Actinosynnema mirum: Amir_6013
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Entry
Amir_6013 CDS
T00957
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ami
Actinosynnema mirum
Pathway
ami00290
Valine, leucine and isoleucine biosynthesis
ami00620
Pyruvate metabolism
ami01100
Metabolic pathways
ami01110
Biosynthesis of secondary metabolites
ami01210
2-Oxocarboxylic acid metabolism
ami01230
Biosynthesis of amino acids
Module
ami_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ami00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Amir_6013
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Amir_6013
Enzymes [BR:
ami01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Amir_6013
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ACU39820
UniProt:
C6WG56
LinkDB
All DBs
Position
complement(7058458..7060071)
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AA seq
537 aa
AA seq
DB search
MTTLGDSFHVYDTTLRDGAQREGITYSVTDKLQVARLLDGLGVGFIEGGWPGAMPKDTEF
FARAASGELELSSAKLVAFGATRKAGVKVQDDPQVRALLDSQAPVVTLVAKSDLRHVERA
LRTDATENLAMVHDTVKHLVDNGRRVFLDAEHFFDGFAHDPDTALRVLEAGVTGGADVVV
LCDTNGGQLPLGLAEVVADVIARTGFRVGIHCQDDTSCAVANTLAAVQAGATHVQCTANG
YGERAGNADLFAVVGNLVTKLGMPVLPEGAVGELTRVSHALAEIANIAPDTHQAYVGSSA
FAHKAGLHASAIKVDPLLYNHIDPEVVGNGMKILVTEMAGRASLELKGRELGVDLAANPE
ALTSAVRKVKELEAGGWSFEAADASLELLLRDELSELDAPPFTLESYRVVLDHRSDGEIG
SEATVKVHVGGERVIATAEGNGPVHALDGALRKALLPHLSWLDAVKLNDYKVRILSGDGR
DADGAGGTEAVTRVLVNSTDGEREWTTVGVHGNIVEASWLALCDALAHKAVHASALV
NT seq
1614 nt
NT seq
+upstream
nt +downstream
nt
gtgaccacgctcggcgatagcttccacgtctacgacaccaccctccgggacggcgcacag
cgcgagggcatcacctactccgtcaccgacaagctccaggtggcgcgcctgctggacggg
ctgggcgtcggcttcatcgagggcggctggccgggcgcgatgcccaaggacaccgagttc
ttcgcccgcgcggcctccggagagctggagctgtccagcgcgaagctggtcgcgttcggc
gccacccgcaaggcgggcgtgaaggtccaggacgacccgcaggtgcgcgccctgctcgac
tcgcaggcccccgtcgtcaccctggtggccaagtcggacctgcggcacgtggagcgcgcc
ctgcgcaccgacgccaccgagaacctcgccatggtccacgacaccgtcaagcacctggtg
gacaacggccgccgggtgttcctggacgccgagcacttcttcgacggcttcgcgcacgac
ccggacaccgcgctgcgcgtgctggaggcgggcgtcaccggcggggccgacgtggtggtg
ctgtgcgacaccaacggcggccagctgccgctcggcctggccgaggtggtcgcggacgtc
atcgcccgcaccggcttccgggtcggcatccactgccaggacgacacgtcctgcgccgtg
gcgaacaccctcgcggccgtgcaggcgggcgcgacgcacgtccagtgcaccgcgaacggg
tacggcgagcgggcgggcaacgccgacctgttcgccgtggtcggcaacctggtcaccaag
ctggggatgccggtcctgccggagggggccgtgggggagctcacccgcgtctcgcacgcc
ctcgccgagatcgccaacatcgcacccgacacccaccaggcctacgtcgggtcgtcggcc
ttcgcccacaaggcgggcctgcacgcgagcgcgatcaaggtcgaccccctgctgtacaac
cacatcgacccggaggtggtcggcaacggcatgaagatcctggtcaccgagatggccggg
cgggcgagcctggagctgaaggggcgggagctgggcgtggacctcgcggccaaccccgag
gccctgaccagcgccgtccgcaaggtcaaggagctggaggcgggcggctggtcgttcgag
gcggccgacgcgtcgctggagctgctgctgcgcgacgagctgtccgaactggacgccccg
ccgttcaccctggagtcctaccgcgtcgtgctcgaccaccgctcggacggggagatcggg
tccgaggcgacggtgaaggtgcacgtgggcggcgagcgggtgatcgccacggcggagggc
aacggcccggtgcacgcgctggacggggccctgcgcaaggcgctgctgccgcacctgtcc
tggttggacgcggtgaagctcaacgactacaaggtccgcatcctgtccggtgacgggcgg
gacgcggacggcgcaggcggcaccgaggcggtgacgcgggtgctggtgaactcgaccgac
ggcgagcgcgagtggaccacggtcggggtgcacggcaacatcgtcgaggcgagctggctg
gcgctgtgcgacgcgctggcgcacaaggccgtgcacgcgtccgcgctggtctga
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