Amycolatopsis mediterranei U32: AMED_6255
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Entry
AMED_6255 CDS
T01269
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
amd
Amycolatopsis mediterranei U32
Pathway
amd00300
Lysine biosynthesis
amd00550
Peptidoglycan biosynthesis
amd01100
Metabolic pathways
amd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
amd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AMED_6255 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AMED_6255 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AMED_6255 (murF)
Enzymes [BR:
amd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AMED_6255 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADJ47990
UniProt:
A0A0H3DAF0
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Position
complement(6928831..6930333)
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AA seq
500 aa
AA seq
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MIVLSLAEIADVVGGRLHRADPGAQVTGTVEFDTRELTSGGLFVALPGEKVDGHDFAAQA
VEAGAVAVLAAREVDAPAIVVPPLAAGEAHERSVALTGDKDGSGAAVLAALAKLARYVVQ
RLAEGELTVVGVTGSSGKTSTKDVIAQLLEPLGPTIAPPGSFNNELGHPWTALRAGAETR
HLVLELSARGPGHIAHLAAIAPPKIGVVLNVGSAHVGEFGSREGIAKTKGELVEALPEDG
VAVLNLDDPLVAAMASRTKARVVFVGESPSAQVRAENITLDDEARASFRLITPAGEAGVK
LPLHGEHHVGNALSAAAVALELGATPEEIATRLSALERRSARRMEVVTRPDGVTILNDSF
NANPESMRAGLKALAAMTRETGRRSWAVLGVMGELGADSVTAHDEIGRLVVRLNIAKLVV
IGPEAAAMHQGAHQEGSWGEESTLVPDVEAAAALLHDQLRPGDVVLVKASKAAGLWRVAE
ALLEPRETDNSENRSNGGDA
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgtgctcagcctggccgagatcgccgacgtcgtcggcggccggctgcaccgcgcc
gacccgggcgcgcaggtgaccggcaccgtggagttcgacacccgggagctcacgtccggc
ggcctgttcgtcgcgctgccgggggagaaggtcgacggccacgacttcgccgcgcaggcc
gtcgaggccggcgccgtggccgtgctggccgcccgcgaggtcgacgcgcccgcgatcgtc
gtcccgccgctcgccgcgggcgaggcccacgagcggtcggtcgcgctgaccggcgacaag
gacggctccggtgccgcggtgctggccgcgctggccaagctcgcccggtacgtcgtgcag
cgcctggccgagggcgagctgaccgtcgtcggcgtcaccggctcctccggcaagacctcg
accaaggacgtcatcgcgcagctgctcgagccgctcggcccgacgatcgcgccgcccggg
tcgttcaacaacgagctcggccacccctggacggcgctgcgggccggcgcggagaccagg
cacctcgtgctggagctgtcggcgcggggtccggggcacatcgcccacctcgcggcgatc
gccccgccgaagatcggcgtcgtgctcaacgtcggcagcgcgcacgtcggcgagttcggc
tcgcgcgaaggcatcgcgaagaccaagggcgagctcgtcgaggcactgcccgaagacggc
gtcgcggtgctcaacctcgacgacccgctggtcgcggccatggcgagccgcacgaaggcc
cgggtggtgttcgtcggcgagagcccctcggcgcaggtccgcgcggagaacatcaccctc
gacgacgaggcccgggcgtccttccggctgatcaccccggccggcgaggccggcgtcaag
ctgccgctgcacggcgagcaccacgtcggcaacgcgctgtccgccgcggcggtcgcgctg
gagctgggggcgacgccggaggagatcgccacgaggctctcggccctcgaacggcgctcg
gcgcgccgcatggaggtcgtcacccggcccgacggcgtcacgatcctcaacgactcgttc
aacgccaaccccgagtcgatgcgggccggcctgaaggccctcgcggcgatgacccgggag
accggccgccgctcctgggccgtgctcggcgtgatgggcgagctcggcgcggactcggtc
accgcccacgacgagatcggccggctcgtcgtccggctcaacatcgccaagctcgtcgtc
atcgggcccgaggcggcggccatgcaccagggcgcgcaccaggaaggctcctggggcgag
gaatccactttggtacccgacgtcgaggccgccgccgccctgctgcatgatcagctccgc
cccggggacgtggtgctggtcaaggcctccaaggccgccggcctctggcgggtcgccgaa
gctctgctcgaaccccgggaaaccgacaactccgagaatcgctcgaacggtggtgacgcg
tga
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