Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:aml00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
100463865 (HMBS)
Enzymes [BR:aml01000]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.61 hydroxymethylbilane synthase
100463865 (HMBS)
361 aa
MSGNGNLAAAAEENGPKMRVIRVGTRKSQLARIQTDSVVAMLKAFYPGLQFEIVAMSTTG
DKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPY
DAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFKSIRGNLNTRLRKLDEL
QEFSAIILAAAGLQRMGWQHRVGQILHPEECMYAVGQGALGVEVRAKDQDMLDLVGVLHD
PETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSMQETMQATIR
VTAQLEDGPEDDPQLVGITARNIPREAQLAAENLGISLASLLLNKGAKNILDVARQLNDA
H
