Actinosynnema mirum: Amir_0840
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Entry
Amir_0840 CDS
T00957
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
ami
Actinosynnema mirum
Pathway
ami00860
Porphyrin metabolism
ami01100
Metabolic pathways
ami01110
Biosynthesis of secondary metabolites
ami01120
Microbial metabolism in diverse environments
ami01240
Biosynthesis of cofactors
Module
ami_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
ami_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
ami_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
ami00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Amir_0840
Enzymes [BR:
ami01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Amir_0840
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
ACU34801
UniProt:
C6WM67
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All DBs
Position
923932..925077
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AA seq
381 aa
AA seq
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MAGGGAAAAGPLAGFTVGVTAARRAEELVALLERKGAAVLHGPAIRIVPLHDDAKLLEAT
ELVLARQVDAVVATTGIGFRGWVEAAEGWGLGDRLLTALGDGLLLARGPKARGAVRAAGL
VEDWSPSSESNAELLEHLLGLGVAGKRIAVQLHGIPLPEFTGALREAGAEVVEVPVYRWT
GPADPGPLERLLEGVLSGQVDAMTFTSAPAAASVLETARQMGRYEEVLAALRRVLVVCVG
AIAAGPLVAVGVPVVQPGRARMGALAREVVVELPARAVRVPVEGREIELRGQGVLVDGEL
RPVAPAPMAVLRALVEARGRVVSRKELLAALPGGGEEHAVETAVGRLRTALGDPGVVATV
VKRGYRLAVEPSRFECGGVAV
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
gtggcgggcgggggtgctgccgctgccgggccgctcgcggggttcacggtgggggtcacc
gcggctcggcgggccgaggagctggtggcgctgctggagcggaagggcgctgcggtgctg
cacgggcccgcgatccggatcgttccgctgcacgacgacgcgaagttgttggaggccacc
gagctggtgctcgcccggcaggtcgacgcggtcgtggccaccaccgggatcgggttccgg
gggtgggtcgaggccgcggaggggtgggggctcggggatcggttgttgacggcgctcggg
gacgggttgctgttggcgcgggggcccaaggctcggggggctgtgcgggctgccgggctg
gtggaggactggtcgccttccagcgagtccaacgccgagcttctggagcatttgttgggg
ttgggggtggcggggaagcggatcgcggtgcagttgcacgggattccgctgccggagttc
accggggcgttgcgggaggccggggccgaggtggtggaggtcccggtctaccggtggacc
gggcccgctgacccggggccgttggagcggttgttggaaggggtgctgtcggggcaggtg
gacgcgatgacgttcacgtccgcgcctgcggcggcgtcggtgctggagacggcccggcag
atggggcggtacgaggaggtgctcgccgcgttgcggcgggtgctggtggtgtgcgtgggg
gcgatcgcggccgggccgctggtggcggtgggggttccggtggtgcagccggggcgggcg
cggatgggggcgttggctcgggaggtggtggtggagcttccggctcgggcggttcgggtt
ccggtggaggggcgggagatcgagctgcgggggcagggggtgctggtggacggggagttg
cggccggtcgcgcccgcgcccatggcggtgctgcgggcgttggtggaggcgcgggggcgg
gtggtgtcgcggaaggagttgttggcggcgttgccggggggtggggaggagcacgcggtg
gagacggcggtggggcggttgcggactgcgctcggggatccgggggtggtggcgaccgtg
gtgaagcgggggtaccggttggccgtcgagccgtcgcggttcgagtgcggtggggtggcg
gtgtga
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