Actinosynnema mirum: Amir_6983
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Entry
Amir_6983 CDS
T00957
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
ami
Actinosynnema mirum
Pathway
ami00280
Valine, leucine and isoleucine degradation
ami00640
Propanoate metabolism
ami00785
Lipoic acid metabolism
ami01100
Metabolic pathways
ami01110
Biosynthesis of secondary metabolites
ami01210
2-Oxocarboxylic acid metabolism
Module
ami_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ami00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Amir_6983
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Amir_6983
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Amir_6983
Enzymes [BR:
ami01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Amir_6983
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
ACU40776
UniProt:
C6WSA6
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Position
complement(8117805..8118998)
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AA seq
397 aa
AA seq
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MSSSEEWTHPGPDAVPATGAAPTAEQVIAGLKATDEGGSDLVQLLTPEGERVQHPDFAVD
VTAEELRGLYRDMVLVRRVDREANALQRKGELGLWAPLLGQEAAQVGAGRAMRARDMAFP
SYREHGVAWCRGVPPTDLLSMFRGTDQCGWDPVEHRFHPYTIVIGNQVLNATGYAMGQRF
DGAVGDDGGEATMAFFGDGATSQGDVHEGFVWAAVYDAPVVFFCQNNQWAISEPTERQSR
LPLYQRARGYGFPGIRVDGNDVLATLAVTRWALDQCRTGNGPVLIEAFTYRMDAHTTSDD
PSRYRLSDELELWKLKDPIERVKVHLVKQQWADQEFFDHVELEAEELGARLREHCSSLEA
PPAERIFSQVYAEGSPVVDAQRAEFLSYHAGFLGGER
NT seq
1194 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtcctcagaagaatggacgcaccccggtccggacgcagttccggcgaccggggcc
gcgccgaccgccgaacaggtgatcgccggtctcaaggccacggacgagggcggctccgac
ctggtgcagctgctcacccccgagggcgagcgggtccagcaccccgacttcgccgtcgac
gtcacggccgaggagctgcgcgggctgtaccgcgacatggtcctggtccgccgcgtcgac
cgcgaggccaacgcgctgcagcgcaagggcgagctcggcctctgggcgcccctgctcggc
caggaggccgcgcaggtcggcgccgggcgggcgatgcgggcgcgggacatggcgttcccc
agctaccgcgagcacggcgtcgcctggtgccggggcgtgcccccgaccgacctgctcagc
atgttccgcggcaccgaccagtgcggctgggacccggtcgagcaccgcttccacccctac
acgatcgtcatcggcaaccaggtgctcaacgccaccgggtacgccatgggccagcggttc
gacggcgccgtgggcgacgacggcggcgaggccaccatggcgttcttcggcgacggcgcc
accagccagggcgacgtgcacgagggcttcgtctgggcggccgtctacgacgcgccggtg
gtgttcttctgccagaacaaccagtgggccatctccgagcccaccgagcgccagtcccgg
ctcccgctctaccagcgggcgcgcggctacggcttccccggcatccgggtcgacggcaac
gacgtcctcgccaccctcgccgtcacgcgctgggcgctcgaccagtgccgcaccggcaac
ggccccgtcctgatcgaggcgttcacctaccggatggacgcccacaccacctcggacgac
ccgtcccgctaccggctctccgacgagctggagctgtggaagctcaaggaccccatcgag
cgggtcaaggtgcacctggtcaagcagcagtgggcggaccaggagttcttcgaccacgtc
gagctggaggccgaggagctcggcgcccggctgcgcgagcactgctcgtcgctggaggcc
ccgcccgccgagcggatcttcagccaggtgtacgcggagggcagcccggtcgtggacgcc
cagcgcgcggagttcctgtcctaccacgccggtttcctgggaggtgagcgctga
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