAALRPVP
PGVRGELYLAGAGLARGYLGRPALTAERFVASPFEPGERMYRTGDLVRRRPDGTLQFLGR
SDQQIKIRGFRVEPGEVEAALRAGASVARAVVIARENRLIAYVAPSGDPVALRASLAARL
PEYLVPSAIVVLPELPVNANGKLDRAALPDPQVRASGRAARTPAEQALCELFADVLGVAA
VGPDDGFFALGGHSLLATRLVSRIRALLGVEVPIRAVFDAPTPGRLAEALDPGRGRRPAL
VPAPRPDVLPLSFAQQRLWFLDRLDGLSATYNIPWAWELTGPVDTDALRAALGDVVARHE
VLRTLLVEEQGTPRQVILDRADPVLVTETAADLDERVTAAASYCFTLDAEIPIRATLVSA
GPERHVFVLLVHHIAGDGWSLPPLKRDLDTAYAARLGGERPQWTPLPVQYADYTLWQRQM
FGRADDPDSLLGRQAAFWRDTLAGLPDELALPADRPRPARSTGRGAAVPFTVPASVHNGL
RELAHRSDTSTFMVVQAVLAALLTRLGAGTDIPLGTPVAGRPDHALEDLAGFFVNTLVLR
TDTGGDPTFRQLLDRVREADLAAYAHQDLPFEHLVELLNPPRSLARHPLFQVMLAVYHSG
SEPDRLLGLDAAYRDTGLRQAKFDLSFDLVETADGIDGDLEYSLDLFDEPTARTLTERLV
RVMAAVVADPDRPLSRIDVLDPGERERILRDWGAGAPLTLPAPTVLDRLAGQVAATPDAT
ALSDASSSVTFAEFAARTDRLARWLASQGAGPEKVVALVLPRSAAVVEAIFGVFKTGAAY
LPVDPDQPLERISAILADADPALVLTSRSLASVVPGALLVEDIVDSDATLIPPSPANPAY
VLYTSGSTGKPKGVVIPHSGLVNLFHSHRETLYRPAVAAAGGRRLRVGHAWAFFFDASWQ
PQLWLLDGHEVHVVDDDTRRDPDRLAAVVRERGLDFLELTPSHFAQLAAAGVISAGRCAL
GVVGVGGEAVSQTLWETLSSMPGTQAYNLYGPTEATVDALVGRFGDADRPVIGRPVHNTR
AYVLDGGLSPVPAGVPGELYLAGAGLARGYHGRPGLTADRFVASPFEPGERMYRTGDLVR
WRPDGQLEYLGRTDDQVKIRGFRIEPGEIETALARHDDVTQALVVVREDRDKRLVAYVTP
ATADPARLREFAARSLPEYMVPAAIVPVDAFPVTPNGKLDKAALPVPDVAARGRAPETPL
EQALCEIFAEVLDVAAVGADDDLFTLGGHSMLLVVLRNRITERLGTELPIAEFFRTPTAA
GLAALSTRNPE
NT seq
18036 nt
NT seq
+upstream
nt +downstream
nt
gtgagcaacggtgacgctgtgcagcagcaggtgtcgaggctcggtttctggcgcgaccgc
ctcgcttcggcgccgaaggagctgccgctgccggtcgaccggccctatccggcggcgccc
gccgccccggcgacgctcgcccggcccgtgcccgaggccgacgagctgacgctcctcgcg
gcgttcacggtgctgttgtcccgctacgcgggaacggccgacgtcctgctcgggatcggc
tcgctggtgccgctgcgggtggatctgggcggctcgcccggatttgccgacgtcgtcgcg
cgcgtccgtgaggcgcgagaagctgcgctggggcacgaggtgcccttcgccgacctggtc
gccgagctggagccggagcccggtcgcggcgggtcgctgctcgtcaatgtcggcttcggc
gccgcgaccgacctgcccctggacctgaacctgaccggcgagggggtgcgctaccgtccc
gacgtcctcgacgagtccactgtggaccgcatgctcgaccacctcggccacctcctcgcc
gaggcggcggaacgtccacagtggccggtcgaccggctcgcgctgatggccgcgccggaa
ctgcaccggattctcgacgactggaacgacacggacctcgcgacgccgctgtccaccttg
ccggagctgttcgcggcccgggtccgggcaaacccggacgggatcgcgctggtcttcgag
gacaccgaactcacctacgccgaactcgacgcccgcgcgaaccgcctcgcccacgtcctc
atcgcccgtggcgcgggtcccgagcgggtggtcgcgctcgccgtgccgcggtcggtggac
atgatcgtcgccgaactcgcggtgctcaaggccggcgccgcgtacctgccgctggaccag
gactacccgggcgagcgcctcgcgttcatggtcgccgacgcccgcccggtgtgcgtggtc
accacccgcgcactcgccggccggttcgacggcgacgtcctgctcctcgatgagctcgac
atcggcgacgcgccggcgacggacccggccgccgcgatcgtcccggccaacgccgcctac
gtcatctacacttccggctccaccggacggcccaagggcgtcgtggtttcccacgcgggc
gtcgccaagctggtcgcgacgcagtccgagcggttcggggtgggcccgcacagccgggtg
ctgcagttcgcgtcgccgagtttcgacgtcgccttctgggacctgtgcctcggcttgctt
tccggcggccgcctggtgatcgtcccggccgaacggcgggtgcccgggccggaactggcc
gaatacgcgcacgcccacggcgtcgacttcatgatcttgccgcccgccctgctcgccgag
ttccccgaggactgcgacctgccgcggaacagcgtgctgctggcgggcactgaacgggtg
tcgccggagctggtccgccgctgggcgcccggacggcggatgttcaacgcctacggaccc
accgaggccacgaccaactcgacgctcggcctctgcgacccggagatcgcgccgggctcg
gccgtcccgatcggcgtgccggaccccggcacccgggcgtacgtcctcgacgcgcacctc
gcgccggtgccggtcggggtggtgggggagctgtatctcgcgggaagtggtctggcgcgg
gggtatctcgggcggccggggctgacggcggagcggttcgtggcggacccgttcggctcg
ggcggacggctttaccggaccggtgacctcgtgaagtggctgcccgatggccggttggtg
ttcctgggccgcgccgacgaccaggtcaagatccgcggttaccggatcgagctgggcgag
atcgagtcggtgctcgccgaacacccgcgcgtcggccagccggtcgtcattgcgcaggac
gggcagctgatcgcctacgccgtgccggtgcccgaccgcgaccaggcggccgagcagggc
cacgtcgacgaatggcacgacgtccacgaggagatgctcgccgggtcccacggcatcgaa
gagaacttcgcgggctggaactccagctacgacggctcggagctcccccgcgccgagatg
cgggagtggcacgcggcgacgatcgagcggatccgggcgctgcacccgaagcgggtgctg
gagatcggcgtcggcagcgggctgatcctctcgaggatcgccccggacgccgaaacctac
tggggtgtggacctctccgagagcgccgtcgagaacgtccggcgcgaggtcgccgccatg
cccgagctggcgggcaaggtccagctcgccgcgcggcccgcccacgacctgggcgaactg
ccggacttcgacacggtgatcatcaactccgtcgcccagtacttccccagcgcggactac
ctcgccgaagtcgtgaaaaccgccgccgcgcggctggttccgggcggcacgatcttcctc
ggcgacctccgcaacctccgttcgctgcgggcgttccggaccgccgtcgagctgcaccgc
ggccgcaccgacgtcgccgcggtggaccaggcgatcgcgcgcgaaggcgagctggtcctc
gatccggacttcttcccggcattggcccgggaactcgatggcttcggcgacgtcgacctg
tgggtcaagcgcggcaccgcgcacaacgagctgactcgccaccgctacgacgtcgtcctg
cggaaggcgccgcggccggcggcggccgaagagcaggtcgtcgcgttcggcgacctcggt
gcggtggaacggttcctggccgccgagacgccggagcggctgcgcgtcaccgcgatcccg
gacgcgcggctggcgggcgagctggccgcggtccgcgccctggacaccggcgacgccgag
gccgccctggccgccctcgaccgccgcgacggcgtcgacccggaagacctctaccggctc
ggcgagcgcgccggctatcgcgtggcggtgaccttggcggccgaaggcggcgagctggag
gccgtcttctcgaggggggaggacggccccgcctaccgcccggtgcgtccgacgggcacg
ccgggttcgtacgccaacaacccggcggcccggcgggaaaccggtgcgctggtggcgtcg
ctgcgcgcgcacgtccgggatcggctgccgcggtacatggtgccttcggcgttcgtgatc
ctcgacaagctgcccgtcctcgcctccggcaagctggaccgcaaggtcctgccgagcccc
gagcggttcaccgccggacccggccgcgcgccccgcaaccccgtcgagcagctgctgtgc
gagatgttcgccgacgtcctcggggtgccgcaggccggaccggacgacgacttcttcgcg
ctcggtgggcattcgctgctcgccacccggctgatccagcgcatccgcgcggcggtcggc
gccgaagtgccggtgcgggcggtgttcgacgctccgacgccggccgcgctcgcggacttc
ctcgccggcgccgtcaccgagaccgggcggcgcccgctcgggcgcgtcaccgagcggccg
gagcggctgccgctgtccttcgcgcagcagcgcctgtggttcctgcacgggctggaaggc
ggctcggcgacctacaacgtcccgttcgtcgtggggctcgccggcgaactcgacgtcgac
gcgctgcgttcggcgctcgccgacgtcctggaccggcacgaggccctgcggacggtcttc
ccggtcgtcgacggcgtgccgtaccagcggatcctgcccgaggggacggtggagctgacc
gtccgggaagtgtccgatgtggacgccgaagtggacgagctcgtgcgcggcgtgttcgac
ctcggtgccggggtaccggtgcgcgcggaactgctgaccgtcgacccgcggcggcacgtg
ctggtgctggtcgtgcaccacatcgccgccgacggctggtcgctgtccccgctgtggcgg
gacatcgcggcggcctaccgcgcccggctgcgcggtaaagctccacagtggacgccgctg
cccgtgcagtacgtggactacacgctctggcaacgtgatctccttgcggcggaagagcaa
ggccagctcgaatactggcgtgagacgttggaaggcttgcccgaccggatcccgcttccg
ctcgaccggccgcacccgccggtctcggcctaccgcggcgggttcttcaccttcacctgg
gacgcggggctgcaggccgggctcgccgacctcgcccgcgcctgcggggccagcccgttc
atggtcgtgcacgcgggcctgacggcgctgctgtcccggctcggcgcgggcaccgacatc
ccgatcggcaccccgatcgccggccgcaccgacccggccctggacgacctcgtcggtttc
ttcgtcaacaccctggtgctgcgcgtcgacaccggcggcgacccgtcgttccgcgaactc
gtggcccgggtgcgcgagcgcagcctcgacgcctacgcccaccaggacgtcccgttcgag
cggctggtcgaggcgctcaacccggcccggtcgctcgcccaccacccgctgttccagacc
atgctcgcctggcagaacacccccggcaccggcgtcgaactgcccggcctgaccgtgacc
gagcggcccgtcggcaccggcacggccaagttcgacctctggttctccttcaccgagcgc
gccgacggcctgcgcggccaggccgaattcaacgccgaggtgttcgaccgcgccaccgtg
accggcctcctcgaccgcctggaaaccctgctccggcaggtcgccgccgccccggaccgc
cgcctcggctccctcgacgtgctcaccccggccgagcgcgccggcctcgaaaagacctgg
tcaggtgccatcgaggacgtccccgcggtcaccgtccccgagctgttcgccgcccaggtc
gcgcgaactcccgaccacccggcgctggtgttcgaggacgaagtactcacctacgccgag
ctcgacgccgtctcgaatcgcctggcccgcgtgctggccgcgcgcggagccgggcccgag
cgtgtggtcgccctggcgctgcctcgctcgacgcacctggtcacggcgatcctcgccgtg
ctcaagacgggcgcggcctacctgccgctcgaccccggctatccggccgaccgcatcgcg
ttcatgctcgaagacgccgccccggcactcgtgctggccgtcgcggacaccgccgtcccg
ggcgccgtgctcctggacgacccggccaacctggccggcgtctcggacgcgcccctggaa
gtcgtgccgcggccggagaacccggcgtacgtcatctacacctccgggtcgacgggccgg
ccgaagggcgtggtcgtcccgcacgccgggatcgtgaaccggctgctgtggatgcaggcc
gagtacggcctcacgcccgacgaccgcgtgctgcagaagacgccgtccagcttcgatgtg
tcggtgtgggagttcctctggccgctgatcaccggcgccaccgaggtgctcgcccggccg
gacgggcacaaggaccccgcctacctcgcccggctgatccgcgaccgggacatcacgacc
gtccacttcgtcccgtcgatgctccaggtcttcctccaggagccggcggcggcggagtgc
acgaacctgcgccgggtgctgtgcagtggcgaggccctgcctctggacgccgtcgcgcag
ttcggccaggtgctggacgccgagctgcacaatctgtacggcccgaccgaagcttcggtc
gacgtgacgtcgtggcggacgtccacagaggacggttccatccccatcggacgtccggtg
tggaacacccgcacctacgtcctcgacgccgccctgcgcccggtcccgccgggtaccccc
ggcgagctgtacctggccggcgtccagctcgcccgcggctacctcggccgggccgggctc
accgccgagcggttcgtcgccgacccgttcggcgcgcccggcgcccggatgtaccgcacc
ggcgacctcgcccgcttccgccccgacggcgtcctcgagttcctcggccgcggcgacgag
cagatcaagatccgcgggttccgcgtcgaacccggggagatcgccgcgaccctggccgcg
cacgacgacgtcgcccacgccgtcgtcgtcgcccgcgaggaccgccccggcgacgtccgc
ctggtcgggtacgtcgtcccggccgacacctccggctcggccgaggaggagaccgagcag
gtcggcgagtggcgtgagctgtacgactcgatgtactccggcgacggcgacgagttcgcg
ggctggaactccagctacaccggcgagccgctcccgcgggccgagatgcgcgagtggcgc
gacgcgatcgtcacgcggatccggtccctccggccgcagcgggtcctggagatcggcgtc
ggcagcggcctgctcctgaccgagctggctccgcactgcgaggcctactggggcacggac
ttctccgccgaggtcatcgctacgctcggcgagcgggtcgcggccgatcccgcgcttgcc
gggcgggtcgaactgcgcaccggcgacgccgccgacgtcaccggcctgccggccgggttc
ttcgacacgatcgtgctcaactccgtcgtccagtacttcccgagcgggacgtacctcctg
gatgtggtgcgcaaggccctggaactcctggcgccgggcggctcgctcttcgtcggagac
gtccgcgacctgcgccaggtccgggcgttccacacagctgtggcccaggcgcgcggcggt
gacgtcgaacagcggctgctgcgggagaaggagctgctcgtcgcgccggagttcttcgcg
ggcctcgacggagtcgcggcggacatccgggtcaagcgcggccgggcggtcaacgaactc
acccagtaccgctacgacgtcgtcctgcgccccggtgccgccgggccgctcccaggggca
acgctgacctggggtaccgatgtgtccactgtggacgaggtggcggaacgggtccgcgac
ggcctgcgcgtcgagggcgttcccaacgggcggatcaccgaaggcgtgaaccccgaggac
tggtacgaactcggcgcggtcgtgacctggtccgcggccgctgacggctcggtcgacgtc
ctgttcaccagcggcgacccggccggcgcgttccggcccggcccggagccgctgctctcc
tacaccggcaatccccggcggtcgcaccggagcaccgccctgcccgcggacctgcgcgcg
ctggccgccgaacggctgcccgagcacatggtgccgtcggcgatcgtcgtgctcgacgcg
cttccggtgacggcgaacggcaagctcgaccgccgcacgctcccggccccggagaggagc
gcgcccgtctccggccgcgagccgcggacgccggtcgaacggcagctgtgcgagctgttc
gccgacgtcctcggcctcccgcgggtgggcccggacgacagcttcttcgcgctcggcggg
cattcgctgctggccacccggctgatcgcccgcgtccgcgcggccctgcacgccgagctc
gaagtgcgggcggtcttcgagacgccgaccccggccggcctggccggggtgctcgccacc
gcccgcggcgccgcgcggccgccgctggtccccgcgcctcgcccggagctcgtcccgctg
tccggcgcccagcagcggctgtggttcctgcaccacctcgaaggggcgtcggccacctac
aacgtcccgctgatcatgcggctggaaggcgatctcgacgtcgaagcgctgcgcagggcg
ttgtccgatgtggtcgcccgccacgaggcactgcggacccggttcccacagcgggacggt
gtgccctaccaggacatcctcgcgcccggggaggtcgaccttcccgtccgcgaggtcgcc
gaactcgacgagaccctgaccgggctggtccgcggatcgttcgatctcgagcggcacgtg
ccggtgcgcgcggagctgctgcggctcggcgcccgcgagcacgttttcgccctcgtgttc
caccacatcgcctccgacggctggtcgatggccccgctgtggcgcgacctcgccacggcc
tacgccgcccgaggcgccggcgaagctccacagtggacgccgctgccggtgcagtacgcg
gactacacgctgtggcaccgggatctgctcggccgcgaagacgacccggacagcgtcctg
agcgcgcagctggactactggcggacggccctcgacggcctgccggaccggatcgagctg
cccctggaccggccgcacccggcgaccgcgaccttccgcggcgagctgcacaccttcacc
tgggacgccggcctccacaccgggctggccgaactggcccgcgagagcggcgccagcgtg
ttcatggtcgtgcacgcggccctcgccgccctgctcacgcggctgggcgccggcacggac
gtgccgatcggctcgcccatcgccggccgcaccgacccggccttggacgacctcgtcggc
ttcttcgtcaacaccctggtcctgcgcgtcgacaccggcggcgagccgacgttccgcgaa
ctgctcgcccgggtccgcgaacgcaacctcgacgcgtacgcccaccaggacgtgcccttc
gagcgcctggtcgaactgctcaaccccgcgcggtcaccgtcctaccacccgctgttccag
gtcatgatcgccgggcagaacaacgcccgggccgaggtgaccctgcccggcctggccgtc
accgagctcccggtgaccacggggacgtcgaagttcgacctctcgatttcgctgaccgag
cgcgacgccgggatcgccggggtgctggagttcaacgccgacgtcttcgaccacgcgggc
gcgaacgcgatcctgcgccgcctcgaagtcctgctgcgcgcggccctggccgagcccgac
cgcccggtcggcgccctcgacctcctcgacggggacgagcgcgaccgggtgctcaccgaa
tgggcggggtcgctcgaaccggcgggcaccgagacgttccccgggatgttcgcccgccgc
gtcgccgaggcaccggatgcggtggcgctcgtgttcgaggacgtcgagctgacctacgcc
gaggtgaacgcccgcgccaaccggctcgcgcacttgctgctcgagcgcggtgccgggccg
gagcgggtggtcgcgctggccgtgccgcgctcggtggacatgatcatcgccgagctggcg
gtgctcaaagccggtgccgcgtacctgccgatcgacgtcgactacccgggcgaccgcatc
gcctacatggtcgaggacgcggccccggtctgcgtggtgacgacccgggacatcgaggcg
aagctacccacaaccctgcctcgggtccttctggacgacgcggcactcaccgcgatgtcc
acagaggacccttcggtggtggtccggccggagaacgcggcctacgtgatctacacgtcg
ggctcctccggacggcccaagggcgtcgtcctccagcactcgggtgtcgcgaagctggtc
gccacccaggtcgaacgcttcggcgtcggcccgcacagccgggtgctgcagttcgcgtcg
ccgagcttcgacgtcgcgttctgggacctctgcctcggcctgctctcgggcgggcggctg
gtcgtcgtcccggccgagcggcgggtcgcgggcccggcgctgaccgagtacgcgcacgcc
cacggcgtcgacttcatgatcctgccacccgcgctgctcgacgccatgccggcggactgt
gacctcccgcgggacggtgtgctgctggcggggaccgagcgcgtgtcgccggagctggtg
cgccgctgggcgccgaggcggcggatgttcaacgcctacggcccgaccgaggcgaccacc
aactcgacgctcggggaaagcgacccggccgagctggcggacgcgaccgtcgtccccatc
ggcatccccgaccccggcacccgcgcgtacgtgctcgacgcccggctgcggccggtcccg
cccggtgtggtgggggagctgtacctcgcgggaagcggcctggcgcggggatatctcggg
cggccggggctgacggcggagcggttcgtcgcggaccccttcggttcgggcgggcggctc
taccgcacgggtgacctggtcaaatggcgtccggacgggcggctggtgttcctcggccgg
gccgacgaccaggtcaagatccgcggctaccgcatcgagctcggcgagatcgagtccgtg
ctggccgagcacccggccgtcgggcagtcagtcgtcgtcgcccgggacagccggctcatc
gcctacgccgtgccgtcggccggacgggacgaagaagcggaacgggaccacgtcggcgag
tggcgggagctgcacgagaacgtcttcaccgaagcggcgtccggcgggctggaggagaac
ttcaccggctggaactccagctacgacggctcggagctgcccctcgccgagatgcgggag
tggcacgcggcgacgatcgagcggatccgggcgctgcggccgaagcgggtgctggagatc
ggcgtcggcagcggtctgatcctgtcgcggatcgcgccggacgccgaggagtaccggggc
gtcgacctgtccgagcaggccatcgcgaacctgcggcgggaactcgcggcgacgccgttc
gcgagcaaggtccacctggccgcgcggcccgcccacgacctgggcgaactgccggacttc
gacacggtgatcgtcaactcggtcgcgcagtacttcccgagcgtcggctacctcgccgaa
gtcctccgcacggccgccgcgcacgtccggccgggtggtgtgctgttcctcggcgacatc
cggaacctccgttcgctgcgggcgttccggaccgcgaccgagctgcggcacggccgccgg
gacgtcgccgcggtggaccaggcgatcgctcgcgagggcgagctggtcctggaccctgac
ttcttcgcggccctggctctcgacggcttcgacgacgtcgacctgtgggtcaagcgcggc
cacgcgcacaacgagctgacccggcaccgctacgacgtcgtcctgcgaaaggcaccgcgg
cccgaagcggccgaagagcaggtcgtcgcgttcgcctcggtggacgagctggagcgggtc
ctggcggctcgcccggcccggctgcgcgtcaccggcgtgccggacgcccggttgtccggc
gaactcgccgccgtcgcggcgctggccgcgggcgacgccgagacggcactgtcctctctg
gaggatcggtccggagtggaccccgagacgctgcacgatctcggcggccgtcacggttac
cgcgcgtacgcgaccctcaccgcggacgtcggcgagctggaggtcgtgttcaccacgggc
gagcccacccggatccaccgcggccgcccggtccgggccgccctcgacgcgctgggcaac
cacccggccgggcagcgggacgcgagcgcgctggtggcggcgctgcgggcgcacgtccgc
gaccggctgccgcagtacatggtgccgtcggcgttcgtgctgctggaccggctcccgctg
ctggcttccggcaagctggaccggcgcgccctgccgaaccccgacaagcaggggacgtcc
acgggccgggcgccgcggacgccggtcgaagaagtcctttgcgggctcttcgccgaggtg
ctcgacgcggcgtcgatcggcgtcgacgacgacttcttcgccctcggcgggcattcgctg
atggcgacccggctggtcgcgcggctgcgcgcggtgttcggcgtcgaactgcaggtgcgg
tcggtgttcgagacgccgacggtggccgggctggccgccctgctgtccacttcggactcc
ggagcggcccggccggcgctggtgcgcgtcgatccgcgtccggacgtgctgccgctgtcg
ttcgcccagcagcggctgtggttcctgcaccgcctggaaggcccgtcggcgacgtacaac
atgccgacggcggtccggctgaccggcaccctcgacgtcgacgcgctgcgcacggcgctg
tccgacgtggtcgagcgccacgaagccctgcgcacggtcttccccgagatcgacggcgag
gcccggcagctcgtcctcggcgacgtcaccatcccgctgccgatccgcgcggtcaccgag
gccacgctcgccgacgcggtgtccgaagcggccgcgacggtgttcgagctcgaggcggag
atcccgctgcgggcgcagctgctccggctgggcgcccgcgaacacgtcctggtgctggtg
ttccaccacatcgcctccgacgggtggtcgaccgcgccgctgtggcgtgacctcgcgacg
gcctacaccgcccgccaggccggtgatgctccacagtggacggcgttgccggtgcagtac
gcggactacacgctgtggcagcgcgacgtcctcggcgagccggtgatcgagccccagctg
gcctactggcgcgaagccctcgccggcctgccggagcggatcgagctgcccaccgaccgg
ccgcacccggcggaagcgtcctaccgcggcgagcagttcgccttcggctgggacgcggaa
ctccacagtggactcgtcgagctggcccgcacctgcggcgcgagcgtgttcatggtcgtg
cacgccgggctcaccgcggtgctcacccggctcggtgcgggcaccgacatcccgctcggc
acgtccatcgccggtcgcaccgacgccgcgctcgacgacctcgtcgggttcttcgtcaac
accctggtcctgcgcgtggacaccggcggcgacccgtcgttccgcgagctcgtcgcccgg
gtccgggaccgcagcctcgacgcctacgcccaccaggacgtcccgttcgagcgcctggtc
gaagccctgaacccggtccggtcgctcgcctaccacccgctgttccagaccatgctggcc
tggcagaacaacgccgtcgccgacctcgcgctgccgggcctcaccgtcgcggaggagccc
gtccgcaccggcaccgcccgcgccgacctcacgttcttcgtcggcgagcggcccgggcac
cgggccgggatccgcggcaccgccgagtacaacaccgacgtcttcgaccgcgcgagtgtc
gaggcgatcctggagcggctgcggacgctcctggccgccgtcgtcgccgacccggacacg
cggatcggcgccgtcgacctgctcaccggcgtcgagcgcgaccagctcgccgccgacccc
gcgatccccctgcccgcggagacgcccgccgggctgttcgccgcccaggtcacccggaca
ccggacgctctggcgttggtgttcggctccgagcggctcacctacgccgaactggagacg
cgggccacggtcctcgcccgggcgctgctcgcgcggggagcgggcccggagcgcgtggtc
gcggtcgcgctgccgcggtcggtcgagctggtcgtcgcgctgctggcggtgctcaagatc
ggcgccgcctacctgcccctggacctgaaccacccggccgagcgcctcgagctgatgctc
gccgacgcggcaccgcacctggtcatcgcggaggacggcttcggggaccggctcgtccgg
ccgggggagaccgggccggaaccggcctggccgccgatcagcccggaccacccggcgtac
gtgatcttcacgtcgggctccaccggacgcccgaaggccgttgcgggaacccagcgagcc
ctggccaaccggctgcactggggccgctcggcgctcgggcccggcgtgcgcgtggccaag
agcgcgctgacgttcatcgacggctcgaccgagctgctcggcggcctggtcgcgggcgac
ccggtggtcctcgccgacgacgcgacggccaccgacccgatggccctggccgaattcgtc
cgcgagtccggcgctcaggtgctcaccgtggtcccgagcctcctcgacagcttcgccgaa
gacgcgtcggccggggcgttcgacgcggtgaccacctggatcaccagtggcgagccgctt
tcggacgttctcgccgagaaggtggcccggcggtggccgtcggcgaaactggtcaacctc
tacggctgttcggaagtcgcgggcgacagcctggcccaggtctgcgggccggtagcgatc
gggcggccgatcgcgaacacccgaacgtacgtcctcgatgccgcgttgcggccggtgcca
ccgggcgtacgcggcgagctgtacctcgccggtgccggactcgcgcgaggctacctcggc
cggccggcgctcaccgccgaacggttcgtcgcctcgccgttcgagccgggggagcggatg
taccgcaccggcgacctcgtccgccgccggcccgacgggacacttcagttcctcggccgc
tccgaccagcagatcaagatccgcgggttccgcgtcgagccgggtgaggtggaagccgcg
ctgagggccggcgcctcggtggcgcgcgcggtcgtgatcgcccgggagaaccggctgatc
gcctacgtggcgccgtcgggtgacccggtcgcgctgcgggcgtcgctcgccgcgcggctg
ccggagtacctggtgccgtcggcgatcgtcgtcctgcccgagctgccggtgaacgccaac
ggcaagctcgaccgcgccgccctgcccgacccgcaggtccgcgcgtccggccgggccgcg
cggaccccggccgagcaggcgttgtgcgagctgttcgccgacgtcctcggcgttgcggcg
gtcggcccggacgacgggttcttcgccctcggtgggcattccctcctggcgacgcggctg
gtcagccggatccgcgcgttgctcggcgtcgaggtgccgatccgggcggtgttcgacgcg
ccgaccccgggccggctcgccgaagccctggatccgggccggggccgccgtccggcgctg
gtccccgccccgcggccggacgtcctgccgctgtcgttcgcgcagcagcggctgtggttc
ctcgaccgcctggacgggctgtccgcgacctacaacatcccctgggcctgggagttgacc
ggcccggtcgacaccgacgcgctgcgagccgccttgggtgacgtcgtggcgcggcacgag
gtcctccggacgctcctggtcgaggagcagggcacgccccgccaggtcatcctcgatcgg
gccgaccccgtgctggtcaccgagacggctgccgacctcgacgagcgcgtcaccgccgcg
gcgtcgtactgcttcaccctcgacgccgaaatcccgatccgggccacgctcgtctcggcc
gggccggagcggcacgtgttcgtgctgctggtgcaccacatcgcgggcgacggctggtcg
ctgccgccgctgaagcgggacctcgacaccgcgtacgccgcgcggctcggcggtgaacgt
ccacaatggacgccattgccggtgcagtacgcggactacacgctttggcagcggcaaatg
ttcggccgcgccgacgatccggacagcctcctcggccgtcaggcggcgttctggcgtgac
accctcgcgggcctccccgacgagctggccctccccgccgaccggccgcgcccggcacgc
tcgaccggccgcggcgccgccgtgccgttcaccgtgcccgcttccgtccacaacggactc
cgggagctggcccaccgcagcgacaccagcacgttcatggtcgtgcaggcggtgctggcc
gccctgctgacccggctcggcgcgggcacggacatccccctggggacgccggtggccggc
cgcccggatcacgccctcgaagacctcgccgggttcttcgtcaacaccctcgtcctgcgg
accgacaccggcggcgacccgacgttccggcagctcctcgaccgcgtccgcgaggccgac
ctggccgcgtacgcccaccaggacctgccgttcgagcacctcgtcgagctgctcaacccg
ccccgatccttggcgcggcacccgctgttccaggtcatgctcgcggtctaccactcgggc
tcggagccggatcggttgctcgggctcgacgcggcctaccgggacaccgggctgcggcag
gcgaagttcgacctgtcgttcgacctcgtcgaaacggccgacggcatcgacggcgacctc
gaatacagcctcgacctgttcgacgagccgacggcccggacgctcaccgagcgcctggtc
cgggtgatggcggcggtcgtcgcggacccggaccggccgctgagccggatcgacgtcctc
gaccccggtgagcgggaacggatcctgcgcgactggggtgccggggcgccgctgaccctc
ccggcgccgacggtcctggatcggctggccggccaggtcgcggccaccccggacgcgacc
gcgctgagcgacgcgtcctcgagcgtcaccttcgcggagttcgccgcgcggaccgaccgc
ctcgcccggtggctggcgtcccagggggctggaccggagaaggtcgtggcgctggtcctg
ccgcggtcggcggcggtcgtcgaggcgatcttcggcgtgttcaagacgggcgcggcctac
ctgccggtggatccggaccagcccctggaacggatctcggcgatcctcgccgacgccgat
cccgcgctggtgctcacgagccgttcgctggcttcggtcgttcctggcgccttgctcgtc
gaggacattgtggacagtgacgcgacactgatcccgccttcgcccgcgaacccggcgtac
gtgctctacacctcgggctcgacgggcaagcccaagggtgtggtcatcccgcactccggg
ctcgtcaacctgttccacagccaccgcgagacgctgtaccgaccggccgtcgccgcggcg
ggcgggcggcggctgcgggtcgggcacgcgtgggcgttcttcttcgacgcgtcctggcag
ccgcagctgtggctgctcgacgggcacgaggtgcacgtcgtcgacgacgacacccgccgc
gacccggaccggctggcggcggtggtgcgcgaacgcgggctcgacttcctcgaactcacg
ccgtcgcacttcgcgcagctggccgcggccggggtgatctcggccggccggtgcgccctc
ggcgtggtcggcgtcggcggtgaagccgtgtcgcagaccctgtgggagacgctgtcgtcg
atgccgggcacccaggcgtacaacctctacggccccaccgaggccacggtggacgcgctg
gtcggccggttcggcgacgccgaccggccggtgatcgggcgcccggtgcacaacacgcgg
gcgtacgtcctcgacggcgggctttcgccggtcccggcgggcgtgccgggcgagctgtac
ctggccggcgccgggctggcccgcggctaccacgggcggccgggcctcaccgcggaccgg
ttcgtcgcctcgccgttcgagccgggcgagcggatgtaccgcaccggcgacctcgtgcgg
tggcggccggacgggcagctggaatacctcggccgcaccgacgaccaggtcaagatccgc
ggcttccggatcgaacccggcgaaatcgagacggcactggcccgccacgacgacgtcacg
caggccctggtcgtcgtccgcgaagaccgggacaagcggctggtcgcctacgtcaccccg
gcgaccgcggatcccgcgcggttgcgggagttcgccgcccggtcgctgccggagtacatg
gtgcccgcggcgatcgtcccggtggacgcgtttcccgtgacacccaacgggaagctggac
aaggcggcgctcccggtgcccgacgtcgcggctcgcggccgggcgccggagacgccgctc
gagcaagccctctgcgagatcttcgcggaggtgctggacgtcgccgcggtcggcgccgac
gacgacctgttcaccctcggcggccactcgatgctgctggtggtcctgcgcaaccggatc
accgagcggctcgggaccgaattgcccatcgccgagttcttccgtacccccaccgcggcc
gggctggccgcgctgtcgacccgaaacccggagtag
DBGET
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