Aeromonas media: B224_0087
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Entry
B224_0087 CDS
T03075
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alan ineligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
amed
Aeromonas media
Pathway
amed00300
Lysine biosynthesis
amed00550
Peptidoglycan biosynthesis
amed01100
Metabolic pathways
amed01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
amed00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
B224_0087
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
B224_0087
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
B224_0087
Enzymes [BR:
amed01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
B224_0087
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AHX59345
LinkDB
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Position
64969..66324
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AA seq
451 aa
AA seq
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MMTLRLADLAQVLDARLIGGDHEITAVSTDTRTLGKGALFVALRGERFDAHDFCDQAVQA
GASVLLVERELPLAIPQLVVADTLKGLGRLGKLVRERINPKVLAITGSCGKTTVKEMATA
ILRQEGEVLATAGNFNNEVGVPLTLLRLEAQHQFAVMELGANHPGEIAWTTSLAQPDAAI
INNVAAAHLEGFGSLEGVFHAKSEIFEGLSEGGTAIVNADNEFWPKWQAKGIHCAFSLED
QSQPFHARDIVLNGQGCAEFVMVTPQGELTLTLAIPGRHNVANALAAAAGTLALGASLAS
VKAGLEQMAPVKGRFCVQRWGGLTLVDDTYNASVESVLAGIDALTAMSGYKVLVFGDMKE
LGEESAAQHARVGHHAREQSLDAVLTVGEQSRHTADAAAGRHFDNKASLFEVLAQMINTH
QEISILVKGARGSRMEDIVKMVVDRQESATC
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atgatgaccctcaggcttgccgacctggcgcaggtgctcgatgcccgtctgatcggtggc
gatcacgagatcacggcagtcagtaccgacacccgcactctgggcaagggggcgctgttc
gtcgcgctgcgtggcgagcgtttcgacgcccacgatttttgcgaccaggccgttcaggca
ggggcctctgtcctgctggtggagcgcgagctgccgctggccattccgcaactggtagtg
gccgataccctcaaggggctgggtcgcctcggcaagctggtacgcgagcggatcaacccg
aaagtgctggccatcactggcagttgtggcaagaccacggtgaaggagatggcgactgcc
atcctgcgccaggaaggggaggtgctggccaccgccggcaacttcaacaacgaggtgggg
gtgccgctcaccctgctgcgcctcgaggcgcagcaccagtttgctgtgatggagctgggt
gccaatcaccccggcgagatcgcctggaccacgtcgctggcccaacccgatgccgccatc
atcaacaacgtggccgccgcccatctggaggggttcggctccctggaaggggtgttccac
gccaagagcgaaatttttgagggcctgagcgagggtggcacagccatcgtcaatgctgac
aacgagttctggccgaagtggcaggcgaagggcattcattgcgccttctccctcgaggat
cagagccagccgttccacgcccgtgacatcgtactcaacgggcagggctgcgccgaattc
gtgatggtgacccctcagggggaattaaccctgaccctggccattccgggccgccacaac
gtggccaacgccctggctgccgctgccggtacgctggcgctgggcgcctcgctcgcctcg
gtcaaggccgggctggagcagatggcaccggtcaagggccgcttctgcgtgcaacgctgg
ggtggcctcaccctggtggatgacacctacaacgccagcgtggagtccgtgctggcgggc
atcgatgccctgaccgccatgagcggctacaaggtgctggtgtttggtgacatgaaggag
ttgggggaggagtccgcggcccagcacgcccgggttggacaccacgcccgcgaacagagc
ctcgacgccgtgctgacggtaggggaacagagtcgtcacaccgcagatgccgcggcgggt
cgacatttcgataacaaggcgtcgttgtttgaagtgcttgcgcaaatgataaatacacat
caagaaatctcgatcctggtcaagggtgcccgcgggtcccgcatggaagatatcgtcaag
atggtcgttgaccgtcaggagtcagccacatgctag
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