KEGG   Amycolatopsis mediterranei U32: AMED_7571
Entry
AMED_7571         CDS       T01269                                 
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase E1 component subunit alpha
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
amd  Amycolatopsis mediterranei U32
Pathway
amd00280  Valine, leucine and isoleucine degradation
amd00640  Propanoate metabolism
amd00785  Lipoic acid metabolism
amd01100  Metabolic pathways
amd01110  Biosynthesis of secondary metabolites
amd01210  2-Oxocarboxylic acid metabolism
Module
amd_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:amd00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    AMED_7571 (pdhA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    AMED_7571 (pdhA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    AMED_7571 (pdhA)
Enzymes [BR:amd01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     AMED_7571 (pdhA)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N HTH_71 Transketolase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: ADJ49284
UniProt: A0A0H3DHZ9
LinkDB
Position
complement(8362870..8363955)
AA seq 361 aa
MAVMSSETLLPSATPVRFVAEDGSRADEHGGYGEPTGDRLKEAYRLMVLGRRFDVQATAL
TKQGRLAVYPSSAGQEACQVAAALTLETRDWLFPTYRDSVALVARGLKPGEVLTLLRGDA
HCGYNPVETRVAPQCTPLATQTLHAAGLAHAMQRRGEDAVALALIGDGATSEGDFHEALN
FAAVFKAPVVFFVQNNRFAISVPFEKQSAAAALAYKGVGYGMRSEQVDGNDAVAVLAVLD
DAVKHAREGKGPVLVEAHTYRIDAHTNADDATRYRDAEEVAKWREADPLKRLETFLKSRN
LLQDTEIERFAAAAEVFAQSVRDTLNTEPELDPLSLFDHVYAEPTPQLRRQRAALEAELE
A
NT seq 1086 nt   +upstreamnt  +downstreamnt
atggctgtgatgtcttcggagaccctgctgccgtccgctaccccggtgcggttcgtcgcc
gaagacgggagccgggccgatgagcacggtgggtacggcgagcccaccggagaccggctc
aaggaggcctaccggctgatggtcctgggccgccggttcgacgtgcaggcgaccgcgctc
accaagcagggcaggctcgccgtctacccctccagcgccggccaggaggcctgccaggtc
gccgcggcgctcaccctcgaaacccgggactggctcttcccgacctaccgcgactccgtc
gccctcgtcgcccgcggcctgaagcccggcgaagtcctgacgctgcttcgcggcgacgcg
cactgcggctacaacccggtcgagacgcgcgtagcgcctcagtgcactccgctggcgacg
cagactctgcacgccgccgggctggcgcacgcgatgcagcgacgcggcgaagacgctgtc
gcgctcgcgctcattggggacggcgccaccagcgaaggcgacttccacgaagcgctcaac
ttcgcggccgtcttcaaggcgcccgtcgtgttcttcgtgcagaacaaccgcttcgccatc
tcggtgcccttcgagaagcagagcgccgcggccgcgctggcgtacaagggcgtcggctac
ggcatgcgctcggagcaggtcgacggcaacgacgccgtcgccgtcctggccgttctcgac
gacgcggtgaagcacgcgcgcgaaggcaagggaccggtcctcgtcgaggcccacacctac
cgcatcgacgcccacaccaacgccgacgacgccacccgttaccgcgacgccgaagaagtc
gcgaagtggcgcgaagcggacccgctcaagcggctcgagaccttcctcaagagccggaac
ctgctgcaggacaccgaaatcgagcggttcgcggccgccgccgaggtgttcgcccagtcc
gtccgcgacacgctcaacaccgagcccgagctcgacccgctgtcgctgttcgaccacgtc
tacgccgaacccaccccccagctgcggcggcagcgggcggccctcgaagccgaactggag
gcctga

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