Actinosynnema mirum: Amir_5770
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Entry
Amir_5770 CDS
T00957
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ami
Actinosynnema mirum
Pathway
ami00300
Lysine biosynthesis
ami00550
Peptidoglycan biosynthesis
ami01100
Metabolic pathways
ami01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ami00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Amir_5770
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Amir_5770
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Amir_5770
Enzymes [BR:
ami01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Amir_5770
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Paralog
Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
wHTH-HSP90_Na-assoc
Motif
Other DBs
NCBI-ProteinID:
ACU39583
UniProt:
C6WDE6
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Position
complement(6802362..6803834)
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AA seq
490 aa
AA seq
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MITLTLAEIAEIVGGRLHGTDGSPVVKAGVEFDTRKLLPGGLFLALPGERVDGHDFAAAA
VAAGAAGVLAGREVPAPSVIAPPVAPADEHEGAYVLSGDSDGSGAAVLAALGKLARHVTD
RLTAGGLTVVGVTGSSGKTSTKDLIAQVLSPTGATIAPPGSFNNELGHPWTALRADEDTG
YLVLELSARGPGHIADLCAVAPPRIGAVLNVGTAHLGEFGSREGVARTKGELVEALPEDG
VAVLNADDPLVLAMAERTKAKVVLVGEHSRAQVRAVDIVLDEQARPGFTLLTPHGSARVQ
LAVHGPHQVGNALTAAAVALELGATPQQVADRLGSAKPISAHRMEVVDRADGVTVVNDAY
NANPESVKAALKSLATISRSTTPARRSWAVLGPMAELGADSVRAHDEIGRLAVRLDVNRL
VVIGDDARAMHQGAHLEGSWGEESILVPDVAAAIELLRDEVRPGDVVLVKASNSYGLWRV
AEALLEAGSK
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
gtgatcacgctgaccctcgccgagatcgccgagatcgtcggcggcaggctgcacggcacc
gacggctcgcccgtcgtgaaggcgggcgtcgagttcgacacccgcaagctgctgcccggc
gggctgttcctggccctgcccggcgagcgggtcgacggccacgacttcgccgccgccgcc
gtcgcggcgggcgccgcgggcgtgctggcgggccgcgaggtccccgcgccctcggtgatc
gccccgccggtcgccccggccgacgagcacgagggcgcctacgtgctgtccggcgacagc
gacggctccggcgccgccgtgctcgccgcgctgggcaagctcgccaggcacgtcaccgac
aggctcaccgcgggcgggctgaccgtcgtgggcgtcaccggctcctccggcaagacgtcc
accaaggacctcatcgcccaggtgctgtccccgacgggcgccacgatcgccccgcccggc
tcgttcaacaacgagctggggcacccctggaccgcgctgcgcgccgacgaggacaccggc
tacctcgtgctggagctgtccgcgcgcggtcccggccacatcgccgacctgtgcgccgtc
gcgcccccgaggatcggcgcggtgctcaacgtcggcaccgcgcacctgggcgagttcggc
tcccgcgagggcgtcgcgcgcaccaagggcgagctggtcgaggccctgcccgaggacggc
gtcgcggtgctcaacgccgacgacccgctcgtgctggccatggccgagcgcacgaaggcg
aaggtcgtgctcgtcggcgagcacagcagggcgcaggtccgcgcggtcgacatcgtcctc
gacgagcaggcccgccccggtttcaccctcctcaccccgcacggcagcgcgcgcgtccag
ctcgccgtgcacggtccccaccaggtcggcaacgcgctcaccgccgccgccgtcgcgctg
gagctcggggcgacgccccagcaggtcgccgaccggctcggctcggcgaagccgatctcc
gcgcaccgcatggaggtcgtcgaccgcgccgacggcgtcacggtcgtcaacgacgcctac
aacgccaacccggagtcggtgaaggccgcgctgaagtcgctggccaccatctcccgctcc
accacccccgcgcggcgcagctgggccgtgctggggccgatggcggagctgggggccgac
tcggtgcgcgcgcacgacgagatcggcaggctcgcggtgcgcctggacgtcaaccggctg
gtcgtcatcggtgacgacgcccgcgcgatgcaccagggagcgcacctggaaggatcatgg
ggcgaggaatcgatcctggtgccggatgtcgctgcggcgatcgaactgctgcgcgacgag
gtgcggcccggtgacgtcgttctggttaaggcatccaactcatacggcctgtggcgggtt
gccgaggctctcctggaggcgggcagcaagtga
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