Actinosynnema mirum: Amir_1166
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Entry
Amir_1166 CDS
T00957
Name
(GenBank) FolC bifunctional protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ami
Actinosynnema mirum
Pathway
ami00790
Folate biosynthesis
ami01100
Metabolic pathways
ami01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ami00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Amir_1166
Enzymes [BR:
ami01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Amir_1166
6.3.2.17 tetrahydrofolate synthase
Amir_1166
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ACU35121
UniProt:
C6WQ65
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All DBs
Position
1300362..1301720
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AA seq
452 aa
AA seq
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MSFEPGALGILSVVEAELDKRWPETKIEPSLDRIRALVDVLGEPQKAYPVIHVGGTNGKT
STARMVEALLTRVGLRTGRYTSPHLQLATERISVDGAPISPEQYVEAYRDVKPYVSIVDS
RGDVPMSKFEVLTGMAFAAFAETPVDVAVVEVGLGGSWDATNVADGRVAVITPIGIDHVE
FLGDDLAGIAEEKAGIIKPGSTVVLAQQRPEAEQALLRRVAEVDATVARQGSEFLVLRRD
VAVGGQMLRLQGLGGVYDEVFLPLHGAHQAANASLALAAVEAFFGAGPQRQLDVEAVREA
FAGVESPGRLERLRAAPAVLVDAAHNPHGAEALAKALDEEFGFRRLIAVVGVMSDKDAVG
ILTALEPRVAEVVLTQNSSPRAMDADHLAGVALPIFGEDRIVVQPNLADAIEDAVRMAED
TEDGLVSGGGVIVTGSVVTAGQARALFGKEPA
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgtcgttcgaaccgggggcgctcggcatcctcagcgtggtcgaggcggagctggacaag
cgctggcccgagaccaagatcgagccgagcctggaccggatcagggcgctggtcgacgtg
ctgggcgagccgcagaaggcctacccggtgatccacgtcggcggcaccaacggcaagacg
tcgaccgcgcgcatggtcgaggcgctgctcacgcgcgtcggcctgcgcaccggtcgctac
accagcccgcacctccagttggccaccgagcggatcagcgtcgacggggcgccgatcagc
ccggagcagtacgtcgaggcgtaccgggacgtgaagccgtacgtgtccatcgtggactcg
cgcggcgacgtgccgatgagcaagttcgaggtgctcaccggcatggcgttcgcggcgttc
gcggagacgccggtcgacgtggccgtggtcgaggtcggcctcggcggctcctgggacgcc
acgaacgtggccgacgggcgggtcgccgtgatcaccccgatcgggatcgaccacgtcgag
ttcctgggtgacgacctggcgggcatcgcggaggagaaggccgggatcatcaagcccggt
tccaccgtcgtgctcgcgcagcagcgaccggaggccgagcaggcgctgctgcgccgggtc
gccgaggtcgacgcgacggtggcgcggcagggctcggagttcctggtgctgcggcgcgac
gtcgcggtcggcggccagatgctcaggctgcagggcctcggcggcgtgtacgacgaggtg
ttcctgccgctgcacggcgcgcaccaggcggccaacgcgtcgctggcgctcgccgccgtc
gaggcgttcttcggcgccgggccgcagcggcagctcgacgtggaggcggtgcgcgaggcg
ttcgcgggcgtcgagtcgccgggcaggctggagcggctgcgcgccgcgcccgccgtgctg
gtcgacgccgcgcacaacccgcacggcgccgaggcgctggcgaaggcgctcgacgaggag
ttcggcttccgcaggctcatcgcggtcgtcggcgtcatgtccgacaaggacgccgtcggc
atcctgaccgcgctggagccgagggtggccgaggtcgtgctgacccagaactcctcgccg
agggccatggacgccgaccacctggcgggcgtggcgctgccgatcttcggcgaggaccgc
atcgtcgtgcagccgaacctggccgacgcgatcgaggacgcggtccgcatggcggaggac
accgaggacggcctggtgtccggcggaggcgtcatcgtgaccggctccgtggtgacggcg
gggcaggcccgcgccctgttcgggaaggaaccggcatga
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