Anopheles merus: 121590819
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Entry
121590819 CDS
T08889
Name
(RefSeq) high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1
KO
K13761
high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:
3.1.4.35
]
Organism
amer
Anopheles merus
Pathway
amer00230
Purine metabolism
amer01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
amer00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
121590819
Enzymes [BR:
amer01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
121590819
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
HD
Motif
Other DBs
NCBI-GeneID:
121590819
NCBI-ProteinID:
XP_041766774
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Position
2R:9402723..9525313
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AA seq
1495 aa
AA seq
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MYHKDGTVDVKLLADLGYIADRLRNLEQKWDLTELKDLHRRIVLKLDDPPTSVLRLRETL
ARTPTVPPGSPDQQYQQEGQEELTNSTKEQEDAGLQLPVVIIADEVTPPSVIVEECAEAS
EVSPTADRGDDEFGESSNQSNSVQDVGNVEESVRKLDQLEELVIAFYHSCGRRSSRGCAD
TEQTASEAVRDGASRARAKRTKKRQQQSSGEACPGAYHPDQQHQKRHPDPDRTMNQGTDP
DQDRDHLAHAAAAAATSAPSDTSAVPVGDGRQQAQPQPLRSIHADAPEPGYCLDRDVPLD
DEEDTVTLTAETSSECCSQQTVVAVVAEEEEGEEAEAEEVVEDGSSPGHDPTETVAPGSD
TTTDDEVENDDTGGSDADANDEAEPGDTCTRRTVLGQDSTPSSRRCSLGGEFETEQNRRL
RRRLSELTNNFCTPKQFQQLCDNLDSITDNDLKLLVRELKRKIEFAERMNWLCLSSRPRG
PPHRKTSLPKHTDVKKRFLETCDKTLSDEVKAALRLPAFDSYEWEDWDVIHLMQTMFVEL
NLLEKFNIPIVTLREWLYEVYKHYNDVPFHNYRHCFCVAQMMYTIAWHTNLVQRLGELEV
LVLLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFR
NMSKEMYKDVREGIIRCILATDMARHNEILTQFQEATPEFDYSNKVHTNLLCMVLIKVAD
ISNEARPMDVAEPWVDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKPGSQVRFIGLVLL
PLFEALGELLPELTDLIITPVRVALDYYRRLNDAANKTRRSIAEAEAASSESGGSPQLPR
SQSGISVKSRRSIPSQKSASRTSVDEPILIAAELHDLPEGSESGDSETATEVDVAEKTSK
FKVDTESIHRKQSHPNSRKGSREKRPSMIGEYYTTGTRTRGSHGNIQHTNNRTYFGSNRA
ISLDQYSNNRRMSDGVPIQSVHSDNSVLYYHHQRQHRSLDHDTMCSSSDKSTSLNSTHDT
APGGDPTTILHVPPPQPPPPTGKQRLGKLFGSSSSSASGSAATSAVANLKNNNSAGHGCT
AVGGSASTSGGGGSGKHFSRMLSFNQQQRLDKLRNNNNSQSKNNNNNNTNNNGGGSSIGN
SNNNNNNNNNNSISNNKNAPAGSAAISQAKHLDGREAMHGAARICPGLGSAAGGDGGFDG
TISGSVGVGGGGNQDGGKGGNGSSSNGTAARTTAAAASTASAGSKSFLSRLRQFTGRLSF
NFDSRESKKLQLLAGNAPTDLKAKGASAGPKRDHRLEKSRTVDVGDLGPVAICGDSTMSG
QQAAIHQQQQQQQHQKQQHLSLVPGESFYGGGPPVVMNQPKSISPILMQHRHSEVLGLGG
AAGAAARSRAYSLDVPIGGRHCCRSLSGSTTGGGAGSSCGGSHKSLTFSLNNRSLTEDND
GGGSLALVSGERKSGVGVQPPPLRNNSLLLLADDPSSSSAAIGGGDGSAPPNETI
NT seq
4488 nt
NT seq
+upstream
nt +downstream
nt
atgtaccacaaggacggaaccgtagatgtgaagctattagccgaccttgggtacatagcc
gaccgtctccggaaccttgagcagaagtgggacttgaccgagctgaaggatctgcaccgg
cgcatcgtactcaagctcgacgatccgccgacgagcgtgctgcggcttagggaaacgctt
gcccgtacgccaaccgtaccgccgggctcccccgaccagcagtatcagcaggaagggcag
gaggagcttacgaacagcacgaaggagcaggaagacgcaggcctgcagctaccggtagta
atcatcgccgatgaagtaacgccacccagtgtgattgtagaggaatgtgcagaggcatct
gaagtgtcgccgacagccgaccgtggggatgatgaatttggcgaaagtagcaaccaaagc
aacagcgtccaggatgttggcaatgttgaggaaagcgttcgcaaactagaccagctagag
gagctggtaattgccttctatcacagctgtggccgacgcagttcgcgcgggtgtgccgac
accgagcagacggccagtgaagcggtacgcgacggagcgagccgggcacgggcgaaacga
accaaaaagagacagcagcaatcgagcggggaagcgtgcccaggggcgtaccatccagat
cagcagcaccagaagcggcaccccgatccggatcgtactatgaaccaaggcaccgacccg
gaccaggatcgggatcatctcgcacacgcagcagcagcagcagcaacgtcagcaccatcc
gacaccagtgccgtccccgtcggcgacggtcgacagcaggcacaaccgcaaccgttacgc
tcgatccacgctgacgcacctgaaccgggatattgcctcgaccgggacgtgccgcttgac
gacgaggaggacacggtcacactgacggcggaaacgagcagcgaatgctgcagccagcaa
acggtcgttgcagtggtggcggaggaggaggagggggaggaggcggaggcggaggaagtg
gtagaagacggatcatcgcccggtcacgatccgaccgaaacggtcgccccgggcagtgat
acgaccacggacgacgaggtcgagaacgacgatacgggcggttctgacgcggatgcaaac
gatgaggcggaaccgggcgacacgtgcaccaggcgaaccgtgctagggcaggactcgacg
ccgtcctcccgccggtgttcgctcggtggcgagtttgagacggagcagaaccggcgcctc
cgccgccggctgtccgagctgacgaacaacttctgcacgccgaaacagttccagcagctg
tgcgacaatttggacagcattaccgacaacgatctgaagctgctggtccgggagctcaag
cgaaagatcgaatttgccgaaaggatgaactggctttgtctatcgagcagaccgcgcggt
ccaccgcaccggaaaactagcctaccaaagcacacggacgtcaagaagcgcttcctggaa
acgtgcgacaagacgctgtcggacgaggtgaaggccgccctgcggcttccggcgttcgat
tcgtacgaatgggaggactgggacgtgatccacctgatgcagacgatgtttgtcgagctg
aatctgctggagaagttcaacataccgatcgtgacgctgcgcgagtggctgtacgaggtg
tacaagcactacaacgatgtgccgttccacaactaccgccactgcttctgtgtcgcccag
atgatgtacaccattgcctggcacacgaacctggtgcagcggttaggcgagctggaggtg
ttggtcctgctggtgtcctgcatctgccacgatttggaccaccccggttacaacaacatc
taccagataaacgcacgcaccgagctggcattaaggtacaatgatatttcaccgctggaa
aaccatcactgttcgatcgcgttccgactgctggagcacccggaatgcaacatatttcgc
aacatgagcaaggagatgtacaaagatgtacgcgagggaattatccggtgcatattggcc
accgatatggcccgacataacgaaatcctcacccagtttcaggaggctacacccgagttc
gactacagcaacaaagtgcacacgaatttgctctgcatggttctgatcaaggtggcagac
atttcgaacgaggcgcgaccgatggacgtggcggaaccgtgggtcgaccggctgctgcag
gagtttttcgcgcagagcgccgcagaaaagtccgagggtctgccggtgacaccgttcatg
gatccggacaaggtgtcgaaaccgggcagccaggtacggttcatcgggctggtgctgttg
ccgctgttcgaagccctcggcgagctgttgcccgagctgacggatctgatcatcacgccg
gtgcgcgttgccctcgactactatcgccgactgaacgatgcagccaacaagacgcgccgc
tcgatcgcggaagcagaggccgcatcgtccgagagcggcggctcaccgcagctgccccgt
tcccagtccggcatcagcgtcaaatcgcgacgtagtattccctcgcaaaagtccgcatct
cgcacgtctgttgatgagcctattttaattgcagccgaactgcacgacctaccggagggc
agcgagagtggcgactccgagacggccaccgaagtcgacgtggcggaaaaaacgtccaag
ttcaaggtggacacggaaagcatccaccgcaaacagtcgcacccgaactcccggaagggt
agccgcgagaagcgcccgtcgatgatcggtgaatactacaccacaggtacgcgcacccgt
ggctcccacggcaacatacagcatactaataatcgcacgtattttggttcgaatcgcgcc
atcagcctagaccagtacagtaacaaccggcgcatgtccgacggcgtcccgatacagtcg
gtccactcggacaacagcgtgctgtactaccatcaccagcggcagcaccgcagcctcgac
cacgacaccatgtgctcgtcgtcggacaaaagcaccagcctgaacagcacgcacgacacg
gcgccgggcggcgacccgacgaccatcctgcacgtgccaccgccgcaaccgccaccgccg
acgggaaagcagcggctcggcaagcttttcggtagcagcagcagcagcgcgtcgggcagc
gccgccacctccgccgtggcgaatctgaagaacaataatagcgccggtcacgggtgcacg
gccgtcggcgggtccgcatcgactagcggtggtggtggttccggtaaacattttagccgt
atgttgagcttcaaccagcagcaacggctggacaagctgcgcaacaacaataacagccag
agcaagaataacaacaacaacaacacgaacaacaatggcggcggcagcagcattggcaac
agtaacaataataataacaataacaataacaatagcattagcaacaataagaacgcaccg
gccggcagtgcggccatcagccaggcgaagcatctcgatgggcgtgaggcaatgcacggg
gcggcccgcatatgccccggcctcggcagtgccgccggtggggacggtggattcgacggg
accatttccgggagtgtcggcgtcggcggcggcggtaatcaggacggcggcaagggtggc
aatggcagcagtagtaacggcacggcggctcgaacaacggcagccgcggcctccaccgcg
tcggccggttcgaaatcgttcctgtcccggctgcgacagtttaccggccggctgagcttc
aactttgactcgcgggaatcgaagaagctgcagctgctggcggggaacgcaccgaccgac
ctgaaggcgaaaggcgcctcggccgggccaaagcgggaccatcggctggagaagtcgcgc
acggtcgacgtgggcgacctgggaccggtagcgatctgtggcgacagcacaatgtccggc
cagcaggcggccattcaccagcagcagcagcagcagcagcaccagaagcagcagcatctc
tcactcgtcccaggtgagtccttctacggtggaggaccgccggtagtaatgaaccagccg
aaatcaatctcgcccatccttatgcagcaccgccacagtgaggtgctcggtttgggcggt
gcagcgggggcggccgcccgcagccgcgcctacagcctggacgtcccgatcgggggccgg
cactgttgccgcagtctcagcggtagcacgaccgggggcggtgccggttccagctgcggt
ggcagccacaagagtctcacgttttcgctcaacaatcgctcgctgacggaggacaacgac
gggggcggcagcctggcgctcgtgtccggcgagcgaaagtcgggcgttggggtgcagccg
ccgccgctgcgcaacaactcgctgctgctgcttgcggacgatccgtcctcgtcgtcggcc
gccattggcggtggtgatggtagtgcgccaccgaacgaaaccatatga
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