Amycolatopsis mediterranei U32: AMED_9047
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Entry
AMED_9047 CDS
T01269
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
amd
Amycolatopsis mediterranei U32
Pathway
amd00230
Purine metabolism
amd01100
Metabolic pathways
amd01110
Biosynthesis of secondary metabolites
Module
amd_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
amd00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
AMED_9047 (purL)
Enzymes [BR:
amd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
AMED_9047 (purL)
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ADJ50736
UniProt:
A0A0H3DJ64
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Position
complement(9894556..9896838)
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AA seq
760 aa
AA seq
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MTSTVDTTERAGATPDHTQPYRELGLADDEYARIREILGRRPTDAELAMYSVMWSEHCSY
KSSKKHLRYFGDTATDEMKAKMLAGIGENAGVVDIGEGWAVTFKVESHNHPSYVEPYQGA
ATGVGGIVRDIMAMGARPLAVADALRFGPADAPDTKRVLPGVVAGVGGYGNCLGLPNIGG
ELVFDPSYSGNPLVNALCVGAMRVEDLHLAFASGTGNKIILFGARTGLDGIGGVSVLASD
TFSGDESSGGRKKLPSVQVGDPFTEKVLIECCLELFAQKLVVGIQDLGGAGLSCATSELA
AAGDGGMHIYLDRVPLRATGMTPAEVLSSESQERMCAVVSPENVEAFMAVCRKWDVIATD
IGEVTDGEHLVITWHEEVVVDVPAHTVAHQGPVYDRPIERPSFQDALIADTSASLPRPST
PDELRADVLRLISSPNQASKEWVTSQYDRYVRGNSVLAQPSDSGMIRIDESTGRGVSVAT
DCNSKFVYLDPYRGAQLALAEAYRNVATGGATPVAVSDCLNFGAPTDPGVMWQFEQAVHG
LADGCVELGIPVTGGNVSFFNQTGSTAILPTPVIGVLGVIDDVTRRIPTGIGAEAGETLL
LLGETHDELDGSAWARELHGHLGGVPPRVDLAREKLLGEILVAGSRDGMISAAHDLSDGG
LIQTLVETVLIGQCGVRVFLDADQDPFVQLFSESAGRVLVAVPRTEELRFTEMCTARGLP
WRKTGVVDPESGTLELQDITEFTLDELREAWERTLPALFD
NT seq
2283 nt
NT seq
+upstream
nt +downstream
nt
gtgaccagcaccgttgacaccaccgagcgtgccggggcgaccccggaccacacccagccc
taccgcgagctcgggctcgccgacgacgagtacgcccgcatccgggagatcctcggccgc
cggcccaccgacgcggagctggcgatgtactcggtcatgtggagcgagcactgctcgtac
aagtcgtcgaagaagcacctgcggtacttcggggacaccgccaccgacgagatgaaggcc
aagatgctggccggcatcggcgagaacgcgggggtcgtcgacatcggcgagggctgggcc
gtcaccttcaaggtggagagccacaaccacccgtcctatgtggagccttaccagggcgcg
gcgaccggcgtcggcggcatcgtccgcgacatcatggcgatgggcgcgcggcccctcgcg
gtcgccgacgcgctgcgcttcgggccggccgacgcccccgacaccaagcgcgtgctgccc
ggcgtggtcgccggcgtcggcggctacggcaactgcctcggcctgccgaacatcggcggc
gagctggtcttcgacccgtcctactcgggcaacccgctggtgaacgcgctgtgcgtcggc
gcgatgcgcgtcgaggacctgcacctggcgttcgcctccggcaccggcaacaagatcatc
ctgttcggcgcgcgcaccggtctcgacggcatcggcggcgtttccgtcctggcgagtgac
accttttcgggtgacgagtcctcgggtggccgcaagaagctgccgagcgtccaggtcggc
gacccgttcaccgaaaaggtgctcatcgagtgctgcctcgagctgttcgcgcagaagctc
gtcgtcggcatccaggacctcggcggcgccgggctgtcctgcgcgacgtcggagctggcc
gcggccggcgacggcggcatgcacatctacctcgaccgggttccgttgcgcgccaccggg
atgacgccggcggaggtgctctccagcgagtcgcaggagcgcatgtgcgcggtcgtctcg
ccggagaacgtcgaggcgttcatggccgtctgccgcaagtgggacgtcatcgcgaccgac
atcggcgaggtcaccgacggcgagcacctggtcatcacctggcacgaggaggtcgtcgtc
gacgttcccgcgcacacggtggcccaccagggcccggtgtacgaccggccgatcgagcgt
ccgtcctttcaggacgctttgatcgcggacacgtcggcctcgctcccgcgtccgtccact
ccggacgaactgcgcgcggacgtgctccggttgatttcgtcgccgaaccaggcgtccaag
gaatgggtgacgtcgcagtacgaccggtacgtgcgcggcaattccgtgctggcgcagccg
tcggactcgggcatgatccggatcgacgagtcgaccggccgcggtgtttcggtggcgacg
gactgcaacagcaagttcgtctacctcgacccgtaccgcggcgcgcagctggcgctggcc
gaggcgtaccgcaacgtggccacgggcggcgcgacgccggtcgcggtgtcggactgcctg
aacttcggcgccccgaccgacccgggcgtgatgtggcagttcgagcaggcggtgcacggc
ctggcggacggctgcgtcgagctgggcatcccggtgacgggcggcaacgtgagcttcttc
aaccagacgggctcgacggcaatcctcccgacgccggtgatcggcgtcctcggcgtgatc
gacgacgtgacccgccgcatcccgacgggcatcggcgcggaggcgggcgaaacgctcctg
ctgctgggcgagacgcacgacgagctggacggctcggcgtgggcccgcgagctgcacggc
cacctcggcggcgtgcccccgcgtgtggacctggcccgcgagaagctgctgggcgagatc
ctggtggcgggttcccgcgacggcatgatctcggccgcccacgacctgtcggacggcggc
ctgatccagacgctggtcgagaccgtcctcatcggacagtgcggcgtccgcgtgttcctc
gacgcggaccaggacccgttcgtgcagctgttctcggagtcggcgggccgagtgctggtg
gcggtcccgcgaacggaagaactccgcttcacggagatgtgcacggcgcgcggcctcccg
tggcgcaagaccggcgtggtcgacccggagtcgggaacgctggagctgcaggacatcacg
gagttcacgctcgacgagctgcgcgaggcctgggagcgcacgctcccggccctgttcgac
tga
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