KEGG   Apis mellifera (honey bee): 408804
Entry
408804            CDS       T01057                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
ame  Apis mellifera (honey bee)
Pathway
ame00562  Inositol phosphate metabolism
ame01100  Metabolic pathways
ame04070  Phosphatidylinositol signaling system
Module
ame_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ame00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    408804
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    408804
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ame04131]
    408804
Enzymes [BR:ame01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     408804
Membrane trafficking [BR:ame04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    408804
 Endocytosis
  Macropinocytosis
   Phospholipase C
    408804
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RA C2 EF-hand_like RasGEF EF-hand_PLCG2
Other DBs
NCBI-GeneID: 408804
NCBI-ProteinID: XP_016767298
BEEBASE: GB42984
UniProt: A0A7M7IJT7
LinkDB
Position
LG4:8940540..9048511
AA seq 1700 aa
MEIVAGLKSNKLKPFWNSVNEPVPVLESLSSALLSSEYEFALARSLAMPECPVVPFFGAF
LRELREVIAFESKSQYAECKDNRESPRRSSKDVESENVSSSGQTTKIAIDTGTESSTEWN
TRNSSLRKIENTPIRDTGSVLEKIGEFHKHQHARGRDATTGSLHRTLSIHTTAIEQTYMA
EECDENDYHFDLDSYKPVQPITIDHGVALFPVAAPHTGMDLHLLQVLHHGTTLVHWDCEG
GATRTALVFARVDRACGTFVWEKPPWSPLKTAQLGGTASSTEFSLTANPEDTVPAGLLSK
YAAQQQADCASVTLEEGYLNLSSVKEVMIGCCDRDRETELRSICKRYGLSGSDSCIGLMY
GSSLPDNRLIFLLCPPALSKIWYMGLCWILRGLKRQQQLTDRRSRWLKEKYLQLYFEEGC
LEPMTADAIRAFGGRDWSMTESIGTLSPTSSSNLRKRNTKGKKTKSIGNIHALTKDLSLK
QFDSSSSDGGLSTAPLRHITGSRESLTRIIPASPRSSRDRVPPRSPPGSAERIISSNLPY
SSFQSLLCVARDKDKNGSGMSGGLEAPWQVKARTTSIMYETQLNFVEFVALFRSFSLRAR
KDLRDLFGQLAITCRSQSDGSLRDFNVRPPVLRQTSDATPQRIGLLTRNNSIDCREYKTS
SNLQKKQVFDAVAAASIVNNCSGVDTSKSQVITLATFTKFLESRQQEKLTDDEIKALVKR
HEPDPGLRTQWCLSFEGFARYMMDKDNYAFPNEYATPFETEMQQPLSQYYIASSHNTYLT
GHQLKGESSVQLYSQVLLTGCRCVELDCWDGDDGSPVIYHGHTFTTKIPFRSVVEAIDRS
AFVSSPYPVILSIENHCSQSQQARMAQIFQSVFGDKLVTKFLFETDFSDDPQLPSPSQLR
YRILIKNKKLVVDPAGPLAHPPLSHRGKMLMTDRASSMKQMRTDVSSASVVSEYFSEDDD
DEEDDDEDDNIDDNSISSYERYLGGTQVAHTRLKSDSAVDDKSQKQSSQIAKELSDLVIY
LQAIKFRGLNTTPGTAAAIGKTRHQPHTGPVQRHSIAGIGATSIGASSGSPQSLSTSASL
ASGGSNIENLFRFTRGVPACFQCSSLNESTAKKICRKQPLGVVAHAETQLIRTYPAGMRI
DSTNFNPVIFWAFGIQMVALNYQTDDAGLNLNAAMFEQNGQCGYVRKPSVMWDKGHMMYR
RFNPWDKEFDGLHSAHLTLSIVSGQYVSPTNFVASTYVEIELVGIPIDCAKHKTKVIQSN
ALNPIWNEKFCFQVMFKDLAFLRFGIVEASSHHLIAQRVIPLKCLKPGYRHVRLRSCKNK
PLALSTLFIYSRLEEESLDYNTCCRDHKESSKRPSSGKEPEKLTTVDPGLGGVTLKRRMF
FLMVYHVIPDEPYTILKVTQESTTQEVMLQALQKAGISADRVDEYILVEEVSCGWEKRDR
EELPTQRVLDPTEHPLQAQALWKGQGRFLLKRVGDDPSSRAWLASIRSTAGHSKLDSERD
TSTHIWDEADTFLVCIYNVSPDIPYAILRVPVSSSAQDVLAQALVKARRMEDPIKFALVE
ELEWGGTGAVGSGSRQLRVLRDDENVYSTQAFWKTLGRFIMREREQAIPRRHLLPATLDR
LSKGFSVGRSVSLPGSSKEKVPVSEALSDPTSRGLRHRLLMHGRRREVHSDGEDSRESDI
LNAALHLKKVSLRKLRVWKS
NT seq 5103 nt   +upstreamnt  +downstreamnt
atggaaatcgttgctggcctcaagtccaacaagctgaaacccttttggaacagcgtgaac
gagccggtaccagttttggaaagcctctcctccgcccttttgtcatccgagtatgaattc
gcgcttgcccgctcgttggctatgccggaatgcccggtggtcccattcttcggggctttc
ttgcgggaattgcgggaagtcatcgcattcgagtccaagtctcagtacgcagaatgcaag
gacaaccgcgaatcaccacgcagaagcagcaaggatgtcgagtccgaaaacgtgtcatcc
tcggggcaaaccacgaagatcgctatcgacactggcacggaatcatccacggaatggaac
acgaggaacagttctttgaggaaaatagagaacaccccgatccgtgacactggctctgtc
ctcgagaaaatcggcgaatttcataagcatcagcacgctcgaggcagggacgcgacaact
ggttcgctccatcgcactctgagcattcacacgactgcgattgagcagacttacatggcc
gaggaatgtgacgagaacgactatcatttcgatctcgactcctacaaaccggtgcagcca
atcacgatcgaccatggggtcgccttatttcccgtcgccgcaccccacacaggaatggat
ctgcatctattgcaggtgttgcatcacgggacgacgttggtgcactgggactgcgagggc
ggtgccacgaggacggcgttggttttcgcgcgagtggatcgtgcctgcggcaccttcgtc
tgggagaaaccgccgtggagcccgttgaagaccgcgcagttaggcggcacagcttcctcc
acggagttctccctaactgccaatccggaggacacggtgccggccggccttctgtccaag
tacgccgcccaacaacaggccgattgcgcctccgtcacgttggaggagggttacctgaac
ctgagctccgtgaaggaggtgatgatcggttgttgcgaccgggacagggagaccgagctg
agaagcatctgcaagaggtacggcctgtccggatccgactcgtgcatcggccttatgtac
ggctcaagcctgccggacaatcgactgatctttctcctttgcccccctgcgcttagcaaa
atttggtatatgggtctttgttggatattaagaggcctgaaacggcaacaacaattaacg
gatcgtaggtcgcgatggttgaaagagaaatatcttcagctttatttcgaggaaggttgc
ctcgagccaatgacagctgacgctataagggctttcggcggtcgcgattggtccatgact
gaaagtattggaacgctttcaccgacgagtagcagtaatcttcgtaaacgaaacaccaaa
gggaagaaaacgaaatctatcggcaatattcacgcgttaacaaaggatttgagcctaaag
caattcgactcctcgtcttcggatggaggcttatcaacggccccacttcggcatattacg
ggtagcagggaatccttgacgagaatcataccggcatccccacggtctagcagggatcga
gtgcccccacgcagccctcccggatcagccgaacgaattattagttccaacttgccttac
tccagctttcagagcctattgtgcgtcgccagagacaaggataagaatggatcgggaatg
tcgggtgggctggaggcaccttggcaggtgaaagcgcgcaccacttccataatgtacgaa
acgcagttgaactttgtcgagttcgtcgctttgttccgctcgttcagcctgagagcgaga
aaggatttgcgcgacttgttcggccaactggccatcacttgccgtagccagagcgacggc
tctttgagagacttcaatgtacgcccccccgtgttgaggcagaccagtgatgcgacccct
caacgaatcggtcttttaacgaggaataattccatagactgtcgtgagtacaaaaccagc
agcaaccttcaaaagaagcaagtttttgacgcggtggctgcagccagtatcgttaataat
tgttccggcgttgatacctcgaaatcccaagtaatcaccctggcgacattcactaaattt
ttggaatctcgtcaacaagagaaattgaccgacgatgagatcaaggcgctggtcaagcga
cacgagccggacccagggctacgtacacaatggtgtttgtctttcgagggctttgcacgg
tacatgatggacaaggacaattatgctttcccaaacgagtatgcaacgccgttcgagact
gaaatgcaacagccattgtcccagtattacatcgccagctcgcataatacttatttaaca
ggtcatcaactcaaaggagaatcctcggtccagctttactctcaggtactactaacagga
tgtagatgcgtagaactggattgctgggatggcgatgatggatcccctgttatttaccat
ggtcacactttcactacgaagataccgtttcgctcggtcgtagaagcgatcgacaggagt
gctttcgtcagttccccgtatcctgtcatcctctccatcgagaatcattgttcacaaagc
caacaagctcgaatggcccaaatatttcaatcggtatttggggacaaactggtgaccaag
ttcttgttcgagaccgatttcagcgacgacccccaactgccatcaccgtcgcagttgcgc
tatcgaatattaatcaagaacaaaaaactggtggtagatcctgccggccctttggcccat
cctcctttgagccatcgtggaaaaatgctgatgaccgatcgtgcgtcgtccatgaaacag
atgcgaaccgatgtgagcagcgcttccgtcgtttccgaatatttcagcgaagatgacgac
gacgaggaggatgacgacgaagacgacaatatcgatgataactccatttccagctacgaa
aggtatttgggcgggacgcaggtggcgcatacccggttaaaatcagattccgcggtcgac
gataagtcacagaaacaaagtagccaaatagccaaagaactttcggacttggtgatttat
ctgcaggctattaaatttcgtgggctgaatacgacaccggggaccgcggcggctatcggg
aaaacgcgtcatcaaccgcacaccgggcctgtacagaggcacagtatagctggaatagga
gccaccagcatcggtgcatcttccggttcaccacaatccctgtcaacatcggcttcgtta
gctagcggcggcagcaatattgaaaatctgttcagattcactcgtggagttccagcttgc
ttccaatgctcctccctgaatgaaagcacagcgaaaaagatatgcaggaaacagcctcta
ggggttgtcgctcatgcagaaacccaattgatacgaacgtatccagctggtatgcgtatc
gactcgacgaatttcaatcctgtaatcttctgggctttcggcattcaaatggtggcgcta
aattatcaaacggacgacgccgggctgaatctgaacgctgccatgttcgagcaaaacggg
cagtgcggatacgtcagaaaaccttcggttatgtgggacaagggtcacatgatgtacaga
cgattcaatccatgggacaaagaattcgacggtctacattcggcacatctgacgctctcg
atagtttcaggccagtacgtctctccgacgaatttcgtggccagcacttacgtggaaatc
gagctggtcggtataccgatcgattgcgccaagcataaaacgaaagtaatacagagcaac
gcgctcaatcctatctggaacgagaaattttgcttccaagtaatgttcaaagacctggcg
ttcctgcgattcggcatcgtggaagcgagctcccaccacttgatcgcccagagggtgatc
ccgttgaaatgcttgaagcccggctacaggcacgtgcggctacgctcctgcaagaacaaa
cctttggccctgtccacgctctttatctattcccgtttggaggaggagagcctcgattac
aacacgtgttgccgggatcacaaggagtcgtcgaagcggccctcgtccggcaaggagccg
gaaaaactgaccaccgtcgatcccggattgggcggggtcacgttgaagaggaggatgttc
ttcctgatggtttaccacgtgataccggacgagccttacaccatactgaaagtgacgcag
gagagcaccacgcaagaggtgatgctgcaagctctccagaaggctggaatatcggcggac
cgcgtcgacgagtacatcctcgtcgaggaggtgtcttgcggttgggagaagagggacagg
gaagagttgcccacccaacgggtcctggatccgaccgagcatccgttgcaagctcaagct
ctgtggaaggggcagggacggttcctgttgaagagggtgggcgacgatccgagcagcagg
gcatggttggcctcgatcagaagcacggccggccactcgaagctcgactccgagagggac
acctcgacgcatatctgggacgaggctgacacgtttctcgtttgcatctacaacgtgtcc
cccgacataccgtacgcgatactccgcgtccccgtcagcagctccgcccaggacgttctt
gcccaggcgttggtcaaggccagaaggatggaggatccgataaagttcgctttggtcgag
gagctggagtggggcgggacaggggctgttgggagcggtagccgccaactgagggtgttg
cgcgacgacgagaacgtgtacagcacccaggcgttttggaaaacccttggaagattcatc
atgagggagagggagcaagcgatacccaggcggcacctgttgccggccaccttggacagg
ctcagcaaaggcttctccgtggggaggtcggtctccttgcccggttccagcaaggagaag
gtccctgtctccgaagccctctccgacccgacctccagagggctcaggcatcgcctgctg
atgcacggccgtaggagggaagttcactcggacggcgaggatagccgcgagtccgatatc
ttgaacgcggccctccacttgaaaaaagtgtcgttgagaaagttgagggtgtggaagtca
tag

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